Mon.Feb 10, 2025

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Clinical Study Highlights Research on AI that Takes on Cardiopulmonary Killer

DAIC

tim.hodson Mon, 02/10/2025 - 12:43 Feb. 6, 2025 Eko Health, a leader in applying artificial intelligence (AI) for the early detection of heart and lung diseases, recently announcedpublication of a peer-reviewed study evaluating its novel algorithm for the detection of pulmonary hypertension (PH). The study, which was published in the Journal of the American Heart Association (JAHA), highlighted the algorithms ability to analyze heart sounds recorded with a digital stethoscope for identifying ele

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Association between pan-immune-inflammation value and coronary heart disease in elderly population: a cross-sectional study

Frontiers in Cardiovascular Medicine

BackgroundSystemic inflammation, immune and nutrition status are closely linked to the occurrence and development of coronary heart disease (CHD). Pan-immune-inflammation value (PIV) is a new method for evaluating systemic inflammation and immune status. Our objective is to explore the connection between PIV and CHD especially in elderly people, as well as the diagnostic value of PIV combined with controlling nutritional status (COUNT) score for CHD.MethodsParticipants eligible for the study wer

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Behavioral Strategies to Conquer Obesity in Clinical Care

Cardiometabolic Health Congress

Obesity is a complex, chronic condition that significantly impacts cardiometabolic health and overall well-being. While management can be challenging, research-backed behavioral strategies are delivering promising results. Healthcare professionals can empower patients to achieve sustainable weight loss through practical lifestyle interventions. #1 Dietary Modifications: Evidence-Based Approaches Low-Fat vs.

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A smartphone-guided secondary prevention digital health application reduces systolic blood pressure in patients with chronic coronary syndrome and insufficient blood pressure control

Frontiers in Cardiovascular Medicine

BackgroundChronic coronary syndrome (CCS) leads to high morbidity and mortality despite therapeutic advances in recent decades. Several modifiable risk factors, including increased blood pressure (BP), significantly contribute to cardiovascular risk in CCS. Therefore, optimal secondary prevention includes managing BP through lifestyle changes and pharmacological therapy.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Discrimination and calibration performances of non-laboratory-based and laboratory-based cardiovascular risk predictions: a systematic review

Open Heart

Background and objective This review compares non-laboratory-based and laboratory-based cardiovascular disease (CVD) risk prediction equations in populations targeted for primary prevention. Design Systematic review. Methods We searched five databases until 12 March 2024 and used prediction study risk of bias assessment tool to assess bias. Data on hazard ratios (HRs), discrimination (paired c-statistics) and calibration were extracted.

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The weight-adjusted-waist index predicts all-cause and cardiovascular mortality in hypertension

Frontiers in Cardiovascular Medicine

BackgroundWeight-adjusted-waist (WWI) is a novel indicator of obesity that reflects the degree of central obesity in the human body.ObjectivesThe study aimed to explore the relationship between WWI and mortality in hypertensive individuals.MethodsCross-sectional data from the 20012018 National Health and Nutrition Examination Survey (NHANES) dataset were used in this study.

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Anatomical characteristics of mitral isthmus and its spatial relationship with the esophagus in patients undergoing atrial fibrillation ablation using CT angiography

Frontiers in Cardiovascular Medicine

BackgroundThis study examines the anatomical characteristics of the mitral isthmus (MI) and its spatial relationship with the esophagus in patients undergoing atrial fibrillation ablation, using cardiovascular computed tomographic angiography (CTA). Understanding this relationship is crucial to minimize the risk of esophageal injuries during ablation procedures.MethodsThe investigation included 300 participants, divided into 200 subjects in the experimental group undergoing atrial fibrillation a

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Higher Levels of 'Good' Cholesterol Linked to Increased Glaucoma Risk

Med Page Today

(MedPage Today) -- Higher levels of high-density lipoprotein cholesterol (HDL-C) were associated with an increased risk of glaucoma, while high levels of low-density lipoprotein cholesterol (LDL-C), total cholesterol, and triglycerides were associated.

