Thu.May 23, 2024

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Lifestyle-Dementia Links Persist Regardless of Risk Genes, French Study Shows

Med Page Today

(MedPage Today) -- Lifestyle and other dementia risk factors were linked with cognitive changes independently of genetic risks for Alzheimer's disease, a French prospective study found. Across nearly 5,200 people in three French cities, worse.

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Abnormal vascular thickness and stiffness in young adults with type 1 diabetes: new insights from cutting-edge ultrasound modalities

Cardiovascular Diabetology

Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in patients with Type 1 Diabetes (T1D). Early markers of CVD include increased carotid intima-media thickness (CIMT) and pulse.

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Ultraprocessed Food Consumption in Young Kids Tied to Cardiometabolic Risk Factors

Med Page Today

(MedPage Today) -- High consumption of ultraprocessed foods in children as young as 3 years of age was associated with adiposity and other cardiometabolic risk factors, a study in JAMA Network Open found. In this exclusive video interview, study.

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Illinois hospital launches 1st-of-its-kind stroke study

Becker's Hospital Review - Cardiology

A team of physicians at Rockford, Ill.-based Mercyhealth Javon Bea Hospital-Riverside participated in a unique stroke study that used patients' stem cells to promote tissue regeneration, it announced May 22.

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Tea, Coffee Consumption Linked to Lower Risk of Gout

HCPLive

An analysis of individual food groups revealed higher intakes of healthy plant foods, including tea, coffee, and whole grains were linked to a lower risk of gout.

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Popular supplement linked to increased heart, stroke risk

Becker's Hospital Review - Cardiology

Regular use of fish oil supplements can increase the risk of stroke and atrial fibrillation in the general population, but shows benefits for those with existing heart disease, a recent study found.

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Heart disease in pregnancy and risk of pre-eclampsia: a Swedish register-based study

Open Heart

Background and aims Pre-eclampsia complicates 3–5% of pregnancies worldwide and is associated with adverse outcomes for the mother and the offspring. Pre-eclampsia and heart failure have common risk factors, including hypertension, obesity and diabetes. It is not known whether heart failure increases the risk of pre-eclampsia. This study examines whether pregestational heart failure increases the risk of pre-eclampsia.

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Chest Pain in the ED: More Referrals for Cardiac Tests Not Tied to Better Outcomes

Med Page Today

(MedPage Today) -- For lower-risk patients with acute myocardial injury already ruled out for their chest pain, an increase in referrals for noninvasive cardiac testing (NICT) was not associated with improved outcomes, a retrospective cohort study.

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Global Burden of Disease Study Details Ballooning Prevalence of Metabolic Risk Factors

HCPLive

Increases in metabolic risk factors like high blood pressure and BMI have led to a 49.4% increase in global disability-adjusted life years from 2000 to 2021.

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Microvascular Injury Patterns After STEMI

American College of Cardiology

What is the prognostic significance of various microvascular injury (MVI) patterns after ST-segment elevation myocardial infarction (STEMI)?

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Case Report: Asymptomatic SARS-COV2 infection triggering recurrent Takotsubo syndrome

Frontiers in Cardiovascular Medicine

Takotsubo syndrome (TTS) is a rare disease mimicking acute coronary syndrome, often triggered by physical or emotional stress, and characterized by transient left ventricular dysfunction. Recurrences are described in about 5% of cases and may have different clinical and imaging patterns. In the present report, SARS-COV-2 infection, even in the absence of symptoms and overt emotional stress, seems correlated with recurrence of TTS, due to the absence of other recognized triggers.

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Safety, Efficacy, and Quantitative Understanding of Obstruction Impact of Aficamten in HCM

American College of Cardiology

The goal of the SEQUOIA-HCM trial was to compare the safety and efficacy of aficamten compared with placebo among patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM).

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Novel Cardiac Myosin Inhibitors Targeting Obstructive Hypertrophic Cardiomyopathy's Root Cause

HCPLive

Anjali Tiku Owens, MD, examines the unmet needs in treating obstructive hypertrophic cardiomyopathy (oHCM) and explores how novel Cardiac Myosin inhibitors (CMIs) address the root cause of the condition.

