Sun.Nov 10, 2024

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Study Finds Most Children with Hep C have Developmental Disorder, Learning Difficulty

HCPLive

Research presented at NASPGHAN 2024 found most children with chronic hepatitis C had neurodevelopmental disorders, highlighting the need for proactive care.

Research 119
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A tonic for tumultuous times: an interview with “Reasons To Be Cheerful”

Heart Sisters

In this article from "Reasons To Be Cheerful", the Global Alliance for Women’s Health warns that it’s simply too expensive to ignore half of humankind.

Article 75
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Rurality Does Not Account for Disparities in Veteran Care for Rheumatoid Arthritis

HCPLive

Veterans residing in rural areas were only 10% more likely to initiate biologic therapies than those residing in rural areas.

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Elevated glucose levels increase vascular calcification risk by disrupting extracellular pyrophosphate metabolism

Cardiovascular Diabetology

Vascular calcification is a major contributor to cardiovascular disease, especially diabetes, where it exacerbates morbidity and mortality. Although pyrophosphate is a recognized natural inhibitor of vascular.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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NASPGHAN 2024: PEDFIC Data Highlight Safety of Odevixibat in Pediatric Patients with PFIC

HCPLive

PEDFIC data at NASPGHAN 2024 show mild, transient diarrhea events with odevixibat for cholestatic pruritus in PFIC, resolving in most cases.

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La puntuación de riesgo de enfermedades cardíacas del MESA funcionó bien con o sin la raza incluida

American Heart News - Heart News

Puntos destacados de la investigación: Una versión de la puntuación de riesgo de enfermedades cardíacas del Estudio multiétnico de la aterosclerosis (MESA) que no incluía la raza predijo el riesgo de enfermedades cardíacas tan bien como la versión.

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Perceptions About Diversity, Equity, and Inclusion Among Cardiovascular Fellows‐in‐Training

Journal of the American Heart Association

Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024.

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Trends in Risk & Management Strategies for Water Bead Injuries, with Patrick Reeves, MD

HCPLive

A Q&A with a pediatric gastroenterologist on new data detailing trends in water bead injuries in the US from 2013 through 2023.

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Ketone Treatment in Heart Failure With Preserved Ejection Fraction: Recharging the Heart or Reducing Filling Pressures?

Circulation

Circulation, Volume 150, Issue 20 , Page 1584-1587, November 12, 2024.

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Horizontal QRS Axis Predicts Response to Cardiac Resynchronization Therapy in Heart Failure Patients with Left Bundle Branch Block

HeartRhythm

Electrocardiogram criteria for left bundle branch block (LBBB) inadequately predict left ventricular electrical dyssynchrony, complicating cardiac resynchronization therapy (CRT) candidate selection.

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From the Literature

Circulation

Circulation, Volume 150, Issue 20 , Page 1638-1639, November 12, 2024.

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What does a final diagnosis of STEMI vs. NSTEMI depend upon?

Dr. Smith's ECG Blog

Written by Pendell Meyers, few edits by Smith A woman in her 70s was woken from sleep by midsternal chest pain radiating to left arm with nausea. EMS arrived and recorded this ECG: What do you think? Queen of hearts explainability image. Overall High confidence OMI. Smith : this is an "Active OMI". The artery is occluded at this point in time. The ECG shows sinus rhythm, normal QRS, and signs of inferoposterolateral OMI.

STEMI 82
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Letter by Xu et al Regarding Article, “Postprocedural Anticoagulation After Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction: A Multicenter, Randomized, Double-Blind Trial”

Circulation

Circulation, Volume 150, Issue 20 , Page e444-e444, November 12, 2024.

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The serum uric acid/high-density lipoprotein cholesterol ratio: a novel predictor for the presence of abdominal aortic aneurysm

Frontiers in Cardiovascular Medicine

ObjectiveRobust evidence has demonstrated that inflammation plays an important role in the occurrence and development of abdominal aortic aneurysms (AAA). The serum uric acid (UA)/high-density lipoprotein cholesterol (HDL-C) ratio (UHR) has recently been recognized as a new biomarker for evaluating inflammatory and anti-inflammatory interactions. However, whether UHR is associated with AAA remains unclear.

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Cardiac Resynchronization Therapy: New Perspectives

Circulation

Circulation, Volume 150, Issue 20 , Page 1563-1566, November 12, 2024.

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Rates of and Indications for Subcutaneous ICD Extraction: A Multihospital Healthcare System Analysis

Journal of Cardiovascular Electrophysiology

ABSTRACT Introduction The subcutaneous implantable cardioverter defibrillator (S-ICD) is an alternative to a transvenous ICD in patients who meet the criteria for ICD implantation without concurrent need for cardiac pacing. The objective of this study is to examine the rates of and indications for S-ICD removal and extraction. Methods A retrospective analysis of all patients who underwent S-ICD implantation between 2010 and 2022 at a single multihospital healthcare system was performed.

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Identifying Atypical Interatrial Block

Circulation

Circulation, Volume 150, Issue 20 , Page 1645-1647, November 12, 2024.

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Catheter ablation of atrial fibrillation in women with heart failure with preserved ejection fraction

Frontiers in Cardiovascular Medicine

BackgroundHeart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) often coincide. Female sex is associated with both increased prevalence of HFpEF and reduced therapeutic efficacy of catheter ablation of AF. This sub-analysis of the previously published AFFECT-study evaluates outcome after cryoballoon-ablation in women with and without HFpEF.MethodsOne-hundred-and-two patients (LVEF ≥ 50%) scheduled for cryoballoon-ablation of AF were prospectively enrolled.