Wed.Feb 28, 2024

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Cannabis use linked to increase in heart attack and stroke risk

American Heart News - Heart News

Research Highlights: An analysis of survey data for 430,000 adults in the U.S. found that using cannabis has a significant association with an increased risk of heart attack and stroke, independent of tobacco use, with higher odds among the adults.

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World's best cardiology hospitals, per Newsweek

Becker's Hospital Review - Cardiology

Discover the top 10 cardiology hospitals in the world, with seven based in the U.S. according to Newsweek's 2024 "World's Best Hospitals" list.

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Abdominal Fat and Dementia; Mask Ban Lawsuit Tossed; FDA Rejects Psych Drug

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. In middle-age men with high Alzheimer's dementia risk, higher pancreatic fat was linked with lower cognition and brain volumes. (Obesity) The Department of Justice.

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Urgent Need to Develop Best Practices to Advance Use of AI in Cardiovascular Care

DAIC

Getty Images milla1cf Wed, 02/28/2024 - 19:13 February 28, 2024 — Artificial intelligence ( AI ) may transform cardiovascular medicine. For now, though, many challenges remain, and few AI tools have been proven to improve care, according to a new American Heart Association scientific statement published today in Circulation , the Association’s flagship, peer-reviewed journal.

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Smartphone App with AI Detects Depression Onset from Facial Expressions

HCPLive

MoodCapture, an app with AI that can detect depression onset from facial cues, accurately diagnosed 75% of participants in a study with early symptoms of depression.

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Long-term Survivors of Childhood Cancer at Higher Risk of Death Following Heart Issues; Threshold for Treating Risk Factors Should be Lower

DAIC

Wendy Bottinor, MD. Image courtesy of VCU Massey Comprehensive Cancer Center milla1cf Wed, 02/28/2024 - 19:24 February 28, 2024 — New research out of VCU Massey Comprehensive Cancer Center and VCU Health Pauley Heart Center indicates that survivors of childhood cancer are at a significantly higher risk of death following a major cardiovascular event — including heart failure , heart attack or stroke — than the general public.

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Melanoma Screening Delays During Lockdowns Linked to Deaths, Significant Economic Cost

HCPLive

This analysis emphasizes the necessity of prevention of melanoma as well as the public health and economic consequences of patients’ delaying of skin cancer diagnoses.

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The Risks and Benefits of 'Too Much' Exercise

Physiologically Speaking

Athens, Greece September 12, 490 BCE This is the site of the first known fatality related to endurance running. Upon arrival to Athens, running the now-revered distance of 26 miles (and change) to deliver a message of a military victory against the Persians, Pheidippides, our Greek hero, collapsed, most likely due to sheer exhaustion on behalf of his previous effort. “Joy to you, we’ve won” he said, and there and then he died, breathing his last breath with the words “Joy

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Cannabis use linked to increase in heart attack and stroke risk

Science Daily - Heart Disease

More frequent use of cannabis was associated with higher odds of adverse cardiovascular outcomes, finds new study.

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Use of Artificial Intelligence in Improving Outcomes in Heart Disease: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. A major focus of academia, industry, and global governmental agencies is to develop and apply artificial intelligence and other advanced analytical tools to transform health care delivery. The American Heart Association supports the creation of tools and services that would further the science and practice of precision medicine by enabling more precise approaches to cardiovascular and stroke research, prevention, and care of individuals and populations.

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VK2735, a Dual GLP-1/GIP RA, Showcases Weight Loss Effects in Phase 2 Trial

HCPLive

Viking Therapeutics' dual GLP-1/GIP receptor agonist VK2735 showed promising weight reduction in the phase 2 VENTURE trial, with the 15 mg dose contributing to a 14% reduction in body weight from baseline to week 13.

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Association of Cannabis Use With Cardiovascular Outcomes Among US Adults

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundWe examined the association between cannabis use and cardiovascular outcomes among the general population, among never‐tobacco smokers, and among younger individuals.Methods and ResultsThis is a population‐based, cross‐sectional study of 2016 to 2020 data from the Behavioral Risk Factor Surveillance Survey from 27 American states and 2 territories.

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Cardiac Rehabilitation — Challenges, Advances, and the Road Ahead

The New England Journal of Medicine

Cardiac rehabilitation provides evidence-based, secondary prevention after a cardiovascular event. This review addresses the benefits of cardiac rehabilitation programs and current barriers to participation.

