Fri.Sep 06, 2024

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Reagan Udall Foundation for FDA Facilitates Discussion on Urgent Needs in PTSD Therapy

HCPLive

The Reagan Udall Foundation hosted a meeting on PTSD treatment needs, with experts and stakeholders highlighting gaps and potential therapies, including MDMA-assisted therapy.

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ECG Blog #446 — What Kind of SVT?

Ken Grauer, MD

You are shown the ECG in Figure-1 — told only that the patient had a “continuous" tachycardia. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? What is the differential diagnosis? — Treatment? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ). MY Thoughts on the ECG in Figure-1: The rhythm in Figure-1 — is a regular SVT ( S upra V entricular T achycardia ) at a rate just under 150/minute , without clear sign of sinus

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Physiology Friday #234: Is It Time to Retire the Idea of the "Healthy Sedentary" Person?

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Thanks to the premium sponsor of this newsletter: FSTFUEL electrolyte supplement. FSTFUEL combines electrolytes with amino acids to help your body maintain hydration and optimal functioning during exercise or intermittent fasting, so you don't have to choose between fasting and fitness. It’s a zero-sugar electrolyte drink that tastes awesome.

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Study Unlocks Key Bacteria That Explains Why Only Some with IBD Respond to Thiamine

HCPLive

A new study discovers patients with IBD who respond well to high-dose thiamine treatment have an abundance of faecalibacterium prausnitzii.

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Lessons learnt from HF coding in primary care. What might best practice look like?

The British Journal of Cardiology

Heart failure (HF) is a prevalent and complex condition that demands precise and efficient management. This paper delves into a critical, yet often under-recognised, challenge in HF care – the accurate coding of patients on HF registers. We explore how discrepancies in coding, including missing patients and incorrect HF type classifications, can significantly impact patient management.

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You Don't Want Money. You Want Time.

Dr. Paddy Barrett

If you spend long enough thinking about health, you will come to a singular realisation: Regardless of how long you live or how good your physical or cognitive capabilities are, how you spend your time will have the biggest impact on the quality of your life. This is the domain of soul span. Soul span is about how you optimise for meaning and purpose in your life.

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Jonathan Barratt, PhD, FRCP: Sparsentan Full FDA Approval, Future IgAN Developments

HCPLive

Barratt reflects on recent therapeutic developments in IgAN, the most recent being the full FDA approval of sparsentan (Filspari), and the importance of preventing kidney failure.

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More Trending

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US Veterans Have Higher Prevalence of Skin Cancer, Psoriasis Versus Non-Veterans

HCPLive

These findings further endorse the need for health care quality improvements for veterans, given the rates of melanoma, skin cancer, and psoriasis.

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Correspondence: Prevention of stroke

The British Journal of Cardiology

Dear Sirs, In the recent article ‘Drug therapies for stroke prevention’, under the heading entitled ‘Control of blood pressure’, the authors specified that “A systolic blood pressure (SBP) target of 120–129 mmHg should be routinely aimed for in those <65 years old….”. 1 This ‘goal’ SBP does not take recognition of the fact that the goal SBP that optimally mitigates the risk of incident atrial fibrillation (AF) and, hence, cardioembolic stroke, is a SBP <120 mmHg.

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FIB-4, Forns Index May Aid Noninvasive Fibrosis Staging in Chronic HCV

HCPLive

Findings support the use of FIB-4’s low cut-off for ruling out severe fibrosis and cirrhosis as well as the use of Forns index’s high cut-off for significant fibrosis in chronic HCV.

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British Cardiovascular Society annual conference, 2024: back to the patient

The British Journal of Cardiology

The British Cardiovascular Society (BCS) annual conference returned to the Manchester Central Convention Complex on the 3–5 June 2024. This year’s focus was our most important stakeholder, the patient – highlighting how research, pharmaceutical and technological advancements are improving patient outcomes, and the importance of value-based care.

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Cardiology Month in Review: August 2024

HCPLive

The August 2024 cardiology month in review highlights critical data from the European Society of Cardiology Congress 24 and the latest updates on finerenone.

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Integrated working in cardiovascular care

The British Journal of Cardiology

There is little doubt that demand on the National Health Service (NHS) has exceeded supply. Given the rhetoric of no more money, no new workforce, and no new estates, it is incumbent on us all to make better and more efficient use of the limited resource we do have, improve how we work together as one integrated health, community and social care ecosystem, and increase the value of every action we take.

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Methotrexate/Hydroxychloroquine Combo Beats MTX Alone in Rheumatoid Arthritis Treatment

HCPLive

The MTX + HCQ group had a higher, but not statistically significant, incidence rate of TEAEs than the monotherapy group.

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Navigating the research landscape in cardiology. Part 4: beyond the finish line

The British Journal of Cardiology

In this four-part editorial series, we have looked at the significance of research within cardiology training in the UK. The first three instalments explored the impact of research on a career in cardiology, identified the diverse research avenues, and provided guidance on navigating the application process. In the final part of this series, our focus shifts to post-higher degree opportunities within the field, and discuss the skills developed in research that can be applied to clinical practice

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Study Compares Safety of JAK Inhibitors Between Adolescent, Adult Patients

HCPLive

In this analysis, the differences in adverse events resulting from JAKi among adults and children were evaluated.

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Colchicine in Patients with Coronary Disease Undergoing Coronary Artery Bypass Surgery – A Meta-Analysis of Randomized Controlled Trials

The American Journal of Cardiology

Publication date: Available online 5 September 2024 Source: The American Journal of Cardiology Author(s): Hristo Kirov, Tulio Caldonazo, Angelique Runkel, Darko Medin, Johannes Fischer, Luis Roberto Dallan, Murat Mukharyamov, Omar A. Mejia, Fabio B.

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Upcoming Research in PsA, AxSpa, with Philip Mease, MD

HCPLive

Mease went over research initiatives including the ARGO, AXIS, and STAR studies.

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Association Between Lipoprotein(a) and Obstructive Coronary Artery Disease and High-Risk Plaque: Insights From the PROMISE Trial

The American Journal of Cardiology

Publication date: Available online 6 September 2024 Source: The American Journal of Cardiology Author(s): Thomas O'Toole, Nishant P. Shah, Stephanie Nicole Giamberardino, Lydia Coulter Kwee, Deepak Voora, Robert W. McGarrah, Maros Ferencik, Michael T. Lu, William E. Kraus, Borek Foldyna, Pamela S. Douglas, Svati H. Shah, Neha J.

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Correction to: Central Hemodynamics in Black Women: Examining the Role of Superwoman Schema Endorsement [Central Hemodynamics in African American Women: Examining the Role of Superwoman Schema Endorsement]

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print.

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Implications of diuretic use in contextualizing clinical trial results in patients with heart failure with preserved ejection fraction

The American Journal of Cardiology

Publication date: Available online 5 September 2024 Source: The American Journal of Cardiology Author(s): Muhammad Shahzeb Khan, Rohan Kumar Ochani, Javed Butler

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New Research from the ESC Congress 2024

NEJM Journal Watch - Cardiology

NEJM Journal Watch coverage of the meeting