Thu.May 02, 2024

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Insulin sensitivity estimates and their longitudinal association with coronary artery disease in type 1 diabetes. Does it matter?

Cardiovascular Diabetology

Insulin resistance and chronic kidney disease are both associated with increased coronary artery disease risk. Many formulae estimating glucose disposal rate in type 1 diabetes infer insulin sensitivity from c.

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Dietary changes may treat pulmonary hypertension

Science Daily - Heart Disease

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death. The underlying reasons for this organ-specific vessel stiffening remained a mystery until researchers made a surprising discovery about these blood vessel cells in patients with pulmonary hypertension -- they're hungry.

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New Study Published in JACC: Heart Failure Reveals that Despite Significant Efforts to Improve Acute Heart Failure Treatment Over the Past 20 Years, Management Remains Unchanged

DAIC

Getty Images milla1cf Thu, 05/02/2024 - 10:17 May 2, 2024 — Reprieve Cardiovascular, Inc. (‘Reprieve’), a development stage company focused on pioneering an intelligent approach to acute decompensated heart failure (ADHF) treatment, today highlighted the publication of TREAT-AHF study results in JACC: Heart Failure. Heart failure (HF) is a leading cause of hospitalization in the United States.

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Young Adults More Likely to Believe Myths Related to Tanning, Sun Protection, Skin Cancer

HCPLive

These survey results indicate that young adults tended to embrace misconceptions regarding sun protection and positive views of tanning.

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Cardiologists Train Large AI Model to Assess Heart Structure, Function

DAIC

Cedars-Sinai and Smidt Heart Institute investigators developed a novel foundation model that integrates computer vision interpretation of echocardiogram images with natural language processing to augment cardiologists’ interpretation of echocardiograms. Image by Getty. milla1cf Thu, 05/02/2024 - 10:09 May 2, 2024 — Artificial intelligence experts at Cedars-Sinai and the Smidt Heart Institute created a dataset with more than 1 million echocardiograms, or cardiac ultrasound videos, and their corre

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Scientists identify new treatment target for leading cause of blindness

Science Daily - Stroke

Scientists report that a gene previously implicated in the development of atherosclerotic lesions in coronary arteries could be key to understanding why many people don't benefit from the most used therapy for neovascular age-related macular degeneration (AMD), a leading cause of blindness.

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BioCardia’s CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial Results Show Patient Benefits in Important Outcomes

DAIC

Getty Images milla1cf Thu, 05/02/2024 - 10:12 May 2, 2024 — BioCardia, Inc. , a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases, today announced the primary endpoint results of the open label roll-in cohort of the CardiAMP Cell Therapy in Chronic Myocardial Ischemia Trial. Study clinical cardiology leadership and members of the Executive Steering Committee, Dr.

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Study: Children with hypertension at higher long-term risk for serious heart conditions

Medical Xpress - Cardiology

Youth with high blood pressure are nearly four times more likely to be at long-term risk of serious heart conditions including stroke and heart attack, according to a new study. The research, led by McMaster University, will be presented at the Pediatric Academic Societies (PAS) 2024 Meeting, held May 2–6 in Toronto.

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2024 AHA/ASA Performance and Quality Measures for Spontaneous Intracerebral Hemorrhage: A Report From the American Heart Association/American Stroke Association

Stroke Journal

Stroke, Ahead of Print. The American Heart Association/American Stroke Association released a revised spontaneous intracerebral hemorrhage guideline in 2022. A working group of stroke experts reviewed this guideline and identified a subset of recommendations that were deemed suitable for creating performance measures. These 15 performance measures encompass a wide spectrum of intracerebral hemorrhage patient care, from prehospital to posthospital settings, highlighting the importance of timely i

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Dietary changes may help treat pulmonary hypertension

Medical Xpress - Cardiology

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death.

