Mon.Jan 20, 2025

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Association between cardiopulmonary bypass duration and early major adverse cardiovascular events after surgical repair of supravalvular aortic stenosis

Frontiers in Cardiovascular Medicine

BackgroundPatients who underwent surgical repair of supravalvular aortic stenosis (SVAS) are at high risk for postoperative major adverse cardiovascular events (MACE). This study aimed to investigate the association between cardiopulmonary bypass (CPB) duration and MACE occurring during postoperative hospitalization or within 30 days post-surgery.MethodsPatients who underwent surgical repair of SVAS from 2002 to 2019 at Beijing Fuwai Hospital and Yunnan Fuwai Hospital were included in this study

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GLP-1 Agents' Risks and Benefits Broader Than Previously Thought

Med Page Today

(MedPage Today) -- An observational study of 175 health outcomes using Veterans Affairs (VA) data for nearly 2 million individuals uncovered new insights about possible risks and benefits of GLP-1 receptor agonists. Over a median of 3.68 years.

Outcomes 126
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Identifying etiologies of heart failure using non-contrast cardiac magnetic resonance imaging: cine imaging, T1 and T2 mapping, and texture analysis for T1 mapping

Frontiers in Cardiovascular Medicine

ObjectiveThe aim of this retrospective study was to evaluate the usefulness of non-contrast cardiac magnetic resonance imaging, including cine imaging, T1 and T2 mapping, and texture analysis for T1 mapping, for identifying etiologies of heart failure (HF).MethodsForty-seven patients with HF were examined using a 1.5T scanner. Cine imaging parameters and native T1 and T2 values at the mid-septal segment were measured.

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High Pollen Exposure Linked to Increased Chronic Respiratory Mortality

HCPLive

A new study found high concentrations of pollen from 3 species classesragweed, deciduous trees, and grassare linked to increased chronic respiratory mortality.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Remote patient monitoring in heart failure: A comprehensive meta‐analysis of effective programme components for hospitalization and mortality reduction

European Journal of Heart Failure

Remote patient monitoring in heart failure (HF). Abstract Aims Methods of non-invasive remote patient monitoring (RPM) for heart failure (HF) remain diverse. Understanding factors that influence the effectiveness of RPM on HF-related and all-cause hospitalizations, mortality, and emergency department visits is crucial for developing successful RPM interventions.

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Heart attacks and high blood pressure are on the rise in Africa—what does air pollution have to do with it?

Medical Xpress - Cardiology

Air pollution has an alarming effect on global health. In 2019, it was responsible for 4.2 million global deaths. Inhaling air pollution harms health in many different ways beyond simply having effects on the lungs. Over 70% of air pollution deaths are due to cardiovascular diseasesdiseases of the heart and blood vessels, such as heart attacks and strokes.

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Lower blood pressure for diabetic patients can reduce cardiovascular disease

Medical Xpress - Cardiology

People with type 2 diabetes had significantly fewer heart attacks, strokes, heart failures, and deaths from cardiovascular disease when their blood pressure was lower than the current standard goal, a UT Southwestern Medical Center researcher and his colleagues found. The research, published in the New England Journal of Medicine, offers evidence for developing new clinical guidelines for improving cardiovascular health in this growing population.

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Repurposing Medications for the Treatment of Patients with COPD

HCPLive

Joselyn Rojas-Quintero, MD, speaks about her team's current research into COPD treatment on this issue of The Respiratory Report.

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Supervised exercise can improve mental health and quality of life in people with coronary heart disease

Medical Xpress - Cardiology

A study led by researchers from the University of Granada, carried out in collaboration with the University of Castilla-La Mancha and the Radboud University Medical Center (The Netherlands), has shown that the context in which physical exercise is performed plays a key role in improving the mental health and quality of life of patients with coronary heart disease.

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Traction force microscopy of cardiomyocytes

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 21 January 2025; doi:10.1038/s41569-025-01123-4 In this Tools of the Trade article, Lyall discusses the use of traction force microscopy to assess the contractile function of individual cardiomyocytes.

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Welcome Back to The Respiratory Report

HCPLive

In this summary, we highlight the latest issue of our pulmonology research quarterly newsletter powered by the American Lung Association Research Institute.

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Survivorship After Cardiogenic Shock

Circulation

Circulation, Volume 151, Issue 3 , Page 257-271, January 21, 2025. Advances in critical care therapies for patients with cardiogenic shock (CS), including temporary mechanical circulatory support and multidisciplinary shock teams, have led to improved survival to hospital discharge, ranging from 60% to 70%. After their index hospitalization, however, survivors of CS may continue to face cardiac as well as extracardiac sequelae of these therapies and complications for years to come.

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Study Describes Clinical Features, Prognosis of Patients with IgAN, Nephrotic Syndrome

HCPLive

Findings show differences in the clinicopathological characteristics and prognosis of patients with IgAN and nephrotic syndrome across renal pathologies.

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ACC CardiaCast: PulseCheck: Palliative Care in Patients with Heart Disease: High-Risk Procedures in Our High-Risk Patients

American College of Cardiology

In this episode, Andrea Price, MS, AACC hosts Richard A. Josephson, MS, MD, FACC, Christy Cantey DNP, FNP-C, AACC, CCK, and Gwen M. Bernacki, MD MHSA to share insights for high-risk procedures in our high risk patients: we can, but should we?

