Tue.Aug 13, 2024

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Say 'aah' and get a diagnosis on the spot: is this the future of health?

Science Daily - Stroke

A computer algorithm has achieved a 98% accuracy in predicting different diseases by analyzing the color of the human tongue. The proposed imaging system can diagnose diabetes, stroke, anemia, asthma, liver and gallbladder conditions, COVID-19, and a range of vascular and gastrointestinal issues, according to new research.

COVID-19 127
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Well-Being Declines Before Mild Cognitive Impairment

Med Page Today

(MedPage Today) -- Psychological well-being waned in the years before mild cognitive impairment, a study of older adults in the Chicago area showed. Among 910 cognitively normal older adults who were followed for up to 14 years, those who developed.

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Previewing the Family Heart Global Summit, with Laurence Sperling, MD

HCPLive

Laurence Sperling, MD, provides an overview of the Family Heart Global Summit, including previewing the meeting and discussing where interested attendees can learn more.

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Interactions between the gut microbiome, associated metabolites and the manifestation and progression of heart failure with preserved ejection fraction in ZSF1 rats

Cardiovascular Diabetology

Heart failure with preserved ejection fraction (HFpEF) is associated with systemic inflammation, obesity, metabolic syndrome, and gut microbiome changes. Increased trimethylamine-N-oxide (TMAO) levels are pred.

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'Scared to Death': Nurses, Residents Confront Violence in Dementia Care Facilities

Med Page Today

(MedPage Today) -- Dan Shively had been a bank president who built floats for July Fourth parades in Cody, Wyoming, and adored fly-fishing with his sons. Jeffrey Dowd had been an auto mechanic who ran a dog rescue and hosted a Sunday blues radio.

Nursing 94
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Early HCV Treatment Discontinuation Does Not Inhibit Sustained Virologic Response

HCPLive

Findings highlight a 78.4% treatment success rate among patients who prematurely discontinued DAAs, reaching 93.5% among those who discontinued after week 4.

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Routine Protamine Administration for Bleeding in Transcatheter Aortic Valve Implantation

JAMA Cardiology

This randomized clinical trial evaluates the safety and efficacy of administration of protamine to reduce bleeding following transcatheter aortic valve implantation vs placebo, selective protamine administration.

More Trending

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Verinurad Plus Allopurinol for HFpEF

JAMA Cardiology

This randomized clinical trial investigates the effects of verinurad on exercise capacity and symptoms in patients with heart failure with preserved ejection fraction (HFpEF) and elevated serum uric acid levels.

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Study Compares Artificial Intelligence Smartphone Applications for Skin Cancer

HCPLive

This analysis highlights data regarding agreement between various smartphone applications used for detection of melanoma.

Cancer 111
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Mayo Clinic to test AI-powered cardiac imaging

Becker's Hospital Review - Cardiology

"Discover the latest AI-powered cardiac imaging technology, CardiAQ, being tested by Mayo Clinic researchers in collaboration with SandboxAQ.

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Nail Psoriasis Severity, Age at Diagnosis Predict Future Initiation of Biologic Treatment

HCPLive

In this analysis, the biggest predictors of biologic initiation among individuals with diagnoses of psoriasis were evaluated.

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Identification of regulatory networks and crosstalk factors in brown adipose tissue and liver of a cold-exposed cardiometabolic mouse model

Cardiovascular Diabetology

Background Activation of brown adipose tissue (BAT) has gained attention due to its ability to dissipate energy and counteract cardiometabolic diseases (CMDs). Methods This study investigated the consequences of cold exposure on the BAT and liver proteomes of an established CMD mouse model based on LDL receptor-deficient (LdlrKO) mice fed a high-fat, high-sucrose, high-cholesterol diet for 16 weeks.

Diet 52
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Vitamin D Associated With Lower Risk of Mortality in Patients With Gout, Hyperuricemia

HCPLive

The study was not adequately powered to assess a significant association with cancer mortalities.

Cancer 105
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Unusual and very rare presentation of wrist pain in a man with acute anterior myocardial infarction, a case report and literature of review

Journal of Cardiothoracic Surgery

As acute myocardial infarction (AMI) prevalence is increasing because of lifestyle changes, the incidence of atypical symptoms in acute coronary syndrome (ACS) is rising and making misdiagnosing of this fatal.

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Phase 1b Trial Signals Benefit of VLS-01 for Treatment-Resistant Depression

HCPLive

Preliminary Phase 1b data demonstrated the favorable safety and tolerability profile of VLS-01 buccal film, with psychedelic effects resolved by 120 minutes.

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Effects of smoking cessation on endothelial function as assessed by flow-mediated total dilation

Cardiovascular Ultrasound

In assessing the effects of smoking cessation on endothelial function, low-flow-mediated constriction (L-FMC) may provide complementary information to flow-mediated dilation (FMD). However, the value of flow-m.

