Dr. Smith's ECG Blog
FEBRUARY 16, 2024
Written by Pendell Meyers A teenager was playing basketball when he suddenly developed palpitations and lightheadedness. He presented soon afterward at the Emergency Department with ongoing symptoms. Mentation and blood pressure were normal. He had no chest pain or shortness of breath. Heart rates on the monitor fluctuated from 180-250 bpm. Here is his triage ECG: What do you think?
Med Page Today
FEBRUARY 16, 2024
(MedPage Today) -- NATIONAL HARBOR, Md. -- Moms who had hypertensive disorders of pregnancy (HDP) or gestational diabetes mellitus (GDM) were more likely to have kids with worse cardiovascular health (CVH) in adolescence, a secondary analysis.
HCPLive
FEBRUARY 16, 2024
A groundbreaking phase 1 study using CAR-T cells to treat severe lupus highlights a collaborative effort between the Cellular Therapy Program and rheumatology programs to pioneer innovative patient care.
Med Page Today
FEBRUARY 16, 2024
(MedPage Today) -- In people with mild to moderate hypertension taken off antihypertensive treatment, quarterly and biannual injections of novel RNA silencer zilebesiran showed promise for safely reducing systolic blood pressure (BP), the phase.
Science Daily - Heart Disease
FEBRUARY 16, 2024
The efficiency of oxygen supply to tissues is a factor in the severity of important diseases such as Covid-19 and heart conditions. Scientists already know that the relationship between the length of a person's index and ring fingers, known as the 2D:4D ratio is correlated with performance in distance running, age at heart attack and severity of Covid-19.
Medical Xpress - Cardiology
FEBRUARY 16, 2024
You may be familiar with high-density, or good cholesterol; low-density lipoproteins (LDL), or bad cholesterol; and their connections to heart health. But what about triglycerides? Often that word gets skimmed over when talking about cholesterol levels.
HCPLive
FEBRUARY 16, 2024
The approval is based upon phase 3 findings from the OUtMATCH study, representing the first treatment for adult and pediatric patients with accidental exposure to 1 or more food allergens.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HCPLive
FEBRUARY 16, 2024
Nearly 30% of patients were receiving potentially inappropriately prescribed medications at the start of the study and more than 20% were still receiving these medications 1 year later.
DAIC
FEBRUARY 16, 2024
mtaschetta-millane Fri, 02/16/2024 - 09:40 February 16, 2024 — Cardio Diagnostics Holdings, Inc. , an AI-driven precision cardiovascular medicine company, announced the nationwide rollout and a significant expansion of its groundbreaking HeartRisk platform. HeartRisk combines insights from HIPAA-compliant anonymized and aggregated clinical cardiovascular data obtained through Cardio Diagnostics’ Epi+Gen CHD and PrecisionCHD clinical tests, with industry and geographic data to enable real-time
HCPLive
FEBRUARY 16, 2024
In this interview, Bissonnette spoke on the significance of the recent topline data on JNJ-2113 for patients with plaque psoriasis.
Journal of the American Heart Association
FEBRUARY 16, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundMajor depressive disorder (MDD) has been identified as a causal risk factor for multiple forms of cardiovascular disease. Although observational evidence has linked MDD to peripheral artery disease (PAD), causal evidence of this relationship is lacking.Methods and ResultsInverse variance weighted 2‐sample Mendelian randomization was used to test the association the between genetic liability for MDD and genetic liability for PAD
HCPLive
FEBRUARY 16, 2024
Older adults who use a salt substitute had a 40% lower incidence of experiencing hypertension than people who use regular salt.
Journal of the American Heart Association
FEBRUARY 16, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundLittle is known about risks of hypertensive disorders of pregnancy in both first‐ and second‐generation immigrant women in Europe and other Western countries; such knowledge may help elucidate the influence of genetic versus social factors on such risks. We aimed to study both first‐ and second‐generation immigrant women for the presence of all types of hypertension (preexisting hypertension, gestational hypertension, preeclamp
HCPLive
FEBRUARY 16, 2024
Microalbuminuria and low body iron levels displayed a significant association with pediatric hearing loss independently.
Journal of the American Heart Association
FEBRUARY 16, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundInhibition of prostaglandin synthesis by nonsteroidal anti‐inflammatory drugs is associated with cardiovascular mortality and kidney disease. This study hypothesizes that urinary prostaglandin E2 (PGE2) and PGE2 metabolite (PGEM) excretions are markers of cardiovascular and kidney health, because they reflect both systemic and kidney‐derived PGE2 production.Methods and ResultsPGE2 and PGEM were measured in spot urine samples fr
Becker's Hospital Review - Cardiology
FEBRUARY 16, 2024
When patients awaiting crucial heart transplants are placed on the organ transplant waiting list, they've traditionally been arranged based on what type of treatments they were receiving for their current condition. But researchers from the University of Chicago have discovered a new, more accurate way to rank patients.
Frontiers in Cardiovascular Medicine
FEBRUARY 16, 2024
Objectives In postmenopausal states, women may not maintain blood pressure (BP) in the same way as men, even though most women follow their treatment plans and prescriptions more consistently than men. Biological and lifestyle factors influence the progression of hypertension in postmenopausal women (PMW). This study aimed to determine biosocial predictors associated with achieving the target BP in PMW with hypertension.
HCPLive
FEBRUARY 16, 2024
Nearly half (47%) of biosimilar users knew they were using biosimilars but 31% thought the medicine was an originator. In contrast, 80% of originator users knew they were using an originator, and none thought they were using a biosimilar.
