Thu.Mar 14, 2024

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African American veterans with PTSD had higher risk of re-hospitalization after stroke

American Heart News - Heart News

Research Highlights: In a review of data for more than 90,000 veterans hospitalized with stroke, African American veterans who had been previously diagnosed with post-traumatic stress disorder (PTSD) were significantly more likely to be.

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Meth-Related Cardiomyopathy: Where the Biggest Clusters Are

Med Page Today

(MedPage Today) -- The American West has seen the biggest surge of cardiomyopathy-associated hospital admissions among methamphetamine users, based on 13 years of the latest available hospital admission data. The National Inpatient Sample (NIS.

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Small amounts of licorice raise blood pressure, study finds

Science Daily - Heart Disease

It is known that large amounts of licorice cause high blood pressure. A new study now shows that even small amounts of licorice raise blood pressure. The individuals who react most strongly also show signs of strain on the heart.

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Crisis Point: Stigma Hinders Adoption of Hepatitis C-Positive Donor Kidneys

HCPLive

To acknowledge World Kidney Day, our latest episode of Crisis Point focuses on the stigma surrounding the use of HCV-positive donor kidneys amid the ongoing organ shortage crisis, with the perspective of a pair of experts and an HCV donor kidney recipient.

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Three patients with chest pain and “normal” ECGs: which had OMI? Which were normal? And how did the Queen of Hearts perform?

Dr. Smith's ECG Blog

Written by Jesse McLaren Three patients presented with acute chest pain and ECGs that were labeled by the computer as completely normal, and which was confirmed by the final cardiology interpretation (which is blinded to patient outcome) also as completely normal. What do you think? Case 1: Case 2: Case 3: Triage ECGs labeled ‘normal’ There have been a number of small studies suggesting that triage ECGs labeled ‘normal’ are unlikely to have clinical significance, and therefore that emergency phy

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UCLA Health Selects Dr. Priscilla Hsue as Cardiology Division Chief

DAIC

The UCLA Department of Medicine has announced that Priscilla Hsue, MD will be joining as the chief of the Division of Cardiology at UCLA, effective July 1, 2024. Hsue will come to UCLA from UC San Francisco (UCSF), where she leads a portfolio of clinical and translational studies on HIV-related cardiovascular disease and Long COVID. She is currently serving as co-director of the UCSF Center for Excellence in Vascular Research, and is a member of ImmunoX and the Cardiovascular Research Institute.

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Resmetirom (Rezdiffra) Receives Historic FDA Approval for Noncirrhotic NASH

HCPLive

In a landmark decision, the FDA has granted accelerated approval to resmetirom (Rezdiffra) for noncirrhotic NASH with moderate to advanced fibrosis.

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A Voice Detecting Depression? Lindsey Venesky, PhD, Discusses New Data

HCPLive

Lindsey Venesky, PhD, discussed how a mental fitness vocal biomarker tool could identify mental health symptoms people might not even be aware of through their voice.

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Artificial intelligence predicts undiagnosed atrial fibrillation in patients with embolic stroke of undetermined source using sinus rhythm electrocardiograms

HeartRhythm

Artificial intelligence (AI)-enabled sinus rhythm (SR) electrocardiogram (ECG) interpretation can aid in identifying undiagnosed paroxysmal atrial fibrillation (AF) in patients with embolic stroke of undetermined source (ESUS).

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Addressing HS Risks at the Genetic Level, with Kai Li, BSc

HCPLive

Data show significant maternal and fetal risks in cases when pregnant women are diagnosed with hidradenitis suppurativa. A researcher discusses opportunities to learn more.

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A contemporary training concept in critical care cardiology

Frontiers in Cardiovascular Medicine

Critical care cardiology (CCC) in the modern era is shaped by a multitude of innovative treatment options and an increasingly complex, ageing patient population. Generating high-quality evidence for novel interventions and devices in an intensive care setting is exceptionally challenging. As a result, formulating the best possible therapeutic approach continues to rely predominantly on expert opinion and local standard operating procedures.

