Fri.Nov 08, 2024

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Midlife Choices May Offset Genetic Risk for Dementia, Stroke, Late-Life Depression

Med Page Today

(MedPage Today) -- Healthier lifestyle behaviors in midlife were linked with better outcomes in people with genetic predisposition for age-related brain diseases, longitudinal data from the U.K. Biobank showed. Over about 12 years of follow-up.

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Should You Take A Statin To Lower Your Cholesterol?

Dr. Paddy Barrett

Let’s start with the fact that this is not a yes or no answer. To answer this question, you need to understand three key factors: What is your baseline risk? Over what time horizon are you looking to reduce risk? What is your attitude toward reducing that risk? Only when you have a clear idea of those three factors can you decide whether or not to take a medication to lower your LDL cholesterol.

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FDA Adds New Warning to GLP-1 Drugs

Med Page Today

(MedPage Today) -- Labels of all GLP-1 receptor agonists now carry a warning about pulmonary aspiration during general anesthesia or deep sedation. The warning affects all treatments containing GLP-1 receptor agonists, including semaglutide (Ozempic.

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Role of Testing in CSU Diagnosis

HCPLive

Panelists discuss the recommended diagnostic testing for chronic spontaneous urticaria (CSU), noting that extensive testing is not necessary and that routine blood counts, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), IgG anti-thyroid peroxidase (TPO), and total IgE are adequate, while also addressing the limited role of biopsy; they further explore how disease severity is assessed using tools like Urticaria Activity Score (UAS7) and Urticaria Control Test (UCT).

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Patients With Obesity Shed Pounds With Drug-Free Capsule

Med Page Today

(MedPage Today) -- SAN ANTONIO -- Use of an oral biodegradable drug-free capsule led to more weight loss among patients with overweight or obesity compared with placebo, according to the randomized RESET trial. Among 279 patients, mean change.

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Dog-owner interaction is reflected in heart rate variability

Science Daily - Heart Disease

A recent study showed that the heart rate variability of a dog and its owner adapt to each other during interaction. High heart rate variability is associated with relaxation, while low heart rate variability indicates stimulation. The study deepens our understanding of the emotional connection between a dog and its owner, including its underlying physiological mechanisms.

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Nurse's Death Tied to GLP-1 Drug; Research Monkey Jailbreak; Congressman Has Cancer

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Diabetes and weight-loss drug tirzepatide (Mounjaro, Zepbound) was listed as a contributing factor in the death of a 58-year-old nurse from Scotland who died of.

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Baseline wander. But what else do you see?

Dr. Smith's ECG Blog

Written by Magnus Nossen The below ECG was obtained from a 65 year old man with ongoing chest pain. He has a history of hypertension an d tobacco use. He is otherwise healthy. There is no prior ECG for comparison. What do you think? ECG #1 Interpretation: The quality of the above ECG is not optimal. There is significant baseline wander that does make it more challenging to interpret ischemic changes.

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Examining the clinical role and educational preparation of heart failure nurses across Europe. A survey of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) and the Association of Cardiovascular Nursing and Allied Professions (ACNAP) of the ESC

European Journal of Heart Failure

The clinical role and educational preparation of heart failure nurses across Europe. HF, heart failure; HFN, heart failure nurse; MDT, multidisciplinary team. Aims To describe the clinical practice and educational preparation of heart failure (HF) nurses across Europe and determine the key differences between countries. Methods and results A survey tool was developed, in English, by the Heart Failure Association Patient Care committee of the European Society of Cardiology (ESC).

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LimFlow Limits Limb-Threatening Ischemia

CardiacWire

Late-breaking second year results from the PROMISE II trial showed that the LimFlow system achieved strong outcomes for avoiding amputations and promoting limb salvage among “no-option” patients with chronic limb-threatening ischemia (CLTI). The LimFlow system consists of several products designed to optimize blood flow in critically ischemic feet by facilitating revascularization.

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Physiology Friday #243: Brief Activity Bouts Throughout the Day Make Sedentary Behavior Less Risky

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. “Sitting is the new smoking” is a metaphor that I once found to be hyperbolic.

