Tue.May 14, 2024

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Artificial intelligence tool to improve heart failure care

Science Daily - Heart Disease

The powerful new AI tool can predict heart failure outcomes in specific patients, helping doctors improve care.

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New Treatment in Pipeline for Patients with Hypertrophic Cardiomyopathy

DAIC

Getty Images milla1cf Tue, 05/14/2024 - 13:00 May 14, 2024 — One of the most common genetic heart diseases worldwide, hypertrophic cardiomyopathy (HCM) causes the walls of the left ventricle to become thick and stiff. In about 70 percent of cases, patients with HCM experience obstruction to blood flow, which increases pressures in the heart and can lead to chest pain, shortness of breath and reduced exercise capacity.

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Tildrakizumab Effective for Patients with Psoriasis Unresponsive to Anti-IL17

HCPLive

A study showed tildrakizumab treated difficult-to-treat psoriasis areas in patients who failed anti-IL17 treatment.

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GE HealthCare and Medis Medical Imaging Announce Collaboration Focused on Non-Invasive Coronary Assessments to Help Advance Precision Care in Treatment of Coronary Artery Disease

DAIC

milla1cf Tue, 05/14/2024 - 12:53 May 14, 2024 — GE HealthCare , a leading global medical technology, pharmaceutical diagnostics and digital solutions innovator, and Medis Medical Imaging , a leading cardiac imaging software company, announced their collaboration aimed at helping advance precision care in the diagnosis and treatment of coronary artery disease ( CAD ).

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Hidradenitits Suppurativa Linked to Increased Risk of Cardiovascular Diseases

HCPLive

Patients with hidradenitis suppurativa had the greatest risk of developing various CVS, with heart failure being the most common one.

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Early diagnosis & treatment of peripheral artery disease essential to improve outcomes, reduce amputation risk

American Heart News - Heart News

Guideline Highlights: The new joint guideline from the American Heart Association and the American College of Cardiology provides recommendations to guide clinicians in the treatment of patients with lower extremity peripheral artery disease (PAD) and.

More Trending

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SHINE Trial Sheds Light on Deadly Stroke Complication

DAIC

UVA Health's Karen Johnston, MD, the SHINE trial leader, was pleased to see the new insights into best practices for stroke care. “These data from the SHINE trial continue to inform the national stroke community about potential approaches to treating hyperglycemic stroke patients to assure better outcomes,” she said. Dan Addison | UVA Communications milla1cf Tue, 05/14/2024 - 12:57 May 14, 2024 — An ambitious, nationwide clinical trial led by UVA Health ’s Karen Johnston , MD, has provided docto

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Therapeutic strategies targeting mechanisms of macrophages in diabetic heart disease

Cardiovascular Diabetology

Diabetic heart disease (DHD) is a serious complication in patients with diabetes. Despite numerous studies on the pathogenic mechanisms and therapeutic targets of DHD, effective means of prevention and treatme.

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Physical Activity and Progression of Coronary Artery Calcification

JAMA Cardiology

This cohort study examines data for men and women 40 years and older to determine the association between high-volume leisure-time aerobic physical activity and the progression of coronary artery calcium over time.

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Have a heart – caregivers need care, too

American Heart News - Heart News

DALLAS, May 14, 2024 — Living with a chronic medical condition after surviving a heart attack or stroke may come with additional health and personal care needs. Often survivors must rely on a family member or close friend to help. However, there’s a.

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UPMC Harrisburg 1st to use new TAVR system

Becker's Hospital Review - Cardiology

UPMC Harrisburg pioneers new transcatheter aortic valve replacement system, providing improved lifetime management for patients with aortic valve stenosis.

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Osteosarcopenia and Mortality in Older Adults Undergoing Transcatheter Aortic Valve Replacement

JAMA Cardiology

This cohort study examines whether there is an association between osteosarcopenia and adverse outcomes, such as increased risk of mortality, in older adults following transcatheter aortic valve replacement (TAVR).

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Efferocytosis in atherosclerosis

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 15 May 2024; doi:10.1038/s41569-024-01037-7 In this Review, Adkar and Leeper describe the mechanisms of programmed cell death and efferocytosis, discuss how efferocytosis becomes impaired in atherosclerosis and other cardiometabolic diseases, and suggest potential strategies to target these pathways for the treatment of atherosclerotic cardiovascular disease.

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Antihypertensive Medication Initiation and Fracture Risk in Nursing Home Residents

NEJM Journal Watch - Cardiology

Within 30 days of antihypertensive medication initiation, the rate of fracture was more than twice as high in initiators than in noninitiators.

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FDA Issues CRL for HEPLISAV-B in Adults on Hemodialysis

HCPLive

The CRL for the sBLA cites a lack of sufficient data to support the full evaluation of the effectiveness and safety of a 4-dose regimen in this patient population.

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El diagnóstico y tratamiento tempranos de la enfermedad arterial periférica son esenciales para mejorar los resultados y reducir el riesgo de amputación

American Heart News - Heart News

Aspectos destacados de la guía: La nueva guía conjunta de la American Heart Association (la Asociación Americana del Corazón) y el American College of Cardiology ofrece recomendaciones para guiar a los médicos en el tratamiento de pacientes con.

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Age, Genetics Help Predict Proliferative Sickle Cell Retinopathy

HCPLive

Age and sickle cell disease genotype predicted individuals with sickle cell retinopathy at risk for proliferative disease.

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Florida hospital establishes electrophysiology program after $10M donation

Becker's Hospital Review - Cardiology

Jupiter (Fla.) Medical Center established the Elliot Family Center for Cardiac Electrophysiology thanks to a $10 million donation, CBS12 reported May 13.

