HCPLive
FEBRUARY 29, 2024
Cancer patients with behavioral health disorders, such as substance abuse, eating disorders, and sleep disorders have a 7.76% increase in health care costs, a new study found.
DAIC
FEBRUARY 29, 2024
Five highly-anticipated late-breaking clinical trial sessions, an ACC/AHA guidelines update session and a host of featured clinical research sessions have been announced by program planners for the American College of Cardiology’s 73 rd Annual Scientific Session & Expo to be held April 6-8 in Atlanta, GA. Image courtesy: ACC christine.book Thu, 02/29/2024 - 11:22 February 29, 2024 — The American College of Cardiology ( ACC ) will soon be holding its ACC 73rd Annual Scientific Session & Expo , AC
Journal of the American Heart Association
FEBRUARY 29, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundPreoperative kidney dysfunction is a risk factor for right heart failure (RHF) after implantation of a left ventricular assist device (LVAD). However, characteristic kidney function trajectories before and after post‐LVAD RHF are uncertain, so we investigated this.Methods and ResultsWe identified individuals who received primary continuous‐flow LVAD implantation from July 1, 2014 to December 31, 2017 in the Interagency Registry
HCPLive
FEBRUARY 29, 2024
In honor of Rare Disease Day, this exploration of prurigo nodularis highlights the skin disease’s psychosocial impact on patients around the world living with the condition.
Journal of the American Heart Association
FEBRUARY 29, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundMyosin phosphatase targeting subunit 2 (MYPT2) is an important subunit of cardiac MLC (myosin light chain) phosphatase, which plays a crucial role in regulating the phosphorylation of MLC to phospho‐MLC (p‐MLC). A recent study demonstrated mineralocorticoid receptor‐related hypertension is associated with RhoA/Rho‐associated kinase/MYPT1 signaling upregulation in smooth muscle cells.
Becker's Hospital Review - Cardiology
FEBRUARY 29, 2024
Bakersfield (Calif.) Heart Hospital has been renamed by its new owner, Roseville, Calif.-based Adventist Health, Bakersfield.com reported Feb. 28.
HCPLive
FEBRUARY 29, 2024
This article serves as a landing page for our 3-part series spotlighting how a lack of diversity in clinical trials has had a deleterious downstream effect on real-world care for people of color in the US, with perspective from experts across more than half a dozen specialties.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HCPLive
FEBRUARY 29, 2024
In part 2 of our 3-part series on the impact of clinical trials lacking diversity, we are spotlighting responses to our second question, which addresses how the previously established lack of diversity in clinical trials has had a direct effect on the development and application of new therapies or devices in real-world settings.
American College of Cardiology
FEBRUARY 29, 2024
The following are key points to remember from a review article on the benefits of cardiac rehabilitation and current barriers to participation.
HCPLive
FEBRUARY 29, 2024
The latest episode of New Insight with Veeral Sheth, MD features a conversation with Brad Doerschuk, the CEO of InFocus Clinical Research, on the important role of contract research organizations in ophthalmology research.
American College of Cardiology
FEBRUARY 29, 2024
What is the safety and efficacy of aspirin withdrawal followed by P2Y12 inhibitor monotherapy with ticagrelor after a 3-month course of dual antiplatelet therapy (DAPT) among patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI)?
HCPLive
FEBRUARY 29, 2024
A progressive and significant increase in the frequency of strong opioid consumers was observed over a 12-year period, increasing from 5.8% to 12.8%.
Dr. S. Venkatesan MD
FEBRUARY 29, 2024
It is a 120-year challenge. Can anyone replace Rontgen’s X-ray discovered in 1895 for medical imaging? The Nobel winning Invention redefined the way we looked at our body and management of diseases for over a century. However, the fact remained it is an invasive and injuring investigation. What is the alternative for the X-radiation ? CT scan was a great invention, but it turned out to be a gigantic 360-degree clone of X-ray machine.
HCPLive
FEBRUARY 29, 2024
This analysis presented at AAAAI suggests that the experimental OMIT delivery of allergens via toothpaste may allow for a safer alternative to other immunotherapies.
MIBHS
FEBRUARY 29, 2024
There’s a good chance you’ve seen your doctor listen to your heartbeat through a stethoscope and look for a heart murmur. Heart murmurs occur when your heart makes an unusual sound. Characterized by a whooshing or swishing sound between heartbeats, a heart murmur is often completely normal and has no cause for concern. In fact, heart murmurs are quite common and often present in healthy individuals without heart problems.
HCPLive
FEBRUARY 29, 2024
Our February 2024 month in review highlights EoE pipeline news, new FMT guidelines, and research about endoscopic inflammation and disease activity in IBD.
American College of Cardiology
FEBRUARY 29, 2024
What are the real-world, long-term clinical outcomes after HeartMate 3 (HM3) left ventricular assist device (LVAD) implantation for heart failure (HF)?
HCPLive
FEBRUARY 29, 2024
People experiencing homelessness exhibit similar rates of morbidity compared with housed patients, but a longer adjusted length of hospital stay.
Frontiers in Cardiovascular Medicine
FEBRUARY 29, 2024
Background High pulse pressure (PP) and aortic root diameter (AoD) are hallmarks of arterial stiffness or vascular aging and they are considered as risk factors for age-related cardiovascular disease, including heart failure (HF). However, the relationship between PP and AoD in patients with heart failure (HF) is uncertain. This study aimed to evaluate the relationship between PP and AoD in the middle-aged and the elderly with HF.
HCPLive
FEBRUARY 29, 2024
Positive topline results show apraglutide outperformed placebo for relative change from baseline in actual weekly parenteral support volume at week 24 in adults with SBS-IF.
