Thu.Sep 05, 2024

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Up to 1 in 5 Dementia Cases May Be Attributable to Vision Impairment

Med Page Today

(MedPage Today) -- Up to one in five prevalent dementia cases may be attributable to impaired vision, a cross-sectional analysis suggested. In a study of nearly 2,800 older Americans, the population attributable fraction (PAF) of prevalent dementia.

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Why the sudden shock after a few days of malaise?

Dr. Smith's ECG Blog

Written by Magnus Nossen - Edits by Grauer and Smith The patient in today’s case is a woman in her 70s with a previous medical history of HTN and hyperlipidemia. She presented to an outside hospital after several days of malaise and feeling unwell. At the time of admission, her vital signs were normal. Heart rate was in the 80s. She had a very elevated troponin T at 12,335 ng/L at the time of presentation. ( This is a value typical for a large subacute MI, n ormal value 48 hours after myocardial

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Study estimates home blood pressure devices don't fit properly for more than 17 million US adults

Science Daily - Heart Disease

Over-the-counter blood pressure measuring devices offer a simple, affordable way for people to track hypertension at home, but the standard arm-size ranges for these devices won't appropriately fit millions of U.S. consumers, according to a new study.

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Remote monitoring and pharmacist helped improve hard-to-control blood pressure

American Heart News - Heart News

Research Highlights: A new study finds that up to 74% of participants with resistant or difficult-to-control high blood pressure, including those with chronic kidney disease, were able to improve control of their blood pressure within 12 months after.

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Thomas A. Wadden, PhD: Semaglutide Not Linked to Increased Depression Risk

HCPLive

In an interview with HCPLive, Wadden discussed the findings of a post-hoc analysis, supporting how semaglutide is not linked to an increased suicidal ideation risk.

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High blood pressure a concern for adolescents and young adults in U.S.

American Heart News - Heart News

Research Highlights: In the first study, nearly 23% of young adults (ages 18-39 years) included in the NHANES 2017-2020 datasets had high blood pressure (130/80 mm Hg or greater). In addition, they were more likely to self-report being uninsured, food.

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Researchers discover new insights into the neurobiological origins of ataxia

Science Daily - Stroke

A study investigated the origin of ataxia in the brain of patients with stroke. A significant number of the stroke lesions in the patients were located outside the cerebellum.

More Trending

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FDA Approves Travere Therapuetics’ Sparsentan for Proteinuria Reduction in Adult Primary IgAN

HCPLive

The FDA has granted full approval to sparsentan (Filspari) for reducing proteinuria in adults with IgAN at risk of rapid disease progression based on PROTECT trial data.

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Popular home blood pressure monitoring cuff devices may not fit some US adults

American Heart News - Heart News

Research Highlights: An analysis of at-home blood-pressure monitors estimates that the arm cuffs for 10 of the most popular potentially do not fit up to 18 million adults in the U.S. and nearly 12% of Black adults. To ensure accurate blood pressure.

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Study shows long term-effects of immigration on Chinese Americans' cardiovascular health

Science Daily - Heart Disease

A new study found that cardiovascular disease risk among Chinese American immigrants increases with length of residence and varies by location in the U.S.

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Prediction of sudden cardiac death using artificial intelligence: Current status and future directions

HeartRhythm

Sudden cardiac death (SCD) remains a pressing health issue, affecting hundreds of thousands each year globally. The heterogeneity among SCD victims, ranging from individuals with severe heart failure to seemingly healthy individuals, poses a significant challenge for effective risk assessment. Conventional risk stratification, which primarily relies on left ventricular ejection fraction, has resulted in only modest efficacy of implantable cardioverter-defibrillators (ICD) for SCD prevention.

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Impact of C-Reactive Protein, LDL Cholesterol, and Lipoprotein(a) on Long-Term Cardiovascular Risk in Women

NEJM Journal Watch - Cardiology

During 30 years of follow-up, all three biomarkers significantly and independently predicted incidence of a major adverse cardiovascular event in women.

