Mon.Oct 09, 2023

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Redefinición de riesgo, prevención y tratamiento de las enfermedades cardíacas

American Heart News - Stroke News

Recomendaciones destacadas: Un nuevo aviso presidencial de la American Heart Association identifica las fuertes conexiones entre las enfermedades cardiovasculares (ECV), las enfermedades renales, la diabetes tipo 2 y la obesidad, y sugiere redefinir.

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Wallenberg/Lateral Medullary Syndrome - A Case Report

BMH Medical Journal

Wallenberg syndrome or lateral medullary syndrome is due to acute stroke affecting the lateral medulla, most commonly due to the occlusion of the intracranial portion of the vertebral artery or the posterior inferior cerebellar artery. The infarcted segment is the lateral medulla, posterior to the inferior olivary nucleus. Even though it was first described in the year 1808 by Gaspard Vieusseux, a more detailed and vivid description of the disease was given by Adolf Wallenberg, in the year 1895.

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Do you know a stroke hero?

American Heart News - Stroke News

DALLAS, October 9, 2023 – Each year, approximately 800,000 people in the U.S. experience a stroke, according to the American Heart Association’s 2023 Heart Disease and Stroke Statistical Update. Individuals and groups making a difference in the stroke.

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Aldehyde dehydrogenase 2 preserves mitochondrial function in the ischemic heart: a redox-dependent mechanism for AMPK activation by thioredoxin-1

Journal of Cardiovascular Pharmacology

Aldehyde dehydrogenase 2 (ALDH2) protects the ischemic heart by activating AMP-activated protein kinase (AMPK) signaling. However, the molecular mechanisms linking ALDH2 and AMPK signaling are not fully understood. This study aimed to explore the potential mechanisms linking ALDH2 and AMPK in myocardial ischemic injury. An ischemic model was established by ligating the left anterior descending coronary artery in rats.

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¿Conoce a un sobreviviente de un derrame cerebral?

American Heart News - Stroke News

DALLAS, 9 de octubre de 2023 – Cada año, aproximadamente 800,000 personas en los EE. UU. experimentan un ataque o derrame cerebral, según la actualización de estadísticas sobre enfermedades cardíacas y derrames cerebrales de 2023 de la American Heart.

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The therapeutic potential of targeting ferroptosis in the treatment of mitochondrial cardiomyopathies and heart failure

Journal of Cardiovascular Pharmacology

Ferroptosis is a form of iron-regulated cell death implicated in a wide array of diseases, including heart failure, hypertension, and numerous cardiomyopathies. Additionally, mitochondrial dysfunction has been associated with several of these same disease states. However, the role of the mitochondrion in ferroptotic cell death remains debated. As a major regulator of cellular iron levels, the mitochondria may very well play a crucial role in the mechanisms behind ferroptosis, but at this point,

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Impact of COVID?19 in patients with heart failure with mildly reduced or preserved ejection fraction enrolled in the DELIVER trial

European Journal of Heart Failure

Impact of COVID-19 in patients with HF and mildly reduced and preserved ejection fraction. COVID-19, coronvirus disease-2019; HF, heart failure. Aim COVID-19 may affect clinical risk in patients with heart failure. DELIVER began before and was conducted during the COVID-19 pandemic. This study aimed to evaluate the association between COVID-19 and clinical outcomes among DELIVER participants.

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What is wrong with the NHS?

Dr. Malcolm Kendrick

9th October 2023 (With lessons from, and for, all other health services around the world) Whilst awaiting the Judgement on my libel trial – three months from the hearing and counting – I decided to write about things other than statins and cholesterol. Lest I damage our case in some unforeseeable way. I do this humbly, as a public service. To keep people informed, and perhaps amused.

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Cost-effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for Patients with Heart Failure in China: a new pillar in our pockets, but at what price?

Journal of Cardiovascular Pharmacology

Sodium-glucose cotransporter 2 (SGLT2) inhibitors represent one of the most important pharmacological innovations in the field of Cardiology of the last decades, having shown significant outcome improvement in all the heart failure (HF) spectrum. However, cost-effectiveness considerations should be made. This editorial discusses results of a cost-effectiveness study coming from China and focusing on patients affected by HF with reduced ejection fraction.

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One-Year Outcomes Following Stereotactic Body Radiotherapy for Refractory Ventricular Tachycardia.

HeartRhythm

Cardiac stereotactic body radiotherapy (SBRT) has emerged as a promising noninvasive treatment for refractory ventricular tachycardia (VT).

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No Significant Change in Trend of Hospitalizations for Acute Coronary Syndrome in Japan Before and After Introduction of Heated Tobacco Products

Circulation: Cardiovascular Quality & Outcomes

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

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LBBB and heart failure—Relationships among QRS amplitude, duration, height, LV mass, and sex

Journal of Cardiovascular Electrophysiology

Relationships Among QRS Amplitude, Duration, Height, LV mass and Sex Abstract Background Height, left ventricular (LV) size, and sex were proposed as additional criteria for patient selection for cardiac resynchronization therapy (CRT) but their connections with the QRS complex in left bundle branch block (LBBB) are little investigated. We evaluated these.

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Sex Differences in the Association of Genome-Wide Systolic Blood Pressure Polygenic Risk Score With Hypertension

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Ahead of Print.