Thu.Feb 08, 2024

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AI-based system to guide stroke treatment decisions may help prevent another stroke

American Heart News - Stroke News

Research Highlights: An artificial intelligence (AI) system to help guide treatment decisions for stroke patients led to improved stroke care quality and fewer recurrent strokes, heart attacks and vascular death among stroke survivors three months.

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Psychologically Distressed Patients Faced Challenges During COVID-19

HCPLive

According to a new study, overall outpatient mental health care increased from 11.2% to 12.4% between 2018 and 2018. However, for individuals with serious psychological distress, the rate of care decreased from 46.5% to 40.4%.

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Relationship between stress hyperglycaemic ratio and incidence of in-hospital cardiac arrest in patients with acute coronary syndrome: a retrospective cohort study

Cardiovascular Diabetology

The stress hyperglycaemic ratio (SHR), a new marker that reflects the true hyperglycaemic state of patients with acute coronary syndrome (ACS), is strongly associated with adverse clinical outcomes in these pa.

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Deepak Bhatt, MD, MPH: Need for In-Hospital Initiation, Uptitration of GDMT in Acute Heart Failure

HCPLive

Deepak Bhatt, MD, MPH, discusses the need to improve in-hospital initiation and uptitration of guideline-directed medical therapy in heart failure.

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International Stroke Conference Researcher Finds AI-based System Helped Guide Treatment, Lowered Stroke Recurrence

DAIC

Researchers presenting late-breaking science during the second day of the American Stroke Association’s International Stroke Conference, ISC 2024, reported they found an artificial intelligence (AI) system to help guide treatment decisions for stroke patients led to improved stroke care quality and fewer recurrent strokes, heart attacks and vascular death among stroke survivors three months after a stroke.

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Stephen Harrison, MD: Resmetirom Could Address 'Monumental' Unmet Need in NASH

HCPLive

Stephen Harrison, MD, provides insight into the use of resmetirom for NASH with fibrosis ahead of the thyroid hormone receptor-β selective agonist’s March 14 PDUFA date.

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American Heart Association Announces New Scientific Research Will Test PREVENT Risk Calculator Among Diverse Groups

DAIC

The American Heart Association (AHA) has announced it is providing $450,000 in grants to assess its new risk prediction tool among diverse race, age, geographic and socioeconomic groups. Research teams from Northwestern University Feinberg School of Medicine, New York University and Duke University will work together to assess the accuracy of the AHA’s new PREVENT risk calculator.

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Fast Stroke Thrombolysis Boosts Impact of Thrombectomy

Med Page Today

(MedPage Today) -- PHOENIX -- Sooner is better for intravenous thrombolysis (IVT) given before mechanical thrombectomy for acute ischemic stroke, a meta-analysis of patient-level data from randomized controlled trials showed. While the overall.

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Heart organoids simulate pregestational diabetes-induced congenital heart disease

Science Daily - Heart Disease

An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. The findings also showed that endoplasmic reticulum (ER) stress and lipid imbalance are critical factors contributing to these disorders, which could be ameliorated with exposure to omega-3s.

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Living with myocardial ischaemia and no obstructive coronary arteries: a qualitative study

Open Heart

Objective To explore the lived experience of people with myocardial ischaemia with no obstructive arteries. Design Qualitative study using semistructured interviews. Setting Telephone interviews with 17 participants living in the UK. Participants 17 people (2 males, 15 females; aged 31–69 years) with a presumed or confirmed diagnosis of myocardial ischaemia with no obstructive arteries, recruited via social media and online patient-led support forums.

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Dizziness Linked to Mortality Risk for Diabetes, Cardiovascular Disease, Cancer

HCPLive

A new study found balance and falling were linked to an increased risk of all-cause mortality, as well as cause-specific mortality from cardiovascular disease and diabetes.

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Simultaneous assessment of stress hyperglycemia ratio and glycemic variability to predict mortality in patients with coronary artery disease: a retrospective cohort study from the MIMIC-IV database

Cardiovascular Diabetology

Stress hyperglycemia and glycemic variability (GV) can reflect dramatic increases and acute fluctuations in blood glucose, which are associated with adverse cardiovascular events. This study aimed to explore w.

