Dr. Smith's ECG Blog
NOVEMBER 14, 2023
In the last post, we saw how important old ECGs are in assessing the current ECG in a patient without atypical presentation (in this previous case, the patient had no chest pain, and the apparent inferior OMI did not have reciprocal ST depression in lead aVL). Here is that last post: A 90-something with acute stroke. She has no chest symptoms. What is the diagnosis?
ECG Guru
NOVEMBER 14, 2023
Click to open: This original artwork was created by Dawn Altman. It is free for your use in a non-commercial setting. For commercial use, contact the artist at Dawn.ECGGuru@gmail.com. All rights reserved.
Open Heart
NOVEMBER 14, 2023
The main purpose of prognostic risk prediction models is to identify individuals who are at risk of disease, to enable early intervention. Current prognostic cardiovascular risk prediction models, such as the Systematic COronary Risk Evaluation (SCORE2) and the SCORE2-Older Persons (SCORE2-OP) models, which represent the clinically used gold standard in assessing patient risk for major cardiovascular events in the European Union (EU), generally overlook socioeconomic determinants, leading to dis
Society of Thoracic Surgeons - Early Career
NOVEMBER 14, 2023
Blog The Devil's Advocate pvaldez Tue, 11/14/2023 - 09:27 All Members Surgeon I am an annual contributor to the STS-PAC. Each year, however, as I consider whether to renew my contribution, I find myself in a state of internal debate around one central question. When I contribute to the PAC that is advocating for me, my colleagues and the future of my specialty, am I doing so to the ultimate benefit or detriment of our patients and society more broadly?
Open Heart
NOVEMBER 14, 2023
Background Out-of-hospital cardiac arrest (OHCA) has a dismal prognosis with overall survival around 10%. Previous studies have shown conflicting results regarding the prevalence and significance of comorbidities in OHCA, as well as the underlying causes. Previously, 80% of sudden cardiac arrest have been attributed to coronary artery disease. We studied comorbidities and discharge diagnoses in OHCA in all of Sweden.
NOVARAD
NOVEMBER 14, 2023
Medical images, from X-rays to MRIs, have transformed how healthcare professionals diagnose, treat, and understand many conditions. While offering unparalleled convenience, their digital nature also brings forth the challenges of secure storage and transmission. Medical image encryption isn't just a technical term; it's a critical shield ensuring that every pixel of these vital images remains confidential and uncompromised.
Dr. S. Venkatesan MD
NOVEMBER 14, 2023
Forget NEJM, Circulation, JACC, for some time. Hope & wish every one of us is aware of a journal called Blood , bringing stunning and dramatic discoveries week after week ,about the most crucial fluid that sustains our life. The journal Blood is published by the American Society of Hematology since 1949. Its impact factor is currently 20.8, celebrating its 75th year of existence.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Open Heart
NOVEMBER 14, 2023
Introduction Clopidogrel is a P2Y 12 inhibitor that has become a mainstay treatment following percutaneous intervention with drug-eluting stent placement to decrease restenosis and its potential complications, including sudden cardiac death and ischaemic strokes in patients with significant vascular disease. Areas covered As a prodrug, the metabolism and efficacy of clopidogrel are contingent on the presence of wild-type CYP450 (CYP2C19) alleles.
Journal of Cardiovascular Electrophysiology
NOVEMBER 14, 2023
During LBBAP, a strategy aiming to obtain LBB capture in every patient compared to a strategy accepting LVSP as a primary endpoint resulted in comparable implant parameters but higher rates of septal perforation. Patients with proven LBB capture showed a significantly narrow paced QRS but comparable LVEF changes to LVSP. Abstract Introduction Implant procedure features and clinical implications of left bundle branch pacing (LBBP) and left ventricular septal pacing (LVSP) have not been yet fully
Open Heart
NOVEMBER 14, 2023
Aims COVID-19 can cause severe illness and multiorgan dysfunction. Acute myocardial damage has been detected in a significant portion of patients with COVID-19; therefore, several studies have reported that electrocardiographic findings could be used to evaluate the severalty of COVID-19. However, performing standard ECG for each patient hospitalised with COVID-19 can increase the level of exposure to COVID-19 among medical staff.
