Tue.Jul 09, 2024

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Consequences of ionizing radiation exposure to the cardiovascular system

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 10 July 2024; doi:10.1038/s41569-024-01056-4 In this Review, Wu and co-workers describe the consequences of radiation exposure on the cardiovascular system, drawing insights from individuals exposed to whole-body radiation (including nuclear and medical workers) and from patients with cancer undergoing radiation therapy.

Cancer 116
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American Heart Association Announces New 2024-2025 National Volunteer Leaders

DAIC

The American Heart Association, commemorating its 100th year, has announced its volunteer leadership for fiscal year 2024-2025, which includes Keith Churchwell, MD, FAHA, a cardiologist renowned as a health equity champion, and Marsha Jones, an executive leader in workplace diversity and inclusion. Image courtesy: American Heart Association christine.book Tue, 07/09/2024 - 10:55 July 9, 2024 — The American Heart Association , celebrating 100 years of lifesaving service as the world’s leading non

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SGLT2 Inhibitor, GLP-1 RA Combination Improves Cardiovascular, Kidney Outcomes in Diabetes

HCPLive

Findings from a meta-analysis examining 12 trials including more than 70,000 patients with diabetes support combining SGLT2 inhibitors and GLP-1 RAs.

Diabetes 119
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A man in his 50s with unwitnessed VF arrest, defibrillated to ROSC, and no STEMI criteria on post ROSC ECG. Should he get emergent angiogram?

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his 50s was found by his family in cardiac arrest of unknown duration. His family started CPR and called EMS, who arrived to find him in ventricular fibrillation. 15 minutes after EMS arrival, after at least 6 defibrillations, the patient achieved sustained ROSC. He arrived to the ED with severe hypotension, heart rate in the 70s, unable to follow commands but moving all extremities requiring restraint and sedation, respiratory rate around 24/min being supporte

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Almost Half of US Counties Have No Cardiologists Despite Higher Prevalence of CV Risk Factors, Mortality

DAIC

Getty Images mtaschetta-millane Tue, 07/09/2024 - 07:23 July 9, 2024 — Disparities in cardiovascular disease outcomes between urban and rural areas continue to widen, yet nearly half of U.S. counties do not have a practicing cardiologist. According to a new analysis published in JACC , the flagship journal of the American College of Cardiology, these counties tend to be more rural and socioeconomically disadvantaged, with a greater burden of cardiovascular disease, thus highlighting deep geogr

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Delaying diabetes with diet and exercise for four years results in better long-term health

Science Daily - Heart Disease

Individuals diagnosed with prediabetes can reduce their long-term risk of death and diabetes-related health complications if they delay the onset of diabetes for just four years through diet and exercise, according to new findings.

Diet 107
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Journal Club 6 Which Older Patients Can Safely Forgo CT Head After a Fall? The Falls Decision Rule

ECG Cases

The decision of whether or not to order a CT head for an older patient who falls is one I need to make on almost every shift. The Canadian CT Head Rule does not apply to older patients. Does the recently derived Falls Decision Rule give us an answer to the question of which older patients can safely forego a CT head after a fall? Dr. Rohit Mohindra reviews the latest evidence in this EM Cases Journal Club.

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Diet and exercise for obese mothers could lower cardiovascular risk in children

Medical Xpress - Cardiology

Researchers from King's have identified evidence to suggest that lifestyle changes could offset the risk of some adult heart disorders that result from maternal obesity and changes in fetal heart development.

Obesity 76
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Roflumilast Cream Receives FDA Approval for Atopic Dermatitis

HCPLive

This decision by FDA officials resulted from the INTEGUMENT study findings which determined that once-daily roflumilast led to rapid eczema clearance and significant disease reductions.

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After cardiac arrest, women more likely to suffer anxiety, depression than men

Medical Xpress - Cardiology

Women who survive cardiac arrest are more likely to suffer anxiety or depression than male survivors, a new study warns.

