Tue.Jan 07, 2025

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Coffee Drinking Tied to Better Survival, but Timing Matters

Med Page Today

(MedPage Today) -- Any presumed health benefits of coffee may be limited to morning cups of joe, according to an observational study based on the National Health and Nutrition Examination Survey (NHANES). Compared with non-coffee drinkers, those.

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Vitamin D Deficiency Linked to Migraine Prevalence with Negative Correlation

HCPLive

Participants with greater vitamin D levels had a 16% lower migraine prevalence than those with lower vitamin D levels.

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Study challenges traditional risk factors for brain health in the oldest-old

Science Daily - Heart Disease

A study has found cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, not to be associated with an increased risk of such harm in individuals 90 and older.

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Intensive Blood Pressure Targets Could Benefit Clinical CKD Populations, Study Finds

HCPLive

Study findings suggest outcomes observed with intensive blood pressure targets in SPRINT are transportable to patients with CKD in clinical practice.

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Online QT calculator for wide QRS (LBBB, RBBB, etc.)

Dr. Smith's ECG Blog

(This was created by Arron Pearce ( [link] ) Online QT calculator for wide QRS (LBBB, RBBB, etc.

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Cannabinoid-Based Formula Demonstrates Proof-of-Concept for Treating RA

HCPLive

Despite improvements in PROs and disease activity, no statistically significant changes have been seen on blood biomarker analysis.

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Morning coffee may protect the heart better than all-day coffee drinking

Science Daily - Heart Disease

People who drink coffee in the morning have a lower risk of dying from cardiovascular disease and a lower overall mortality risk compared to all-day coffee drinkers, according to new research.

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Cell-based therapy improves outcomes in a pig model of heart attacks

Science Daily - Heart Disease

In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that overexpress cyclin D2 and are knocked out for human leukocyte antigen classes I and II. This research used a pig model of heart attacks.

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Fire1 System Receives FDA Breakthrough Device Designation

DAIC

tim.hodson Tue, 01/07/2025 - 10:01 Jan. 7, 2025 FIRE1 recently announced it has received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA) and has been accepted into the FDAs Total Product Lifecycle Advisory Program (TAP). FIRE1s Norm heart failure management system offers a unique approach for patients to manage heart failure.

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Cardiovascular Imaging in Pregnancy

American College of Cardiology

The prevalence of cardiovascular disease in pregnant people is estimated to be 1-4%, and this is expected to increase.

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Serum Uric Acid Levels Linked to Risk of Dyslipidemia in Type 2 Diabetes

HCPLive

Hyperuricemia was significantly linked to dyslipidemia and hypertriglyceridemia in hospitalized patients with type 2 diabetes, which remained after adjustment.

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CVD Toll From Sugary Drinks; Migraine Tx and Heart Risk; Baby Heart Xenotransplant?

Med Page Today

(MedPage Today) -- An estimated 2.2 million new cases of type 2 diabetes and 1.2 million new cases of cardiovascular disease (CVD) each year around the world were attributed to sugar-sweetened beverages. (Nature Medicine) With dropping temperatures.

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ApoB Levels Reveal Notable Heterogeneity by Hispanic, Latino Background

HCPLive

Variations in apoB concentration among Hispanic or Latino populations could provide important implications for apoB use in cardiovascular risk assessment.

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Computed tomography-guided microwave ablation therapy for pediatric adrenal neuroblastoma with lung nodule a case report

Journal of Cardiothoracic Surgery

Solid lung lesions are common in clinical practice, and percutaneous thermal ablation has been shown to be an effective treatment for these lesions. While computed tomography (CT)-guided microwave ablation (MW.

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Rheumatology Month in Review: December 2024

HCPLive

The rheumatology month in review emphasizes new research in PsA and on cardiovascular events in rheumatic disease.

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Aortic lumen repair with glue-felt technique before proximal anastomosis in acute type a aortic dissection surgery

Journal of Cardiothoracic Surgery

Despite the advances in medicine, aortic dissection remains a cardiac surgery emergency with high mortality and morbidity rates. This study examined the effects of the Glue+Felt technique, which uses biologi.

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Prior Use of Biologics, Adalimumab Help Predict HS Biologic Treatment Intensification

HCPLive

In this analysis, a retrospective and multi-center study was conducted to determine any predictors of biological therapy intensification in individuals with HS.

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Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study

Cardiovascular Diabetology

Remnant cholesterol (remnant-C) contributes to atherosclerotic cardiovascular disease (ASCVD), particularly in individuals with impaired glucose metabolism. Patients with impaired glu.

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Study Identifies Antibodies Linked to PSC Disease Severity, Transplant-Free Survival

HCPLive

Findings suggest the potential value of anti-gliadin and anti-F-actin IgA for risk stratification in patients with primary sclerosing cholangitis.

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Digital heart replicas find dangerous abnormalities: 3 study notes

Becker's Hospital Review - Cardiology

Computer-generated heart replicas, or twins, can be used to identify hidden abnormalities in patients with a dangerous heart rhythm disorder, according to a study published Jan. 6 in Circulation.

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Aflibercept Biosimilar Demonstrates Therapeutic Equivalence for DME

HCPLive

CT-P42 may help improve access to aflibercept in lower-income countries.

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Compensation, utilization keep rising for cardio APPs: 10 takeaways

Becker's Hospital Review - Cardiology

Advanced practice provider compensation has continued to increase year over year, according to 2023 data reported by the American College of Cardiology's consulting firm, MedAxiom.

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Intimate Partner Violence Linked to Lower Psychosocial Well-Being in Women, Not Men

HCPLive

A study found intimate partner violence significantly lowers women's psychosocial well-being across finances, health, and relationships, but not men's.