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Can Lp(a) become the next A1C? A case for digital health management tools to overcome inertia to Lipoprotein (a) testing

Frontiers in Cardiovascular Medicine

Despite its known correlations with risk of cardiovascular disease, awareness and testing for Lipoprotein (a) lags that of other serological markers with estimates that less than 1% of the US population have undergone screening. Herein we outline how digital tools framed around motivational models (COM-B and SEM), might help increase likelihood of patients seeking Lp(a) testing as part of their managed care.

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Potassium-enriched salt shows promise for cutting recurrent stroke risk in clinical trial

Medical Xpress - Cardiology

Potassium supplements in salt were associated with reduced rates of recurrent stroke and mortality in a large-scale cluster randomized clinical trial involving patients in rural northern China. Findings come from a subgroup (stroke patients) analysis within the original Salt Substitute and Stroke Study (SSaSS), an international study conducted in China.

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Association of neutrophil-to-lymphocyte ratio with severe abdominal aortic calcification: new evidence from the United States

Frontiers in Cardiovascular Medicine

BackgroundAbdominal aortic calcification (AAC), an early indicator of abdominal aortic wall atherosclerosis, is a marker of subclinical atherosclerosis and a predictive factor for vascular-associated morbidity and mortality. These outcomes are driven by inflammatory processes. Given the pivotal role of inflammatory mediators in the pathogenesis of aortic calcification, inflammation has attracted interest as a peripheral biomarker for early mortality prediction in patients with aortic calcificati

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AI proves better than humans at analyzing long-term ECG recordings in large international study

Medical Xpress - Cardiology

In patients with symptoms such as irregular heartbeats, dizziness, or fainting, or in individuals that physicians suspect may have atrial fibrillation, many days of ECGs may be required for diagnosis"long-term ECG recordings." These recordings must then undergo a time-consuming and human resource-intensive review to identify heart rhythm abnormalities.

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When Cardiac Warning Signs Go Unrecognized

Med Page Today

(MedPage Today) -- In November 2023, what should have been a routine dinner outing with my family turned into a tragedy. My 73-year-old father collapsed at our table from a heart attack and died an hour later. His death came just 5 days after an.

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Deep learning to increase accessibility, ease of heart imaging

Science Daily - Heart Disease

Researchers have developed a method that leverages artificial intelligence to ensure accurate heart scans without added radiation or cost.

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Anaphylaxis Following Non-COVID Vaccines Are Rare but Vary by Type

HCPLive

An analysis found anaphylaxis following non-COVID vaccines is rare, with greater rates for yellow fever and influenza vaccines.

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Certain Diabetes Medications May Ease COPD

Med Page Today

(MedPage Today) -- SGLT2 inhibitors and GLP-1 receptor agonists were associated with fewer exacerbations of chronic obstructive pulmonary disease (COPD), according to propensity score-matched cohort studies that emulated randomized clinical trials.

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Factors Such as Smoking, Late Onset Linked to Active HS in Patients Over 50

HCPLive

In this study, investigators highlighted factors associated with active hidradenitis suppurativa over the age of 50 such as smoking, male gender, and later onset of disease.

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Some Contraceptives Carry Higher Venous Thromboembolism Risk Than Others

Med Page Today

(MedPage Today) -- Among hormonal contraceptive users, risk of venous thromboembolism (VTE) varied by method and dose, with combined pills and injections having the highest risk, a Danish nationwide cohort study found. The standardized VTE rates.

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Cardiovascular Hospitalizations Burden the US More than Denmark

HCPLive

Cardiovascular hospitalization rates were higher in the US than in Denmark, driven by a significant increase in heart failure and myocardial infarction hospitalizations.

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Expert explains how to improve heart health, even if your family has history of heart conditions

Medical Xpress - Cardiology

It's not unusual to have one or more family members with some form of heart disease. Nonetheless, some people may not even know they have heart disease until they experience a heart attack or stroke or are diagnosed with heart failure. Despite the prevalence of heart disease, many people are still unclear about how genetics can impact heart disease and, most importantly, what they can do to lower their risk.

