Fri.Sep 13, 2024

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Direct-to-Consumer Drugs: Big Pharma's Digital Health Play

Med Page Today

(MedPage Today) -- More than a quarter of a century ago, the FDA eased regulations to make it easier for pharmaceutical companies to advertise directly to consumers. Today, it is nearly impossible to get through a family sitcom without hearing.

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Babies born to women consuming a high fat, sugary diet at greater risk of cardiovascular disease and diabetes in later life

Science Daily - Heart Disease

Babies born to pregnant women with obesity are more likely to develop heart problems and diabetes as adults due to fetal damage caused by the high-fat, high-energy diet of their mother.

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ECG Blog #447 — A "Prophetic" P Wave.

Ken Grauer, MD

I was sent the ECG shown in Figure-1 — being told only that providers on the case suspected AFib ( A trial Fib rillation ) with RBBB ( R ight B undle B ranch B lock ) aberrancy. QUESTIONS: Is the wide tachycardia that is seen best in the chest leads, too irregular to be VT ( V entricular T achycardia )? — How certain are YOU of your answer? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ). == PEARL # 1: Before reviewing my a

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Breakthrough is a game changer in heart valve technology

Science Daily - Heart Disease

When a patient needs a new heart valve, the current mechanical and tissue replacements each have strengths and weaknesses. Now, a team of researchers believe they have found a way to harness the strengths of both technologies in a way that could be life-changing -- and life-saving -- for many.

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Cannabis Cream Safely Reduces Itch in Patients with CKD-Associated Pruritus

HCPLive

A new study found cannabis-containing cream may be effective at alleviating itch in patients with chronic kidney disease (CKD)-associated pruritus with no adverse events.

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8-Hour Eating Window Improved Glycemic Control, Small Study Shows

Med Page Today

(MedPage Today) -- Eating within an 8-hour window improved glycemic variability in adults at risk for type 2 diabetes, an interim analysis of a randomized crossover study of 15 people showed. Compared with eating over 14+ hours per day, eating.

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Addison Gutierrez

Conquering CHD

The Warrior Heart Project Hi my name is Addison Gutierrez! On June 21, 2008 my mom went in for a routine ultrasound. She had low amniotic fluid which meant that she had to have an emergency C section. My dad was a surgery resident at the hospital so he was able to meet her there. I was born at 35 weeks with the lungs of a 28 week old and blue because of my lack of oxygen.

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Why Insulin Resistance Is The Biggest Silent Risk Factor For Heart Disease.

Dr. Paddy Barrett

Insulin resistance is a major risk factor for the leading causes of death, the leading one being cardiovascular disease. Everyone sits somewhere on the scale of insulin sensitivity from very insulin sensitive to very insulin resistant at the point of type 2 diabetes. Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers.

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Study Identifies Link Between Maternal Bread Consumption, Risk of Infant Allergies

HCPLive

In this analysis, an increased risk of allergy and eczema was associated with bread and thiamine intake increases during pregnancy.

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Increased testing for heart disease indicator needed worldwide, say experts

Medical Xpress - Cardiology

A review in The Lancet finds that 20% of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.

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C-Arm Radiation Exposure Prevention Tips for Safer Cardiovascular, IR and Hybrid Labs

Cassling

In healthcare, so much of safety and reference materials emphasize how to protect the patient, but there are far fewer resources dedicated toward helping protect you, the provider, over the course of time. While patients may be exposed to radiation only when they come in for an imaging exam or undergo a surgical procedure utilizing a C-arm, the providers who use these systems over the course of years are exposed again and again and again.

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Five facts about atrial fibrillation

Medical Xpress - Cardiology

Atrial fibrillation, or AFib, is a fast and irregular heart rhythm that, left untreated, can lead to blood clots, stroke and heart failure. It's the most common type of arrhythmia, a potentially serious condition in which the heart beats too quickly, too slowly or in an irregular pattern.

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FDA Approves Lebrikizumab Treatment of Eczema Among Patients Aged 12 and Older

HCPLive

Eli Lilly’s announcement of the lebrikizumab-lbkz approval for patients 12 years of age and older follows positive findings from the ADvocate 1, ADvocate 2, and ADhere studies.

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Scientists discover potential cause of an enigmatic vascular disease primarily impacting women

Medical Xpress - Cardiology

Mount Sinai researchers have identified a key driver of a blood vessel disorder known as fibromuscular dysplasia (FMD) which affects up to 5% of the adult population and can lead to high blood pressure, heart attack, or stroke.

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Hospitals with the lowest readmission rates for heart attack patients

Becker's Hospital Review - Cardiology

Discover the hospitals with the highest and lowest hospital return days for heart attack patients, according to CMS data collected from July 2019 to June 2022.

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FDA Approves Dupilumab for Adolescents with Chronic Rhinosinusitis with Nasal Polyps

HCPLive

This approval expands the drug’s age range and follows recent positive phase 3 findings on dupilumab treatment for patients aged 12 to 17 with CRSwNP.

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ACC CardiaCast: Pulse Check: PAD Interventional Treatment Options

American College of Cardiology

In this episode, Andrea Price, MS, AACC hosts Derek Pineda, NP, AACC, Bailey Estes, MSN, AGNP-C, and Pradeep Nair, MD, FACC for a discussion of interventional treatment options for PAD.

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Prescription Trends Between 2019 and 2022 Show the Rise of Telehealth

HCPLive

A recent study saw prescription fills for stimulants, and antidepressants increased from 2019 to 2022 but decreased for opioids.

