Sun.Dec 31, 2023

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Amal Mattu’s ECG Case of the Week – January 1, 2024

ECG Weekly Workout

HPI: A 50-year-old man decides to get “his life in order” for the new year. He quits smoking, decides to eat healthier and exercise more, and to be more compliant with his blood pressure medications. A week into the new year he wakes up feeling weak and achy with nausea and vomiting. He is lightheaded when sitting or standing and has trouble getting out of bed.

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Faricimab Provides Similar nAMD, DME Outcomes at Significantly Fewer Injections

HCPLive

A systematic review and meta-analysis suggests the dual pathway-targeting faricimab provides some greater benefit in outcomes like CST at fewer injections and without compromise of safety to anti-VEGF monotherapies.

Outcomes 108
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What I learned from writing my most-read ‘Heart Sisters’ articles in 2023

Heart Sisters

The most-popular HEART SISTERS posts from 2023 were all over the map - from 'Struggle Care' to sweating, hanging up that iconic Red Dress, or cardiac arrest on the toilet!

Article 87
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Happy New Year from the DAIC Team

DAIC

The Diagnostic and Interventional Cardiology (DAIC) team wish you a happy, healthy and prosperous New Year!

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Rise of COVID's JN.1 Sub variant Cases in India in 2023

Wellnest

On Sunday, the nation reported 841 new instances of COVID-19, marking the most substantial daily increase in over 10 months. As India concludes 2023, the final fortnight of December has witnessed nearly 8,500 Covid-19 cases. There is a heightened awareness of caution as Covid-19 resurfaces during winter. The JN.1 is a sub-variant recently developed from the BA.2.86 (also known as Pirola.

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Biosimilar Market Share Greater in Medicare Advantage Versus Part B

HCPLive

Analysis shows that biosimilar uptake was up to 2-fold greater in Medicare Advantage coverage than traditional Medicare.

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Cardiac denervation and its consequences in heart disease

HeartRhythm

We have read the article by Chung W et al (1) with great interest. Their experimental findings highlight the risk of ventricular proarrhythmia after cardioneuroablation, a significant concern that dates back to the description of the technique. Although considered safe in healthy individuals (2), the vagal attenuation effect has not been specifically evaluated in heart disease patients yet, and its impact on this particular population is therefore, unknown.

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First conclusive evidence that the implantable cardioverter-defibrillator reduces total mortality compared with drugs

HeartRhythm

This 1997 figure is the first conclusive evidence that the implantable cardioverter-defibrillator (ICD) reduces overall mortality compared with drugs in patients with life-threatening ventricular arrhythmias (from The New England Journal of Medicine, reprinted with permission from Massachusetts Medical Society).1 The story behind the figure is presented.

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Challenging the Paradigm of Post-Capillary Pulmonary Hypertension

The American Journal of Cardiology

Publication date: Available online 30 December 2023 Source: The American Journal of Cardiology Author(s): Tanmay Gokhale, Matthew E.

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Top stories on Brugada syndrome

HeartRhythm

Ever since its early descriptions in the late 80s and early 90s of the previous century, Brugada syndrome (BrS) has been surrounded by debates. Is it therefore not surprising that a continuous flow of research papers (250–300 per year during the last decade) deal with these aspects of this intriguing disease.

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Long-Term Clinical and Echocardiographic Outcomes After the Ross Procedure

JAMA Cardiology

This post hoc analysis of a randomized clinical trial assesses long-term survival after the Ross procedure among adults.

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Risk stratification in pediatric hypertrophic cardiomyopathy

HeartRhythm

There has been a recent surge of interest in efforts to refine the risk stratification for sudden cardiac death (SCD) in children and adolescents with hypertrophic cardiomyopathy (HCM).

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Innovation: A mindset for change

HeartRhythm

Innovation is a concept that has been an important part of the medical community for centuries. Improvements in technology and devices and pharmaceutical therapies have long depended on teams focused on innovative thinking. Institutions and companies devote significant portions of their staff and budgets toward developing and designing innovations. Methodologies have been developed to accelerate the innovative process, and architects even design spaces to support creative and collaborative activ

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Advances in understanding of cardiac sodium channel structure/function and their relation to disease pathogenesis and treatment

HeartRhythm

The cardiac voltage-gated sodium channel Nav1.5 plays a critical role in maintaining normal cardiac excitability. Nav1.5, the primary cardiac Nav α-subunit, has been extensively implicated in the etiology of arrhythmias. Indeed, dysfunctions in Nav1.5 due to congenital or acquired defects have been associated with a wide range of pathologic manifestations, including sinus nodal dysfunction, atrial and ventricular arrhythmias, and heart failure.

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Welcome to HeartRhythm 2024

HeartRhythm

It is with great excitement that the new team of Editors begins steering the Journal in January 2024. This happens precisely 20 years after the first page of the Journal was written by Doug Zipes, its Founding Editor.1 Our objective remains the same: To publish the best articles on cardiac electrophysiology (EP) and pacing as rapidly as possible.

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UltraSOUND-based characterization of ventricular tachycardia SCAR and arrhythmogenic substrate: The SOUNDSCAR study

HeartRhythm

Intracardiac echocardiography (ICE) represents a valuable image integration technique, with the unique advantage of dynamic real-time scar characterization.

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Author's reply to Cardiac Denervation and its consequences in heart disease

HeartRhythm

We appreciate Rivarola et al’s thorough review of our paper1.