Cardiometabolic Health Congress

JANUARY 16, 2025

Atherosclerosis (ASVD) remains a leading driver of cardiovascular disease (CVD), a global health challenge that claims millions of lives each year. But what if prevention could rewrite the narrative? Explore actionable, evidence-based strategies to combat traditional and emerging risk factors, with a focus on precision approaches and primordial prevention.

Atherosclerosis 59

Atherosclerosis Risk Factors Coronary Artery Disease Cardiovascular Disease 59

Frontiers in Cardiovascular Medicine

JANUARY 16, 2025

Calcific aortic valve disease (CAVD) is a common cardiovascular condition in the elderly population. The aortic valve, influenced by factors such as endothelial dysfunction, inflammation, oxidative stress, lipid metabolism disorders, calcium deposition, and extracellular matrix remodeling, undergoes fibrosis and calcification, ultimately leading to stenosis.

Aortic valve 52

Aortic valve Aortic Stenosis Research 52

HCPLive

JANUARY 16, 2025

Current asthma diagnosis requires specialized breathing tests that can be challenging for young children.

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Frontiers in Cardiovascular Medicine

JANUARY 16, 2025

BackgroundPeripheral arterial disease (PAD) is a prevalent cardiovascular condition that affects up to 200 million people globally, and has significant implications for morbidity and mortality. Recent studies have identified the red cell distribution width-to-albumin ratio (RDW/ALB) as a potential systemic inflammatory marker that is correlated with several cardiovascular and inflammatory diseases including PAD.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Research 52

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

HCPLive

JANUARY 16, 2025

Heat therapy often worsened symptoms in a randomized controlled trial.

Research 111

Research 111

Med Page Today

JANUARY 16, 2025

(MedPage Today) -- After patients with obesity discuss bariatric surgery with a clinician, racial disparities appeared to affect who moves forward with the procedure, according to 20 years of retrospective data. Among 122,487 patients with class.

Obesity 104

Obesity 104

Journal of the American Heart Association

JANUARY 16, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundThe coexistence of transthyretin cardiac amyloidosis (ATTRCA) and aortic stenosis (AS) is increasingly recognized, but the clinical consequences are unclear. We aimed to characterize clinical outcomes in AS plus ATTRCA compared with only AS or ATTRCA.Methods and ResultsIn a retrospective cohort study, patients with AS only, ATTRCA only, or AS plus ATTRCA were identified using allpayer claims data (20152021).

Aortic 73

Aortic Aortic valve Stenosis Outcomes 73

HCPLive

JANUARY 16, 2025

Boehringer Ingelheims phase 3 trial of iclepertin for cognitive impairment in schizophrenia failed to meet primary and secondary endpoints, showing no significant effects.

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Med Page Today

JANUARY 16, 2025

(MedPage Today) -- People with transthyretin cardiac amyloidosis (ATTR-CA) on top of aortic stenosis (AS) fared particularly poorly in a large cohort study, which researchers said calls for awareness and timely treatment. Compared with AS alone.

Stenosis 59

Stenosis Aortic Outcomes Research 59

HCPLive

JANUARY 16, 2025

A study shows the causal link between apoA-I and chronic obstructive pulmonary disease, showing lipid metabolism's role in the pathogenesis of COPD.

Pulmonary 104

Pulmonary 104

Med Page Today

JANUARY 16, 2025

(MedPage Today) -- Note that some links may require registration or subscription. Pope Francis injured his right arm after a fall, requiring a sling, just weeks after bruising his chin from another fall. (AP) Air quality has improved in Los Angeles.

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HCPLive

JANUARY 16, 2025

Shadi Kourosh, MD, MPH, joins The Medical Sisterhood to discuss advocacy, mentorship, and the empowerment of women in medicine.

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Journal of Cardiothoracic Surgery

JANUARY 16, 2025

Gout is a metabolic disease caused by decreased blood uric acid excretion and purine metabolism disorders. Long-term and persistent metabolic dysfunction gradually affects other organ functions and is the main.