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2024 ESC Guidelines for Management of Elevated BP and Hypertension: Key Points

American College of Cardiology

The following are key points to remember from the 2024 European Society of Cardiology (ESC) guidelines for the management of elevated blood pressure (BP) and hypertension.

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New Insight: A Look at Corneal Transplant Alternatives w/ John Sheets, PhD

HCPLive

Host Veeral Sheth, MD is joined by John Sheets, PhD, the president, CEO, and co-founder of Pantheon Vision, an early research-stage organization working to develop bioengineered solutions to eliminate corneal blindness.

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Abnormal expression of circ_0013958 in patients with acute myocardial infarction (AMI) and its influence on prognosis

Journal of Cardiothoracic Surgery

The purpose of this study was to investigate the diagnostic value of circ_0013958 in acute myocardial infarction (AMI) patients and its influence on the prognosis of AMI patients.

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Nephrology Month in Review: August 2024

HCPLive

The August 2024 month in review highlights our coverage of pipeline news, a cross-specialty feature about dialysis, and other recent renal news and research from the past few weeks.

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Balloon Angioplasty 'Lite' Improves Key Intracranial Stenosis Outcomes

Med Page Today

(MedPage Today) -- Submaximal balloon angioplasty for symptomatic intracranial atherosclerotic stenosis (ICAS) improved outcomes over aggressive medical management alone, the BASIS trial from China showed. The incidence of the composite of any.

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Error Rates in Race and Ethnicity Designation Detected in Pediatric Records

HCPLive

A study found high error rates in racial and ethnic designations in pediatric health records across 3 Michigan hospitals, risking misinformed care strategies.

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5 Ways Employers Can Embrace a Human-Centered Design in Healthcare

Learning + Leading

In the dynamic landscape of healthcare, the imperative for a human-centered design has never been so high. Employers are continuously challenged with staffing shortages and burnout among healthcare workers. Concurrently, patients are increasingly vocal about their care experiences, articulating concerns such as long wait times, insufficient provider interaction, and a lack of personalized care.

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Rheumatology Month in Review: August 2024

HCPLive

The rheumatology month in review emphasize's bimekizumab's efficacy in treating PsA and new risk factors and mitigators for developing gout or hyperuricemia.

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Remote monitoring, pharmacy support improve patients' blood pressure: Study

Becker's Hospital Review - Cardiology

A program combining remote monitoring and pharmacist support improved blood pressure in 74% of patients whose blood pressure was previously resistant to treatment.

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Daily Vadadustat Equal to Darbepoetin Alfa for Anemia in Dialysis-Dependent CKD

HCPLive

Vadadustat once-daily demonstrated noninferiority to darbepoetin alfa for the change in mean hemoglobin from baseline, while 3-times-weekly did not.

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ACC Submits Comments on 2025 Hospital OPPS Proposed Rule

American College of Cardiology

The ACC submitted formal comments to the Centers for Medicare and Medicaid Services (CMS) on Sept. 4, providing feedback and raising concerns on several issues of relevance to the cardiovascular community in the 2025 Hospital Outpatient Prospective Payment System (OPPS) proposed rule.

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Advanced Treatment Options for RA: Exploring the Data

HCPLive

Panelists discuss advanced treatment options for rheumatoid arthritis, focusing on the SELECT-COMPARE trial's head-to-head data of upadacitinib versus adalimumab, the use of upadacitinib in active RA refractory to biologics (SELECT-BEYOND trial), and the remission rates of upadacitinib compared to abatacept (SELECT-CHOICE trial).

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A new heart disease risk factor

Becker's Hospital Review - Cardiology

New study reveals clonal hematopoiesis as a significant risk factor for heart disease.

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Guiding Treatment Decisions: The Role of Remission Data and Head-to-Head Comparisons

HCPLive

Panelists discuss how head-to-head clinical trial data shape their treatment decisions, the significance of consistent remission rates across different patient populations, and the frequency with which remission data influence their choices to switch therapies.