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In Memoriam: James N. Kirkpatrick, MD, FACC

American College of Cardiology

James N. Kirkpatrick, MD, FACC, a leader in echocardiography, a gifted mentor and teacher, and a pioneer in the field of medical ethics, passed away unexpectedly on Jan. 1.

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Enhancing Neuron Activity Promotes Functional Recovery by Inhibiting Microglia-Mediated Synapse Elimination After Stroke

Stroke Journal

Stroke, Ahead of Print. BACKGROUND:Activating glutamatergic neurons in the ipsilesional motor cortex can promote functional recovery after stroke. However, the underlying molecular mechanisms remain unclear. Clarifying key molecular mechanisms involved in recovery could help understand the development of neuromodulation strategies after stroke.METHODS:Adeno-associated virus 2/9-CamKIIa-hM3Dq-mCherry was injected into ipsilesional motor cortex by stereotaxic in the photothrombotic stroke model.

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Long-term changes in frailty and incident atrial fibrillation, heart failure, coronary heart disease, and stroke: A prospective follow-up study

HeartRhythm

People with frailty have increased prevalence and incidence of atrial fibrillation (AF).

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ACCEL Lite: Geographic Disparities in Access to Cardiologists in the United States

American College of Cardiology

Nearly one-half of US counties have no practicing cardiologists. These counties with limited access to cardiovascular care tend to be more rural and socioeconomically disadvantaged, with a greater burden of cardiovascular disease, highlighting deep geographic disparity in access to cardiovascular care in the US.

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Trans-baffle or Retrograde Aortic Approach for Atrial Arrhythmias Ablation in Patients with D-Transposition of the Great Arteries Palliated with Atrial Switch.

HeartRhythm

Patients with D-transposition of the great arteries (D-TGA) palliated with atrial switch often develop atrial arrhythmias (AA) requiring pulmonary venous atrium (PVA) access for ablation, which can be achieved via retrograde aortic approach (RAA) or trans-baffle access (TBA).13 Although both techniques are used in clinical practice, insufficient data exist to determine their relative advantages, prompting this study to compare their feasibility, safety, and outcomes.

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Second Year In Review, Third Year In Preview, and the 2024 JAHA Top 10

Journal of the American Heart Association

Journal of the American Heart Association, Volume 14, Issue 1 , January 7, 2025.

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Finding the Arrhythmic Needle in the Low-Risk Haystack: Heritability of Imaging Features of Arrhythmic Mitral Valve Prolapse

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Ahead of Print.

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Multiple Biomarkers to Predict Major Adverse Cardiovascular Events in Patients With Coronary Chronic Total Occlusions

The American Journal of Cardiology

Publication date: Available online 6 January 2025 Source: The American Journal of Cardiology Author(s): Srikanth Adusumalli, Cian P. McCarthy, Craig A. Magaret, Rhonda F. Rhyne, Farouc A. Jaffer, James L.

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Contemporary Approach to Cardiac Allograft Vasculopathy Surveillance: The Role of Coronary CT Angiography

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Ahead of Print.

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Elevated Plasma Nitrate Levels in Patients with Acute Coronary Syndrome

The American Journal of Cardiology

Publication date: Available online 6 January 2025 Source: The American Journal of Cardiology Author(s): C Venkata S Ram, Ferid Murad, A Sreenivas Kumar, Baby Shalini Muppalla, Asma Niloufer, Praveen Gajjela, Gokul Reddy Mandala, Ramakrishna Janapati, Sanjeeva Kumar E

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Inheritance of Imaging Parameters of Arrhythmic Risk in Mitral Valve Prolapse: A Pedigree Study

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:A subset of patients with mitral valve prolapse (MVP), a highly heritable condition, experience sudden cardiac arrest (SCA) or sudden cardiac death (SCD). However, the inheritance of phenotypic imaging features of arrhythmic MVP remains unknown.METHODS:We recruited 23 MVP probands, including 9 with SCA/SCD and 14 with frequent/complex ventricular ectopy.

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Ep 201 How EM Experts Think Part 2: Data Gathering, Diagnostic and Treatment Decision Making, Test Ordering and Interpretation, Documentation, Emotional Resilience

ECG Cases

In this Part 2 of our 2-part podcast series on How EM Experts Think with Dr. Reuben Strayer, Dr. Mike Betzner and Dr. Scott Weingart we dive deep into the nuances of practicing smarter, faster, and better in the ED. We answer questions like: How should we employ hypothetico-deductive reasoning in our daily practice of Emergency Medicine? How can we best streamline thorough data gathering for each case so that we don't miss key data points?

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Current Real‐World Status of Off‐Label Under‐ and Over‐Dose of Direct Oral Anticoagulants After Atrial Fibrillation Ablation

Journal of Cardiovascular Electrophysiology

Real-world ablation therapy with anticoagulants in management of atrial fibrillation for up to 1 year in Japan. DOAC, direct oral anticoagulant. ABSTRACT Background Off-label under- and overdosing of direct oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) is not uncommon in real-world practice. Objective This study aimed to identify efficacy and safety of off-label DOACs dose after AF ablation.

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The EM Expert Mindset – A Female Perspective

ECG Cases

Dr. Patricia Lee is an EM physician in Calgary, Alberta and an Assistant Professor at the University of Calgary in the Department of Emergency Medicine. She reached out to me after listening to Episode 200 How EM Experts Think Part 1 as a longtime supporter of EM Cases, to highlight the importance of recognizing challenges that female-identifying EM physicians may face before, during and after ED shifts.

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