Myocardial Infarction 52

Myocardial Infarction Heart Failure Research 52

HCPLive

JANUARY 16, 2025

In this episode, hosts explore ADA's evolving guidelines championing broader access to CGM and AID systems for personalized diabetes care.

Diabetes 64

Diabetes Technology 64

Journal of Cardiothoracic Surgery

JANUARY 16, 2025

Atherosclerosis (AS) is increasingly recognized as a chronic inflammatory disease that significantly compromises vascular health and acts as a major contributor to cardiovascular diseases. Advancements in lipi.

Atherosclerosis 52

Atherosclerosis Biomarkers Cardiovascular Disease Research 52

HCPLive

JANUARY 16, 2025

These data highlight current applications of AI and machine learning in aesthetic medicine, looking specifically at studies graded as Level I or II.

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Becker's Hospital Review - Cardiology

JANUARY 16, 2025

Utilizing telehealth and remote monitoring for at-home cardiac rehabilitation showed little to no benefit among older adults, according to a study published Jan. 8 in JAMA Network Open.

Cardiac Rehabilitation 52

Cardiac Rehabilitation 52

HCPLive

JANUARY 16, 2025

UCB announced that a new dosing option for bimekizumab-bkzx is now available through prescription for conditions such as psoriasis, hidradenitis suppurativa, and psoriatic arthritis.

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Becker's Hospital Review - Cardiology

JANUARY 16, 2025

Oklahoma City-based Oklahoma Children's Hospital OU Health used an adolescent patient's own tissue to reconstruct a leaky heart valve, CBS affiliate KWTV reported Jan. 15.

Heart Valves 52

Heart Valves Hospital 52

HCPLive

JANUARY 16, 2025

In a validated microsimulation model, annual CRC screening with FIT was the most cost-effective strategy among patients with low adherence.

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HeartRhythm

JANUARY 16, 2025

A 64-year-old male with recurrent ventricular tachycardia (VT) was referred for repeat ablation. He had undergone three prior VT ablation procedures elsewhere. His medical history included prior myocardial infarction and cardiac magnetic resonance imaging demonstrated basal inferior and anteroseptal subendocardial scar with overall preserved left ventricular function.

Tachycardia 45

Tachycardia Myocardial Infarction Ablation 45

HCPLive

JANUARY 16, 2025

Axatilimab in 9 mg and 22 mg vial sizes are expected to launch in early February for the treatment of chronic graft-versus-host disease.

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Journal of the American Heart Association

JANUARY 16, 2025

Journal of the American Heart Association, Ahead of Print.

Stenosis 45

Stenosis Aortic 45

Hypertension Journal

JANUARY 16, 2025

Hypertension, Ahead of Print. BACKGROUND:Adrenomedullin 2 (AM2) plays critical roles in regulating blood pressure and fluid balance. However, the specific involvement of AM2 in cardiac hypertrophy has not been comprehensively elucidated, warranting further investigation into its molecular mechanisms and therapeutic implications.METHODS:Cardiac hypertrophy was induced in adult mice lacking AM2 (AM2/) using transverse aortic constriction surgery.

Aortic 45

Aortic Blood Pressure Heart Failure Hypertension 45

Journal of the American Heart Association

JANUARY 16, 2025

Journal of the American Heart Association, Ahead of Print.

Diabetes 45

Diabetes 45

Circulation: Cardiovascular Quality & Outcomes

JANUARY 16, 2025

Circulation: Cardiovascular Quality and Outcomes, Volume 18, Issue 3 , Page e011544, March 1, 2025.

Innovation 40

Innovation Defibrillator Circulation Outcomes 40

Journal of the American Heart Association

JANUARY 16, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundProstaglandin E2(PGE2) in the rostral ventrolateral medulla (RVLM) has been recognized as a pivotal pressor substance in hypertension, yet understanding of its effects and origins in the RVLM remains largely elusive. This study aimed to elucidate the pivotal enzymes and molecular mechanisms underlying PGE2synthesis induced by central Ang II (angiotensin II) and its implications in the heightened oxidative stress and sympathetic