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Efficacy and Safety of Early Post-Operative Ablation in Patients with Congenital Heart Disease

HeartRhythm

Post-operative arrhythmias are most often transient and medically treated, but some patients may require electrophysiology study (EPS) and ablation.

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ESC Congress Recap: High-Impact Clinical Trials, with Deepak Bhatt, MD, MPH, MBA

HCPLive

Deepak Bhatt, MD, MPH, MBA Bhatt a group of 4 high-impact studies from ESC Congress 2024: FINEARTS-HF, ABYSS, RESHAPE-HF2, and SHAM-PVI.

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Bivalirudin in Extracorporeal Membrane Oxygenation

Journal of Cardiovascular Pharmacology

Abstract: Extracorporeal membrane oxygenation (ECMO) is a mechanical support treatment modality utilized in patients with refractory cardiac and/or pulmonary failure. Bleeding and thrombotic complications associated with ECMO are inherent concerns that require careful management. Anticoagulation optimization may help mitigate these risks by providing more adequate therapeutic anticoagulation and lessen the bleed risk.

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Survey Provides Updated Expert Opinions on Severe AATD Assessment, Monitoring

HCPLive

The Delphi survey collected opinions from members of the European Alpha-1 Research Collaboration to guide the diagnosis, treatment, and management of severe AATD.

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Atrial resynchronization with Bachmann’s bundle pacing - time to think outside the appendage?

HeartRhythm

In contrast to the intense interest in physiologic ventricular pacing over the last decade, the location of atrial pacing leads has received surprisingly little attention. The right atrial appendage, initially used because of the ability to obtain stable fixation of tined leads, remains the default option for almost all implants. Various locations in the right atrium, dual site right atrial, and biatrial pacing of the right and left atria have all been investigated, without showing a consistent

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Key Findings Presented from Largest Multinational Real-World Chronic Hand Eczema Studies

HCPLive

These data were presented at the European Society of Contact Dermatitis congress, with findings drawn from the CHECK and RWEAL studies on chronic hand eczema.

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Procedural and Long-Term Outcomes of Tunneled Transvenous Leads

HeartRhythm

Lead-related venous stenosis and occlusion can complicate the insertion or replacement of transvenous leads in patients with cardiac implantable electronic devices (CIED). A possible solution is to tunnel the lead from the contralateral vasculature to the ipsilateral generator. Procedural complications and long term outcomes remain unclear with this technique.

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Incidence, time course, and outcomes of worsening tricuspid regurgitation following transvenous cardiac implantable electronic device implantation

The American Journal of Cardiology

Publication date: Available online 4 September 2024 Source: The American Journal of Cardiology Author(s): Kitae Kim, Ryosuke Murai, Taiji Okada, Toshiaki Toyota, Yasuhiro Sasaki, Tomohiko Taniguchi, Natsuhiko Ehara, Atsushi Kobori, Makoto Kinoshita, Yutaka Furukawa

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Secukinumab Biosimilar Demonstrates Pharmacokinetic Equivalence

HCPLive

Participants in a study in China also experienced comparable safety and immunogenicity.

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“The Belgian Registry on Coronary Function Testing (BELmicro Registry): Study Population, Prevalence of Coronary Vascular Dysfunction and Procedural Safety.”

The American Journal of Cardiology

Publication date: Available online 4 September 2024 Source: The American Journal of Cardiology Author(s): Tijs Bringmans, Alice Benedetti, Carlo Zivelonghi, Maarten Vanhaverbeke, Frédéric Daniel Mathieu, Pieter-Jan Palmers, Patrick Coussement, Kenneth De Wilder, Bert Everaert, Mathieu Coeman, Fabian Demeure, Maarten Kersemans, Carlos Collet Bortone, Peter Kayaert, Carlos Van Mieghem, Vincent Frans Maria Segers

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Should We Perform Up-Front PCI in Patients with Significant Coronary Disease Undergoing TAVR?

NEJM Journal Watch - Cardiology

New randomized trial findings suggest limiting this strategy to patients with the most severe disease.

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