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Navigating P2Y12 inhibition in the labyrinth of cardio-oncology care: cangrelor bridging in patients with cancer

Frontiers in Cardiovascular Medicine

Cangrelor, a potent intravenous P2Y12 platelet inhibitor, has demonstrated effectiveness in reducing ischemic events without a corresponding increase in severe bleeding during percutaneous coronary intervention, as evidenced by the CHAMPION-PHOENIX trial. Its off-label role as a bridging antiplatelet agent for patients facing high thrombotic risks who must temporarily stop oral P2Y12 inhibitor therapy further underscores its clinical utility.

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Urgent need to develop best practices to advance use of AI in cardiovascular care

American Heart News - Heart News

Statement Highlights: The American Heart Association encourages research and development of artificial intelligence (AI) and other related tools and services that may support and enable more precise approaches to cardiovascular and stroke research,

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AF and Guideline-Directed Therapy in HF: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the-art review on implications of atrial fibrillation (AF) for guideline-directed therapy in patients with heart failure (HF):

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Imagenetics for Precision Medicine in Dilated Cardiomyopathy

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Ahead of Print. Dilated cardiomyopathy (DCM) is a common heart muscle disorder of nonischemic etiology associated with heart failure development and the risk of malignant ventricular arrhythmias and sudden cardiac death. A tailored approach to risk stratification and prevention of sudden cardiac death is required in genetic DCM given its variable presentation and phenotypic severity.

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Comparative efficacy of anthropometric indices in predicting 10-year ASCVD risk: insights from NHANES data

Frontiers in Cardiovascular Medicine

Background Cardiovascular diseases remain a leading cause of morbidity and mortality worldwide. Accurately predicting the 10-year risk of Atherosclerotic Cardiovascular Disease (ASCVD) is crucial for timely intervention and management. This study aimed to evaluate the predictive performance of six anthropometric indices in assessing the 10-year ASCVD risk.

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Remission Rates Similar Among Patients with RA Receiving Adalimumab, Other Biologics

HCPLive

No statistically significant differences in the odds of remission at ≤12 months were observed between patients receiving adalimumab compared with other biologics.

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Prediction of intraoperative red blood cell transfusion in valve replacement surgery: machine learning algorithm development based on non-anemic cohort

Frontiers in Cardiovascular Medicine

Background Our study aimed to develop machine learning algorithms capable of predicting red blood cell (RBC) transfusion during valve replacement surgery based on a preoperative dataset of the non-anemic cohort. Methods A total of 423 patients who underwent valvular replacement surgery from January 2015 to December 2020 were enrolled. A comprehensive database that incorporated demographic characteristics, clinical conditions, and results of preoperative biochemistry tests was used for establishi

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The SGLT2 inhibitor Empagliflozin promotes post-stroke functional recovery in diabetic mice

Cardiovascular Diabetology

Type-2 diabetes (T2D) worsens stroke recovery, amplifying post-stroke disabilities. Currently, there are no therapies targeting this important clinical problem. Sodium-glucose cotransporter 2 inhibitors (SGLT2.

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Lipoprotein(a)’s High (and Uneven) Cardiovascular Risks

CardiacWire

Harvard researchers strengthened the link between high Lipoprotein(a) levels and greater risks of future cardiovascular events, including among patients who haven’t been diagnosed with ASCVD. The researchers analyzed 12-year outcomes from 16,419 people in the Mass General Brigham Lp(a) Registry who had their Lp(a) measured between 2000 to 2019, including 62% with a history of ASCVD (prior MI, revascularization, ischemic stroke).

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Effects of different traditional Chinese exercise in the treatment of essential hypertension: a systematic review and network meta-analysis

Frontiers in Cardiovascular Medicine

Background As a therapy to prevent and treat essential hypertension (EH), traditional Chinese exercises (TCEs) were widely used in clinical practice. However, there is a lack of strictly comparison of the antihypertensive efficacy of different TCEs, which not conducive to the selection of the best and most optimal treatment. This study aimed to perform a network meta-analysis to objectively evaluate which TCE has the best effects in assisting with lowering blood pressure.