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FDA Extends Review for TransCon PTH in Hypoparathyroidism to August 2024

HCPLive

The FDA has extended the review period for palopegteriparatide in treatment of hyperparathyroidism in adult patients by 3 months to August 14, 2024.

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Tenga corazón: los cuidadores también necesitan de cuidados

American Heart News - Heart News

DALLAS, 14 de mayo de 2024 — Vivir con una afección médica crónica luego de sobrevivir a un ataque cardíaco o derrame cerebral puede acarrear muchas otras necesidades de cuidado personal y de salud, y con frecuencia los supervivientes deben recurrir a la.

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HCV Tops HBV as Leading Cause of Cirrhosis, Global Burden Projected to Increase

HCPLive

Study results highlight the role of HCV and alcohol use in the growing global disease burden posed by cirrhosis, which is projected to increase over the next 20 years.

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Association between the triglyceride-glucose index and in-hospital major adverse cardiovascular events in patients with acute coronary syndrome: results from the Improving Care for Cardiovascular Disease in China (CCC)-Acute Coronary Syndrome project

Cardiovascular Diabetology

Although the TyG index is a reliable predictor of insulin resistance (IR) and cardiovascular disease, its effectiveness in predicting major adverse cardiac events in hospitalized acute coronary syndrome (ACS).

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Elevated Lp(a) Can Predict Premature ASCVD Risk

HCPLive

A systematic review and meta-analysis of 51 studies suggests elevated Lp(a) can help predict risk of premature atherosclerotic cardiovascular disease.

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Non-neuronal cell-derived acetylcholine, a key modulator of the vascular endothelial function in health and disease

Frontiers in Cardiovascular Medicine

Vascular endothelial cells play an important role in regulating peripheral circulation by modulating arterial tone in the microvasculature. Elevated intracellular Ca2+ levels are required in endothelial cells to induce smooth muscle relaxation via endothelium-dependent mechanisms such as nitric oxide production, prostacyclin, and endothelial cell hyperpolarization.

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Anti-IL-17A Biologics Superior in Treating Patients with Psoriasis, Concomitant Nail Psoriasis

HCPLive

These results may support clinical decision-making for psoriasis and nail psoriasis management and may allow future real-world studies to further understand the nature of this skin disease.

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Interacting and joint effects of triglyceride-glucose index and hypertension on stroke risk in middle-aged and older Chinese adults: a population-based prospective cohort study

Frontiers in Cardiovascular Medicine

BackgroundTriglyceride-glucose (TyG) index and hypertension were well-established risk factors for stroke. And TyG index was associated with hypertension. However, no prior study has investigated the interactive effects of the TyG index and hypertension on stroke. This study examined whether hypertension mediates associations of TyG index with incident stroke and the extent of interaction or joint relations of TyG index and hypertension with stroke in middle-aged and older Chinese adults.Methods

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Anti-VEGF Improves Outcomes in Proliferative Sickle Cell Retinopathy

HCPLive

Within one month of treatment, anti-VEGF therapy improves anatomic and visual outcomes among eyes with stage 3 and 4 proliferative sickle cell retinopathy.

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Stacking Invasive Tests for Chronic Coronary Syndrome: Good Results, Less Hassle

Med Page Today

(MedPage Today) -- PARIS -- Using a structured series of tests together, operators greatly improved the diagnostic accuracy of invasive coronary angiography (ICA) for people with chronic coronary syndrome (CCS), the prospective AID-ANGIO study.

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Sparsentan Limits eGFR Reduction Regardless of IgAN Patient Proteinuria Levels

HCPLive

Further analyses into the 2-year PROTECT trial further support the longevity of benefit with sparsentan in patients with IgAN.

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Joined Cath Procedures Turn the Table on SAVR-CABG

Med Page Today

(MedPage Today) -- PARIS -- For patients with severe aortic stenosis (AS) and concomitant obstructive coronary artery disease (CAD), a percutaneous combined intervention worked surprisingly well relative to surgery, the TCW randomized trial found.

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Andrew Alexis, MD, MPH: Findings on Trifarotene for Acne Sequelae in Skin of Color

HCPLive

This interview featured a discussion of Alexis’s team’s findings on the importance of treating patients with skin of color and acne-induced post-inflammatory hyperpigmentation.

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Improved Clinical Outcomes with Intravascular Imaging-Guided PCI: Impact of Standardized Optimization Protocols

Cardiology Update

Intravascular imaging (IVI), such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT), play a crucial role in assessing lesion characteristics and optimizing stent placement during percutaneous coronary intervention (PCI). Studies have consistently shown that procedural optimization guided by IVUS leads to better clinical outcomes compared to angiography-guided PCI alone.

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1 in 12 Lupus Neprhitis Patients Experience Cardiovascular Events

HCPLive

Data presented at NKF Spring Clinical Meeting suggest events including myocardial infarction and stroke are more prevalent among patients with lupus in North America.

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Durable Antithrombotic Therapy After Acute Coronary Syndromes: Less Is More

NEJM Journal Watch - Cardiology

A clinical trial in China suggests better outcomes with long-term clopidogrel monotherapy than DAPT.

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Transmasculine Hormone Therapy Could Carry Greater Cardiovascular Risk than Transfeminizing Therapy

HCPLive

Transmasculine patients undergoing GAHT may experience adverse lipid profile changes, unlike transfeminine counterparts, which investigators say is cause for closer monitoring.

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Regarding Immune Mechanisms Driving Hypertension in REGARDS

Hypertension Journal

Hypertension, Volume 81, Issue 6 , Page 1254-1256, June 1, 2024.