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Arcutis Offers Update on Application for Roflumilast Cream 0.15% with FDA

HCPLive

Arcutis Biotherapeutics announced the update and indicated the FDA was working to finalize the action letter on July 09, 2024, which was 2 days after the assigned PDUFA date of July 07, 2024.

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Study compares rivaroxaban, warfarin with apixaban for cirrhosis, atrial fibrillation

Medical Xpress - Cardiology

For patients with cirrhosis and nonvalvular atrial fibrillation (AF), initiators of rivaroxaban or warfarin versus apixaban have significantly higher rates of major hemorrhage, according to a study published online July 9 in the Annals of Internal Medicine.

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Psoriasis, Psoriatic Arthritis Linked to Factors Contributing to Polyneuropathy Risk

HCPLive

A study found patients with psoriasis and psoriatic arthritis had a polyneuropathy relative risk of 22.09. However, an analysis revealed the neuropathy risk was not significant.

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Study investigates vascular dysfunction as mechanism underlying link between heart and bone health in older adults

Medical Xpress - Cardiology

Osteoporosis and cardiovascular disease tend to co-occur in older adults. A new study published in the Journal of Bone and Mineral Research measured vascular dysfunction in relation to bone loss and deterioration in bone microarchitecture to investigate whether this is due to shared risk factors or if there is a causal pathway by which vascular dysfunction with aging leads to skeletal fragility.

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Study Examines the Complex Impact of Gout on Work, Employment

HCPLive

The study identified 6 key themes highlighting how gout impacts work life, including the severity of physical symptoms, the challenge of physically demanding jobs, and emotional and social experiences.

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What’s Next for Lipoprotein(a)?: Key Points

American College of Cardiology

The following are key points to remember from an expert panel discussion convened by the National Lipid Association (NLA) in November 2023 to address unmet needs regarding lipoprotein(a) [Lp(a)].

Article 58
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Study Shows Bempedoic Acid Comparable to Statins in Cardiovascular Protection

HCPLive

An analysis of CLEAR Outcomes and CTTC data suggest bempedoic acid holds its own relative to statin therapy for cardiovascular risk reduction normalized to 1 mmol/L reduction in LDL-C.

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Heart failure patients see no benefits in severe salt restriction

Becker's Hospital Review - Cardiology

New study finds strict sodium restrictions may not benefit heart failure patients. Moderate salt intake of 3.0-4.

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Dupilumab for Atopic Dermatitis Led to Improvements in Comorbid Asthma, Other Benefits

HCPLive

These findings also highlighted the necessity of identifying the clinically relevant comorbidities of asthma and allergic rhinitis in a proactive manner.

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Metabolic score for insulin resistance (METS-IR) predicts all-cause and cardiovascular mortality in the general population: evidence from NHANES 2001–2018

Cardiovascular Diabetology

The prevalence of obesity-associated insulin resistance (IR) is increasing along with the increase in obesity rates. In this study, we compared the predictive utility of four alternative indexes of IR [triglyc.

Obesity 52
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Survey Reports Heterogeneity in Iron Deficiency Management in Heart Failure

HCPLive

Online survey data underlines notable discrepancies across various aspects of ID screening and supplementation in clinical practice for patients with HF.

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Adaptation of risk prediction equations for cardiovascular outcomes among patients with type 2 diabetes in real-world settings: a cross-institutional study using common data model approach

Cardiovascular Diabetology

To adapt risk prediction equations for myocardial infarction (MI), stroke, and heart failure (HF) among patients with type 2 diabetes in real-world settings using cross-institutional electronic health records.

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Left anterior mini-thoracotomy: an alternative approach for pulmonary valve replacement after surgically corrected tetralogy of fallot

Journal of Cardiothoracic Surgery

Pulmonary regurgitation (PR) remains a common sequela in patients following surgically corrected TOF, and may lead to progressive right ventricle dilatation and dysfunction. The conventional approach of redo-s.

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Semaglutide found to cut major adverse cardiovascular events in people with overweight, obesity

Medical Xpress - Cardiology

Semaglutide reduces cardiovascular events, regardless of baseline glycated hemoglobin (HbA1c), among people with overweight or obesity and established atherosclerotic cardiovascular disease, according to a study published online June 22 in Diabetes Care.

