HCPLive
DECEMBER 12, 2024
An FDA review of postmarket clinical trial data revealed an increased risk of liver injury with obeticholic acid in patients with PBC without cirrhosis.
Science Daily - Stroke
DECEMBER 12, 2024
Endovascular therapy, a minimally invasive surgery performed inside the blood vessels, is preferred to alternative approaches for vessel obstructions in life-sustaining areas of the brain, analysis suggests.
HCPLive
DECEMBER 12, 2024
Patients with schizophrenia and COVID-19 both present dysregulated energy metabolism, explaining the high COVID-19 rates among those with schizophrenia.
Science Daily - Heart Disease
DECEMBER 12, 2024
Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be directly attributed to hypertension or other cardiovascular disorders. This often under-diagnosed heart function impairment is one of the leading causes of death in diabetic patients and it affects both type 1 and type 2 diabetes. There is no current specific drug treatment or clinical protocol approved to address this disease.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Med Page Today
DECEMBER 12, 2024
(MedPage Today) -- The non-small cell lung cancer (NSCLC) drug osimertinib (Tagrisso) was associated with an increased risk of therapy-related cardiovascular (CV) events compared with older EGFR inhibitors, a retrospective cohort study from Taiwan.
HCPLive
DECEMBER 12, 2024
The FDA awarded Breakthrough Therapy Designation to Vir Biotechnologys tobevibart and elebsiran for the treatment of chronic hepatitis delta.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HCPLive
DECEMBER 12, 2024
To celebrate surpassing 100 episodes, Diabetes Dialogue sits down with Irl Hirsch, MD, to discuss the 25-year anniversary of continuous glucose monitoring in 2024.
Medical Xpress - Cardiology
DECEMBER 12, 2024
Cardiovascular problems are the leading cause of disease and mortality worldwide. Plant extracts, rich in bioactive compounds, have contributed significantly to the development of drugs, as they offer therapeutic potential for several of these diseases. However, their use is limited by possible side effects, drugdrug interactions and the lack of scientific evidence from quality preclinical and clinical studies.
HCPLive
DECEMBER 12, 2024
A study shows constipation has a causal relationship with schizophrenia and MDD, but the relationship with schizophrenia may have limited clinical implications.
Ken Grauer, MD
DECEMBER 12, 2024
I was sent the ECG in Figure-1 initially told only that it was obtained from an older man with palpitations. The cardiology team thought the rhythm was an SVT ( S upra V entricular T achycardia ) with QRS widening as a result of aberrant conduction. QUESTION: Do YOU agree that the rhythm is consistent with an SVT , in which there is QRS widening because of aberrancy?
HCPLive
DECEMBER 12, 2024
Patients with IBS had different dietary patterns than matched general population controls, with poor diet diversity and quality linked to symptom severity.
Medical Xpress - Cardiology
DECEMBER 12, 2024
Endovascular therapy, or EVT, a minimally invasive surgery performed inside the blood vesselsis 2 times more likely than standard medical management to achieve a positive outcome after vertebrobasilar stroke that affects the back of the brain, including the brain stem.
Stroke Journal
DECEMBER 12, 2024
Stroke, Ahead of Print. Considerable variation exists in the delivery of acute stroke care and stroke outcomes across settings and population groups. This is attributable in part to variation in resources among emergency departments in the United States, most notably in rural regions. Structural constraints of the US health care system, including the geographic distribution of where patients live relative to the location of hospitals and certified stroke centers, will continue to mean that many
Medical Xpress - Cardiology
DECEMBER 12, 2024
An investigation published in The BMJ raises new concerns over the landmark clinical trial (PLATO) that was used to gain worldwide approval for the anti-platelet drug ticagrelor (Brilinta in the US and Brilique in Europe), manufactured by AstraZeneca.
HCPLive
DECEMBER 12, 2024
This assessment of dupilumab for pediatric and adult patients with moderate-to severe eczema treated for up to 5 years confirms the drug efficacy and safety across age groups.
Medical Xpress - Cardiology
DECEMBER 12, 2024
A large study found that greater exposure to long-term air pollution was linked with increased risks for blood clots that can occur in deep veins, which, if untreated, can block blood flow and cause serious complications, even death.
HCPLive
DECEMBER 12, 2024
These long-term results from the ADjoin trial show that long-term lebrikizumab therapy may improve sleep disturbances, pruritus, and skin symptoms, using POEM as an assessment tool.
Frontiers in Cardiovascular Medicine
DECEMBER 12, 2024
It is unusual for young patients without any underlying diseases to experience sudden cerebral infarction and heart failure. Here, we report a rare case of a 28-year-old female patient who presented with chest tightness and dizziness. Left ventricular thrombus formation and cardiac insufficiency were evident on echocardiogram, while multiple acute or subacute cerebral infarctions were visible on brain magnetic resonance imaging.
HCPLive
DECEMBER 12, 2024
America's mental health crisis continues to escalatewhat drives it, and what lies ahead in 2025? Hear insight from psychiatry and psychology experts.
