Tue.Dec 26, 2023

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Young-Onset Dementia Tied to New Risk Factors

Med Page Today

(MedPage Today) -- Four new risk factors for young-onset dementia were identified in the prospective U.K. Biobank study. Orthostatic hypotension, vitamin D deficiency, high C-reactive protein (CRP) levels, and social isolation emerged as new risk.

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Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission

JAMA Cardiology

This secondary analysis of the Safety, Tolerability, and Efficacy of Rapid Optimization, Helped by N-Terminal Pro–Brain Natriuretic Peptide Testing of Heart Failure Therapies (STRONG-HF) randomized clinical trial investigates what variables are associated with success in uptitration of guideline-directed medical therapy after hospital discharge for an acute heart failure admission.

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Food as Diabetes Medicine? Maybe Not, Trial Suggests

Med Page Today

(MedPage Today) -- An intensive food-as-medicine program didn't improve glycemic control in adults with type 2 diabetes any better than usual care in a randomized clinical trial. After 6 months, both groups had a similar drop in HbA1c -- 1.5.

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Stacie Bell, PhD: The Effect of Cognitive Impairment on Daily Life in Patients with SLE

HCPLive

Stacie Bell, PhD, emphasizes the importance of collaborative or multidisciplinary care in patients with SLE.

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Nuclear Tracer Shortage; Weighing Post-Ablation OAC; Fix for Biased AI Tools?

Med Page Today

(MedPage Today) -- Magnesium's hemostatic effects in intracerebral hemorrhage were supported by reduced hematoma expansion in FAST-MAG participants who achieved higher serum magnesium levels with magnesium treatment. (Stroke) The American Society.

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5 Health Metrics To Consider In The New Year

Dr. Paddy Barrett

New Year. New You. At this time every year, billions of people likely begin their health journey. Rather than just aiming to get ‘Healthy’ this year, how about setting clear targets for improvement that are highly correlated to positive health outcomes? Here are five powerful metrics you can assess in the New Year to see where you stack up and where you might need to make some improvements.

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An elderly patient with stuttering chest pain. Don't jump to conclusions.

Dr. Smith's ECG Blog

I was reading ECGs on the system and saw this one, and instantly knew the probable ECG diagnosis: What do you think? I went to the patient's chart: Elderly woman with stuttering chest pain and SOB, and dizziness. What do you think now? This is a very typical ECG for Hypertrophic Cardiomyopathy. I sent it to our EKG Nerdz group and Jesse McLaren replied: "Apical HOCM" It reminded me of many other cases I have seen, such as this one: Left Bundle Branch Block with Less Than 1 mm of Concordant ST El

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MindMics Demonstrates Its In-ear Infrasonic Earbud Technology Shows Promise in Detection of Aortic Stenosis and Hearing Heart Murmurs

DAIC

milla1cf Tue, 12/26/2023 - 21:36 December 26, 2023 — MindMics, Inc. reported results from a clinical study of revolutionary earbuds that use a new technology - In-ear Infrasonic Hemodynography to Detects Aortic Stenosis Murmur Before and After Transcatheter Aortic Valve Replacement (TAVR). These results were published by Journal of the American College of Cardiology ( JACC): Case Reports Volume 28, Part 1 , 20 December 2023, 102089: [link] Results from an ongoing prospective clinical study c

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Study Finds Private Equity Takeovers Increase Adverse Event, Infection Rates at Hospitals

HCPLive

Study raises concerns about quality of care in the future, as results reveal private equity takeovers of hospitals associated with increased hospital-acquired adverse events, including falls and infections.

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Harlan M. Krumholz Named Editor-in-Chief of the Journal of the American College of Cardiology

DAIC

Harlan M. Krumholz, MD, SM, FACC milla1cf Tue, 12/26/2023 - 21:45 December 26, 2023 — Globally esteemed cardiologist and researcher, Harlan M. Krumholz, MD, SM, FACC , has been named editor-in-chief of the Journal of the American College of Cardiology , the nation’s leading source of clinical research in the field of cardiovascular medicine and the flagship journal of the American College of Cardiology.

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Implementation of the European Society of Cardiology 0/3-hour accelerated diagnostic protocol, using high sensitive troponin T: a clinical practice evaluation of safety and effectiveness involving 3003 patients with suspected acute coronary syndrome

Open Heart

Background There have been relatively few studies detailing the real-world effectiveness and safety of accelerated diagnostic protocols (ADP), using high sensitivity cardiac troponin (hs-cTn). Objective To analyse the safety and effectiveness of early emergency department (ED) discharge following implementation of the European Society of Cardiology (ESC) 0/3-hour ADP for suspected acute coronary syndromes (ACS).

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Keeping A Watchful Eye: Safety Reports in Geographic Atrophy Landscape

HCPLive

A headline year for retina disease drug development concurrently brought about research and discussion into the safety outcomes of these new agents.

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Transvenous lead extraction safety and efficacy in infected and non-infected patients using mechanical-only tools, prospective registry from a high-volume center

HeartRhythm

Transvenous lead extraction (TLE) is a well-established treatment option for patients with cardiac implantable electronic devices (CIED) complications.

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Effect of Flecainide and Ibutilide Alone and in Combination to Terminate and Prevent Recurrence of Atrial Fibrillation

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:There is a need for improved approaches to rhythm control therapy of atrial fibrillation (AF).METHODS:The effectiveness of flecainide (1.5 µmol/L) and ibutilide (20 nmol/L), alone and in combination, to cardiovert and prevent AF recurrence was studied in canine-isolated coronary–perfused right atrioventricular preparations.

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Prognostic impact of atrial cardiomyopathy: Long-term follow-up of patients with and without low-voltage areas following atrial fibrillation ablation

HeartRhythm

Atrial cardiomyopathy is known as an underlying pathophysiological factor in the majority of AF patients. Left atrial low-voltage areas (LVAs) are reported to coincide with fibrosis, and to likely represent atrial cardiomyopathy.

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Catalysts of cardiovascular electromechanical harmony? Unveiling the impact of RAS Inhibitors and ARNI on atrial fibrillation recurrence after ablation

Journal of Cardiovascular Pharmacology

An abstract is unavailable. This article is available as a PDF only.

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STRONG-HF Evidence for Proactive, Patient-Centered Prescribing

JAMA Cardiology

Perfection is not attainable, but if we chase perfection we can catch excellence.

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Case of Biopsy-Proven Wild-Type ATTR Cardiac Amyloidosis With Abnormal CMR and Negative 99mTc-HDP and PYP Nuclear Scintigraphy

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Ahead of Print.

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Pulse Biosciences Announces First-in-Human Procedures with its Novel CellFX Nanosecond Pulsed Field Ablation (nsPFA) Cardiac Catheter

DAIC

milla1cf Tue, 12/26/2023 - 21:19 December 26, 2023 — Pulse Biosciences, Inc. , a company primarily focused on leveraging its novel and proprietary CellFX Nanosecond Pulsed Field Ablation (nsPFA) technology for the treatment of atrial fibrillation, announced the completion of the first five procedures in its first-in-human feasibility study with its novel CellFX nsPFA cardiac catheter.

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Differences in treatment and clinical outcomes in patients aged >=75 years compared with those aged <=74 years following acute coronary syndromes: a prospective multicentre study

Open Heart

Objective This study describes the differences in treatment and clinical outcomes in patients aged ≥75 years compared with those aged ≤74 years presenting with acute coronary syndrome (ACS) and undergoing invasive management. Methods A large-scale cohort study of patients with ST-elevation/non-ST-elevation myocardial infarction (MI)/unstable angina underwent coronary angiography (January 2015–December 2019).