Stroke: Vascular and Interventional Neurology

AUGUST 16, 2023

Stroke: Vascular and Interventional Neurology, Ahead of Print. Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke that results in painless vision loss attributable to retinal infarction. A keen understanding of clinical presentation and underlying pathophysiological features is key to timely intervention and development of new treatment modalities.

Article 40

Article Thrombolysis Risk Factors Ischemia 40

HeartRhythm

AUGUST 16, 2023

Lying in a hospital bed, waiting to be scheduled for a pacemaker implant, I realized the irony that I would be the recipient of the innovations I was instrumental in initially developing more than 50 years ago.

Innovation 40

Innovation Pacemaker Hospital 40

Stroke: Vascular and Interventional Neurology

AUGUST 16, 2023

Stroke: Vascular and Interventional Neurology, Ahead of Print. Acute stroke management has become increasingly complex, incorporating medical, endovascular, and open surgical treatments that are potentially implemented across multiple hospitals for the same patient. Hospitals work in ever‐expanding networks to provide cost‐effective stroke care, balancing capital and labor costs, expertise, and catchment reach.

Stroke 40

Stroke Strokes Hospital Research 40

HeartRhythm

AUGUST 16, 2023

Ventricular repolarization dispersion derives from heterogeneities in action potential duration (APD) and its associated effective refractory period (ERP) across ventricular walls, between the left and right ventricles, and between the apex and the base of the ventricles.1,2 Enhanced dispersion of repolarization under a variety of pathological conditions may serve as substrates for functional reentry leading to life-threatening polymorphic ventricular tachycardia (VT) or ventricular fibrillation

Tachycardia 40

Tachycardia 40

Open Heart

AUGUST 16, 2023

Objectives Two interlinked surveys were organised by the British Heart Foundation Data Science Centre, which aimed to establish national priorities for cardiovascular imaging research. Methods First a single time point public survey explored their views of cardiovascular imaging research. Subsequently, a three-phase modified Delphi prioritisation exercise was performed by researchers and healthcare professionals.

Cardiovascular Imaging 52

Cardiovascular Imaging Research Quality of Life Exercise 52

Open Heart

AUGUST 16, 2023

Objective To characterise cardiac remodelling, exercise capacity and fibroinflammatory biomarkers in patients with aortic stenosis (AS) with and without diabetes, and assess the impact of diabetes on outcomes. Methods Patients with moderate or severe AS with and without diabetes underwent echocardiography, stress cardiovascular magnetic resonance (CMR), cardiopulmonary exercise testing and plasma biomarker analysis.

Exercise 52

Exercise Diabetes Stenosis Aortic 52

Open Heart

AUGUST 16, 2023

Introduction Systemic low-grade inflammation is a fundamental pathophysiological mechanism of heart failure with preserved left ventricular ejection fraction (HFpEF). The efficacy of anti-inflammatory therapy in HFpEF is largely understudied. The aim of the study is to assess the anti-inflammatory effect of colchicine in HFpEF by looking at inflammatory biomarkers: high-sensitivity C reactive protein (hsCRP) and soluble suppression of tumorigenicity 2 (sST2).

Heart Failure 40

Heart Failure Biomarkers 40