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Pulmonary transplant complications: a radiologic review

Journal of Cardiothoracic Surgery

Lung transplantation has become the definitive treatment for end stage respiratory disease. Numbers and survival rates have increased over the past decade, with transplant recipients living longer and with gre.

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No benefit of apoA-I infusion after myocardial infarction

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 03 May 2024; doi:10.1038/s41569-024-01031-z In the AEGIS-II trial, infusion of apolipoprotein A-I to increase cholesterol efflux capacity did not improve outcomes in patients with acute myocardial infarction.

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How Much Does a CT Scanner Cost?

Cassling

Your healthcare facility has decided to invest in a new computed tomography (CT) scanner; now you’re in the process of evaluating your options. While considering variables like imaging capabilities, workflow efficiency, and patient experience, you’re also crunching numbers tied to cost. If you’re asking the question ‘how much does a CT scanner cost?

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FDA Update: Agency Qualifies Apple AFib History Feature as an MDDT

American College of Cardiology

The U.S. Food and Drug Administration (FDA) announced on May 1 that the Apple Atrial Fibrillation (AFib) History Feature now qualifies as a Medical Device Development Tool (MDDT) to assess AFib burden estimates within clinical studies.

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Cardiology Month in Review: April 2024

HCPLive

The April 2024 cardiology month in review spotlights FDA news and top updates from the American College of Cardiology 2024 Scientific Session.

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Transradial PCI Finally Normalized in the U.S., Though Holdouts Remain

Med Page Today

(MedPage Today) -- LONG BEACH, Calif. -- Radial artery access has become the dominant approach for percutaneous coronary intervention (PCI), with real-world practice supporting the safety benefits of this strategy, according to registry data.

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Vaping Frequency in Teen Years Connected to Risk of Exposure to Toxic Lead, Uranium

HCPLive

These data suggest vaping poses potential threats to the development of the brain and organs, with teenagers being a predominant target due to surges in use.

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LGE CMR and Sudden Death in Hypertrophic Cardiomyopathy

American College of Cardiology

What is the prognostic value of extent of late gadolinium enhancement (LGE) in predicting sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM)?

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Hematology Month in Review: April 2024

HCPLive

Our April month in review for hematology breaks down the latest updates to the pipeline, mortality risk in people with sickle cell disease, and our newest multimedia offerings.

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Ion channel Piezo1 activation aggravates the endothelial dysfunction under a high glucose environment

Cardiovascular Diabetology

Vasculopathy is the most common complication of diabetes. Endothelial cells located in the innermost layer of blood vessels are constantly affected by blood flow or vascular components; thus, their mechanosens.

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Nephrology Month in Review: April 2024

HCPLive

This month in review highlights top coverage of the latest news in nephrology, ranging from new clinical trial data in IgAN to research about kidney disease management.

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Pre-hospital glycemia as a biomarker for in-hospital all-cause mortality in diabetic patients - a pilot study

Cardiovascular Diabetology

Type 2 Diabetes Mellitus (T2DM) presents a significant healthcare challenge, with considerable economic ramifications. While blood glucose management and long-term metabolic target setting for home care and ou.

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Patients with new AS, PSA, RA Diagnosis Have High Reliance on Opioids

HCPLive

Patients often rely on opioids a year before and a year after a diagnosis of ankylosing spondylitis, psoriatic arthritis, or rheumatoid arthritis.

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Association of non-insulin-based insulin resistance indices with disease severity and adverse outcome in idiopathic pulmonary arterial hypertension: a multi-center cohort study

Cardiovascular Diabetology

Insulin resistance (IR) plays an important role in the pathophysiology of cardiovascular disease. Recent studies have shown that diabetes mellitus and impaired lipid metabolism are associated with the severity.

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miR-200b-3p relieved inflammation in patients with heart failure by regulating ZEB1 expression

Journal of Cardiothoracic Surgery

MicroRNA-200b-3p (miR-200b-3p) plays a pivotal role in inflammatory responses and is implicated in various inflammatory disorders. In this study, we aim to explore the role of miR-200b-3p in the inflammatory r.