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Association between speckle tracking echocardiography and pressure-volume loops during cardiogenic shock development

Open Heart

Background The relationship between speckle tracking assessed global longitudinal strain (GLS) and Doppler-based echocardiography with basic physiological markers of cardiac function derived from pressure-volume loops is poorly elucidated. Objective We aimed to describe the association between LS and Doppler-based echocardiography and direct measurements of central haemodynamic parameters from conductance catheter-based pressure-volume loops in an animal model with increasing left ventricular (L

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8 in 8: Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC

Society of Thoracic Surgeons - Surgeon

Video 8 in 8: Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC kchalko Thu, 05/23/2024 - 09:56 In this video in the 8 in 8 Series, Dr. Dwight Owen (Ohio State University) discussed advances in biomarker testing and neoadjuvant immunotherapy for resectable non-small cell lung cancer. The talk includes a look at the role of PD-L1 testing, peri-operative chemo-immunotherapy, and the importance of NGS testing for patients with actionable mutations.

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HeartFlow's Plaque Analysis Leading The Way: 95% Accuracy vs Invasive Imaging In Newly Published REVEALPLAQUE Study

DAIC

milla1cf Thu, 05/23/2024 - 08:00 May 23, 2024 — HeartFlow, Inc. , a leader in non-invasive artificial intelligence (AI) heart care solutions, announced that the data from its REVEALPLAQUE study , highlighting the accuracy of its Plaque Analysis, was published in the European Heart Journal Cardiovascular Imaging. REVEALPLAQUE aimed to evaluate HeartFlow’s non-invasive plaque technology , an automated, deep learning-based method for identifying, characterizing, and segmenting plaque in the cor

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Does Fish Oil Supplement Increase Risk of Stroke and Atrial Fibrillation?

All About Cardiovascular System and Disorders

General information is that fish oil supplements are beneficial for cardiovascular health. Recommendation from UK National Institute for Health and Care Excellence is that people with or at high risk of cardiovascular disease consume at least one portion of oily fish a week. Still, a report published in BMJ Medicine paints a different picture. The authors reported that the regular use of fish oil supplements might be a risk factor for atrial fibrillation among general population.

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Novel Cardio Myosin Inhibitors Targeting Obstructive Hypertrophic Cardiomyopathy's Root Cause

HCPLive

Anjali Tiku Owens, MD, examines the unmet needs in treating obstructive hypertrophic cardiomyopathy (oHCM) and explores how novel cardio myosin inhibitors (CMIs) address the root cause of the condition.

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European Society of Cardiology 0/1-hour algorithm (high-sensitivity cardiac troponin T) performance across distinct age groups

Heart BMJ

Background To determine if the European Society of Cardiology 0/1-hour (ESC 0/1-h) algorithm with high-sensitivity cardiac troponin T (hs-cTnT) meets the ≥99% negative predictive value (NPV) safety threshold for 30-day cardiac death or myocardial infarction (MI) in older, middle-aged and young subgroups. Methods We conducted a subgroup analysis of adult emergency department patients with chest pain prospectively enrolled from eight US sites (January 2017 to September 2018).

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Lessons from EXPLORER-HCM: Unveiling CMIs' Potential in oHCM Treatment

HCPLive

A expert cardiologist delves into the insights gained from clinical trials assessing cardio myosin inhibitors (CMIs) for the treatment of obstructive hypertrophic cardiomyopathy (oHCM), with a particular focus on the EXPLORER-HCM trial, which investigated the efficacy and safety of mavacamten in managing oHCM.

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Wide complex tachycardia with two QRS morphologies: what is the mechanism?

Heart BMJ

Clinical introduction A man in his 50s presented to the emergency department with palpitations. He had a background of arrhythmic right ventricular cardiomyopathy. He had previously undergone the placement of a dual-chamber implantable cardioverter-defibrillator for atrioventricular block and ventricular tachycardia (VT). The device was programmed in a dual-chamber rate-modulated pacing mode with a lower rate of 80 beats per minute (bpm), an upper track/sensor rate of 120 bpm, paced atrioventric

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The Nuanced Challenges of Diagnosing, Managing Ehlers-Danlos Syndrome, with Andrew Sharobeem, DO

HCPLive

Andrew Sharobeem, DO, discusses the major unmet needs among patients with Ehlers-Danlos Syndrome, including awareness among healthcare providers.

