Fri.Nov 22, 2024

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Cardiology collaboration advances machine learning predictions for AFib after stroke

Medical Xpress - Cardiology

Researchers at Penn State are using machine learning and existing electrocardiogram (ECG) data to help doctors make more accurate predictions. A team of artificial intelligence engineers, in collaboration with a team of physicians from Penn State Heart and Vascular Institute, is working to develop novel algorithms for point-of-care, in-house use and for technology licensing.

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Study Highlights Wound Closure Techniques Following Wide Excision for HS

HCPLive

This meta-analysis showed that both secondary closure techniques substantially reduce the risk of hidradenitis suppurativa recurrence compared to primary direct closure.

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Standing at work can be detrimental to blood pressure

Science Daily - Heart Disease

A new study found that prolonged standing at work had a negative impact on the research participants' 24-hour blood pressure. In contrast, spending more time sitting at work was associated with better blood pressure. The study suggests that activity behavior during working hours may be more relevant to 24-hour blood pressure than recreational physical activity.

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Physiology Friday #245: Fitness Protects against Neurodegenerative Diseases—Even in Those at the Greatest Risk

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post. Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

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Medical Ethics Unpacked: Ethical Foundations and Background of Euthanasia & Medically-Assisted Suicide

HCPLive

In part 1 of this 2-part discussion, hosts explore the ethical foundation and background of euthanasia and medically-assisted suicide.

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The Ultimate Path to Health Isn’t a Pill, It’s Behavioral Change.

Dr. Paddy Barrett

Achieving your health goals largely depends on your behaviour and actions. Most of us know what we need to do. The problem is, we don’t do those things. Even when we do change our behaviours, we often don’t understand why we did so. Living longer and having a higher quality of life is largely determined by one's actions and decisions throughout life.

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Protein and Glycine in Allergens: Negative Correlation with Allergy Prevalence

HCPLive

In this analysis, the investigators systematically assessed links between the macronutrient profiles of common allergenic foods and corresponding prevalence of food allergy.

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More Trending

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AASM Updates Clinical Guidelines for Restless Legs Syndrome

HCPLive

Following the publication of the new RLS recommendations, HCPLive spoke with John Winkelman, MD, PhD, chair of the AASM committee that revised the guidelines.

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40 Days of Giving: Cassling Employees Team Up to Give Back

Cassling

This year, Cassling is proud to celebrate 40 years as a company providing innovative solutions to healthcare organizations and their communities. As part of our celebration, we hosted “40 Days of Giving,” a service-focused challenge encouraging our employees to give back to their communities. Employees were paired into teams and set out on a friendly 40-day competition to see which team could raise the highest combined total of volunteer hours and monetary donations.

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FDA Issues CRL to Avacincaptad Pegol sNDA for Geographic Atrophy

HCPLive

The sNDA was intended to include positive two-year data in the US Prescribing Information for avacincaptad pegol based on the GATHER2 clinical trial.

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What Cardiometabolic Clinicians Can Be Thankful For This Year

Cardiometabolic Health Congress

This year, the cardiometabolic health community has witnessed remarkable advancements. From breakthrough medications to innovative technologies, there is a lot for cardiometabolic clinicians professionals to celebrate. Let’s explore some key developments in 2024 that are offering hope to clinicians and patients. Innovative Therapies and Medications for Cardiometabolic Clinicians Lipid Management and Cardiovascular Therapies : Olezarsen , a new triglyceride-lowering agent, showcased impressive re

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New lessons, from the old chapters of Atrial fibrillation

Dr. S. Venkatesan MD

Atrial fibrillation: Think locally act globally It is clear, except in specific situations like HT, LVH, HFpEF, and other left (or right )sided structural heart diseases, the bulk of the AF is part of systemic destabilization of neuro-metabolic homeostasis. Atria become a poor, jittery victim to a complex interaction of multitude of factors like obesity, systemic inflammation, fatty infiltration, anxiety, abnormal neuro-cardiac modulation, chronic oxygen deprivation. etc.