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FDA Accepts sBLA of Bimekizumab for 3 New Indications Including Psoriatic Arthritis

HCPLive

This announcement by UCB follows the results of four phase 3 studies on the use of bimekizumab for PsA, ankylosing spondylitis, and non-radiographic axial spondyloarthritis.

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Physician-Optimized Postpartum Hypertension Treatment

American College of Cardiology

The goal of the secondary analysis of the POP-HT trial was to determine the effect on cardiac remodeling of intensive, telehealth-based management of hypertension (HTN) versus usual postpartum care following hypertensive pregnancy.

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Study IDs 6 Blood Biomarkers for Predicting Cardiovascular Disease in Rheumatoid Arthritis

HCPLive

A study from Brigham and Women's Hospital has identified 6 blood-based biomarkers that may predict cardiovascular disease risk in rheumatoid arthritis patients.

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Vest can detect earlier signs of heart muscle disease

Science Daily - Heart Disease

A reusable vest that can map the electric impulses of the heart in fine detail could detect abnormalities from a potentially fatal heart disease much earlier than is currently possible, a new study suggests.

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Nonmedical Switch to Infliximab Biosimilar Safe, Linked to Cost Savings in Children with IBD

HCPLive

Inflammatory markers, infliximab levels, and physician global assessment scores remained similar when assessed pre- and post-switch to an infliximab biosimilar.

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Philips Appoints Charlotte Hanneman to succeed Abhijit Bhattacharya as Chief Financial Officer (CFO)

DAIC

Health technology giant Royal Philips has announced its proposal to appoint Charlotte Hanneman as member of the Board of Management to fulfill the role of Chief Financial Officer (CFO), filling the position held by Abhijit Bhattacharya, who will be retiring at the end of September after in that role since 2015. Image courtesy: Royal Philips christine.book Wed, 02/28/2024 - 11:30 February 28, 2024 — Royal Philips has announced the proposal to appoint Charlotte Hanneman as member of the Board of M

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Diabetes Dialogue: Understanding MARD, Comparing Popular CGM Sensors

HCPLive

Hosts breakdown a pair of recent publications related to better understanding the strengths and limitations of MARD as well as a study comparing the Dexcom G7 and FreeStyle Libre 3 sensors.

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A Closer Look at ECMO & VAD in Honor of American Heart Month

CTVS

February is American Heart Month and we are highlighting some of the important therapies we work with often to aid in repairing and/or extend the life of the heart. Our board-certified cardiothoracic surgeons perform procedures day in and day out to improve heart health and save lives. Some of these include administering technologies such as ECMO and VAD.

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A Patient-Centric Medcast on the Journey Through Moderate Plaque Psoriasis

HCPLive

Advanced practice providers in dermatology discuss exciting developments in the treatment landscape of plaque psoriasis. Listen to their insights into the often-challenging journey patients go on. The arrival of novel oral systemic treatment options offers opportunities to alleviate the burden of this chronic disease.

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Characteristics of pulmonary artery strain assessed by cardiovascular magnetic resonance imaging and associations with metabolomic pathways in human ageing

Frontiers in Cardiovascular Medicine

Background Pulmonary artery (PA) strain is associated with structural and functional alterations of the vessel and is an independent predictor of cardiovascular events. The relationship of PA strain to metabolomics in participants without cardiovascular disease is unknown. Methods In the current study, community-based older adults, without known cardiovascular disease, underwent simultaneous cine cardiovascular magnetic resonance (CMR) imaging, clinical examination, and serum sampling.

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Patients with RA View Text Message Platform as Supportive Tool for Care

HCPLive

Patients perceived WelTel as a beneficial tool for providing quality care across domains including efficiency, safety, and patient-centeredness.

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Eagle’s Eye View: ASCVD Risk and Diabetes, TRI-SCORE, Severe Tricuspid Regurgitation, COVID Boosters and Myocarditis

American College of Cardiology

In this week’s View, Dr. Eagle covers coronary calcium scores and how they predict ASCVD risk in the presence of left main disease and diabetes.

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Guselkumab Improves Work Productivity, Daily Activity in Psoriatic Arthritis

HCPLive

In an analysis of the DISCOVER-2 trial, guselkumab treatment reduced impairment in work productivity and improved general health status in PsA over 2 years.

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13 heart centers earning designations in 90 days

Becker's Hospital Review - Cardiology

Stay up to date on the latest heart centers and programs receiving designations and accreditation in the last 90 days

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