Becker's Hospital Review - Cardiology
SEPTEMBER 3, 2024
Chicago-based Northwestern Memorial Hospital and VA Boston Healthcare System-Jamaica Plain (Mass.) have the lowest death rate for heart failure patients in the country, according to CMS data.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 3, 2024
Liraglutide, a glucagon-like peptide-1 (GLP-1) analog, is approved for obesity treatment, but the specific neuronal sites that contribute to its therapeutic effects remain elusive. Here, we show that GLP-1 receptor–positive (GLP-1R–positive) neurons in the lateral septum (LSGLP-1R) play a critical role in mediating the anorectic and weight-loss effects of liraglutide.
HCPLive
SEPTEMBER 3, 2024
The decision to revoke the conditional marketing authorization is based on a June 2024 CHMP recommendation from the EMA suggesting the benefits of Ocaliva do not outweigh its risks.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
A new study has found that regular mobile phone use was positively associated with incident cardiovascular disease risk, especially in current smokers and individuals with diabetes. In addition, this association was partly attributed to poor sleep, psychological distress, and neuroticism.
Med Page Today
SEPTEMBER 3, 2024
(MedPage Today) -- Two trajectories of brain aging were identified in a cellular analysis of post-mortem brain tissue: one leading to Alzheimer's disease, the other to an alternative brain aging pathway. The study involved participants in the.
Science Daily - Heart Disease
SEPTEMBER 3, 2024
Heart failure during pregnancy is a dangerous and often under-detected condition because common symptoms -- shortness of breath, extreme fatigue and trouble breathing while lying down -- are easily mistaken for typical pregnancy discomforts. A new study showed an artificial intelligence (AI)-enabled digital stethoscope helped doctors identify twice as many cases of heart failure compared to a control group that received usual obstetric care and screening.
Med Page Today
SEPTEMBER 3, 2024
(MedPage Today) -- I'm a retired doctor who walks about 8 miles on some rural roads each morning. People sometimes stop to ask me medical questions. Some call me, "The Street Doctor." Last week, a 72-year-old man stopped to tell me about his heart.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Olive oil has long been touted for its ability to lower heart disease risk. So University of Florida researchers set out to dig deeper to learn how much olive oil is beneficial.
Med Page Today
SEPTEMBER 3, 2024
(MedPage Today) -- LONDON -- Routine coronary intervention was safe and somewhat beneficial for older people with non-ST-segment elevation myocardial infarction (NSTEMI) in the SENIOR-RITA trial, unique for being designed to be broadly representative.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
A new, rapid blood test that spots whether people are having a heart attack could improve the treatment of people presenting with chest pain at emergency departments, according to late-breaking research presented in a Hot Line Session Sept. 2 at this year's ESC Congress 2024.
Cassling
SEPTEMBER 3, 2024
The ASRT Foundation, the philanthropic arm of the American Society of Radiologic Technologists, has announced the recipients of this year’s Bob Cassling Memorial Scholarship, which provides $4,000 to rural healthcare professionals pursuing higher education in the field of medical imaging and radiation therapy.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.
Med Page Today
SEPTEMBER 3, 2024
(MedPage Today) -- Two new studies published in JAMA Internal Medicine do not support a previously reported association between GLP-1 receptor agonists and a signal for suicidal ideation. In an analysis of nearly 300,000 new users of a GLP-1 agonist.
HCPLive
SEPTEMBER 3, 2024
This August 2024 month in review highlights updates to the ophthalmic pipeline, metformin for geographic atrophy, and decreasing rates of postoperative endophthalmitis in the US.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Women, people of Black ethnicity and those from low income households in England are less likely to be offered heart surgery than men, white people, and those who are affluent, finds research published online in the journal Heart.
HCPLive
SEPTEMBER 3, 2024
A study suggests transient elastography and fibrosis-4 index may be effective in predicting hepatocellular carcinoma risk in hepatitis C patients.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Severe, lasting hot flushes during menopause are associated with atherosclerosis in the coronary artery, new research from Karolinska Institutet and Linköping University and published in the Journal of the American Heart Association reveals.