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Lymphomonocytic inflammatory infiltrate with numerous eosinophilic granulocytes in the interstitium in a surviving heart transplant recipient: a case report

Frontiers in Cardiovascular Medicine

Findings of eosinophilic and lymphomonocytic inflammatory infiltrates in endomyocardial biopsies (EMBs) may help in myocardial disease diagnosis identification. Eosinophilic myocarditis (EM), a rare condition, is fatal if left untreated and has rarely been described in heart transplant recipients. An extensive work up is necessary to achieve an early etiological diagnosis; however, the underlying cause remains unexplained in nearly one-third of the patients.

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Study on risk factors and treatment strategies of hypoxemia after acute type a aortic dissection surgery

Journal of Cardiothoracic Surgery

Acute type A aortic dissection is a life-threatening cardiovascular disease characterized by rapid onset and high mortality. Emergency surgery is the preferred and reliable treatment option. However, postopera.

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Gene therapy treatment increasing body's signal for new blood vessel growth shows promise

Medical Xpress - Cardiology

Final 12-month data from the EXACT trial demonstrates safety and efficacy results for a vascular endothelial growth factor (VEGF) gene therapy treatment for patients who have advanced coronary artery disease (CAD). The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions.

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Metformin, Statins May Reduce Hepatocellular Carcinoma Risk After HCV Treatment Failure

HCPLive

Findings suggest metformin and statins have a potective effect against HCC in patients with HCV who fail antiviral therapy.

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Novel score system accurately identifies lesions, reducing risk of percutaneous coronary intervention complications

Medical Xpress - Cardiology

New data demonstrated that a left main (LM) bifurcation-specific novel scoring system (LM V-RESOLVE), based on three simple baseline angiographic findings, could help to rapidly discriminate lesions at risk of side branch (SB) occlusion during LM bifurcation percutaneous coronary intervention (PCI)—reducing risk during the procedure.

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Ophthalmology Month in Review: April 2024

HCPLive

This month's review focuses on digital technology use in ophthalmology, the association between vision impairment and mental health, and public health impacts in eye care.

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Fatigue, weakness and pelvic pain: Vascular problems are different for women

Medical Xpress - Cardiology

Feeling more tired than usual? Experiencing pelvic pain? It could be a problem with your arteries and veins.

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ReNu Achieves Primary Endpoint in Phase 3 Trial for Knee Osteoarthritis

HCPLive

At 6 months, patients treated with ReNu exhibited significant reductions in assessed knee pain and maintained patient function compared with controls.

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Radial arterial access found superior to femoral access in percutaneous coronary intervention

Medical Xpress - Cardiology

New data demonstrate the superiority of radial arterial access compared to femoral arterial access for coronary interventions. Findings showed radial access was associated with lower rates of in-hospital mortality, major access bleeding, and other major vascular complications compared with femoral access. The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions.

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Biosimilars Month in Review: April 2024

HCPLive

The biosimilars month in review reflects ongoing efforts to address key challenges in rheumatic disease treatment.

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New studies reveal underrepresentation of women and Hispanic population in the treatment of peripheral artery disease

Medical Xpress - Cardiology

New study findings underscore gaps in clinical trial representation of women and Hispanics for peripheral artery disease (PAD) and chronic limb-threatening ischemia (CLTI) research. All studies were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions.

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Fine-tuning early rhythm control strategies for atrial fibrillation – Timing matters to stay in sync

HeartRhythm

Rhythm control with either medications or catheter ablation is an established strategy for symptomatic patients with atrial fibrillation (AF), by reducing arrhythmic burden and improving patient quality of life, as well as reducing the risk of heart failure hospitalization and mortality in select populations with concomitant AF and heart failure. The 2023 ACC/AHA/ACCP/HRS guideline on AF management also underscores the role for early rhythm control in patients with recent AF diagnosis (< 1 year)