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Izokibep Data from Psoriatic Arthritis, Hidradenitis Suppurativa Support Phase 3 Development

HCPLive

On March 11, 2024, Acelyrin Inc. announced new positive data from clinical trial programs examining their IL-17A inhibitor izokibep in patients psoriatic arthritis and hidradenitis suppurativa.

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Exercise Benefits Gained Faster By Women Than Men, With Greater Overall Benefit

American College of Cardiology

Women not only receive greater health benefits than men from exercise but they receive the same benefits as men in nearly half the time, and for the same volume of exercise they have a lower risk of premature death, according to the results of a study published Feb. 19 in JACC.

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Case Report: Combined perioperative extracorporeal membrane oxygenation for acute heart failure caused by mitral regurgitation

Frontiers in Cardiovascular Medicine

Extracorporeal membrane oxygenation (ECMO) and extracorporeal life support (ECLS) devices are well-established adjunctive treatment measures for patients with heart failure. ECMO can serve as a bridge to transplant in a chronic setting or as a salvage therapy for patients who are unable to be weaned from bypass following cardiac surgery. However, the role of ECMO as a bridge to definitive therapy in a setting of acute heart failure is less established.

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ECLIPSE: Blood-Based Test Shows 83% Accuracy for Detecting Colorectal Cancer

HCPLive

Results showed the cell-free DNA blood-based test had 83% sensitivity for colorectal cancer, 90% specificity for advanced neoplasia, and 13% sensitivity for advanced precancerous lesions.

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DECIDE-Salt: Salt Substitutes May Help Maintain Healthy BP in Older Adults

American College of Cardiology

Replacing regular salt with a salt substitute in the kitchens of elderly care facilities in China reduced the incidence of hypertension without increasing episodes of hypotension among older Chinese adults with normal blood pressure (BP), according to a post hoc analysis of the DECIDE-Salt study published Feb. 12 in JACC.

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Andrew F. Alexis, MD, MPH: Discussing Controversies in Acne, Rosacea

HCPLive

A post-AAD 2024 discussion on the importance of tailoring acne and rosacea management to individual patients’ needs, focusing more attention on diverse skin types and backgrounds.

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Case Report: Comprehensive evaluation of ECG phenotypes and genotypes in a family with Brugada syndrome carrying SCN5A-R376H

Frontiers in Cardiovascular Medicine

Background Brugada syndrome (BrS) is a channelopathy that can lead to sudden cardiac death in the absence of structural heart disease. Patients with BrS can be asymptomatic or present with symptoms secondary to polymorphic ventricular tachycardia or ventricular fibrillation. Even though BrS can exhibit autosomal dominant inheritance, it is not easy to identify the phenotype and genotype in a family thoroughly.

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Nesvategrast for Diabetic Retinopathy Misses Primary Endpoint in Phase 2 Trial

HCPLive

Nesvategrast was safe and well tolerated but did not exhibit a statistically significant impact on the severity or progression of diabetic retinopathy in the phase 2 DR:EAM trial.

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Best practices for vascular arterial access and closure: a contemporary guide for the cardiac catheterization laboratory

Frontiers in Cardiovascular Medicine

More than 1 million transcatheter-based cardiovascular procedures across the spectrum of interventional cardiology are performed annually in the United States. With the expanded indications for and increased complexities associated with these procedures, interventional cardiologists are expected to possess the requisite expertise to complete these interventions safely and effectively.

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Having Therapy for Anxiety Before the Pandemic Prevented Uptick in Symptoms After

HCPLive

“Having a previous anxiety disorder before a crisis occurs can be a blessing” — a new study found therapy for anxiety before the COVID-19 pandemic helped individuals not have increased anxiety during and after the pandemic.

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Severe Prenatal Maternal Grief May Be Associated With Increased Risk of HF in Child

American College of Cardiology

Severe grief for a close family member experienced by a woman shortly before or during pregnancy was found to be associated with a later diagnosis of heart failure (HF) in a child through middle age, according to a study published on Feb. 21 in JACC: Heart Failure.

