Metabolite Reductions Reveal Insights into Chronic Pruritus of Unknown Origin Pathogenesis
HCPLive
AUGUST 28, 2024
A new study found patients with chronic pruritus of unknown origin have reductions in 15 metabolites compared to healthy controls.
Wed.Aug 28, 2024
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More people at risk of hereditary heart disease than thought
Science Daily - Heart Disease
AUGUST 28, 2024
A new study used data from the UK Biobank to analyze the genes of 469,789 people in the UK and found that one in 1,000 possessed genetic variants with a likely link to cardiac transthyretin (ATTR) amyloidosis.
ESC Congress 2024 Lipidology Preview, with Professor Kausik Ray
HCPLive
AUGUST 28, 2024
Kausik Ray, MD, discusses what trials and new data in lipidology he is most looking forward to from the upcoming ESC Congress.
Novartis Leqvio’s Case for Broader ASCVD Prevention
CardiacWire
AUGUST 28, 2024
Novartis’ Leqvio took a major step towards establishing itself as an LDL-C monotherapy, after topline results from the V-MONO study revealed significant LDL-C reductions in patients with low or moderate ASCVD risks. Available via twice-yearly injections, Leqvio (inclisiran) is an siRNA therapy that reduces LDL-C levels by inhibiting the PCSK9 protein.
Narrowband UVB Phototherapy Effective According to Patients with Psoriasis, Eczema
HCPLive
AUGUST 28, 2024
These data reaffirm NB-UVB phototherapy’s use in treating patients with atopic dermatitis and psoriasis, suggesting improvement in patient-reported outcome measures.
Antithrombotic Therapy After Acute Coronary Syndrome or PCI in Atrial Fibrillation
American College of Cardiology
AUGUST 28, 2024
The goal of the AUGUSTUS trial was to evaluate the role of dual therapy compared with triple therapy among patients with atrial fibrillation undergoing coronary revascularization.
Treatment option for fibromyalgia
HCPLive
AUGUST 28, 2024
This discussion explores the treatments available for managing fibromyalgia symptoms and evaluates the efficacy of antidepressants, including SNRIs, in alleviating pain and other related symptoms.
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Taking Ubrogepant May Prevent Migraines if Taken at First Warning Signs
HCPLive
AUGUST 28, 2024
Taking ubrogepant at the first signs of a migraine, before headache onset, significantly reduces migraine symptoms and improves daily function, a study in Neurology reveals.
Managing DOACs Perioperatively
NEJM Journal Watch - Cardiology
AUGUST 28, 2024
Drawing from guidelines and a general review of the literature, experts offer management recommendations for direct-acting oral anticoagulants before and after invasive interventions.
Phase 2 Data Supports the Effectiveness, Safety of NBI-1117568 for Schizophrenia
HCPLive
AUGUST 28, 2024
A phase 2 trial met its primary endpoint, showing NBI-1117568, the first M4 selective agonist, is effective and safe at treating adult schizophrenia.
The Global Applicability of the DanGer Shock Trial
American College of Cardiology
AUGUST 28, 2024
Randomized trials of patients in cardiogenic shock (CS) have been challenging to conduct. The DanGer Shock (Microaxial Flow Pump in Infarct-Related Cardiogenic Shock) trial was an important study in this space that was successfully concluded after 10 years because of slow recruitment.
Tralokinumab Effective for Eczema Among Older Patients, Those with Severe Comorbidities
HCPLive
AUGUST 28, 2024
These data are encouraging for tralokinumab, though additional observational research with more individuals with atopic dermatitis or longer follow-up periods may be necessary.
Emerging Trends in the Care of Type B Aortic Dissections
The American Journal of Cardiology
AUGUST 28, 2024
Publication date: Available online 28 August 2024 Source: The American Journal of Cardiology Author(s): John F Eidt, Angela L Gucwa, Erin Cha, Steven E Hohmann, Javier Vasquez Jr
Salvage EUS-RV, Precut Sphincterotomy Comparable for Difficult Bile Duct Cannulation
HCPLive
AUGUST 28, 2024
Endoscopic ultrasound-guided rendezvous technique and precut sphincterotomy had similar technical success, and failure with one method could be successfully cannulated with the other.
