Thu.Feb 20, 2025

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Clinical Considerations for Competitive Sports Participation for Athletes With Cardiovascular Abnormalities: A Scientific Statement From the American Heart Association and American College of Cardiology

Circulation

Circulation, Ahead of Print. This American Heart Association/American College of Cardiology scientific statement on clinical considerations for competitive sports participation for athletes with cardiovascular abnormalities or diseases is organized into 11 distinct sections focused on sports-specific topics or disease processes that are relevant when considering the potential risks of adverse cardiovascular events, including sudden cardiac arrest, during competitive sports participation.

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Perceptions and experiences of healthcare professionals in implementing an ERAS protocol for minimally invasive heart valve surgery: a qualitative analysis

Frontiers in Cardiovascular Medicine

IntroductionERAS protocols have revolutionized perioperative care by optimizing patient outcomes after major surgeries. Despite widespread recognition in various surgical specialties, the implementation of ERAS in cardiac surgery remains relatively novel.MethodsThis qualitative study employed semi-structured interviews to explore the perspectives and experiences of healthcare professionals involved in ERAS implementation, focusing on identifying facilitators and barriers.

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Fast Degradation of MecciRNAs by SUPV3L1/ELAC2 Provides a Novel Opportunity to Tackle Heart Failure With Exogenous MecciRNA

Circulation

Circulation, Ahead of Print. BACKGROUND:Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells. Mitochondria-encoded circular RNAs (mecciRNAs) are attracting more attention, and several members of mecciRNAs have already been recognized in regulating mitochondrial functions. Mitochondria dysfunctions are well-known to participate in heart failure (HF).

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Exercise can restore STAT3 levels in the amygdala, preventing stress-induced high blood pressure

Medical Xpress - Cardiology

Hypertension (high blood pressure) is a debilitating condition and a major cause of premature death worldwide. Chronic stress plays a significantrole, but the underlying mechanism involving biochemical pathways by which stress leads to hypertension has not been well understood. Understanding these pathways could lead to the development of therapeutic agents to combat hypertension.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Pediatric Atopic Dermatitis Most Effectively Treated with Upadacitinib, Study Finds

HCPLive

These data were the result of a new network meta-analysis looking specifically at children with eczema, highlighting the hierarchy of effectiveness among systemic drugs.

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How the brain rewires itself for language recovery after a stroke

Medical Xpress - Cardiology

A new study shows how the brain reorganizes itself in the first few months after a stroke to improve the ability to speak again. The findings will help researchers understand how functional networks work in the brain. They also have the potential to be used in the future for personalized treatment of stroke patients.

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Hidden genetic causes of congenital heart disease identified

Medical Xpress - Cardiology

Scientists at the Icahn School of Medicine at Mount Sinai and collaborators have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect.

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Semaglutide Tied to Small Risk of Potentially Blinding Eye Condition

Med Page Today

(MedPage Today) -- The use of semaglutide (Ozempic) was tied to a small risk of nonarteritic anterior ischemic optic neuropathy (NAION) in adults with type 2 diabetes, according to a retrospective study. In this review of 37.1 million patients.

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Study yields unexpected results from empagliflozin after heart attack

Medical Xpress - Cardiology

A new study, authored by KBH Professor Jan Inge Henter and published in the New England Journal of Medicine, has investigated whether the drug empagliflozin can reduce the risk of heart failure and death in patients who have recently suffered a heart attack.

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Cancer Diagnoses Cluster in Bleeders on Anticoagulation Therapy

Med Page Today

(MedPage Today) -- Cancer diagnoses tended to arise more in patients who bled on oral anticoagulants (OACs), a Canadian population-based cohort study found. In Ontario, people with atrial fibrillation (Afib) on OAC therapy had a 21.8% incidence.

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People with certain heart conditions may play competitive sports, scientific statement suggests

Science Daily - Heart Disease

Shared decision-making between clinicians and athletes of all ages who have cardiovascular abnormalities and want to participate in competitive sports is essential, according to a new joint scientific statement.

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Second Trimester Kidney Function Linked to Adverse Pregnancy Outcomes

HCPLive

Low and high second-trimester eGFR values were linked to adverse pregnancy outcomes, including preeclampsia, preterm birth, low birth weight, and fetal loss.

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HCN4 in the atrioventricular node

HeartRhythm

The hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) drives the funny current (If) in cardiac pacemaker regions. Its involvement in sinoatrial node pacemaker generation is well-known, but its function in the atrioventricular (AV) node (AVN) has not intensively been studied. HCN4 is expressed in the AVN and its expression within the AVN seems similar across mammalian species with HCN4 presence in the inferior nodal extensions, compact node, and atrioventricular bundle.

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FDA Clears IND Application for Zabalafin Hydrogel Treatment of Atopic Dermatitis

HCPLive

Alpyns Investigational New Drug applications clearance by the FDA for the new Zabalafin Hydrogel for atopic dermatitis follows positive phase 2a clinical findings.

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New Guidance Addresses Competitive Sports Participation For Athletes With CV Abnormalities

American College of Cardiology

A new joint Scientific Statement from the American Heart Association (AHA) and the ACC provides new and updated clinical guidance on how to assess risk when considering competitive sports participation for people with various cardiovascular conditions.

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Multidisciplinary Care Model Improves Liver, Metabolic Outcomes in MASH

HCPLive

The multidisciplinary care model included 7 co-located specialists who aided patient education, lifestyle intervention, and drug therapy strategies for MASH.