Hypertension 45

Hypertension 45

Circulation: Heart Failure

JANUARY 16, 2025

Circulation: Heart Failure, Ahead of Print. BACKGROUND:Right ventricular dysfunction (RVD) is common in patients with heart failure with reduced ejection fraction, and it is associated with poor prognosis. However, no biomarker reflecting RVD is available for routine clinical use.METHODS:Proteomic analysis of myocardium from the left ventricle and right ventricle (RV) of patients with heart failure with reduced ejection fraction with (n=10) and without RVD (n=10) who underwent heart transplantat

Biomarkers 40

Biomarkers Heart Failure Heart Transplant Transplant 40

Journal of the American Heart Association

JANUARY 16, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundValvular heart disease (VHD) is a major focus of cardiovascular medicine, but limited data are available for racial and ethnic minorities. The aim was to assess the burden and clinical correlates of VHD in a highly diverse area of the United States.Methods and ResultsIndividuals with echocardiographic diagnosis of native VHD between January 2010 and December 2019 at a quaternary care health system of the Bronx (New York, USA) w

Heart Disease 45

Heart Disease Tricuspid Bicuspid/Mitral Echocardiogram 45

HeartRhythm

JANUARY 16, 2025

Focal pulsed-field ablation (F-PFA) integrated in electroanatomical mapping (EAM) systems allows tailored lesion sets in patients with atrial fibrillation (AF).

Atrial Fibrillation 40

Atrial Fibrillation Ablation 40

Journal of the American Heart Association

JANUARY 16, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundThe purpose of this study was to investigate whether circulating pyruvate kinase M2 (PKM2) levels are elevated in the peripheral blood and to assess their association with diagnosis and prognosis in patients with heart failure (HF).Methods and ResultsWe conducted a prospective investigation involving 222 patients with HF and 103 control subjects, measuring PKM2 concentrations using ELISA.

Cardiac Function 45

Cardiac Function Heart Failure Biomarkers Preserved Ejection Fraction 45

Journal of Cardiothoracic Surgery

JANUARY 16, 2025

The lacking proper regulation of International Normalized Ratio (INR) as the main problem in patients with mechanical valve replacement surgery poses the risk of thrombosis and embolism on the one hand and the.

Heart Valves 40

Heart Valves Thrombosis Embolism Research 40

Journal of the American Heart Association

JANUARY 16, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundPatients with atrial fibrillation (AF) who suffered a previous stroke are at increased risk of recurrent thromboembolic events and other major outcomes. The impact of the number of stroke episodes on the natural history of patients with AF is still unclear.Methods and ResultsUsing data from the international, multicenter, and prospective GLORIAAF (Global Registry on LongTerm Oral Antithrombotic Treatment in Patients With Atrial

Atrial Fibrillation 45

Atrial Fibrillation Stroke Strokes Outcomes 45

HeartRhythm

JANUARY 16, 2025

Vasovagal syncope (VVS) is the most common type of syncope affecting up to 42% of woman and 32% of men by the age of 601. While several drugs are indicated in the treatment of VVS, to our knowledge, there is no current treatment of an impending syncopal attack.

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Journal of the American Heart Association

JANUARY 16, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundPolyamines have been suggested to play pivotal roles in ischemic stroke and neurodegenerative disorders, but the associations of plasma polyamines with poststroke cognitive impairment (PSCI) remain unclear. We aimed to prospectively investigate the associations of plasma putrescine, spermidine, and spermine with PSCI among patients with ischemic stroke in a multicenter cohort study.Methods and ResultsWe measured plasma polyamin

Stroke 45

Stroke Strokes Risk Factors 45

Journal of Cardiovascular Electrophysiology

JANUARY 16, 2025

ABSTRACT Background Electrographic flow (EGF) mapping allows for the visualization of global atrial wavefront propagations. One mechanism of initiation and maintenance of atrial fibrillation (AF) is stimulation from EGF-identified focal sources that serve as driver sites of fibrillatory conduction. Electrographic flow consistency (EGFC) further quantifies the concordance of observed wavefront patterns, indicating that a healthier substrate shows more organized wavefront propagation and higher EG

Atrial Fibrillation 40

Atrial Fibrillation Ablation Pulmonary Article 40