Sun.Jul 28, 2024

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Ophthalmologists, Patients Hesitate to Switch to Anti-VEGF Biosimilars

HCPLive

Hesitancy with anti-VEGF biosimilars was identified in a survey among both ophthalmologists and patients with nAMD in Canada.

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Post-stent chest pain, revisited

Heart Sisters

Heart patients with persistent or recurrent post-stent chest pain present “an unmet clinical need”, according to the European Journal of Cardiology.

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Antiretroviral Abacavir Linked With Cardiovascular Events in REPRIEVE Trial

Med Page Today

(MedPage Today) -- People with HIV who took the antiretroviral drug abacavir (Ziagen) had an increased risk of major adverse cardiovascular events (MACE), according to an exploratory analysis of the REPRIEVE trial. Past use of abacavir increased.

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Sexual Dysfunction Common Among Patients with Psoriatic Arthritis

HCPLive

Most men (91.7%) and women (72.7%) with psoriatic arthritis exhibited sexual dysfunction.

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Potential new therapeutic target for HFpEF

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 29 July 2024; doi:10.1038/s41569-024-01066-2 A new small-molecule inhibitor of vasohibins reduces myocardial stiffness and improves diastolic relaxation in a rat model of HFpEF.

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Edwards Acquires JenaValve and Endotronix, Expands into Aortic Regurgitation and Heart Failure

CardiacWire

Edwards Lifesciences is going all-in on structural heart and heart failure, acquiring aortic valve-maker JenaValve Technology and implantable heart failure monitor company Endotronix for $1.2B and up to $445M in milestone payments. These two acquisitions could impact Edwards’ structural heart and heart failure portfolios in unique and meaningful ways… JenaValve’s Trilogy TAVR system doesn’t yet have FDA approval, but is CE Marked for both aortic regurgitation and aortic stenosis, which is notabl

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Mortality and cardiovascular events in diabetes mellitus patients at dialysis initiation treated with glucagon-like peptide-1 receptor agonists

Cardiovascular Diabetology

Glucagon-like Peptide-1 Receptor Agonists (GLP-1RAs) have demonstrated efficacy in improving mortality and cardiovascular (CV) outcomes. However, the impact of GLP-1RAs therapy on cardiorenal outcomes of diabe.

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Long-term management of recurrent in-stent restenosis

Cardiology Update

A recent study published in JACC: Cardiovascular Interventions has provided new insights into the long-term management of patients suffering from recurrent in-stent restenosis (ISR), a condition presenting notable challenges in cardiovascular treatment. With minimal data and guidelines available for repeat percutaneous coronary interventions (PCI), this research offers valuable guidance for clinicians.

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Delgocitinib Cream Effective Over 16 Weeks for Chronic Hand Eczema

HCPLive

These findings support delgocitinib’s clinical benefit as a possible medication option for individuals with moderate to severe chronic hand eczema.

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Lessons from PROMINENT and prospects for pemafibrate

Cardiovascular Diabetology

The neutral result of the PROMINENT trial has led to questions about the future for pemafibrate. This commentary discusses possible reasons for the lack of benefit observed in the trial. There were, however, i.

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IGFBP7: From Senescence Biomarker to a Vaccine for Heart Failure

Circulation

Circulation, Volume 150, Issue 5 , Page 390-392, July 30, 2024.

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Antithrombotic treatment regimens in patients undergoing percutaneous coronary revascularization requiring oral anticoagulation: what real-world evidence shows us

Journal of Cardiovascular Pharmacology

An abstract is unavailable. This article is available as a PDF only.

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Myocardial Regeneration: Feasible or Fantasy?

Circulation

Circulation, Volume 150, Issue 5 , Page 347-349, July 30, 2024.

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Two troubling medical quotes in series …

Dr. S. Venkatesan MD

One Two

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Correction to: 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Circulation

Circulation, Volume 150, Issue 5 , Page e105-e105, July 30, 2024.

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Extensive myocardial calcifications: a systematic literature review of a rare pathological phenomenon

Frontiers in Cardiovascular Medicine

IntroductionMyocardial calcifications (MC) represent a relatively rare pathological process, which may accompany different cardiovascular conditions and can be broadly categorized as dystrophic or metastatic. Myocardial infarction (MI) has been traditionally regarded as the main cause of MC overall; however, no updated comprehensive data on the relative incidence of different forms of MC is available.

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Letter by Katsouras Regarding Article, “Prognostic Significance of Different Ventricular Ectopic Burdens During Submaximal Exercise in Asymptomatic UK Biobank Subjects”

Circulation

Circulation, Volume 150, Issue 5 , Page e102-e103, July 30, 2024.

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Surgical intervention for lung cancer in patients aged 75 and above: potential associations with increased mortality rates—a single-center observational study

Journal of Cardiothoracic Surgery

Lung cancer, which is diagnosed two to three times more frequently in patients over the age of 70, is a leading cause of cancer-specific mortality. Given the elevated risk of morbidity and mortality, surgical.

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Response by Lambiase and van Duijvenboden to Letter Regarding Article, “Prognostic Significance of Different Ventricular Ectopic Burdens During Submaximal Exercise in Asymptomatic UK Biobank Subjects”

Circulation

Circulation, Volume 150, Issue 5 , Page e104-e104, July 30, 2024.

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