HCPLive
SEPTEMBER 3, 2024
This month in review highlights the top sleep stories in August, from sleep health in patients undergoing dialysis to the benefits of catching up on sleep.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 3, 2024
Sarcoidosis is a multiorgan granulomatous disease that lacks diagnostic biomarkers and targeted treatments. Using blood and skin from patients with sarcoid and non-sarcoid skin granulomas, we discovered that skin granulomas from different diseases exhibit unique immune cell recruitment and molecular signatures. Sarcoid skin granulomas were specifically enriched for type 1 innate lymphoid cells (ILC1s) and B cells and exhibited molecular programs associated with formation of mature tertiary lymph
HCPLive
SEPTEMBER 3, 2024
In this review of August 2024, the editorial team highlighted major stories from the previous month related to FDA approvals and medications for atopic dermatitis and psoriasis.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 3, 2024
Adeno-associated virus (AAV) is a promising in vivo gene delivery platform showing advantages in delivering therapeutic molecules to difficult or undruggable cells. However, natural AAV serotypes have insufficient transduction specificity and efficiency in kidney cells. Here, we developed an evolution-directed selection protocol for renal glomeruli and identified what we believe to be a new vector termed AAV2-GEC that specifically and efficiently targets the glomerular endothelial cells (GEC) af
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Undergoing percutaneous coronary intervention (PCI) for narrowed arteries with a novel bioadaptor is at least as effective as a contemporary drug-eluting stent (DES) with regard to target lesion and target vessel failure outcomes at one year in a large, broad clinical population. This late breaking research was presented in a Hot Line session Sept. 2 at this year's ESC Congress 2024.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 3, 2024
Obesity is a known driver of endometrial cancer. In this issue of the JCI, Gómez-Banoy and colleagues investigated a cohort of patients with advanced endometrial cancer treated with immune checkpoint inhibitors targeting the interaction between programmed cell death receptor-1 (PD-1) and its ligand (PD-L1). Notably, a BMI in the overweight or obese range was paradoxically associated with improved progression-free and overall survival.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Mitral transcatheter edge-to-edge repair (M-TEER) reduced cardiovascular death and heart failure (HF)-related hospitalizations with improved health status in patients with HF and moderate to severe functional mitral regurgitation (FMR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024. The paper is published in the New England Journal of Medicine.
Dr. S. Venkatesan MD
SEPTEMBER 3, 2024
Echocardiography, the ultrasonic vision, with which we are able to directly visualize the heart is a monumental discovery ,gifted to us by Edler & Hertz in the 1950s. These high frequency sound interacts with myocytes in a variety of ways like penetration ,reflection, ab & adsorption, back scattering etc. It has further evolved , at the tissue level diagnostic like 3D speckle ,and strain etc.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
A team from the University's School of Medicine, working with Red Star AI, were able to identify alternative treatment plans for patients who may currently be on outdated or less effective treatment plans.
Med Page Today
SEPTEMBER 3, 2024
(MedPage Today) -- LONDON -- It was best that people interrupt their oral anticoagulation (OAC) therapy around the time they get transcatheter aortic valve replacement (TAVR, also TAVI), the POPular PAUSE TAVI trial found. The question of periprocedural.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 3, 2024
Tumor reliance on glycolysis is a hallmark of cancer. Immunotherapy is more effective in controlling glycolysis-low tumors lacking lactate dehydrogenase (LDH) due to reduced tumor lactate efflux and enhanced glucose availability within the tumor microenvironment (TME). LDH inhibitors (LDHi) reduce glucose uptake and tumor growth in preclinical models, but their impact on tumor-infiltrating T cells is not fully elucidated.
Med Page Today
SEPTEMBER 3, 2024
(MedPage Today) -- The RHEIA trial, which found transcatheter aortic valve replacement (TAVR) superior to surgery for women, was among the highlights of the European Society of Cardiology (ESC) congress. Also at ESC was OCCUPI, which showed that.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 3, 2024
The progression of kidney disease varies among individuals, but a general methodology to quantify disease timelines is lacking. Particularly challenging is the task of determining the potential for recovery from acute kidney injury following various insults. Here, we report that quantitation of post-transcriptional adenosine-to-inosine (A-to-I) RNA editing offers a distinct genome-wide signature, enabling the delineation of disease trajectories in the kidney.
Med Page Today
SEPTEMBER 3, 2024
(MedPage Today) -- Patients with the genetic recessive disorder persistent chylomicronemia who received the investigational drug plozasiran had significantly lower triglyceride levels and a reduced risk of acute pancreatitis compared with a placebo.
CardiacWire
SEPTEMBER 3, 2024
Alylam’s vutrisiran dominated early ESC 2024 headlines and conversations, after full results from the Phase 3 HELIOS-B trial highlighted its significant impact on transthyretin amyloidosis with cardiomyopathy (ATTR-CM). ATTR-CM is a rare, progressive heart disease caused by the buildup of amyloid protein in the heart, and is currently only treated with Pfizer’s ATTR-CM “stabilizer” tafamidis.
Med Page Today
SEPTEMBER 3, 2024
(MedPage Today) -- LONDON -- A set of new European guidelines streamlined recommendations for atrial fibrillation (Afib), chronic coronary disease, peripheral artery disease (PAD) and aortic disease, and hypertension, with an emphasis on shared.
HCPLive
SEPTEMBER 3, 2024
Investigators noted that a formal independent validation cohort needs to be developed in order to realize the full potential of the human model.
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
There was no difference in efficacy between transcatheter edge-to-edge repair (TEER) and surgery in patients with secondary mitral regurgitation (MR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024. The findings are published in the New England Journal of Medicine.
HCPLive
SEPTEMBER 3, 2024
Ahmad Masri, MD, MS, discusses an integrated safety analysis of aficamten using data from 3 clinical trials.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 3, 2024
Sarcoidosis is an inflammatory disease characterized by immune cell–rich granulomas that form in multiple organs. In this issue of the JCI, Sati and colleagues used scRNA-seq and spatial transcriptomics of skin samples from patients with sarcoidosis and non-sarcoidosis granulomatous disease to identify upregulation of a stromal-immune CXCL12/CXCR4 axis and accumulation of type 1 innate lymphoid cells (ILC1s) in sarcoidosis.
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