Golgi protein 73 promotes LPS-induced cardiac dysfunction via mediating myocardial apoptosis and autophagy
Journal of Cardiovascular Pharmacology
SEPTEMBER 25, 2023
Sepsis-induced cardiac dysfunction represents a major cause of high mortality in intensive care units with limited therapeutic options. Golgi protein 73 (GP73) has been implicated in various diseases. However, the role of GP73 in LPS-induced cardiac dysfunction is unclear. Here, we established sepsis-induced cardiac dysfunction model by LPS administration in wild type (WT) and GP73 knockout (GP73-/-) mice.
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