Thu.Aug 22, 2024

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Weight loss drug's heart benefits extend to people with heart failure

Science Daily - Heart Disease

The researchers looked at data from 4,286 people -- out of a total of 17,605 from the landmark Semaglutide and Cardiovascular Outcomes (SELECT) trial who were randomly assigned either semaglutide or a placebo -- who were followed up over an average of more than three years.

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ECG Blog #444 — CP and Aberrant SVT?

Ken Grauer, MD

The ECG shown in Figure-1 — was obtained from an older man with “CP” ( C hest P ain ) for the past 2 days. BP = 80/50 mm/Hg. Adenosine 6 mg IV was tried without response. QUESTIONS: How would YOU interpret this ECG? Your thoughts regarding optimal management? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ).

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Unvaccinated People at Risk of Facing Mental Illness Up to a Year After COVID-19

HCPLive

A new study found unvaccinated people have a greater risk of depression or serious mental health illnesses compared to vaccinated people.

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Counseling for PAD Walking Issues Might Hold Cardiovascular Benefit

Med Page Today

(MedPage Today) -- While counseling about walking did not increase step counts for people with peripheral artery disease (PAD), it still was linked to cardiovascular prevention in a post hoc analysis of a small randomized trial. After a few sessions.

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Quitting Smoking Lowers Risk of Hidradenitis Suppurativa, New Study Reveals

HCPLive

A study involving 6.2 million patients found smoking increases the risk of developing hidradenitis suppurativa, with quitting smoking significantly reducing this risk.

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Updated ACC/AHA Performance Measures and Quality Metrics for Heart Failure Care

NEJM Journal Watch - Cardiology

A joint organizational writing group has identified three new performance measures and six new quality measures to characterize care for the syndrome.

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Study Highlights Top 5 Inflammatory Biomarkers, Relationship with Atopic Dermatitis Severity

HCPLive

These data on systemic inflammatory biomarkers for patients with eczema may allow for more targeted treatments and for greater personalization of medicine for this skin condition.

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Doc Never Heard Patient's Screams; How Richard Simmons Died; Suicides in Physicians

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. A Florida doctor who wasn't wearing his hearing aids when he began performing a colonoscopy on a patient who wasn't fully sedated didn't hear the patient screaming.

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Nanox Receives FDA Clearance for Upgraded Version of Advanced AI Cardiac Solution

DAIC

tim.hodson Thu, 08/22/2024 - 10:12 Aug. 21, 2024 — NANO-X IMAGING LTD recently announced that its deep-learning medical imaging analytics subsidiary, Nanox.AI, received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for HealthCCSng V2.0. HealthCCSng V2.0 is the upgraded version of Nanox.AI’s cardiac solution, HealthCCSng, which has already shown tangible results in several healthcare systems, identifying patients at high risk of coronary artery disease while driving significan

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Day in the Life of a Doctor: Cardiology

Med Page Today

(MedPage Today) -- Internal medicine and rheumatology specialist Siobhan Deshauer, MD, spends a day in the hospital as a locum tenens physician and treats a patient with chest pain. Following is a partial transcript of the video (note that.

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ASCVD Risk Estimates Using the PREVENT Equations

American College of Cardiology

How do the national estimates of 10-year atherosclerotic cardiovascular disease (ASCVD) risk using the 2013 pooled cohort equations (PCEs) compare to the Predicting Risk of Cardiovascular Disease Events (PREVENT) equations regarding recommendations for statin in primary prevention?

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Combination Ezetimibe, Statin Therapy Superior in Reducing LDL-C Levels

HCPLive

Combination therapy with ezetimibe led to a greater reduction in LDL-C levels than statin monotherapy, but no significant effect on MACE outcomes.

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Long-Term Results Following Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients with Severe Aortic Stenosis: A Systematic Review and Meta-Analysis of Randomized Trials

The American Journal of Cardiology

Publication date: Available online 22 August 2024 Source: The American Journal of Cardiology Author(s): Rodolfo Caminiti, Alfonso Ielasi, Giampaolo Vetta, Antonio Parlavecchio, Domenico Giovanni Della Rocca, Mattia Glauber, Maurizio Tespili, Giampiero Vizzari, Antonio Micari

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SELECT: Semaglutide's CV Benefit Extends to Heart Failure Patients

HCPLive

A subgroup analysis of the SELECT trial confirmed semaglutide 2.4 mg benefits patients with heart failure across ejection fraction spectra, improving MACE and heart failure outcomes.

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Ticagrelor monotherapy after short duration of dual antiplatelet therapy compared to continued dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions: an updated meta-analysis

Coronary Artery Disease Journal

Background The optimum duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in patients with acute coronary syndromes (ACS) remains controversial. Ticagrelor monotherapy after short duration of DAPT (1–3 months) is a subject of research. We conducted an updated systematic review and meta-analysis comparing the ticagrelor monotherapy with continued DAPT after short duration of DAPT in patients with ACS undergoing PCI.

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Exploring the Discrepancy Between Patient Perception and Disease Activity Assessments

HCPLive

Medical experts explore how patient perceptions of rheumatoid arthritis can differ from disease activity assessments and provide an example of hidden symptoms revealed through further probing, along with the impact of therapy adjustments on achieving remission.

