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Let’s start with the fact that this is not a yes or no answer. To answer this question, you need to understand three key factors: What is your baseline risk? Over what time horizon are you looking to reduce risk? What is your attitude toward reducing that risk? Only when you have a clear idea of those three factors can you decide whether or not to take a medication to lower your LDL cholesterol.
Late-breaking second year results from the PROMISE II trial showed that the LimFlow system achieved strong outcomes for avoiding amputations and promoting limb salvage among “no-option” patients with chronic limb-threatening ischemia (CLTI). The LimFlow system consists of several products designed to optimize blood flow in critically ischemic feet by facilitating revascularization.
tim.hodson Fri, 11/08/2024 - 13:23 Nov. 4, 2024 — Royal Philips recently announced enrollment of the first patient in the U.S. THOR IDE clinical trial, which will study an innovative combined laser atherectomy and intravascular lithotripsy catheter that integrates two critical PAD treatments into a single device. Procedures that previously required the use of two different devices can now be performed in a single procedure using a single device, simplifying workflows and procedures and potential
(MedPage Today) -- Healthier lifestyle behaviors in midlife were linked with better outcomes in people with genetic predisposition for age-related brain diseases, longitudinal data from the U.K. Biobank showed. Over about 12 years of follow-up.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
tim.hodson Fri, 11/08/2024 - 10:10 Medtronic recently announced results from two studies evaluating the utility of atherectomy for peripheral endovascular interventions. Results from both analyses were released at the Vascular InterVentional Advances (VIVA) 2024 conference in Las Vegas. The Total REALITY study retrospectively compared directional atherectomy (DA) versus balloon predilatation prior to drug-coated balloon (DCB) treatment of long, calcified femoropopliteal lesions.
(MedPage Today) -- Labels of all GLP-1 receptor agonists now carry a warning about pulmonary aspiration during general anesthesia or deep sedation. The warning affects all treatments containing GLP-1 receptor agonists, including semaglutide (Ozempic.
At the 2024 European Association for Cardio-Thoracic Surgery (EACTS) meeting in Lisbon, Portugal, leaders in cardiac surgery and interventional cardiology came together, signaling a newfound harmony over coronary revascularization practices for complex heart conditions. This session marked a significant change from the intense disagreements that followed the EXCEL trial controversy five years ago, which raised concerns about data interpretation in revascularization treatments for left main disea
At the 2024 European Association for Cardio-Thoracic Surgery (EACTS) meeting in Lisbon, Portugal, leaders in cardiac surgery and interventional cardiology came together, signaling a newfound harmony over coronary revascularization practices for complex heart conditions. This session marked a significant change from the intense disagreements that followed the EXCEL trial controversy five years ago, which raised concerns about data interpretation in revascularization treatments for left main disea
(MedPage Today) -- SAN ANTONIO -- Use of an oral biodegradable drug-free capsule led to more weight loss among patients with overweight or obesity compared with placebo, according to the randomized RESET trial. Among 279 patients, mean change.
A recent study showed that the heart rate variability of a dog and its owner adapt to each other during interaction. High heart rate variability is associated with relaxation, while low heart rate variability indicates stimulation. The study deepens our understanding of the emotional connection between a dog and its owner, including its underlying physiological mechanisms.
(MedPage Today) -- Note that some links may require registration or subscription. Diabetes and weight-loss drug tirzepatide (Mounjaro, Zepbound) was listed as a contributing factor in the death of a 58-year-old nurse from Scotland who died of.
tim.hodson Fri, 11/08/2024 - 09:57 Nov. 1, 2024 — Recor Medical, Inc. and its parent company, Otsuka Medical Devices Co. recently announced U.S. Centers for Medicare & Medicaid Services (CMS) have granted the company’s Paradise Ultrasound Renal Denervation system a Transitional Pass-through (TPT) payment. The approval of TPT offers incremental reimbursement payments for outpatient procedures performed with ultrasound renal denervation for Medicare fee-for-service beneficiaries.
