Sat.Nov 11, 2023

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Instructors' Collection ECG: Isolated Posterior Wall M.I.

ECG Guru

This interesting case was provided by Dr. Bojana Uzelac, Emergency Medicine physician. We are paraphrasing a translation of her comments here. The patient is a 50-year-old complaining of chest pain. The ECG shows a rare occurrence – an isolated POSTERIOR WALL MI (PWMI). Note that leads V1 through V4 show the usual signs of posterior wall MI. We see ST segment depression, which represents a reciprocal view of the ST elevation present on the posterior wall of the left ventricle.

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A 90-something with acute stroke. She has no chest symptoms. What is the diagnosis?

Dr. Smith's ECG Blog

A 90-something year old woman presented with an acute mild stroke. She had a routine ECG as part of her workup: What do you think? This was shown to me in real time. I thought it had to be an inferior-lateral-posterior OMI. But the patient had no symptoms. Later, she did admit to some vague chest discomfort, but that could be due to the power of suggestion.

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Major CVD event risk cut by 20% in adults without diabetes, with overweight or obesity

American Heart News - Heart News

Research Highlights: In a large, international clinical trial, people with obesity or overweight but not diabetes taking semaglutide for more than 3 years had a 20% lower risk of heart attack, stroke or death due to cardiovascular disease and lost an.

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Combatting Pneumonia: A Global Call to Action on World Pneumonia Day

ADN Center of Excellence

As healthcare professionals dedicated to advancing medical knowledge and patient care, it's crucial for us to stay informed about prevalent health issues. World Pneumonia Day, observed on November 12th each year, serves as a poignant reminder of the ongoing battle against this respiratory infection. In this blog, we'll explore key aspects of pneumonia, its global impact, and how our collective efforts can make a difference.

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Red blood cell transfusions may improve outcomes in heart attack patients with anemia

American Heart News - Heart News

Research Highlights: A multinational trial compared examined outcomes in heart attack patients with anemia who received blood transfusions when their hemoglobin concentration levels were at 8 g/dL or 10 g/dL. While results did not reach statistical.

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Festive Greetings from India

Dr. S. Venkatesan MD

Di wali is celebrated today November 12 th, as “Festival of lights” an Important spiritual event in India, On this day, we pray God, knowledge, goodness, and peace replace Ignorance, evil and turbulence in this world.

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Lowering blood pressure significantly reduced dementia risk in people with hypertension

American Heart News - Heart News

Research Highlights: A four-year blood pressure intervention program in rural China significantly reduced systolic blood pressure by an average of 22 mmHg and risk of all-cause dementia by 15% in people with high blood pressure. Trained.

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Improving blood pressure control after pregnancy had long-term cardiovascular benefits

American Heart News - Heart News

Research Highlights: Women with high blood pressure during pregnancy had lower blood pressure nine months later if their blood pressure was more tightly controlled the first few weeks after delivery, compared to women who received usual postpartum.

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Combatting Pneumonia: A Global Call to Action on World Pneumonia Day

ADN Center of Excellence

As healthcare professionals dedicated to advancing medical knowledge and patient care, it's crucial for us to stay informed about prevalent health issues. World Pneumonia Day, observed on November 12th each year, serves as a poignant reminder of the ongoing battle against this respiratory infection. In this blog, we'll explore key aspects of pneumonia, its global impact, and how our collective efforts can make a difference.

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Reducing sodium intake significantly lowered blood pressure in as little as one week

American Heart News - Heart News

Research Highlights: A randomized trial comparing the effects of high-sodium and low-sodium diets on blood pressure in adults with normal blood pressure and high blood pressure found that following a low-sodium diet significantly lowered blood.

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What Lies beneath the Surface — Treatment of Subclinical Atrial Fibrillation

The New England Journal of Medicine

Continuous heart rhythm monitoring with cardiac implantable devices has shown that atrial tachyarrhythmias, termed high-rate episodes (AHREs), occur in approximately one third of device carriers.1,2 AHRE definitions vary across studies, but cutoffs of an intracardiac atrial frequency of at least 180 bpm with a duration of 5 minutes.

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Dapagliflozin and eGFR Decline in HFmrEF/HFpEF

JAMA Cardiology

This prespecified analysis of the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) randomized clinical trial investigates the association of initial changes in estimated glomerular filtration rate with cardiovascular and kidney outcomes in patients with heart failure and mildly reduced or preserved ejection fraction.

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Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

The New England Journal of Medicine

In a randomized trial involving patients with subclinical (typically asymptomatic) atrial fibrillation, apixaban led to a lower risk of stroke or systemic embolism than aspirin but a higher risk of major bleeding.

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Ivabradine in the Management of Elevated Resting Heart Rate Associated with Mediastinal Radiation Therapy

HeartRhythm

Mediastinal radiation therapy (RT) can lead to autonomic dysfunction and elevated resting heart rates (HR) that limit exercise capacity in Hodgkin lymphoma (HL) survivors 1. Funny (If) channels in the cardiac sino-atrial node mediate autonomic modulation of HR and can be altered in various disease states 2. This pilot study explored whether ivabradine, a specific If inhibitor, can lower HR and improve exercise capacity in RT-treated lymphoma survivors with elevated resting HR.

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Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials

Circulation

Circulation, Ahead of Print. Background:Device-detected atrial fibrillation (AF) (also known as subclinical AF or atrial high-rate episodes) is a common finding in patients with an implanted cardiac rhythm device and is associated with an increased risk of ischemic stroke. Whether oral anticoagulation is effective and safe in this patient population is unclear.Methods:We performed a systematic review of MEDLINE and Embase for randomized trials comparing oral anticoagulation to antiplatelet or no

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Estimated Lifetime Cardiovascular, Kidney and Mortality Benefits of Combination Treatment With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Non-steroidal MRA Compared With Conventional Care in Patients With Type 2 Diabetes and Albuminuria

Circulation

Circulation, Ahead of Print. Background:Sodium glucose co-transporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1 RA), and the non-steroidal mineralocorticoid receptor antagonist (MRA) finerenone all individually reduce cardiovascular, kidney and mortality outcomes in patients with type 2 diabetes and albuminuria. However, the lifetime benefits of combination therapy with these medicines are not known.Methods:We used data from 2 SGLT2i trials (CANVAS and CREDENCE), 2

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Effects of Semaglutide on Symptoms, Function, and Quality of Life in Patients with Heart Failure with Preserved Ejection Fraction and Obesity: A Prespecified Analysis of the STEP-HFpEF Trial

Circulation

Circulation, Ahead of Print. Background:Patients with heart failure (HF) with preserved ejection fraction (HFpEF) and obesity experience high burden of symptoms and functional impairment, and a poor quality of life. In the STEP-HFpEF trial, once-weekly semaglutide 2.4 mg improved symptoms, physical limitations and exercise function, and reduced inflammation and body weight.

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A Complex Anterior Mediastinal Mass in a Young Adult

Circulation

Circulation, Ahead of Print.

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Cardiac Remodeling After Hypertensive Pregnancy Following Physician-Optimized Blood Pressure Self-Management: The POP-HT Randomized Clinical Trial Imaging Sub-study

Circulation

Circulation, Ahead of Print. Background:Hypertensive pregnancy disorders are associated with adverse cardiac remodeling, which can fail to reverse postpartum in some women. The Physician Optimized Postpartum Hypertension Treatment trial demonstrated improved blood pressure control, while the cardiovascular system recovers postpartum, associates with persistently reduced blood pressure.