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SEMA3A as a biomarker of primary ventricular fibrillation complicating STEMI

HeartRhythm

Neural and electrical remodeling are well documented in the acute setting of myocardial infarction (MI). Sympathetic nerve sprouting in the infarct border zone increases transmural dispersion of repolarization, promoting arrhythmias. Overexpression of Semaphorin3A (SEMA3A), a glycoprotein regulating sympathetic nerve growth, limited ventricular arrhythmias in a rat model of MI.1 Our objective was to determine whether systemic levels of SEMA3A are associated with ventricular fibrillation (VF) in

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Evaluating and Adjusting Rheumatoid Arthritis Treatment: Adhering to ACR Guidelines for csDMARDs and Advanced Therapies

HCPLive

A panel of medical experts explore how to evaluate and adjust rheumatoid arthritis treatment by adhering to ACR guidelines for conventional synthetic DMARDs and advanced therapies, focusing on optimizing patient care and treatment outcomes.

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Post-operative pain following cardiac implantable electronic device procedures: Pain is inevitable, suffering is optional.

HeartRhythm

In the midst of the current opioid crisis, the pain management predicament does not spare the field of interventional cardiology, most notably the need to treat postoperative pain following the implantation of cardiac implantable electronic devices (CIED), including pacemakers and defibrillators. In a non-randomized trial of 610 patients reported in today’s issue of Heart Rhythm, Markman et al compared the efficacy of intra-procedural pectoral nerve block to the standard of care involving subcut

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Pavel Strnad, MD: Considerations for Safe Alcohol Consumption in AATD

HCPLive

Strnad explains how although moderate alcohol consumption is likely tolerable in most individuals with AATD, careful monitoring of liver-related parameters is still important.

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Early Atrial Tachyarrhythmia Recurrences After Pulsed Field Ablation – Does a Blanking Period Still Exist?

HeartRhythm

A 3-month blanking period post atrial fibrillation (AF) ablation, during which early recurrences of atrial tachyarrhythmias (ERAT) were considered not to have a prognostic significance for long-term ablation success, has been considered historically by the guidelines. Although not proven, this concept was based on the perceived time to heal the inflammation and maturity of thermal lesions created with radiofrequency or cryo energy.

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Dialysis Extends Life in Older Adults with eGFR < 12 mL/min/1.73 m²

HCPLive

A new study reveals dialysis increases life expectancy but reduces time at home for older adults below the eGFR threshold of 12 mL/min/1.73 m².

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Collecting Duct Pro(Renin) Receptor Contributes to Unilateral Ureteral Obstruction–Induced Kidney Injury via Activation of the Intrarenal RAS

Hypertension Journal

Hypertension, Ahead of Print. BACKGROUND:Although the concept of the intrarenal renin-angiotensin system (RAS) in renal disease is well-described in the literature, the precise pathogenic role and mechanism of this local system have not been directly assessed in the absence of confounding influence from the systemic RAS. The present study used novel mouse models of collecting duct (CD)–specific deletion of (pro)renin receptor (PRR) or renin together with pharmacological inhibition of soluble PRR

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Poll Suggests Patients with Psoriasis Prefer Topicals to Injectable, Oral Medications

HCPLive

The Harris Poll evaluated patient preferences for psoriasis therapy, highlighting patient views through an online survey.

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JACC Scientific Statement Explores Physical Reverse Remodeling For Dilated Ventricles, VHD

American College of Cardiology

Structural interventions, including ventricular remodeling, for dilated ventricles and valvular heart disease (VHD), show promise in the management of structural cardiac abnormalities that may be resistant to traditional guideline-directed medical therapies, according to a JACC scientific statement published Aug. 19.

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New Research Suggests Molybdenum May Ward Off Hyperuricemia, Gout

HCPLive

Molybdenum’s antioxidative properties may help reduce systemic inflammation, ROS, and uric acid levels.

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CMS Seeks Feedback on Cardiac CT Billing and Payment

American College of Cardiology

The Centers for Medicare and Medicaid Services (CMS) summarized a recent billing edit change in the 2025 Hospital Outpatient Prospective Payment System (OPPS) proposed rule, which fixes an issue that previously prevented hospitals from reporting costs for cardiac computed tomography (CT) as cardiology services.

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Higher Thiazide Doses Reduce Urine Calcium, Prevent Kidney Stone Recurrence

HCPLive

Findings link greater thiazide doses to increased reductions in urine calcium and fewer subsequent symptomatic kidney stone events.

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Effect of mannitol on postoperative delirium in patients undergoing coronary artery bypass graft: a randomised controlled trial

Open Heart

Abstract Objective Postoperative delirium (POD), especially after cardiac surgery with cardiopulmonary bypass (CPB), is a relatively common and severe complication increasing side effects, length of hospital stay, mortality and healthcare resource costs. This study aimed to determine the impact of using mannitol serum in the prime of CPB for preventing the occurrence of delirium in patients undergoing coronary artery bypass surgery.

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Hydrogel-coated and active clearance chest drains in cardiac surgery: real-world results of a single-center study

Journal of Cardiothoracic Surgery

Cardiac surgery patients require chest drains for postoperative fluid drainage. Innovations in this field include chemical drain coating and manual clot extraction systems, aiming to provide reduced clotting a.

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Systolic blood pressure at age 40 and 30-year stroke risk in men and women

Open Heart

Background American and European guidelines define hypertension differently and are sex agnostic. Our aim was to assess the impact of different hypertension thresholds at the age of 40 on 30-year stroke risk and to examine sex differences. Methods We included 2608 stroke-free individuals from the Akershus Cardiac Examination 1950 Study, a Norwegian regional study conducted in 2012–2015 of the 1950 birth cohort, who had previously participated in the Age 40 Program, a nationwide health exam