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10 states with the most vascular surgery residents

Becker's Hospital Review - Cardiology

Discover which state has the highest number of vascular surgery residents in 2024 according to the NRMP's "Main Residency Match" report.

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Psoriatic Arthritis Patients in UK Included Equally, Across All Degrees of Deprivation

HCPLive

These data highlight the role of the National Health Service, though the relationship between socio-economic background and health outcomes remains complex.

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Safety and Efficacy of Ninerafaxstat in Nonobstructive HCM

American College of Cardiology

What is the safety and tolerability of ninerafaxstat in patients with symptomatic, nonobstructive hypertrophic cardiomyopathy (nHCM)?

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Comparison of quality of life in patients with mitral valve replacement and mitral valve repair in Imam Ali Hospital during 2014 to 2020: a cross-sectional study

Journal of Cardiothoracic Surgery

Mitral valve failure is one of the most common valvular heart diseases worldwide. Valve replacement and repair have an impact on the quality of life of patients. Therefore, the present study was conducted to c.

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Wearable Biosensors for Congenital Heart Disease: Key Points

American College of Cardiology

The following are key points to remember from a science advisory on advancing wearable biosensors for patients with congenital heart disease.

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Peak Frequency Annotation Algorithm Guided Slow Pathway Ablation in Typical Atrioventricular Nodal Re-entrant Tachycardia

HeartRhythm

The slow-pathway potential is difficult to annotate because it is buried within the atrial potential. Omnipolar technology Near Field (OTNF) in Ensite X can automatically annotate the peak frequency potential associated with acquired intracardiac electrograms.

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Data Interoperability for Ambulatory Monitoring of Cardiovascular Disease: A Scientific Statement From the American Heart Association

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Ahead of Print. Wearable devices are increasingly used by a growing portion of the population to track health and illnesses. The data emerging from these devices can potentially transform health care. This requires an interoperability framework that enables the deployment of platforms, sensors, devices, and software applications within diverse health systems, aiming to facilitate innovation in preventing and treating cardiovascular disease.

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Machine Learning for Prediction of Ventricular Arrhythmia Episodes from Intracardiac Electrograms of Automatic Implantable Cardioverter-Defibrillators

HeartRhythm

Despite the implantable cardioverter defibrillator’s (ICD) effectiveness in saving patients with life-threatening ventricular arrhythmias (VAs), the temporal occurrence of VA following ICD implantation is unpredictable.

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Repeat Mitral Valve Interventions After Transcatheter Edge-to-Edge Repair: The COAPT Trial

The American Journal of Cardiology

Publication date: Available online 23 May 2024 Source: The American Journal of Cardiology Author(s): Bahira Shahim, David J. Cohen, Federico M. Asch, Jeroen Bax, Isaac George, Andreas Rück, Ori Ben-Yehuda, Saibal Kar, D. Scott Lim, John T. Saxon, Zhipeng Zhou, JoAnn Lindenfeld, William T. Abraham, Michael J. Mack, Gregg W.

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Osteosarcopenia — A New Risk Factor for Mortality After TAVR

NEJM Journal Watch - Cardiology

The combination of low muscle mass and bone density was associated with a threefold increase in 1-year mortality risk.

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Is diabetes still a risk factor for PCI-related outcomes in the era of imaging-guided PCI?

The American Journal of Cardiology

Publication date: Available online 22 May 2024 Source: The American Journal of Cardiology Author(s): Domenico Simone Castiello, Raffaele Piccolo, Giovanni Esposito

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Returning Athletes to Play

NEJM Journal Watch - Cardiology

In new consensus guidance on arrythmias in athletes, the focus is on returning to play and avoiding unnecessary restrictions.

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Diastology of the Transplanted Heart: Is the Geometrical Relationship of the Left Atrium the Missing Link?

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print.

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To Test or Not to Test? The Utility of Noninvasive Cardiac Testing for Chest Pain Without Myocardial Infarction

Circulation: Cardiovascular Quality & Outcomes

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

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June 2024 Stroke Highlights

Stroke Journal

Stroke, Volume 55, Issue 6 , Page 1467-1467, June 1, 2024.

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