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Exploring Duloxetine for Depression in COPD: A Pilot Study

HCPLive

Pilot study tests duloxetines feasibility for depression in COPD, examining patient/physician attitudes, treatment barriers, and therapy effects.

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Surgeon Preference Factors into Survival Outcomes Analyses for Multi- and Single-Arterial Bypass Grafting

Society of Thoracic Surgeons - Congenital

News Surgeon Preference Factors into Survival Outcomes Analyses for Multi- and Single-Arterial Bypass Grafting pvaldez Mon, 01/20/2025 - 13:46 1 min read

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FDA Accepts Plozasiran NDA for Familial Chylomicronemia Syndrome

HCPLive

The FDA has assigned a Prescription Drug User Fee Act (PDUFA) target action date of November 18, 2025.

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The Hub Returns

Society of Thoracic Surgeons - Early Career

ack for STS 2025, The Hub is your one-stop shop for programs, sessions, networking and mentoring tailored for CT surgery trainees and early-career surgeons.

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Pegloticase Does Not Increase Risk of CV/TE Events in People With Gout

HCPLive

A post-hoc analysis evaluated pooled data from 4 trials of pegloticase.

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STS 2025: Celebrating the Surgeons Behind the Masks

Society of Thoracic Surgeons - Early Career

STS's 61st Annual Meeting in Los Angeles brings together cardiothoracic surgeons from around the world and features late-breaking scientific research, cutting-edge technologies, and meaningful networking opportunities.

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Metabolic Reprograming in Alveolar Epithelial Cells Type 2: Repurposing Old Drugs for Emphysema Treatment

HCPLive

The importance of AT2 cells in repairing injured alveoli and maintaining alveoli number and lumen size suggests that COPD therapies may be implemented to improve AT2 cell biology and/or increase AT2 cell numbers.

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Volume-Outcome Relationship of Norwood Procedures: Insights from the NPC-QIC Database

Society of Thoracic Surgeons - Adult Cardiac

In this years James S. Tweddell Memorial Paper presentation, Dr. Reilly Hobbs will discuss the relationship between the volume of Norwood procedures performed at a center and patient outcomes.

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Small Airway Mucus Plugging in Severe Asthma: Insights and Implications

HCPLive

Exploring mucus plugging in severe asthma, focusing on small airway dysfunction, MUC5AC expression, and epithelial heterogeneity using advanced methods.

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ADMET-AI Enables Interpretable Predictions of Drug-Induced Cardiotoxicity

Circulation

Circulation, Volume 151, Issue 3 , Page 285-287, January 21, 2025.

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Insights Into the Role of Mucus Plugging in Asthma

HCPLive

This interview in the latest issue of The Respiratory Report features Stephen Schworer, Md, PhD, discussing the role of mucus plugging in severe asthma.

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From the Literature

Circulation

Circulation, Volume 151, Issue 3 , Page 272-273, January 21, 2025.

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Emerging Therapies: a look at the current data: PROTECT study

HCPLive

Panelists discuss how the PROTECT studys results enhance the understanding of emerging therapies for IgA nephropathy, focusing on their potential to reduce proteinuria and modify disease progression.

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Correction to: Comparative Cardiovascular Effectiveness of Empagliflozin Versus Dapagliflozin in Adults With Treated Type 2 Diabetes: A Target Trial Emulation

Circulation

Circulation, Volume 151, Issue 3 , Page e30-e30, January 21, 2025.

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Duloxetine for Patients with COPD Suffering from Comorbid Depression

HCPLive

Abebaw Yohannes, MSc, PhD, speaks about his teams pilot study designed to assess the use of duloxetine for patients with COPD and comorbid depression.

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Correction to: Risk of Stroke or Systemic Embolism According to Baseline Frequency and Duration of Subclinical Atrial Fibrillation: Insights From the ARTESiA Trial

Circulation

Circulation, Volume 151, Issue 3 , Page e29-e29, January 21, 2025.

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Emerging Therapies: a look at the current data: NefIgArd study

HCPLive

Panelists discuss how the NefIgArd study findings contribute valuable insights into the efficacy of emerging therapies for IgA nephropathy, emphasizing their role in reducing proteinuria and improving patient outcomes.

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An Advocacy Agenda for the Human Brain: Moving From Brain Health to Brain Capital

Circulation

Circulation, Volume 151, Issue 3 , Page e24-e26, January 21, 2025.

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Ethical Excellence: Returning Computed tomography rEsults to actIVE Lung Health Cohort participants (RECEIVE)

HCPLive

The RECEIVE study develops tools to standardize returning chest CT results in the Lung Health Cohort, improving engagement and ethical practices.

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Response by Park and Kang to Letter Regarding Article, “Ertugliflozin for Functional Mitral Regurgitation Associated With Heart Failure: EFFORT Trial”

Circulation

Circulation, Volume 151, Issue 3 , Page e28-e28, January 21, 2025.

Article 45
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Enhancing Standards for Ethical Responsibilities within Clinical Research

HCPLive

This summarizes the latest in our pulmonology research quarterly newsletter powered by the American Lung Association Research Institute.

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Letter by Wang and Peng Regarding Article, “Ertugliflozin for Functional Mitral Regurgitation Associated With Heart Failure: EFFORT Trial”

Circulation

Circulation, Volume 151, Issue 3 , Page e27-e27, January 21, 2025.

Article 45