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Importance of N2BA Titin in Maintaining Cardiac Homeostasis and Its Role in Dilated Cardiomyopathy

Circulation: Heart Failure

Circulation: Heart Failure, Ahead of Print. BACKGROUND:TTN (titin) is the third myofilament type of the cardiac sarcomere and performs important functions that include generating passive tension. Changes in TTN expression are associated with cardiac dysfunction, and TTN is one of the main genes linked to dilated cardiomyopathy (DCM). DCM is frequently associated with changes in the expression of N2BA (compliant cardiac TTN isoform), 1 of the 2 major TTN isoforms found in the heart (the other iso

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In Food Allergy, Exposure to Store-Bought Peanut Butter Bests Avoidance Strategies

HCPLive

Data from the CAFETERIA trial provide insight into exposure vs avoidance strategies for high-threshold peanut allergy.

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SARS-CoV-2 infection linked to more rapid plaque growth in lesions

Medical Xpress - Cardiology

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with more rapid progression of coronary artery lesion-based plaque volume, according to a study published online Feb. 4 in Radiology.

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FDA Grants Fast Track Designation to Rezpegaldesleukin for Atopic Dermatitis

HCPLive

The drug given this designation, known as rezpegaldesleukin, is indicated for adult and pediatric patients aged 12 years and older with atopic dermatitis.

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7 things to know from the International Stroke Conference

Becker's Hospital Review - Cardiology

Flossing was associated with a 44% lower risk of cardioembolic stroke, a 22% lower risk of ischemic stroke and a 12% lower risk of atrial fibrillation, according to research presented at the American Heart Association's annual International Stroke Conference.

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Clinical Quiz: Diagnosis and Biomarkers in Anaphylaxis

HCPLive

Test your knowledge of the 2023 Anaphylaxis Update from the Joint Task Force on Practice Parameters, focusing on diagnoses and biomarkers!

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Could AI replace heart catheterization? 4 things to know

Becker's Hospital Review - Cardiology

An AI-powered neural network, or deep machine learning model, may be as effective as catheterization at monitoring heart health, according to a study published Jan. 7 in Communications Medicine.

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Nerandomilast Meets Primary Endpoint in Improving FVC in Progressive Pulmonary Fibrosis

HCPLive

Boehringer plans to soon submit a new drug application for nerandomilast for treating PPF to the FDA.

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Right middle lobe torsion after right upper lobectomy despite pneumopexy in an adult: a case report and review of the literature

Journal of Cardiothoracic Surgery

Right middle lobe (RML) torsion is the most common form of lobar torsion. It usually happens after right upper lobe (RUL) lobectomy, especially when pneumopexy is not performed. Although various surgical techn.

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FDA Accepts Lerodalcibep BLA for LDL-C Reduction in High-Risk Patients

HCPLive

Announced by LIB Therapeutics Inc., the agency has set a PDUFA target action date of December 12, 2025.

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Radiomics integration based on intratumoral and peritumoral computed tomography improves the diagnostic efficiency of invasiveness in patients with pure ground-glass nodules: a machine learning, cross-sectional, bicentric study

Journal of Cardiothoracic Surgery

Radiomics has shown promise in the diagnosis and prognosis of lung cancer. Here, we investigated the performance of computed tomography-based radiomic features, extracted from gross tumor volume (GTV), peritum.

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Headache Diagnoses Linked to Increased Suicide Risk

HCPLive

A study found a strong link between headache disorders and suicide risk, including tension-type headaches.

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Dose-Dependent Ventricular Lesion Formation Using a Novel Large-Area Pulsed Field Ablation Catheter: A Preclinical Feasibility Study

HeartRhythm

Pulsed-field ablation (PFA) has shown promising data in terms of safety and procedural efficiency for pulmonary vein isolation (PVI). Large-area focal PFA catheter designs might be suitable to deliver deep and durable lesions in ventricular myocardium.

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eRapa Recieves FDA Fast Track Designation for Familial Adenomatous Polyposis

HCPLive

The Fast Track Designation was granted to Biodexa Pharmaceuticals eRapa based on phase 2 data showing its safety and tolerability in adults with FAP.

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What you need to know about the new implants to patch up failing hearts. Are they really a 'breakthrough'?

Medical Xpress - Cardiology

There are many difficulties in converting any biological research into a medicine that will treat patients. Because of the complexity involved, these difficulties apply especially to translating cell research in the laboratory to a successful treatment for heart failure, where the heart is unable to pump blood around the body properly.

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Copper and Iron Associated With Fibromyalgia Risk

HCPLive

Copper had a positive association with FM risk and iron had a negative association.

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