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Researchers discover new target for treating heart failure: Protein kinase N

Science Daily - Heart Disease

As society ages, the number of patients with heart failure is rapidly increasing. The progression of the disease is caused by excessive growth of fibrotic tissue in the heart, known as fibrosis. A group has found that heart fibrosis is regulated by the enzyme protein kinase N (PKN). As there are no therapies targeting PKN, controlling this enzyme is a promising therapeutic target to develop new treatments against heart failure.

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Clinical significance of postoperative thrombocytosis after vats lobectomy for NSCLC

Journal of Cardiothoracic Surgery

Thrombocytosis is a clinical condition generally associated with poor prognosis in patients with cancer. Thrombocytosis may be present after lung cancer resection, but the clinical significance of thrombocytos.

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Intestinal fatty acid binding protein is associated with infarct size and cardiac function in acute heart failure following myocardial infarction

Open Heart

Background In acute heart failure (HF), reduced cardiac output, vasoconstriction and congestion may damage the intestinal mucosa and disrupt its barrier function. This could facilitate the leakage of bacterial products into circulation and contribute to inflammation and adverse cardiac remodelling. We aimed to investigate gut leakage markers and their associations with inflammation, infarct size and cardiac function.

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America’s Hypertension Awareness and Control Problem

CardiacWire

Nearly half of American adults have hypertension, and a new JAMA study reveals that the vast majority of them don’t have their blood pressure under control, while most don’t even know they have the disease. Estimates suggest that 120M U.S. adults have hypertension, while uncontrolled hypertension is associated with $131B-$198B in annual healthcare costs.

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Pregnancy complications and long-term risk of cardiovascular events in women with structural heart disease

Open Heart

Background To determine the frequency of pregnancy complications and their association with the risk of cardiovascular outcomes in women with structural heart disease (SHD). Methods This nationwide registry-based cohort study included women in Sweden with SHD (pulmonary arterial hypertension, congenital heart disease or acquired valvular heart disease) with singleton births registered in the national Medical Birth Register (MBR) between 1973 and 2014.

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Early Data for GLP-1 Pill; FAERS Tirzepatide Reports; AI Diabetes Voice Screening

Med Page Today

(MedPage Today) -- Studies presented at the European Association for the Study of Diabetes (EASD) annual meeting in Madrid included early data for oral amycretin, safety data for tirzepatide (Mounjaro, Zepbound), and voice screening for diabetes.

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Pretransplant cardiac stress testing and transplant wait time in kidney transplantation candidates

Open Heart

Objective Routine screening for cardiovascular disease before kidney transplantation remains controversial. This study aims to compare cardiac testing rates in patients with end-stage renal disease, referred and not referred for transplantation, and assess the impact of testing on transplant wait times. Methods This is a retrospective cohort study of 22 687 end-stage renal disease patients from 2011 to 2022, within an integrated health system.

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Managing Elevated Blood Pressure in the Hospital

NEJM Journal Watch - Cardiology

For the first time, a professional organization offers guidance for managing asymptomatic elevated BP in the hospital and at discharge.

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Positioning Medications in Crohn Disease, with Teddy Solomon, MSN, NP

HCPLive

Solomon explains how to navigate the growing Crohn disease treatment armamentarium and the importance of treatment positioning.

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Improving Guideline-Directed Medical Therapy for HF

American College of Cardiology

Does a collaborative nurse practitioner (NP) and pharmacist-led optimization program increase the use of guideline-directed medical therapy (GDMT) safely in patients with heart failure (HF)?

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Baseline Serum LDH Levels Predict Dupilumab Efficacy in Atopic Dermatitis

HCPLive

Multiple biomarkers and clinical background factors were linked to improved clinical outcomes after dupilumab therapy for AD.

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Study finds some male cross-country skiers at higher risk for bradycardia and pacemakers

Medical Xpress - Cardiology

Men who perform well in the cross-country ski race Vasaloppet are at increased risk of having abnormally low heart rates and pacemakers later in life. However, the researchers behind the study did not uncover any link to increased mortality, rather the opposite—the skiers lived longer than the general population.

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Lisa Richards, MSN, FNP-BC: Using Noninvasive Tests to Identify Fibrosis in MASH

HCPLive

Richards describes the utility of different NITs in primary and specialty care for risk-stratifying patients with MASH and fibrosis.

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ExtraCorporeal Life Support for acute myocardial infarction complicated by cardiogenic shock

American College of Cardiology

The goal of the ECLS-SHOCK trial was to evaluate extracorporeal life support (ECLS) compared with control among patients with acute myocardial infarction (MI) and cardiogenic shock.

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Nanoscope Reports Positive End-of-Phase 2 Meeting for MCO-010 Gene Therapy

HCPLive

Nanoscope Therapeutics announced the meeting with the FDA supported the advancement of MCO-010 into Phase 3 for Stargardt disease.

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Calcium Burden, Vascular Inflammation, and Plaque Vulnerability

American College of Cardiology

Is calcified plaque burden (CPB) associated with vascular inflammation and plaque vulnerability?

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Many US adults with uncontrolled hypertension are unaware of hypertension status

Medical Xpress - Cardiology

More than half of adults with uncontrolled hypertension are unaware that they have hypertension, according to a study published online Sept. 11 in JAMA Network Open.

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Follicle-stimulating hormone promotes atrial fibrosis in menopausal women with atrial fibrillation

HeartRhythm

Postmenopausal women with atrial fibrillation (AF) exhibit a higher level of atrial fibrosis and a higher recurrence rate after ablation compared to men. However, the underlying mechanism remains unclear.

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Higher Risk of Interstitial Lung Disease in Patients With RA, PsA Initiating bDMARDs

HCPLive

There were no differences in risk between patients with RA or PsA using or not using methotrexate.

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