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Mechanical valve replacement for patients with rheumatic heart disease: the reality of INR control in Africa and beyond

Frontiers in Cardiovascular Medicine

The majority of patients requiring heart valve replacement in low- to middle-income countries (LMICs) need it for rheumatic heart disease (RHD). While the young age of such patients largely prescribes replacement with mechanical prostheses, reliable anticoagulation management is often unattainable under the prevailing socioeconomic circumstances. Cases of patients with clotted valves presenting for emergency surgery as a consequence of poor adherence to anticoagulation control are frequent.

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New Insight: Reengaging the Retina Community in 2024 with David Eichenbaum, MD and Roger Goldberg, MD

HCPLive

In a new episode of New Insight with Veeral Sheth, MD, a trio of retina specialists host a well-rounded conversation on recent conference news, the anniversary of a landmark agent, and what’s to come in 2024 for the specialty.

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Lumbar disc herniation is an independent predictor of plaque burden in the patients with unstable angina

Frontiers in Cardiovascular Medicine

Objective Assessing the impact of lumbar disc herniation (LDH) on the plaque burden of coronary atherosclerosis is our objective. Methods In this study, a total of 212 patients (age 46–80 years) with unstable angina (UA) who underwent coronary angiography (CAG) in our hospital from January 2018 to July 2022 due to UA were included. Patients were divided into LDH group ( n  = 106) and no LDH group ( n  = 106).

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James Palmer, MD: Reacting to New Findings on EDS-FLU for Chronic Rhinosinusitis

HCPLive

In this interview, Palmer shares several of the key findings and their implications for the future of this patient population.

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Simultaneous 18-FDG PET and MR imaging in lower extremity arterial disease

Frontiers in Cardiovascular Medicine

Background Simultaneous positron emission tomography (PET) and magnetic resonance imaging (MRI) is a novel hybrid imaging method integrating the advances of morphological tissue characterization of MRI with the pathophysiological insights of PET applications. Aim This study evaluated the use of simultaneous 18-FDG PET/MR imaging for characterizing atherosclerotic lesions in lower extremity arterial disease (LEAD).

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Akiko Iwasaki, PhD: Unraveling the Role of Endogenous Retroviruses in Lupus Autoimmunity

HCPLive

By establishing a link between endogenous retroviruses, inflammation, and autoreactive T cells in lupus, research conducted by Akiko Iwasaki, PhD, has the potential to pave the way for new targeted therapies for this complex condition.

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Left ventricular to left arial volume ratio in the assessment of filling pressure in patients with dyspnoea and preserved ejection fraction

Frontiers in Cardiovascular Medicine

Introduction Assessing filling pressure (FP) remains a clinical challenge despite advancements in non-invasive imaging techniques. This study investigates the utility of echocardiographic left ventricular (LV) to left atrial (LA) volume ratio in estimating the resting FP in patients with dyspnoea and preserved ejection fraction (EF). Methods This study is a prospective, single-centre analysis of 53 consecutive patients with dyspnoea (New York Heart Association grade 2 or 3) and LVEF of ≥50% (mea

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IHL-675A Reveals Promising Safety and Pharmacokinetic Profile, with Mark Bleackley, PhD

HCPLive

Results demonstrated IHL-675A was well-tolerated, with no concerning adverse events or serious adverse events reported.

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Florida community hospital to build $200M heart center

Becker's Hospital Review - Cardiology

Naples (Fla.) Community Hospital received approval from the city council to build its $200 million NCH Cardiac Institute.

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Circulating exosomal mir-16-2-3p is associated with coronary microvascular dysfunction in diabetes through regulating the fatty acid degradation of endothelial cells

Cardiovascular Diabetology

Coronary microvascular dysfunction (CMD) is a frequent complication of diabetes mellitus (DM) characterized by challenges in both diagnosis and intervention. Circulating levels of microRNAs are increasingly re.

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Mitral valve repair for degenerative mitral regurgitation with Carpentier’s functional classification type II in elderly patients: a single center experience

Journal of Cardiothoracic Surgery

Mitral valve (MV) repair for Carpentier functional classification Type II (C-II) mitral regurgitation (MR) is widely accepted because of its efficacy. It is unclear whether MV repair has the same benefits in e.

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Radial Access a Toss Up for Stroke Thrombectomy

Med Page Today

(MedPage Today) -- PHOENIX -- Transradial access for endovascular thrombectomy was noninferior to standard transfemoral access, a single-center randomized trial showed. The rate of recanalization success was 87.9% (51 of 58) with transfemoral.

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Pectoral muscle mass is not a robust prognostic factor for survival after left ventricular assist device (LVAD) implantation

Journal of Cardiothoracic Surgery

Left ventricular assist devices (LVAD) are an established treatment for end-stage left ventricular heart failure. Parameters are needed to identify the most appropriate patients for LVADs. This study aimed to.

