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Cleveland Clinic researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study published in Nature Communications found that phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.
(MedPage Today) -- A disproportionality analysis based on reports in a World Health Organization (WHO) database suggested a suicidal ideation signal with the GLP-1 receptor agonist semaglutide (Ozempic, Rybelsus, Wegovy). Between 2000 and 2023.
Researchers from Brigham and Women's Hospital have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Cardiovascular disease is the leading cause of death in patients suffering from lupus, an autoimmune disease in which our immune system attacks our own tissues and organs, the heart, blood, lung, joints, brain, and skin. Lupus myocarditis—inflammation of the heart muscle—can be very serious because the inflammation alters the regularity of the rhythm and strength of the heartbeat.
Platelets are circulating cell fragments known to clump up and form blood clots that stop bleeding in injured vessels. Cardiologists have long known that platelets can become "hyperreactive" to cause abnormal clotting that blocks arteries and contributes to heart attack, stroke, and poor blood flow (peripheral artery disease) in the legs of millions of Americans.
Estimates based on NHANES data suggest 15.6 million US adults have used a potentially hepatotoxic botanical herbal and dietary supplement product within the past 30 days.
This cohort study analyzes data for 560 patients newly diagnosed with systemic AL amyloidosis to assess the differences between biomarkers, echocardiography, and cardiovascular magnetic resonance with extracellular volume mapping in characterizing cardiac amyloid infiltration.
Researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study found phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.
A woman in her mid-20s presented with acute fever, chest pain, and exertional dyspnea. Electrocardiogram results showed sinus tachycardia, QRS widening, low-voltage complexes, and ST-segment elevation. What would you do next?
Researchers have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.
(MedPage Today) -- In a highly publicized case, a former Denver cardiologist was found guilty of 35 out of 38 counts of sexual assault related to women he met on dating apps, continuing as recently as 2023. Google announced that Loss of Pulse.
Researchers have uncovered a genetic link between heart disease and Alzheimer's, according to a study published Aug. 13 in the International Journal of Molecular Sciences.
Stretching and meditation both reduced cramp severity and improved sleep quality with no significant differences. However, patients preferred stretching.
A 50 y/o Male presented to the ED with new-onset chest discomfort. He reported no pertinent history (eg, HTN, HLD, DM, Smoking, etc). The initial Trop I returned <0.012 ng/mL. Here is the time-zero ECG. The critical features that immediately caught my attention were both the hyperacute T-wave in aVL, and the reciprocal down-up T-wave in III.
A new recommendation statement cites a lack of current evidence to assess the benefits of iron deficiency screening and supplementation in pregnant individuals.
The risk of early heart failure after heart transplantation is lower if the donor heart is stored in a so-called heart-in-a-box instead of in the usual cooler with ice.
Can a 2-hour (0 and 2 hours) point-of-care (POC) high-sensitivity cardiac troponin I (hs-cTnI) strategy be safely applied in emergency patients with suspected acute myocardial infarction (AMI)?
In this Lungcast episode, Mora and Sadeameli highlight Asthma Action Plans as well as Asthma Peak Weak considerations for children in the new school year.
In this interview, Raul Santos MD, PhD, and Sun Moon Kim MD, FACC discuss strategies to lowering an elevated Lp(a) based on current evidence and available treatments.
Results suggest paternal hepatitis B virus infection prior to pregnancy is associated with a 40% increased risk of congenital heart diseases in their children.
This research evaluates the effect of balloon pulmonary angioplasty (BPA) on cardiac electrophysiological changes in patients with chronic thromboembolic pulmonary hypertension (CTEPH).
Atherosclerosis, a major cause of mortality worldwide, involves an overgrowth of vascular smooth muscle cells in the blood vessels, constraining blood flow and potentially causing cardiovascular diseases.
Investigators with the Smidt Heart Institute at Cedars-Sinai have developed an artificial intelligence (AI) program to detect the presence and severity of mitral valve regurgitation, the most common heart valve disorder.
Guidelines in cardiology continue to evolve as technology and research advance. Cardiologists from two leading health systems in the U.S. spoke to Becker's about their reactions to recent guideline updates.
Becker's has compiled a list of the hospitals with the highest and lowest payments for heart failure cases, as based on CMS's payment provider database.
This ECG was emailed to me by Sam Ghali. (@EM_RESUS) "What do you think, Steve? 69 year old woman with chest pain.” What do you think? I responded: " Suggestion of inferior OMI, but not quite diagnostic." There is an incomplete RBBB. There is minimal STE in lead III with an inverted T-wave, suggesting acute MI with some degree of reperfusion. Same in aVF.
Hypertension, Ahead of Print. BACKGROUND:To understand the role of hypertensive disorders of pregnancy (HDP), including preeclampsia and gestational hypertension (GH), in brain health earlier in life, we investigated the association of HDP with midlife cognition and brain health.METHODS:We studied a prospective cohort of women, baseline age 18 to 30 years, who were assessed at study years 25 and 30 with a cognitive battery and a subset with brain magnetic resonance imaging.
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