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(MedPage Today) -- The novel investigational weight loss agent HU6 had mixed results specifically targeting obesity-related heart failure with preserved ejection fraction (HFpEF), based on the small HuMain-HFpEF trial. After 19 weeks on daily.
tim.hodson Wed, 10/02/2024 - 11:54 Heart failure is a rapidly growing public health issue that can be difficult to manage on a global scale. But there are tools that exist that can improve outcomes, such as guideline-directed medical therapy (GDMT). New UCLA-led research highlights the important role that these guidelines can play in reducing mortality rates for individuals suffering from heart failure with reduced ejection fraction (HFrEF), a type of heart failure affecting an estimated 29 mill
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
When it comes to assessing and managing the risk of heart disease, we all know that as a healthcare system, we could do better. The main takeaway from Tuesday’s email was that patients want a proper risk assessment, advanced testing, and a plan. I attempt to meet these requirements for my patients and for those going through the Heart Health Formula.
A team of biomechanical engineers at the University of New South Wales, working with a colleague from Queensland University of Technology and cardiac surgeons at St Vincent's Hospital, Sydney, has developed an artificial human heart left ventricle (LV) that can be used for training heart surgeons and other doctors.
Stroke, Ahead of Print. BACKGROUND:It is unknown whether hypertensive microangiopathy or cerebral amyloid angiopathy (CAA) predisposes more to anticoagulant-associated intracerebral hemorrhage (AA-ICH). The purpose of our study was to determine whether AA-ICH is associated with lobar location and probable CAA.METHODS:This was a cross-sectional analysis of patients with first-ever spontaneous ICH admitted to a tertiary hospital in Boston, between 2008 and 2023.
Stroke, Ahead of Print. BACKGROUND:It is unknown whether hypertensive microangiopathy or cerebral amyloid angiopathy (CAA) predisposes more to anticoagulant-associated intracerebral hemorrhage (AA-ICH). The purpose of our study was to determine whether AA-ICH is associated with lobar location and probable CAA.METHODS:This was a cross-sectional analysis of patients with first-ever spontaneous ICH admitted to a tertiary hospital in Boston, between 2008 and 2023.
Researchers at Karolinska Institutet have identified a new potential risk marker for cardiovascular disease in women. A new study shows an association between low levels of an anti-inflammatory antibody and the risk of heart attack and coronary heart disease.
A new HFpEF treatment might be on the horizon, after results from the EMBARK-HFpEF trial showed that BMS’ hypertrophic cardiomyopathy treatment, mavacamten (Camzyos), safely improved key HFpEF symptoms and biomarkers. Mavacamten is the only cardiac myosin inhibitor with FDA approval to treat obstructive HCM, and works by reducing heart muscle contraction and improving blood flow.
Heart failure is a rapidly growing public health issue that can be difficult to manage on a global scale. But there are tools that exist that can improve outcomes, such as guideline-directed medical therapy (GDMT).
This month in review highlights vitamin D supplementation in anemia, the prevalence of iron deficiency in US adults, and the efficacy of rpFVIII in treating acquired hemophilia A.
Researchers have identified a new potential risk marker for cardiovascular disease in women. A new study shows an association between low levels of an anti-inflammatory antibody and the risk of heart attack and coronary heart disease.
Computed tomography aortography (CTA) is used in the assessment of aortic pathologies and planning of surgical intervention. However, its dependence on iodinated contrast can result in development of contrast-.
A recent study found that after 2019, the combined cost of fatal falls among people aged ≥ 45 exceeded firearm injury costs, highlighting the economic burden of senior falls.
Acute kidney injury (AKI) represents a significant post-cardiac surgery complication, particularly prevalent among individuals with pre-existing renal dysfunction. Chronic kidney disease (CKD) is frequently ac.
"Swiss Cheese" ventricular septal defects represent a serious congenital heart disease with suboptimal clinical outcomes and a lack of consensus regarding its management. This study presents mid-term follow-up.
To compare the therapeutic effects of right vertical infra-axillary thoracotomy (RVIAT) and Standard Median Sternotomy (SMS) in the repair of atrial septal defect (ASD) and ventricular septal defect (VSD), and.
One of my colleagues was joking ,nowadays patients force us to read or even educate us. I completely concurred with him. Doctor, do you have any investigation to know how much the total plaque burden is in my coronary artery? Yes. Sure , we have many modalities, right from CT calcium to OCT, NIR, etc. How would I know , which one of them is high risk and vulnerable ?
Worcester, Mass.-based UMass Chan Medical School has partnered with South Korea-based Hallym University on an AI application to expand healthcare access for rural stroke patients.
What is the association between late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (cMRI) and sudden cardiac death (SCD) in pediatric patients with hypertrophic cardiomyopathy (HCM), and does it add to pediatric SCD risk models?
Decades ago, an association of J waves with cardiac arrest (CA) or ventricular fibrillation (VF) was reported (1), whereas J waves have been observed in individuals in the general population. Mechanistically, J waves are thought to be mediated predominantly via increased transient outward currents (Ito) characterized by bradycardia-dependent augmentation (2-3).
Hypertension, Ahead of Print. Hypertension requires increased systemic vascular resistance. Thus far, Mendelian hypertension–related genes are related to salt retention, an indirect regulatory effect. With the identification of mutated, overactive, PDE3A (phosphodiesterase 3A), we have uncovered a more direct vasoconstrictive mechanism. The autosomal-dominant syndrome features another specific phenotype, brachydactyly type E.
Stroke, Volume 56, Issue 1 , Page 209-218, January 1, 2025. Telemedicine for stroke (Telestroke) has been a key component to efficient, widespread acute stroke care for many years. The expansion of reimbursement through the Furthering Access to Stroke Telemedicine Act and rapid deployment of telemedicine resources during the COVID-19 public health emergency have further expanded remote care, with practitioners of varying educational backgrounds, and experience providing acute stroke care via tel
Despite key differences in pathological processes, both Intramural Hematomas and Aortic Dissections are Acute Aortic Syndromes repaired with similar surgical technique. The objective of this study was to deter.
What is the diagnostic yield of screening relatives of hypertrophic cardiomyopathy (HCM) patients and predictive factors for HCM development during long-term follow-up in relatives from gene-elusive families?
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