Frontiers in Cardiovascular Medicine
DECEMBER 12, 2024
BackgroundCoronary artery bypass grafting (CABG) surgery has been a widely accepted method for treating coronary artery disease. However, its postoperative complications can have a significant effect on long-term patient outcomes. A retrospective study was conducted to identify before and after surgery that contribute to postoperative stroke in patients undergoing CABG, and to develop predictive models and recommendations for single-factor thresholds.Materials and methodsWe utilized data from 1,
Med Page Today
DECEMBER 12, 2024
(MedPage Today) -- NEW ORLEANS -- Tenecteplase in recent years outpaced alteplase as the stroke thrombolytic of choice at one large hospital system, despite shrinking cost savings, a researcher reported here. In 2021, clinicians at Cardinal.
Frontiers in Cardiovascular Medicine
DECEMBER 12, 2024
BackgroundThe association between healthy lifestyle and American Heart Association (AHA) Life's Essential 8 (LE8) score and apparent treatment-resistant hypertension(aTRH)remains uncertain. We aimed to explore the association between healthy lifestyle and higher LE8 score and apparent treatment-resistant hypertension in the general population.MethodsUsing NHANES data from 2005 to 2018, we included and analyzed information on 7,474 participants eligible for this study.
HCPLive
DECEMBER 12, 2024
Patients with hypercortisolism and difficult-to-control type 2 diabetes who received mifepristone exhibited a significant HbA1c improvement in the Phase 4 trial.
Becker's Hospital Review - Cardiology
DECEMBER 12, 2024
Salt Lake City-based Intermountain Health's St. Mary's Regional Hospital in Grand Junction, Colo., recently became the first community hospital in the nation to receive vascular verification from the American College of Surgeons and the Society for Vascular Surgery.
HCPLive
DECEMBER 12, 2024
Elevated blood insulin levels and insulin resistance each contributed to an elevated risk of colorectal cancer, a new study finds.
Becker's Hospital Review - Cardiology
DECEMBER 12, 2024
New York City-based NYU Langone has expanded cardiology services at the NYU Langone HospitalBrooklyn. Previously, NYU Langone patients living in Brooklyn were travelling to Manhattan to receive advanced cardiac care.
HCPLive
DECEMBER 12, 2024
The BCG-unresponsive non-muscle invasive bladder cancer space has gone from a dearth of options to a wave of new treatments.
Becker's Hospital Review - Cardiology
DECEMBER 12, 2024
After CMS released its finalized 2025 physician fee schedule, which will reduce reimbursements by 2.83%, some cardiologists are raising concerns over what they call an unstable healthcare system, according to a Dec. 9 TCTMD report.
American College of Cardiology
DECEMBER 12, 2024
The goal of the TRILUMINATE Pivotal trial was to evaluate percutaneous tricuspid valve transcatheter edge-to-edge repair (TEER) compared with medical therapy among patients with symptomatic severe tricuspid regurgitation.
Becker's Hospital Review - Cardiology
DECEMBER 12, 2024
Women in academic cardiothoracic surgery earn 80% to 87% of the salary men with equal academic rank earn, according to a study published Dec. 2 in The Annals of Thoracic Surgery.
American College of Cardiology
DECEMBER 12, 2024
Presenting and learning from real-world accountable care cardiovascular arrangements was the focus of ACCs sixth annual Value-Based Care in Cardiology Forum, held Dec. 5 in Washington, DC.
HeartRhythm
DECEMBER 12, 2024
The autonomic nervous system, through the ganglionated plexus (GP), is known to contribute to the arrhythmogenesis of atrial fibrillation (AF). The GANGLIA-AF trial was a prospective, multicenter, randomized, single-blinded study (NCT02487654) randomizing paroxysmal AF patients to either stand-alone left atrial ectopy-triggering GP (ET-GP) ablation or standard pulmonary vein isolation (PVI) only.1 The trial was unique in that it performed detailed mapping of the left atrium, surveying for sites
American College of Cardiology
DECEMBER 12, 2024
The U.S. Senate passed the Cardiomyopathy Health Education, Awareness, Research, and Training in the Schools (HEARTS) Act (H.R. 6829), a major ACC Advocacy priority, on Dec. 10. The bill secures funding for cardiomyopathy awareness initiatives and supporting the placement of AEDs in schools, along with CPR and AED training.
HeartRhythm
DECEMBER 12, 2024
Early recurrences of atrial tachyarrhythmias (ERATs) after pulmonary vein isolation (PVI) are common. While many correlate to late recurrences (LRs), some do not. The impact of ERAT timing is difficult to assess with noninvasive Holter monitoring because of undersampling. The recommended duration of the blanking period (BP) was recently shortened from 90 days to 8 weeks.
Journal of Cardiovascular Electrophysiology
DECEMBER 12, 2024
ABSTRACT Introduction Left atrial appendage aneurysm (LAAA) is a rare congenital cardiac anomaly that involves the progressive dilatation of the left atrial appendage (LAA), predisposing the patient to serious complications such as atrial tachyarrhythmias, life-threatening systemic thromboembolism, and cardiac dysfunction. Methods and Results We described a case of a 36-year-old woman with incessant atrial tachycardia (AT) originating from LAAA, which surgical intervention successfully terminate
HeartRhythm
DECEMBER 12, 2024
Congenital long QT syndrome (LQTS) is characterized by delayed ventricular repolarization, predisposing to potentially lethal ventricular arrhythmias. The variability in disease severity among patients remains largely unexplored, underscoring the limitations of current risk stratification methods.
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