Anticoagulation Alone vs. Anticoagulation Plus Aspirin or DAPT After LAAO
American College of Cardiology
AUGUST 28, 2024
What are the patterns of antithrombotic medication strategies at discharge following left atrial appendage occlusion (LAAO) with the Watchman FLX device in real-world practice, and the risk of adverse events among the different antithrombotic regimens?
Mifeprestone for Treatment of Hypercortisolism
HCPLive
AUGUST 28, 2024
Experts discuss the CATALYST study's evaluation of mifepristone for hypercortisolism patients with hard-to-manage type 2 diabetes, its mechanism of action, suitable patient populations, treatment approaches for those with adrenal tumors, and factors determining surgical candidacy.
Five-year outcomes of measured and predicted prosthesis-patient mismatch following transcatheter aortic valve implantation.
The American Journal of Cardiology
AUGUST 28, 2024
Publication date: Available online 28 August 2024 Source: The American Journal of Cardiology Author(s): Karim Al-Azizi, Ghadi Moubarak, Asim Mohiuddin, Molly Szerlip, Srinivasa Potluri, Katherine Harrington, Justin Schaffer, William Brinkman, Amro Alsaid, Zuyue Wang, Jonathan Ladner, Rahul Gunukula, Colleen Parro, Tsung-Wei Ma, Robert Stoler, Yashasvi Chugh, Subhash Banerjee, Timothy Mixon, Robert J Widmer, Angel Caldera
Switch to Faricimab Improves Short-Term Anatomical Outcomes in DME
HCPLive
AUGUST 28, 2024
After an initial switch to faricimab, anatomical measures showed improvement while no functional improvement was identified in real-world data.
Corrigendum to ‘Clinical Impact of Perfusion Balloon for ST-Segment Elevated Myocardial Infarction: RYUSEI Study’ [Am J Cardiol 223 (2024) start 23-51]
The American Journal of Cardiology
AUGUST 28, 2024
Publication date: Available online 28 August 2024 Source: The American Journal of Cardiology Author(s): Masami Nishino, Yasuyuki Egami, Hitoshi Nakamura, Masaru Abe, Mizuki Ohsuga, Hiroaki Nohara, Shodai Kawanami, Kohei Ukita, Akito Kawamura, Koji Yasumoto, Masaki Tsuda, Naotaka Okamoto, Yasuharu Matsunaga-Lee, Masamichi Yano
Urate Lowering Therapy Limits Gout Flares During Hemodialysis
HCPLive
AUGUST 28, 2024
Dialysis efficiency was similar between the ULT group and the no ULT group.
Seeking the Optimal Antithrombotic Therapy After Left Atrial Appendage Occlusion
NEJM Journal Watch - Cardiology
AUGUST 28, 2024
In a small, open-label, randomized trial, risk for bleeding or thrombotic events was lower with low-intensity direct oral anticoagulants than with dual antiplatelet therapy.
Tried and True: Exploring Metformin’s Potential for Geographic Atrophy
HCPLive
AUGUST 28, 2024
A new treatment era was born with first-time geographic atrophy approvals in 2023, but many are still searching for the next addition to the treatment landscape.
Epinephrine for Refractory No-Reflow During Percutaneous Coronary Interventions
The American Journal of Cardiology
AUGUST 28, 2024
Publication date: Available online 28 August 2024 Source: The American Journal of Cardiology Author(s): Fernando Alfonso, Josep Gómez-Lara, Fernando Rivero
Social Determinants of Health in Cardiology, Aortopathy in Children, Cardiac CT Following Left Atrial Appendage Occlusion
American College of Cardiology
AUGUST 28, 2024
In this week’s View, Dr. Eagle looks at the 2024 ACC/AHA key data elements and definitions for social determinants of health in cardiology.
Reflections on the Win Ratio With Time-to-Event Outcomes
Circulation: Heart Failure
AUGUST 28, 2024
Circulation: Heart Failure, Ahead of Print.
Comparing Different Holter Software
Cardiomatics
AUGUST 28, 2024
When choosing a Holter software, it’s crucial to consider the specific needs of your practice. The right software can streamline your workflow, enhance diagnostic accuracy, and improve patient outcomes. Two key dimensions to consider from a product perspective are how the algorithm used for analysis was developed and how the software is deployed.
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