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Challenges With Current Treatment Options for CSU

HCPLive

Panelists discuss the challenges associated with using biologics for chronic spontaneous urticaria (CSU), including issues related to accessibility and cost, while also explaining why Burton tyrosine kinase (BTK) is considered an ideal target for CSU treatment due to its role in mediating mast cell degranulation.

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Bleeding Risk Using NSAIDs With Anticoagulants After VTE

American College of Cardiology

What is the bleeding risk of nonsteroidal anti-inflammatory drug (NSAID) use in addition to oral anticoagulants (OACs) for the treatment of venous thromboembolism (VTE)?

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Treatment Approaches and the Limitations of Antihistamines for CSU

HCPLive

Panelists discuss how the treatment goals for chronic spontaneous urticaria (CSU) focus on achieving symptom control and improving quality of life for patients, while also aiming for effective management strategies and adherence to treatment plans for physicians.

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Hypoglycemic Events May Trigger Acute Ischemic Stroke Within 30 Days in Those With Diabetes: A Case-Crossover Study

Stroke Journal

Stroke, Ahead of Print. BACKGROUND:Stroke triggers are factors that may precipitate a stroke within a given time interval and can predict the timing of a stroke. While hypoglycemia has been established as a risk factor for cardiovascular events such as acute ischemic stroke (AIS), there is limited research demonstrating hypoglycemic events as stroke triggers.

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Future Landscape of BTK Inhibitors for CSU

HCPLive

Panelists discuss the current and future roles of advanced treatments, including biologics and Bruton tyrosine kinase (BTK) inhibitors, in the management of chronic spontaneous urticaria (CSU), highlighting their potential to improve patient outcomes and the evolving landscape of treatment options.

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Pathophysiology, Diagnosis, and Management of Coronary Artery Disease in the Setting of Atrial Fibrillation

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. Atrial fibrillation (AF) and coronary artery disease are frequently associated and, when so, lead to a grim prognosis. Recent studies suggest the presence of interconnected pathophysiological pathways between the 2 conditions that can promote and aggravate each other, igniting a vicious cycle.

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Steroids and Immunosuppressive Agents for CSU

HCPLive

Panelists discuss how steroids can play a role in the management of chronic spontaneous urticaria (CSU), while emphasizing that practitioners should exercise caution due to potential adverse effects and the need for careful monitoring when using systemic steroids.

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Acute Effects of Cannabis Inhalation on Arterial Stiffness, Vascular Endothelial Function, and Cardiac Function

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundThe cardiovascular impact of cannabis use is incompletely understood. Although evidence links chronic use to an increased risk of disease and adverse cardiovascular events, few studies have investigated the acute effects of cannabis inhalation on subclinical dysfunction. Furthermore, it remains unknown how method of inhalation and cannabinoid profile modify risk.

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J&J Submits sBLA for Guselkumab (Tremfya) Subcutaneous Induction Regimen in UC

HCPLive

The supplemental Biologics License Application is supported by the phase 3 ASTRO study of guselkumab SC induction therapy in ulcerative colitis.

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JACC: CardioOncology Expert Panel Addresses CV Care Before Cancer Treatment

American College of Cardiology

An expert panel report, one of three in a special series published in JACC: CardioOncology, provides a review of the current evidence for the cardiovascular care of patients before cardiotoxic cancer therapy and highlights gaps in the evidence.

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Study Identifies Homelessness as a Predictor Against Clozapine Use

HCPLive

A study identified homelessness and minority status as factors that impact clozapine prescription patterns.

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JACC: CardioOncology Expert Panel Addresses Cardiotoxicity During Cancer Therapy

American College of Cardiology

Preventing, detecting and managing cancer therapy-related cardiovascular toxicity (CTR-CVT) is a clear objective during cancer treatment. An expert panel report published in JACC: CardioOncology provides practical recommendations during cancer therapy supported by high-quality evidence that can be applied across diverse settings, and highlights the significant gaps in knowledge in cardio-oncology.