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Christopher Bunick, MD, PhD: Efficacy, Safety of TMB-001 in Treating Congenital Ichthyosis

HCPLive

In this AAD 2024 interview, Bunick highlights several new findings on the use of topical isotretinoin for treatment of congenital ichthyosis.

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Thoracoscopic McKeown esophagectomy in a patient with an azygos lobe

Journal of Cardiothoracic Surgery

The azygos lobe is a relatively rare anatomical variation, and there have been no reports, until date, of thoracoscopic McKeown esophagectomy for esophageal cancer in a patient with an azygos lobe. The azygos.

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Oral Minocycline Fails to Slow Enlargement of Geographic Atrophy

HCPLive

Oral minocycline was not associated with a decrease in GA enlargement over 24 months, compared with the run-in phase, in a recent phase 2 nonrandomized trial.

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Fixation devices made of poly-L-lactide composite for rib reconstruction after thoracotomy

Journal of Cardiothoracic Surgery

GRAND FIX mesh-type plates and pins (Gunze, Kyoto, Japan) are thin, bioabsorbable fixation devices made of poly-L-lactide (PLLA) composite. These devices are new, and how best to use them in clinical practice.

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Imaging cAMP nanodomains in human iPSC-derived cardiomyocytes

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 15 March 2024; doi:10.1038/s41569-024-01013-1 In this Tools of the Trade article, Charrière describes the FluoStep FRET-based biosensor used for high-resolution imaging of cAMP nanodomains that are involved in intracellular signalling in cardiomyocytes.

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Huge mediastinal ancient schwannoma causing acute respiratory failure: a case report

Journal of Cardiothoracic Surgery

Benign mediastinal tumor is usually asymptomatic and exhibits uncomplicated clinical course. Posterior mediastinal schwannoma is common, but a huge benign tumor causing acute respiratory failure due to mass ef.

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Personalizing Dry Eye Disease Management

HCPLive

Experts discuss the management of dry eye using conventional and new pharmacological treatments, as well as strategies for tailoring treatment approaches to individual patient characteristics.

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A case report of drug interaction between co-packaged nirmatrelvir-ritonavir and tacrolimus causing hyponatremia in a lung transplant recipient

Journal of Cardiothoracic Surgery

Coronavirus disease 2019 (COVID-19) infection in lung transplant recipients can be lethal owing to the use of immunosuppressants. Antiviral agents may be administered to these patients. Co-packaged nirmatrelvi.

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Emory completes $87.7M heart center expansion

Becker's Hospital Review - Cardiology

Emory University Hospital completes $87.7 million expansion for advanced cardiovascular care, including new ICU, operating rooms, and labs.

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Evaluation of intramural hematoma: a novel use of 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging

Journal of Cardiothoracic Surgery

Aortic intramural hematoma (IMH) is one of the typical entities of acute aortic syndrome and probably accounts for 5–25% of all cases. The ulcer-like projections (ULP), which are described as a focal, blood-fi.

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Post-Inflammatory Dyspigmentation in Patients With Skin of Color

HCPLive

Dr Linda Stein Gold and Dr Mona Shahriari discuss post-inflammatory dyspigmentation in patients with skin of color and its impact on patient’s quality of life.

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When Are Direct-Acting Oral Anticoagulants Not the Standard of Care?

NEJM Journal Watch - Cardiology

In a unique review, experts discuss conditions for which warfarin or antiplatelet drugs are preferable to DOACs and conditions for which DOAC safety and efficacy is uncertain.

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AHN Studying an Innovation that Improves Quality of Life and Cardiac Function in Heart Failure Patients

HCPLive

The AccuCinch® System, utilized by Allegheny General Hospital, offers a breakthrough approach to treating heart failure by targeting the left ventricle.

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Cardiopulmonary Exercise Testing in Evaluating ATTR Amyloidosis

American College of Cardiology

What are the functional phenotypes in patients with transthyretin (ATTR) amyloidosis, how is it associated with amyloid burden, and is there an association between functional status and prognosis?

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Communicating With Patients With Psoriasis With Skin of Color

HCPLive

2 expert dermatologists provide tips for communicating, in a culturally sensitive manner, with patients with skin of color.

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