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Multimodality Imaging in Cardiac Masses: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the-art review on multimodality imaging in the diagnostic work-up of patients with cardiac masses.

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Tool Used to Assess Parents’ Management of Child Anaphylaxis, Autoinjector Administration

HCPLive

The Parental Self-efficacy in Managing Anaphylaxis (PSEMA) questionnaire was shown to be effective in assessing self-efficacy of parents in managing their childrens’ conditions.

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Risk of MI After Pregnancy With Hypertension

American College of Cardiology

What is the anatomy of coronary arteries and the type of coronary artery lesions in women with a history of hypertensive disorders of pregnancy (HDP)?

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Philips Enrolls First Patient in Clinical Trial for Integrated Single-Device to Treat PAD

DAIC

tim.hodson Fri, 11/08/2024 - 13:23 Nov. 4, 2024 — Royal Philips recently announced enrollment of the first patient in the U.S. THOR IDE clinical trial, which will study an innovative combined laser atherectomy and intravascular lithotripsy catheter that integrates two critical PAD treatments into a single device. Procedures that previously required the use of two different devices can now be performed in a single procedure using a single device, simplifying workflows and procedures and potential

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ECU Health leader named cardiology group president

Becker's Hospital Review - Cardiology

Greenville, N.C.-based ECU Health's director of cardiovascular disease management services, Stacey Greenway, was appointed president of the American Association of Cardiovascular and Pulmonary Rehabilitation.

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MASH and Cardiometabolic Health: Pharmacotherapy and Emerging Therapies (Part 2)

Cardiometabolic Health Congress

In Part 1 , we explored the foundational elements of MASH management, including lifestyle modifications and initial assessments. In this post, we’ll focus on pharmacotherapy, emerging strategies, and practical treatments for managing MASH in patients with cardiometabolic conditions. Pharmacotherapy for Cardiometabolic and Liver Health Medications that target both metabolic and liver health are critical for managing MASH.

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Medtronic Releases Atherectomy Studies at VIVA 2024

DAIC

tim.hodson Fri, 11/08/2024 - 10:10 Medtronic recently announced results from two studies evaluating the utility of atherectomy for peripheral endovascular interventions. Results from both analyses were released at the Vascular InterVentional Advances (VIVA) 2024 conference in Las Vegas. The Total REALITY study retrospectively compared directional atherectomy (DA) versus balloon predilatation prior to drug-coated balloon (DCB) treatment of long, calcified femoropopliteal lesions.

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Surgeons and Cardiologists Reconcile Over Coronary Revascularization Guidelines at EACTS 2024

Society of Thoracic Surgeons - Congenital

At the 2024 European Association for Cardio-Thoracic Surgery (EACTS) meeting in Lisbon, Portugal, leaders in cardiac surgery and interventional cardiology came together, signaling a newfound harmony over coronary revascularization practices for complex heart conditions. This session marked a significant change from the intense disagreements that followed the EXCEL trial controversy five years ago, which raised concerns about data interpretation in revascularization treatments for left main disea

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Tips on Diagnosing CSU

HCPLive

Panelists discuss how the diagnosis of chronic spontaneous urticaria (CSU) involves assessing wheals, hives, and angioedema, while emphasizing that the chronic and spontaneous nature of the condition can complicate the diagnostic process.

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Aortic-Valve Replacement vs. Clinical Surveillance for Asymptomatic Severe Aortic Stenosis

NEJM Journal Watch - Cardiology

A strategy of early AVR was superior to clinical surveillance due to a reduction in hospitalizations.

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Referring CSU Patients to a Specialist

HCPLive

Panelists discuss the appropriate timing for general practitioners to refer patients with chronic spontaneous urticaria (CSU) to specialists, examining real-world referral patterns and the dynamics between dermatologists and allergists in managing the condition.

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The cancer-cardiology connection: 6 takeaways

Becker's Hospital Review - Cardiology

The annual Global Cardio-Oncology Summit was held in September, bringing together healthcare professionals in the context of cardiovascular disease and cancer.