Obesity 52
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Revolutionizing thoracic surgery education: a bibliometric analysis of the past decade’s literature

Journal of Cardiothoracic Surgery

Thoracic surgery is a complex field requiring advanced technical skills and critical decision-making. Surgical education must evolve to equip trainees with proficiency in new techniques and technologies.

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Worse-Rated Cardiologists; Afib Pulsed Field Ablation Safety; Healthy Gut Microbe?

Med Page Today

(MedPage Today) -- Female cardiologists and older cardiologists tended to get lower average online ratings relative to their peers. (JACC: Advances) Given the geographic clusters in access to cardiovascular care, almost half of U.S. counties had.

AFIB 52
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Patent conversion of a novel closed chest drainage device

Journal of Cardiothoracic Surgery

Closed chest drainage is typically necessary following Lobar and Sublobar resections to evacuate gases and fluids from the thoracic cavity, eliminate residual pleural space for lung expansion, and maintain neg.

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Meta-Analysis Favors Complete Coronary Revascularization in a Single Go

Med Page Today

(MedPage Today) -- The latest evidence moves the needle closer in favor of one-go complete revascularization for people with acute myocardial infarction (MI) and multivessel coronary artery disease, according to an updated network meta-analysis.

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Triage of Ambulatory Patients With Advanced HF

American College of Cardiology

What are 2-year clinical outcomes for ambulatory patients with advanced systolic heart failure (HF) on maximally tolerated evidence-based therapies?

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Vaccine-Related Hematuria in IgA Nephropathy Not Impacted by Infection-Related Hematuria

HCPLive

Gross hematuria due to infection was not associated with the incidence of gross hematuria due to vaccination in patients with IgAN who received COVID-19 mRNA vaccination.

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Return-to-Work for Patients in High-RiskProfessions Diagnosed with a Sudden Cardiac Death-Predisposing Genetic Heart Disease

HeartRhythm

Akin to athletes, there are high-risk professions for which employers have struggled to combine on-the-job safety with the diagnosis of a genetic heart disease (GHD). Such professions involve intense exercise, increased risk, or situations where syncope could pose a risk, also to others. Nowadays, more cases of GHDs are identified through employment-based evaluations or cascade genetic screening, leading to potentially unnecessary delays in ‘return-to-work’ (RTW) or even suspension in the absenc

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Pulmonology Month in Review: June 2024

HCPLive

In this summary of major news in pulmonology covered in June 2024, approvals by the FDA, new episodes of Lungcast, news on COPD, and more are highlighted.

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Urban Blue and Green Spaces and CAC in Black Individuals

American College of Cardiology

Is there a relationship between race, socioeconomic status, and coronary artery calcification (CAC) and proximity to urban blue and green spaces?

Article 45
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Statins Reduce CVD Risk in Adults 75 and Older, Study Finds

HCPLive

First-time comprehensive evidence demonstrates the benefit of statins in reducing CVD risk for older adults with high cholesterol.

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Perventricular device closure of the ventricular septal defects in children-first experience in the United Arab Emirates

Journal of Cardiothoracic Surgery

Ventricular septal defect (VSD) is the most common congenital cardiac malformation, accounting for approximately 30% of congenital heart defects. Conventional surgical repair using cardiopulmonary bypass is in.

VSD 40
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Survey Showcases Gender Perceptions on PsA, Women Seen as Suffering More

HCPLive

A survey shows females with PsA have a greater disease burden than males with PsA.

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Electrophysiologic and Cardiovascular Manifestations of Duchenne and Becker Muscular Dystrophies

HeartRhythm

There have been significant advances in the diagnosis and management of the hereditary muscular disorders Duchenne and Becker Muscular Dystrophy (DMD and BMD). Cardiac electrophysiologic and Cardiovascular involvement has long been important in the surveillance, care, and prognosis of patients with both BMD and DMD, and is the leading cause of mortality in patients with DMD.