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How mRNA changes during the progression of atherosclerosis

Medical Xpress - Cardiology

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Germans Trias i Pujol Research Institute (IGTP) have studied variations in mRNA length during the progression of atherosclerosis in a mouse model. The results, published in the journal Biomedicines, could help identify new biomarkers and potential therapeutic targets.

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Expert Panel Develops Consensus Definition, Clinical Tool for Anaphylaxis Care

HCPLive

A 46-member expert panel created a consensus anaphylaxis definition, overview, and clinical tool to aid clinicians in recognition and management across settings.

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ICHOM Develops First Standardized Dataset For Reporting Outcomes in Heart Valve Disease

American College of Cardiology

A unique international task force, comprised of representatives from cardiology and cardiothoracic societies as well as patient representatives, has developed the first standardized set of measures for heart valve disease (HVD).

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Gene Interaction Increases Patients’ Risk of Frontal Fibrosing Alopecia

HCPLive

This genome-wide meta-analysis demonstrated that changes in 2 parts of the genome both work to influence patients risk of frontal fibrosing alopecia (FFA).

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Therapeutic potential of miR-133a-transfected bone marrow mesenchymal stem cell transplantation in improving cardiac function post-myocardial infarction

Journal of Cardiothoracic Surgery

The objective of this study is to examine the therapeutic efficacy of miR-133a-transfected bone marrow mesenchymal stem cells (BM-MSCs) in restoring damaged myocardium, reducing myocardial fibrosis, and improv.

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Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD

HCPLive

Clark describes visual and anatomic improvements with aflibercept 8 mg in the PULSAR extension study, with most patients achieving extended dosing regimens.

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Management of a malignant solitary fibrous tumor of lung by uniportal video-assisted pneumonectomy: a case report

Journal of Cardiothoracic Surgery

Solitary fibrous tumor (SFT) is a rare condition first described by Klemperer and Robin in 1931. Malignant SFTs account for approximately 80% of all SFT cases, and the five-year survival for malignant SFTs is.

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Vital sign accuracy may depend on body position, research suggests

Medical Xpress - Cardiology

Body position can affect the accuracy of vital sign measurements that indicate arterial stiffnessa risk factor for heart diseaseaccording to new research. Sitting down during certain tests may cause a spike in arterial stiffness readings that does not reflect a true increase.

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Inverse relationship between circulating sphingosine-1-phosphate and precursor species and coronary artery calcification score in type 2 diabetes

Cardiovascular Diabetology

Sphingosine 1-phosphate (S1P) is a key mediator of lipid signaling with strong immunomodulatory and anti-inflammatory effects. Circulating S1P levels including S1P in high-density lip.

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Mobile app tracking blood pressure helps patients in Ghana

Medical Xpress - Cardiology

The AHOMKA platform, an innovative mobile app for patient-to-provider communication that was developed through a collaboration between the School of Engineering and leading medical institutions in Ghana, has yielded positive results in tests with patients at high risk for heart attack or stroke.

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Impaired microcirculation in the skin and subclinical atherosclerosis in individuals with dysglycaemia in a large population-based cohort

Cardiovascular Diabetology

Dysglycaemia is a known risk factor for cardiovascular disease and microcirculatory dysfunction is associated with an increased cardiovascular disease risk. The aim of this study was to investigate the prevale.

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Novel method combines heart biopsy and device implantation to reduce risk of complications

Medical Xpress - Cardiology

Endomyocardial biopsy (EMB) is a valuable method for diagnosing a range of cardiac conditions, but there is a risk of complications due to its invasive nature. Researchers have now found a way to combine right ventricular (RV) septal EMB, exploiting the benefit of 3D curved conduction system pacing (CSP) sheaths, with subsequent cardiac implantable electronic device (CIED, devices like pacemakers or defibrillators to regulate heart rhythm) implantation, using the same sheath.

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Association of glucagon-like peptide-1 receptor agonists with cardiovascular and kidney outcomes in type 2 diabetic kidney transplant recipients

Cardiovascular Diabetology

Cardiovascular disease is a leading cause of post-transplant mortality in kidney transplant recipients (KTRs), especially those with diabetes. Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) hav.

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Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis

HCPLive

In new data to be presented at AAAAI, the therapy was well-tolerated in people as young as 2 years old.

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Advanced serum lipoprotein and glycoprotein profiling for cardiovascular event prediction in type 2 diabetes mellitus: the LIPOCAT study

Cardiovascular Diabetology

Traditional risk factors cannot accurately predict cardiovascular events (CVE) in type 2 diabetes (T2D). The LIPOCAT study aimed to prospectively evaluate the clinical utility of advanced lipoprotein character.

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Rates of Iron Deficiency Differ by Clinical Definition in Heart Failure

HCPLive

Iron deficiency was more common in acute versus chronic heart failure, with notable differences in detection by numerous recommended definitions.

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Florida system names cardiothoracic chief, heart institute leader

Becker's Hospital Review - Cardiology

"Naples Comprehensive Health appoints Dr.

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Clinical Quiz: Clinical Considerations in Food Allergy Prevention

HCPLive

In this quiz, we test your knowledge of recommendations to prevent food allergy development in infants.

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Children's Hospital of Orange County opens cardiac ICU

Becker's Hospital Review - Cardiology

"Discover the new state-of-the-art cardiovascular intensive care unit at Children's Hospital of Orange County, equipped with advanced monitoring and rehabilitat

ICU 52
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BTK Inhibition as a Strategy for CSU Treatment

HCPLive

Panelists discuss how Bruton tyrosine kinase (BTK) inhibition could effectively treat both autoallergic and autoimmune chronic spontaneous urticaria (CSU).

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