American College of Cardiology
FEBRUARY 16, 2024
The following are key points to remember from an American Heart Association Scientific Statement on opportunities in the postpartum period to reduce cardiovascular disease (CVD) risk after adverse pregnancy outcomes.
HCPLive
FEBRUARY 16, 2024
Results confirmed the cost-effectiveness of Japan’s mandated school urinary screening strategy, also pointing to fewer patients progressing to ESKD compared to no screening.
Physiologically Speaking
FEBRUARY 16, 2024
Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Zeit Calendar , Examine.com , and my eBook, “VO2 Max Essentials ”, can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
HCPLive
FEBRUARY 16, 2024
Additional research on this form of moisturizer and other ingredients for acne with larger sample sizes may be needed to verify efficacy for acne vulgaris.
Journal of the American Heart Association
FEBRUARY 16, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundClinical outcome of ischemic cardiogenic shock (CS) requiring extracorporeal membrane oxygenation is highly variable, necessitating appropriate assessment of prognosis. However, a systemic predictive model estimating the mortality of refractory ischemic CS is lacking. The PRECISE (Prediction of In‐Hospital Mortality for Patients With Refractory Ischemic Cardiogenic Shock Requiring Veno‐Arterial Extracorporeal Membrane Oxygenati
HCPLive
FEBRUARY 16, 2024
Tom Nguyen, MD, discusses a recent study he led comparing outcomes of TAVR explantation based on transcatheter heart valve type.
Journal of the American Heart Association
FEBRUARY 16, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundPrior research suggests clinical effects of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) are mediated by changes in glycated hemoglobin, body weight, systolic blood pressure, hematocrit, and urine albumin‐creatinine ratio.
HCPLive
FEBRUARY 16, 2024
Older adults who use a salt substitute had a 40% lower incidence of experiencing hypertension than people who use regular salt.
Circulation
FEBRUARY 16, 2024
Circulation, Ahead of Print. BACKGROUND:Hypertrophic cardiomyopathy (HCM) is a common heritable myocardiopathy. Although HCM has been reported to be associated with many variants of genes involved in sarcomeric protein biomechanics, pathogenic genes have not been identified in patients with partial HCM. FARS2 (the mitochondrial phenylalanyl-tRNA synthetase), a type of mitochondrial aminoacyl-tRNA synthetase, plays a role in the mitochondrial translation machinery.
HCPLive
FEBRUARY 16, 2024
Over the study period, pain screening procedures were integrated within routine clinical visits and providers’ workflow in sickle cell disease care.
Hypertension Journal
FEBRUARY 16, 2024
Hypertension, Ahead of Print. The renin-angiotensin system is the most important peptide hormone system in the regulation of cardiovascular homeostasis. Its classical arm consists of the enzymes, renin, and angiotensin-converting enzyme, generating angiotensin II from angiotensinogen, which activates its AT1receptor, thereby increasing blood pressure, retaining salt and water, and inducing cardiovascular hypertrophy and fibrosis.
American College of Cardiology
FEBRUARY 16, 2024
In part 2 of this 2 part podcast, the ACC Cardiovascular (CV) Dyad Leadership Workgroup discusses how to utilize a CV dashboard to assess, communicate and optimize operations.
Hypertension Journal
FEBRUARY 16, 2024
Hypertension, Ahead of Print. BACKGROUND:The relationship between placental pathology and the maternal syndrome of preeclampsia is incompletely characterized. Mismatch between placental nutrient supply and fetal demands induces stress in the syncytiotrophoblast, the layer of placenta in direct contact with maternal blood. Such stress alters the content and increases the release of syncytiotrophoblast extracellular vesicles (STB-EVs) into the maternal circulation.
Circulation: Cardiovascular Quality & Outcomes
FEBRUARY 16, 2024
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.
Hypertension Journal
FEBRUARY 16, 2024
Hypertension, Ahead of Print. BACKGROUND:The zona glomerulosa of the adrenal gland is responsible for the synthesis and release of the mineralocorticoid aldosterone. This steroid hormone regulates salt reabsorption in the kidney and blood pressure. The most important stimuli of aldosterone synthesis are the serum concentrations of angiotensin II and potassium.
Science Daily - Heart Disease
FEBRUARY 16, 2024
Having a heart attack significantly increases the risk of developing other serious long-term health conditions, a major new study shows. Researchers analyzed more than 145 million records covering every adult patient admitted to hospital in England over a nine-year period to establish the risk of long-term health outcomes following a heart attack -- in the largest study of its kind.
Journal of the American Heart Association
FEBRUARY 16, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundResting coronary flow velocity (CFV) in the mid‐distal left anterior descending coronary artery can be easily assessed with transthoracic echocardiography. In this observational study, the authors sought to assess the relationship between resting CFV, CFV reserve (CFVR), and outcome in patients with chronic coronary syndromes.Methods and ResultsIn a prospective multicenter study design, the authors retrospectively analyzed 7576
Circulation: Cardiovascular Quality & Outcomes
FEBRUARY 16, 2024
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Background:Quasi-experimental methods (QEMs) are a family of techniques used to estimate causal relationships when randomized controlled trials are unfeasible or unethical. They offer a powerful alternative to observational studies by introducing random assignment of individuals or groups into their design, thereby offering stronger means of establishing causation.
Journal of the American Heart Association
FEBRUARY 16, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundLittle is known about hospital pricing for coronary artery bypass grafting (CABG). Using new price transparency data, we assessed variation in CABG prices across US hospitals and the association between higher prices and hospital characteristics, including quality of care.Methods and ResultsPrices for diagnosis related group code 236 were obtained from the Turquoise database and linked by Medicare Facility ID to publicly availa
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