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Less Is More: Diagnostic Testing for CSU

HCPLive

Panelists discuss how testing for chronic spontaneous urticaria (CSU) is recommended, with routine blood counts, including tests for erythrocyte sedimentation rate (ESR) and/or c-reactive protein (CRP), and specific antibody tests such as immunoglobulin G (IgG) anti- thyroid peroxidase (TPO) and total immunoglobulin E (IgE) being highlighted, according to guidelines.

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ACC Practice Made Perfect: Precision Planning: Developing Sub-Specialty Strategies in Action

American College of Cardiology

Welcome to the Cardiovascular (CV) Dyad Leadership Strategic Planning Series! In episode three of four, Ms. Amy Brownell will interview Ms. Corrin McCloskey and Dr. Joseph Goeke on developing a strategic plan for sub-specialty programs with the CV Service Line.

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Akif Shameem, MD: Generalized Anxiety Disorder Linked to Longer Hospitals in Children with IBD

HCPLive

At NASPGHAN 2024, HCPLive spoke to Shameem about his study on inpatient outcomes of pediatric patients with IBD and GAD vs patients without GAD.

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Outcomes After Transseptal MViV Replacement

American College of Cardiology

What are the contemporary outcomes for patients undergoing transseptal SAPIEN 3/SAPIEN 3 Ultra transcatheter mitral valve-in-valve (MViV) replacement?

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Novel Gas-Sensing Capsule May Provide New Tool for Assessing Motility Disorders

HCPLive

Braden Kuo, MD, explains how the gas-sensing capsule compares to the FDA-cleared, but now discontinued, SmartPill wireless motility capsule.

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CMS Grants Distinct TPT Device Code and Category to Recor Medical for Ultrasound Renal Denervation

DAIC

tim.hodson Fri, 11/08/2024 - 09:57 Nov. 1, 2024 — Recor Medical, Inc. and its parent company, Otsuka Medical Devices Co. recently announced U.S. Centers for Medicare & Medicaid Services (CMS) have granted the company’s Paradise Ultrasound Renal Denervation system a Transitional Pass-through (TPT) payment. The approval of TPT offers incremental reimbursement payments for outpatient procedures performed with ultrasound renal denervation for Medicare fee-for-service beneficiaries.

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2 New Studies Highlight Issues with Treatment of Anaphylaxis

HCPLive

In recent findings presented at ACAAI 2024, patients, caregivers, and even emergency medical professionals were shown to face issues with regard to treatment of anaphylaxis reactions.

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AI machines are hot & hungry : Let us learn, teach, and train them in cardiology

Dr. S. Venkatesan MD

This is a transcript of one such conversation with an AI engine Llama 3.2 version by Meta , (You may call it learning, teaching , training or whatever). It is a long read, meant only for those who want to know the hidden intricacies in the concept of “Time window” in STEMI and its important Implication in patient care. [08/11, 12:07] Dr S Venkatesan: Is the therapeutic time window for primary PCI and thrombolysis same ?

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EoE KIDS Suggests Dupilumab Offers Benefit Regardless of Prior Therapy Exposure

HCPLive

Post-hoc analysis of EoE KIDS trial shows dupilumab benefits for pediatric eosinophilic esophagitis, effective in patients with prior therapy limitations.

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Secondary Hypertension in Young Adults

NEJM Journal Watch - Cardiology

Patients in their 30s had higher rates of secondary hypertension than did younger adults, which highlights potential gaps in screening recommendations.

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Functional Exercise Training Reduced Pain in People With Fibromyalgia

HCPLive

The pain reduction effects did not last long beyond the scope of the trial, underscoring the importance of continuing such exercises.

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Don’t make false enemies in medical practice

Dr. S. Venkatesan MD

Visit the post for more.

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SGLT-2 Inhibitors May be Beneficial in People With Kidney Stones and Gout

HCPLive

SGLT-2 inhibitors had more protective effects than GLP-1 receptor agonists or DPP-4 inhibitors in this population.

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