Journal of Cardiovascular Electrophysiology
NOVEMBER 14, 2023
Abstract Introduction The circular catheter compatible with current cryoballoon system for atrial fibrillation (AF) ablation is exclusively sensed by impedance-based electro-anatomical mapping (EAM) system, limiting the accuracy of maps. We aim to investigate the feasibility and safety of a magnetic-based circular mapping catheter for AF ablation with cryoballoon.
JAMA Cardiology
NOVEMBER 14, 2023
A man in his 50s with recurrent palpitations, fatigue, and progressive exertion dyspnea had irregular narrow-QRS tachycardia in an incessant, repetitive fashion with heart rates up to 180 beats per minute and occasional short runs of wide-QRS tachycardia on Holter monitoring and 12-lead electrocardiogram. What would you do next?
European Journal of Heart Failure
NOVEMBER 14, 2023
The active ingredients in many traditional Chinese medicines are isoprene oligomers with a diterpenoid or triterpenoid structure, which exert cardiovascular effects by signalling through nutrient surplus and nutrient deprivation pathways. Qiliqiangxin (QLQX) is a commercial formulation of 11 different plant ingredients, whose active compounds include astragaloside IV, tanshione IIA, ginsenosides (Rb1, Rg1 and Re) and periplocymarin.
JAMA Cardiology
NOVEMBER 14, 2023
This post hoc analysis of the randomized Tafamidis in Transthyretin Cardiomyopathy Clinical Trial examines the effect of tafamidis vs placebo on 30-month changes in cardiac function in patients with transthyretin amyloid cardiomyopathy.
Circulation
NOVEMBER 14, 2023
Circulation, Ahead of Print. BACKGROUND:Cardiac metabolic dysfunction is a hallmark of heart failure (HF). Estrogen-related receptors ERRα and ERRγ are essential regulators of cardiac metabolism. Therefore, activation of ERR could be a potential therapeutic intervention for HF. However, in vivo studies demonstrating the potential usefulness of ERR agonist for HF treatment are lacking, because compounds with pharmacokinetics appropriate for in vivo use have not been available.METHODS:Using a stru
Science Daily - Heart Disease
NOVEMBER 14, 2023
Scientists have solve a 60-year-old mystery about one of the body's most vital organs: the heart.
Hypertension Journal
NOVEMBER 14, 2023
Hypertension, Volume 80, Issue 12 , Page 2544-2546, December 1, 2023.
Dr. Paddy Barrett
NOVEMBER 14, 2023
Let’s start with the simple fact that a lot of cancer diagnoses are simply down to ‘bad luck’ You can do everything right and still get cancer. This is a somewhat depressing fact, given its leading position as a cause of death. The other leading cause of death, cardiovascular disease, is mostly preventable. Cancer - Less so. Subscribe now But that does not mean you cannot tilt the odds in your favour.
Hypertension Journal
NOVEMBER 14, 2023
Hypertension, Volume 80, Issue 12 , Page 2556-2558, December 1, 2023.
Circulation
NOVEMBER 14, 2023
Circulation, Ahead of Print. BACKGROUND:Compared with men, women with hypertrophic cardiomyopathy (HCM) have a higher incidence of heart failure and worse outcomes. We investigated baseline clinical and echocardiographic characteristics and response to mavacamten among women compared with men in the EXPLORER-HCM study (Clinical Study to Evaluate Mavacamten [MYK-461] in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy).METHODS:A prespecified post hoc analysis of sex from the blinde
European Journal of Heart Failure
NOVEMBER 14, 2023
Sudden cardiac death in cardiomyoptahies: incidence, risk factors and prevention. AV, atrioventricular; CMR, cardiac magnetic resonance; CRT, cardiac resynchronization therapy; CV, cardiovascular; FLNC, filamin C; GDMT, guideline-directed medical therapy; HCM, hypertrophic cardiomyopathy; HFrEF, heart failure with reduced ejection fraction; ICD, implantable cardioverter-defibrillator; LGE, late gadolinium enhancement; LMNA, lamin A/C; LV, left ventricular; LVEF, left ventricular ejection fractio
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