The clinical role and educational preparation of heart failure nurses across Europe. HF, heart failure; HFN, heart failure nurse; MDT, multidisciplinary team. Aims To describe the clinical practice and educational preparation of heart failure (HF) nurses across Europe and determine the key differences between countries. Methods and results A survey tool was developed, in English, by the Heart Failure Association Patient Care committee of the European Society of Cardiology (ESC).
The following are key points to remember from a state-of-the-art review on multimodality imaging in the diagnostic work-up of patients with cardiac masses.
The annual Global Cardio-Oncology Summit was held in September, bringing together healthcare professionals in the context of cardiovascular disease and cancer.
The Parental Self-efficacy in Managing Anaphylaxis (PSEMA) questionnaire was shown to be effective in assessing self-efficacy of parents in managing their childrens’ conditions.
Greenville, N.C.-based ECU Health's director of cardiovascular disease management services, Stacey Greenway, was appointed president of the American Association of Cardiovascular and Pulmonary Rehabilitation.
Post-hoc analysis of EoE KIDS trial shows dupilumab benefits for pediatric eosinophilic esophagitis, effective in patients with prior therapy limitations.
Circulation, Ahead of Print. BACKGROUND:Patients with hypertrophic cardiomyopathy without left ventricular outflow tract obstruction commonly experience reduced exercise capacity. Physical training improves exercise capacity in these patients, but whether the underlying effects of exercise are a result of central hemodynamic or peripheral improvement is unclear.
Welcome to the Cardiovascular (CV) Dyad Leadership Strategic Planning Series! In episode three of four, Ms. Amy Brownell will interview Ms. Corrin McCloskey and Dr. Joseph Goeke on developing a strategic plan for sub-specialty programs with the CV Service Line.
Panelists discuss how the diagnosis of chronic spontaneous urticaria (CSU) involves assessing wheals, hives, and angioedema, while emphasizing that the chronic and spontaneous nature of the condition can complicate the diagnostic process.
Panelists discuss the appropriate timing for general practitioners to refer patients with chronic spontaneous urticaria (CSU) to specialists, examining real-world referral patterns and the dynamics between dermatologists and allergists in managing the condition.
Panelists discuss how testing for chronic spontaneous urticaria (CSU) is recommended, with routine blood counts, including tests for erythrocyte sedimentation rate (ESR) and/or c-reactive protein (CRP), and specific antibody tests such as immunoglobulin G (IgG) anti- thyroid peroxidase (TPO) and total immunoglobulin E (IgE) being highlighted, according to guidelines.
In recent findings presented at ACAAI 2024, patients, caregivers, and even emergency medical professionals were shown to face issues with regard to treatment of anaphylaxis reactions.
Circulation: Heart Failure, Volume 17, Issue 12 , Page e011761, December 1, 2024. BACKGROUND:Cardiorenal dysfunction with impaired cyclic GMP (cGMP) response is common in patients presenting with acute heart failure (HF). Type V phosphodiesterase (PDEV) is known to be upregulated in HF and may explain the dysfunction of renal response. The aim of this study was to determine whether B-type natriuretic peptide (BNP) alone or in combination with PDEV inhibition improves renal function and increases
We analyzed scar formation following ethanol infusion into the vein of Marshall (EI-VOM), and its impact on left atrium (LA) function. EI-VOM produced persistent scarring detected by LGE-CMR at the 3-month follow-up. LGE-CMR scarring involved the whole VOM trajectory. LA volume was reduced after ablation, without significant changes in LA functional parameters.
Circulation: Heart Failure, Volume 17, Issue 12 , Page e011729, December 1, 2024. BACKGROUND:Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that blockade of IL1RAP (IL-1 receptor accessory protein), a shared subunit of the IL-1, IL-33, and IL-36 receptors, could be more efficient than IL-1 blockade alone.METHODS:We induced coxsackievirus B3 (CVB3)mediat
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