Frontiers in Cardiovascular Medicine
FEBRUARY 29, 2024
Researchers' interest in silicon as an element important for the functioning of the animal and human body began in the 1970s. Soluble compounds of silicon bioavailable from water and food seem to have important meaning for life processes occurring in the body. So far, researchers have focused on the significance of silicon for the development of bones and connective tissue, and its role in preventing neurodegenerative diseases and atherosclerosis.
HCPLive
FEBRUARY 29, 2024
At week 24, patients with moderate to severe PsA receiving risankizumab had a significantly higher ACR20 response rate when compared with placebo.
Frontiers in Cardiovascular Medicine
FEBRUARY 29, 2024
Objective The initial operation for type A aortic dissection has limitations, and there may be a need for reoperation in cases such as giant pseudoaneurysm formation and reduced blood supply to the distal vessels. In this study, we collected case data of patients who underwent cardiac major vascular surgery at our hospital to analyze the effectiveness of reoperation treatment options for type A aortic dissection and to summarize our treatment experience.
HCPLive
FEBRUARY 29, 2024
A new study found only 15% of people sleep the recommended 7 – 9 hours for ≥ 5 nights per week.
Journal of the American Heart Association
FEBRUARY 29, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundIdentifying novel molecular drivers of disease progression in heart failure (HF) is a high‐priority goal that may provide new therapeutic targets to improve patient outcomes. The authors investigated the relationship between plasma proteins and adverse outcomes in HF and their putative causal role using Mendelian randomization.Methods and ResultsThe authors measured 4776 plasma proteins among 1964 participants with HF with a re
HCPLive
FEBRUARY 29, 2024
In the final part of our 3-part series, our panel of experts discuss what their fields and its leaders could do to make sure this lack of diversity in trials does not continue. These responses are highlighted in the following video and transcribed below.
HeartRhythm
FEBRUARY 29, 2024
In the editorial commentary titled “Is more, “more” when itcomes to pacing in heart transplant patients?” by J. Rod Gimbel published in February 2024 (2024;21;161-162) in Heart Rhythm, the surname of the related article’s first author, Zain Gowani, is incorrectly referred to as Gowali. This has been corrected in the online journal. The author regrets this error.
HCPLive
FEBRUARY 29, 2024
In part 1 of our 3-part series on the impact of clinical trials lacking diversity, we are spotlighting responses to our first question, which sought to encapsulate the perspectives of our group of experts on how a historic lack of diversity in clinical trials has manifested itself in today’s care of patients from diverse backgrounds.
HeartRhythm
FEBRUARY 29, 2024
A rotational activation pattern (RAP) around the localized line of a conduction block often correlates with sites specific to the critical zones of ventricular tachycardia (VT). The wavefront direction during substrate mapping affects the manifestation of the RAP and line of block.
Journal of the American Heart Association
FEBRUARY 29, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundPrevious studies suggest an association between schizophrenia and stroke, but no studies have investigated stroke subtypes. We examined potential causal associations between schizophrenia and a range of atherosclerotic, embolic, and hemorrhagic stroke outcomes.Methods and ResultsTwo‐sample Mendelian randomization analyses were conducted.
HeartRhythm
FEBRUARY 29, 2024
Leadless pacemakers (LP) capable of VDD pacing allow for atrioventricular synchrony through mechanical sensing of atrial contraction. Unfortunately, mechanical sensing is less reliable and less predictable than electrical sensing.
Journal of the American Heart Association
FEBRUARY 29, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundImpaired arterial health is associated with a decline in cognitive function and psychopathology in adults. We hypothesized that these associations originate in early life. We examined the associations of blood pressure, common carotid artery intima media thickness, and carotid distensibility with behavior and cognitive outcomes during adolescence.Methods and ResultsThis study was embedded in the Dutch Generation R Study, a popu
Journal of Cardiovascular Electrophysiology
FEBRUARY 29, 2024
Abstract Introduction Various left atrial (LA) anatomical structures are correlated with postablative recurrence for atrial fibrillation (AF) patients. Comprehensively integrating anatomical structures, digitizing them, and implementing in-depth analysis, which may supply new insights, are needed. Thus, we aim to establish an interpretable model to identify AF patients' phenotypes according to LA anatomical morphology, using machine learning techniques.
Journal of the American Heart Association
FEBRUARY 29, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundThis study aimed to investigate the causal relationships between branched‐chain amino acids (BCAAs) and the risks of hypertension via meta‐analysis and Mendelian randomization analysis.Methods and ResultsA meta‐analysis of 32 845 subjects was conducted to evaluate the relationships between BCAAs and hypertension.
Journal of Cardiovascular Electrophysiology
FEBRUARY 29, 2024
Abstract Introduction Left bundle branch pacing (LBBP) is a physiological pacing modality. However, the long procedure and fluoroscopy time of LBBP is still a problem. This study aims to compare the clinical outcomes between transthoracic echocardiography (TTE)- and X-ray-guided LBBP. Methods This is a single-center, prospective, randomized controlled study.
Journal of the American Heart Association
FEBRUARY 29, 2024
Journal of the American Heart Association, Ahead of Print. BackgroundDelayed cerebral ischemia represents a significant contributor to death and disability following aneurysmal subarachnoid hemorrhage. Although preclinical models have shown promising results, clinical trials have consistently failed to replicate the success of therapeutic strategies.
Journal of Cardiovascular Electrophysiology
FEBRUARY 29, 2024
Intrinsic antitachycardia pacing (iATP) may be beneficial both as first-line and secondary therapies to terminate ventricular tachycardia (VT) effectively in comparison with conventional antitachycardia pacing (ATP). Our preliminary results highlight the unique algorithm of electrical-based, individual ATP and its possible benefit in terminating VT, which has future prospects for improving the prognosis of implantable cardioverter-defibrillator recipients.
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