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FDA Approves Nemolizumab for Treatment of Prurigo Nodularis

HCPLive

The drug is the first approved monoclonal antibody specifically designed to inhibit the IL-31 pathway, a driver of prurigo nodularis.

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SGLT2 Hesitance; Furosemide's Indication Grows; Legal Fight Over Entresto Generic

Med Page Today

(MedPage Today) -- From 2022 to 2023, uptake of SGLT2 inhibitors was low in patients with a class Ia recommendation. (Journal of the American College of Cardiology) In a phase IIa study, the oral controlled metabolic accelerator drug HU6 resulted.

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Measuring Patient Satisfaction with Inflammatory Bowel Disease Treatments and Communication Regarding Treatment Changes

HCPLive

Silvio Danese, MD, PhD; Bruce Sands, MD, and Jean-Frederic Colombel, MD, conclude by sharing their approaches to evaluating patient satisfaction and expectations when providing care for ulcerative colitis and Crohn's disease, while also touching upon the importance of discussing the potential need for escalating or switching therapies to better manage the underlying disease processes.

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Inside the growing use of ECMO in cardiac care

Becker's Hospital Review - Cardiology

The use of extracorporeal membrane oxygenation (ECMO) is continuing to grow, with 77,542 patients in North America receiving the form of life support in the past five years, according to the Extracorporeal Life Support Organization.

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HuMAIN: HU6 Achieves Significant Weight Loss in Obesity-Related HFpEF

HCPLive

Announced by Rivus Pharmaceuticals, HU6 met its primary endpoint of weight reduction in patients with obesity-related HFpEF in a Phase 2a trial.

Obesity 59
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Health Coaching Improves Outcomes of Caregivers of Adults With HF

American College of Cardiology

What is the effect of virtual caregiver support, health coaching intervention on self-care, stress, coping, and perceived mental and physical health status compared with usual care, including receiving health information only?

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Vitrectomy Added to Anti-VEGF Therapy Lacks Benefit for DME

HCPLive

Adding vitrectomy with ILM peeling to a treat-and-extend anti-VEGF therapy showed no benefit on visual or anatomic outcomes in DME treatment.

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Undifferentiated LVH: Pitfalls in the Diagnosis of HCM

American College of Cardiology

In this interview, Timothy C. Wong, MD, MS, FACC and Sidney C. Smith Jr., MD, MACC discuss pitfalls in the diagnosis of HCM.

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Wedge Pressure, Measured Using Cardiac MRI, Can Aid in Predicting Incident Heart Failure

HCPLive

New study suggests MRI-derived pressure measurements indicate a 5-fold increase in heart failure risk.

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Transhepatic Approach for Catheter Ablation of Atrial Fibrillation in Patients with Interrupted Inferior Vena Cava

HeartRhythm

Interruption of the inferior vena cava (IVC) is a rare vascular anomaly resulting from aberrant development during embryogenesis, deep venous thrombosis or extrinsic tumor compression.1 Transhepatic access has been used for cardiac procedures in such individuals, particularly children, though only rare cases of atrial fibrillation (AF) ablation have been reported.2-4 We aimed to describe the procedural steps, safety and efficacy of AF ablation using transhepatic access.

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Humira Biosimilar Added to Costco Member Prescription Program

HCPLive

Adalimumab-aaty was FDA approved on May 23, 2023, and became commercially available in the US on July 2, 2023.

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Efficacy and Clinical Outcomes of Catheter Ablation for Atrial Arrhythmia in Cardiac Amyloidosis

HeartRhythm

Cardiac amyloidosis (CA) involves the abnormal accumulation of misfolded proteins in the heart muscle, leading to restrictive cardiomyopathy.1 Recent advancements in imaging and therapeutic agents have sparked considerable interest in this field. Atrial arrhythmias (AA), particularly atrial fibrillation (AF), are prevalent in CA and may impact long-term cardiovascular outcomes, prompting an investigation into early rhythm management strategies.2 However, a significant gap in understanding the sa

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Kidney and CV Effectiveness of SGLT2 Inhibitors vs. GLP-1 RAs in Diabetes

American College of Cardiology

What are the kidney and cardiovascular (CV) outcomes for new users of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) among people with type 2 diabetes (T2D)?

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In Memoriam: George L. Bakris, MD (1952 to 2024)

Hypertension Journal

Hypertension, Volume 81, Issue 9 , Page e111-e112, September 1, 2024.

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Henry R. Black, MD (1942–2024)

Hypertension Journal

Hypertension, Volume 81, Issue 9 , Page e108-e110, September 1, 2024.