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Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post. Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
(MedPage Today) -- Uptake of continuous glucose monitoring (CGM) was relatively low among vulnerable diabetes patients in the largest national system of safety-net primary care clinics, a retrospective cross-sectional study found. In patients.
A new study found that prolonged standing at work had a negative impact on the research participants' 24-hour blood pressure. In contrast, spending more time sitting at work was associated with better blood pressure. The study suggests that activity behavior during working hours may be more relevant to 24-hour blood pressure than recreational physical activity.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Researchers at Penn State are using machine learning and existing electrocardiogram (ECG) data to help doctors make more accurate predictions. A team of artificial intelligence engineers, in collaboration with a team of physicians from Penn State Heart and Vascular Institute, is working to develop novel algorithms for point-of-care, in-house use and for technology licensing.
Preventing, detecting and managing cancer therapy-related cardiovascular toxicity (CTR-CVT) is a clear objective during cancer treatment. An expert panel report published in JACC: CardioOncology provides practical recommendations during cancer therapy supported by high-quality evidence that can be applied across diverse settings, and highlights the significant gaps in knowledge in cardio-oncology.
Preventing, detecting and managing cancer therapy-related cardiovascular toxicity (CTR-CVT) is a clear objective during cancer treatment. An expert panel report published in JACC: CardioOncology provides practical recommendations during cancer therapy supported by high-quality evidence that can be applied across diverse settings, and highlights the significant gaps in knowledge in cardio-oncology.
If someone's heart suddenly stops beating, they may only have minutes to live. Doing CPR (cardiopulmonary resuscitation) can increase their chances of survival. CPR makes sure blood keeps pumping, providing oxygen to the brain and vital organs until specialist treatment arrives.
Following the publication of the new RLS recommendations, HCPLive spoke with John Winkelman, MD, PhD, chair of the AASM committee that revised the guidelines.
Journal of the American Heart Association, Ahead of Print. BackgroundThe cardiovascular impact of cannabis use is incompletely understood. Although evidence links chronic use to an increased risk of disease and adverse cardiovascular events, few studies have investigated the acute effects of cannabis inhalation on subclinical dysfunction. Furthermore, it remains unknown how method of inhalation and cannabinoid profile modify risk.
This meta-analysis showed that both secondary closure techniques substantially reduce the risk of hidradenitis suppurativa recurrence compared to primary direct closure.
Journal of the American Heart Association, Ahead of Print. Atrial fibrillation (AF) and coronary artery disease are frequently associated and, when so, lead to a grim prognosis. Recent studies suggest the presence of interconnected pathophysiological pathways between the 2 conditions that can promote and aggravate each other, igniting a vicious cycle.
Stroke, Ahead of Print. BACKGROUND:Stroke triggers are factors that may precipitate a stroke within a given time interval and can predict the timing of a stroke. While hypoglycemia has been established as a risk factor for cardiovascular events such as acute ischemic stroke (AIS), there is limited research demonstrating hypoglycemic events as stroke triggers.
An expert panel report, one of three in a special series published in JACC: CardioOncology, provides a review of the current evidence for the cardiovascular care of patients before cardiotoxic cancer therapy and highlights gaps in the evidence.
In this analysis, the investigators systematically assessed links between the macronutrient profiles of common allergenic foods and corresponding prevalence of food allergy.
A Finnish study found that prolonged standing at work had a negative impact on the research participants' 24-hour blood pressure. In contrast, spending more time sitting at work was associated with better blood pressure.
What is the bleeding risk of nonsteroidal anti-inflammatory drug (NSAID) use in addition to oral anticoagulants (OACs) for the treatment of venous thromboembolism (VTE)?
The following are key points to remember from an international consensus on cardiopulmonary resuscitation (CPR) and emergency cardiovascular care science with treatment recommendations.
In part 2 of this 2-part discussion, hosts discuss ethical considerations and the growing evidence base around euthanasia and medical assistance in dying.
Abstract Gene therapy has recently become a reality in the treatment of cardiovascular diseases. Strategies to modulate gene expression using antisense oligonucleotides or small interfering RNA are proving to be safe and effective in the clinic. Adeno-associated viral vector-based gene delivery and CRISPR-Cas9-based genome editing have emerged as efficient strategies for gene delivery and repair in humans.
Panelists discuss the challenges associated with using biologics for chronic spontaneous urticaria (CSU), including issues related to accessibility and cost, while also explaining why Burton tyrosine kinase (BTK) is considered an ideal target for CSU treatment due to its role in mediating mast cell degranulation.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundGlyceryl trinitrate (GTN), also known as nitroglycerin, is predominantly recognized as a vasodilator for ischemic heart disease, and its potential neuroprotective properties in acute ischemic stroke remain under exploration. We sought to discover the therapeutic advantages and mechanisms of postrecanalization GTN administration in acute ischemic stroke.Methods and ResultsA total of 118 male SpragueDawle
Panelists discuss how the treatment goals for chronic spontaneous urticaria (CSU) focus on achieving symptom control and improving quality of life for patients, while also aiming for effective management strategies and adherence to treatment plans for physicians.
ABSTRACT Introduction Substernal extravascular defibrillators (EV ICDs) have been shown to be effective and safe for patients at risk of sudden cardiac death, however, there is little evidence around the safety of extracting chronic devices. Methods and Results We present a 50-year-old patient in whom a Medtronic EV ICD system was successfully removed without specialist extraction tools, 186 weeks after implantation, by an operator experienced in transvenous lead extraction but without formal tr
Panelists discuss the current and future roles of advanced treatments, including biologics and Bruton tyrosine kinase (BTK) inhibitors, in the management of chronic spontaneous urticaria (CSU), highlighting their potential to improve patient outcomes and the evolving landscape of treatment options.
Panelists discuss how steroids can play a role in the management of chronic spontaneous urticaria (CSU), while emphasizing that practitioners should exercise caution due to potential adverse effects and the need for careful monitoring when using systemic steroids.
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