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Exhibitor Prospectus - STS Workshop on Robotic Cardiac Surgery

Society of Thoracic Surgeons - Congenital

Exhibitor Prospectus - STS Workshop on Robotic Cardiac Surgery smccarthy Thu, 02/08/2024 - 14:34 Stand Out Among Your Competitors & Partners Increase your company’s opportunity for personalized interactivity with attendees by exhibiting at the Workshop. Several breaks will take place in the exhibit area and have been scheduled so that attendees have plenty of time to visit your booth.

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Corticosteroid Still Doesn't Help After Stroke in the Thrombectomy Era

Med Page Today

(MedPage Today) -- PHOENIX -- A short course of low-dose methylprednisolone added to endovascular thrombectomy after acute ischemic stroke did not improve outcomes overall, though there was a lower rate of mortality, the randomized MARVEL trial.

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Nephrology Month in Review: January 2024

HCPLive

Our January 2024 month-in-review spotlights some of our top coverage in nephrology, ranging from FDA news to clinical trial data and research about approaches to improving renal health.

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Adjunctive Thrombolysis Doesn't Boost tPA Benefits

Med Page Today

(MedPage Today) -- PHOENIX -- Adjunctive thrombolysis with either argatroban or eptifibatide for acute ischemic stroke did not boost efficacy and contributed to risk, the MOST trial showed. When given after starting alteplase (Activase) or tenecteplase.

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No Difference in Psoriasis Immune Response Despite Switch Between AVT02, Adalimumab

HCPLive

These data were found to be consistent with the findings in the main study, the contents of which suggested the treatments’ interchangeability.

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Clues to cancer drug's deadly side effects could make it safer

Science Daily - Heart Disease

For some leukemia patients, their only treatment option carries a risk of heart failure.

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National Variation in Hospital MTEER vs. TAVR Outcomes

American College of Cardiology

Is there a relationship between site-level volumes and outcomes for transcatheter aortic valve replacement (TAVR) and mitral transcatheter edge-to-edge repair (MTEER)?

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Clinical and Prognostic Implications of Right Ventricular Uptake on Bone Scintigraphy in Transthyretin Amyloid Cardiomyopathy

Circulation

Circulation, Ahead of Print. BACKGROUND:The extent of myocardial bone tracer uptake with technetium pyrophosphate, hydroxymethylene diphosphonate, and 3,3-diphosphono-1,2-propanodicarboxylate in transthyretin amyloid cardiomyopathy (ATTR-CM) might reflect cardiac amyloid burden and be associated with outcome.METHODS:Consecutive patients with ATTR-CM who underwent diagnostic bone tracer scintigraphy with acquisition of whole-body planar and cardiac single-photon emission computed tomography (SPEC

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E-Cigarettes vs. Varenicline and Nicotine Gum as Aid to Stop Smoking

American College of Cardiology

Are electronic cigarettes (ECs) efficaciously superior to nicotine replacement therapy (NRT) or noninferior to varenicline for smoking cessation?

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Phosphorylation-Regulated Dynamic Phase Separation of HIP-55 Protects Against Heart Failure

Circulation

Circulation, Ahead of Print. BACKGROUND:Heart failure (HF), which is the terminal stage of many cardiovascular diseases, is associated with low survival rates and a severe financial burden. The mechanisms, especially the molecular mechanism combined with new theories, underlying the pathogenesis of HF remain elusive. We demonstrate that phosphorylation-regulated dynamic liquid–liquid phase separation of HIP-55 (hematopoietic progenitor kinase 1–interacting protein of 55 kDa) protects against HF.

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Transcatheter Aortic Valve Implantation in a Patient With Anomalous Left Main Coronary Artery from Right Coronary Artery

The American Journal of Cardiology

Publication date: 15 March 2024 Source: The American Journal of Cardiology, Volume 215 Author(s): Sivakumar Sudhakaran, Parijat Joy, Alex Sbrocchi, Robert Hebeler, Robert Stoler

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Papillary fibroelastoma originating from the atrial septum touching the mitral valve leading to infective endocarditis: a case report

Journal of Cardiothoracic Surgery

Cardiac papillary fibroelastoma is a rare benign tumor, which is often mistaken for a vegetation. Predominantly asymptomatic, it can cause life-threatening complications. Although rare, mobile papillary fibroe.