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FDA Approves Acoramidis (Attruby) for ATTR-CM

HCPLive

With approval, acoramaidis becomes the first agent with a label specifying near-complete stabilization of TTR.

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Consensus on CPR and Emergency CV Care Science: Key Points

American College of Cardiology

The following are key points to remember from an international consensus on cardiopulmonary resuscitation (CPR) and emergency cardiovascular care science with treatment recommendations.

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Medical Ethics Unpacked: Ethical Considerations for Euthanasia & Medical Assistance in Dying

HCPLive

In part 2 of this 2-part discussion, hosts discuss ethical considerations and the growing evidence base around euthanasia and medical assistance in dying.

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Cigarette Smoking And Structural Brain Deficits In Patients With Atrial Fibrillation

The American Journal of Cardiology

Publication date: Available online 21 November 2024 Source: The American Journal of Cardiology Author(s): Raffaele Peter, Stefanie Aeschbacher, Rebecca E. Paladini, Michael Coslovsky, Philipp Krisai, Adrian Schweigler, Tobias Reichlin, Nicolas Rodondi, Andreas Müller, Moa Haller, Merit Röhl, Annina Stauber, Tim Sinnecker, Leo H. Bonati, Thilo Burkard, David Conen, Stefan Osswald, Michael Kühne, Christine S.

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Marcelo Kugelmas, MD: Elafibranor (Iqirvo) Does Not Impact Renal Function in PBC

HCPLive

Kugelmas reviews findings from a secondary analysis of the phase 3 ELATIVE trial suggesting elafibranor is associated with stable kidney function.

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Diagnosis and Prognosis of Isolated Cardiac Sarcoidosis: Multidisciplinary Diagnosis vs Japanese Circulation Society Criteria.

The American Journal of Cardiology

Publication date: Available online 22 November 2024 Source: The American Journal of Cardiology Author(s): Manuel L. Ribeiro Neto, Christine Jellis, Ziad Taimeh, Paul Cremer, Anuhya V. Pulapaka, Allison Wimer, Daniel Rozenbaum, Simran Ganeriwal, Daniel A.

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Gildeuretinol for Stargardt Secures FDA Rare Pediatric, Fast Track Status

HCPLive

FDA grants Rare Pediatric Disease, Fast Track designations to gildeuretinol, aiming to accelerate treatment for Stargardt disease.

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The Congenitally Malformed Aortic Valve in Type A Aortic Dissection: Its Frequency and Consequences

The American Journal of Cardiology

Publication date: Available online 22 November 2024 Source: The American Journal of Cardiology Author(s): Kyle A. McCullough, John B. Eisenga, J. Michael DiMaio, Charles S.

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John Tesser, MD: Improving Outcomes in RA With Vagus Nerve Stimulation

HCPLive

Tesser discussed the background of the phase 3 RESET-RA trial and efficacy findings.

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Untangling RV-PA Coupling and PH Definitions in TEER

The American Journal of Cardiology

Publication date: Available online 22 November 2024 Source: The American Journal of Cardiology Author(s): Kyeeun Park, Houman Khalili

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Real-World Study Confirms Similar Efficacy of Guselkumab and IL-17i for PsA

HCPLive

Findings from PsABIOnd can help reassure clinicians of similar efficacy between treatment choices.

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Genetic Determinants of Prosthetic Valve Thrombosis: Paving the Way for Personalized Anticoagulation

The American Journal of Cardiology

Publication date: Available online 22 November 2024 Source: The American Journal of Cardiology Author(s): Rahul Chaudhary, Matthew E.

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To Lower Stroke Risk in Patients Undergoing Atrial Fibrillation Ablation, Is a Device or a Medication Better?

NEJM Journal Watch - Cardiology

Closure of the atrial appendage was superior to oral anticoagulation in safety and noninferior in effectiveness.