HCPLive

JANUARY 13, 2024

Results confirmed the long-term efficacy of ustekinumab maintenance in patients with ulcerative colitis, demonstrating consistent rates of symptomatic remission and endoscopic improvement with no new safety signals.

104

104

Science Daily - Stroke

JANUARY 13, 2024

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.

Atherosclerosis 78

Atherosclerosis Research 78

Science Daily - Heart Disease

JANUARY 13, 2024

Uncertainty surrounding how truncated titin proteins (TTNtvs) cause dilated cardiomyopathy (DCM) and peripartum cardiomyopathy (PPCM) led to investigations that could better inform therapies for these conditions.

Cardiomyopathy 66

Cardiomyopathy 66

HeartRhythm

JANUARY 13, 2024

The increased risk of arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation has been a prominent safety pharmacology concern for the last 30 years. Between 1994 and 2004, 9 drugs were either removed from the market or had their use restricted because of an unacceptably high risk of lethal ventricular arrhythmias,1 caused by inadvertent block of human ether-a-go-go-related gene (hERG) potassium channels, which encode the rapid delayed-rectifier potassium current, an im

Sudden Cardiac Death 71

Sudden Cardiac Death Pharmacology Arrhythmia 71

Ken Grauer, MD

JANUARY 13, 2024

The ECG in Figure-1 was obtained from a middle-aged man with known hypertension — who presented to the ED ( E mergency D epartment ) for CP ( C hest P ain ) over the preceding 2-3 days. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? Should you activate the cath lab? If not — What next? Figure-1: The initial ECG in today's case — obtained from a middle-aged man with CP for the past 2-3 days.

Blog 148

Blog Ischemia AFIB Hypertension 148

HeartRhythm

JANUARY 13, 2024

Case reports suggest that quetiapine or haloperidol use is associated with severe QT prolongation (SQTP) and torsades de pointes.

Risk Factors 65

Risk Factors 65

Dr. Smith's ECG Blog

JANUARY 13, 2024

Written by Willy Frick A man in his 70s with a history of HFrEF and sick sinus syndrome s/p dual chamber pacemaker placement was admitted for overnight observation following outpatient placement of a mitral valve clip. The procedure note indicates uncomplicated clip placement. The next morning, the following ECG was obtained. What do you think? The tracing shows sinus rhythm with PVCs and non-specific ST&T wave abnormality.

Pacemaker 101

Pacemaker Bicuspid/Mitral Blood Pressure Bradycardia 101