Thu.Sep 26, 2024

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Estimated Long-Term Benefits of Finerenone in Heart Failure

JAMA Cardiology

This prespecified analysis of the Finerenone Trial to Investigate the Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) randomized clinical trial investigates the long-term effects of treatment with the nonsteroidal mineralocorticoid receptor antagonist, finerenone, in patients with heart failure with mildly reduced or preserved ejection fraction.

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DAA Marketing Payments From Manufacturers Linked to Physician Prescribing Patterns

HCPLive

Physicians who received pharmaceutical industry payments related to 4 different direct-acting antivirals were more likely to prescribe these medications.

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Timely Skin Cancer Screening After Organ Transplant Still Lacking

Med Page Today

(MedPage Today) -- Recent skin cancer risk stratification guidelines did not improve rates of timely dermatologic follow-up visits among solid organ transplant recipients, according to an analysis of claims data. The rate of post-transplant dermatology.

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Absolute, Functional Iron Deficiency Affects Large Proportion of US Adults

HCPLive

Rates of absolute and functional iron deficiency were high among adults in the US, even in those without anemia, heart failure, or chronic kidney disease.

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GLP-1 Agent May Hold Opioid Use Disorder Benefit

Med Page Today

(MedPage Today) -- Semaglutide (Ozempic, Wegovy) may help reduce the risk of an opioid overdose in certain people, an emulation target trial suggested. Over a 1-year follow-up, people with comorbid type 2 diabetes and opioid use disorder (OUD.

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Study Reveals Factors Associated with Non-DKD on Kidney Biopsy in Patients with Diabetes

HCPLive

Lack of retinopathy, lower hemoglobin A1c levels, preserved eGFR, microalbuminuria, and lower UPCR were linked to non-DKD.

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Advancing TAVI Expertise: A Comprehensive Training at Adana City Health Center

ADN Center of Excellence

In our ongoing commitment to advancing cardiovascular care, ADN CoE recently hosted an intensive Transcatheter Aortic Valve Implantation (TAVI) Training at the prestigious Adana City Health Training and Research Center. This event, led by the renowned Prof. Dr. Halil Ibrahim Kurt, offered an unparalleled opportunity for cardiologists to enhance their skills in this cutting-edge procedure.

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The heart guideline lowering hospital burden, mortality

Becker's Hospital Review - Cardiology

Hospitals with higher guideline-directed medical therapy scores showed lower rates of mortality, rehospitalization and costs in heart failure patients, according to a Sept. 25 study released by JAMA Cardiology.

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FDA Approves Xanomeline and Trospium Chloride (Cobenfy) for Schizophrenia

HCPLive

The FDA approves Cobenfy, the first pharmacological approach to treating schizophrenia since the 1970s.

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Semaglutide and Diuretic Use in HFpEF With Obesity

American College of Cardiology

Does semaglutide efficacy vary with baseline diuretic use and does semaglutide change diuretic dose in patients with heart failure with preserved ejection fraction (HFpEF)?

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Temtokibart Proves Comparable to Dupilumab for Atopic Dermatitis in Phase 2a Trial

HCPLive

Temtokibart showed similar efficacy to dupilumab in treating moderate-to-severe atopic dermatitis, with faster skin hydration improvements in a phase 2a trial.

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The link between high blood pressure and aortic aneurysms

CTVS

An aortic aneurysm is a very serious condition that occurs when the aorta (the largest artery in the body that comes off the heart) develops a bulb-like formation. If the aneurysm is not treated appropriately, it can rupture or lead to an aortic dissection, causing blood to dangerously leak out of the aorta and prove life-threatening.

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Elliott Elias, MD, MPH: Overcoming Challenges in Prosthetic Valve Evaluation

HCPLive

Elias discusses the challenges of prosthetic valve evaluation, highlighting the role of sonographers, Doppler imaging, and the importance of ongoing training.

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Risk of Stroke and Incident Atrial Fibrillation in Patients in Sinus Rhythm With Non-Ischemic Dilated Cardiomyopathy

The American Journal of Cardiology

Publication date: Available online 26 September 2024 Source: The American Journal of Cardiology Author(s): Eduard Ródenas-Alesina, Jordi Lozano-Torres, Pablo Eduardo Tobías-Castillo, Clara Badia-Molins, Maria Calvo-Barceló, Rosa Vila-Olives, Guillem Casas-Masnou, Aleix Olivella San Emeterio, Toni Soriano-Colomé, Rubén Fernández-Galera, Ana B Méndez-Fernández, José A Barrabés, José Rodríguez-Palomares, Ignacio Ferreira-González

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Safety and Efficacy of Janus Kinase Inhibitors

HCPLive

Panelists discuss how the findings from the ORAL Surveillance study regarding cardiovascular and cancer risks associated with tofacitinib have influenced perceptions of JAK inhibitors, emphasizing the need to balance safety concerns with their efficacy in managing rheumatoid arthritis.

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Patiromer HF Medication Optimization for Hyperkalemia

American College of Cardiology

In this prespecified analysis of the DIAMOND trial, what is the effect of patiromer in patients with heart failure with reduced ejection fraction (HFrEF) when examining the current and past hyperkalemia subgroups?

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Closing Remarks

HCPLive

Panelists discuss how their approaches to treating patients with rheumatoid arthritis focus on personalized strategies that prioritize achieving remission while carefully monitoring safety and efficacy outcomes.

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Micro-Nanoplastic Accumulation May Adversely Affect CV Health

American College of Cardiology

The accumulation of micro-nanoplastics (MNPs) in the body may lead to adverse cardiovascular effects and may represent a novel risk factor for cardiovascular disease, according to a state-of-the-art review published in the European Heart Journal.

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ULT Therapy Adherence High for Gout, Nonadherence Increases Flares

HCPLive

Younger people and people without European origin were less likely to adhere to urate-lowering therapy.

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Worldwide CTEPH Registry Long-Term Outcomes

American College of Cardiology

What are the effects of the current therapeutic options for chronic thromboembolic pulmonary hypertension (CTEPH) in a worldwide context?

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Positive Long Term Findings on Nemolizumab Observed for Atopic Dermatitis, Prurigo Nodularis

HCPLive

These new data on treatment of atopic dermatitis and prurigo nodularis were presented by Galderma at the European Academy of Dermatology & Venereology Congress.

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Changes in epicardial adipose tissue volume before and after cryoballoon ablation in patients with atrial fibrillation: supporting the “AF begets EAT” theory

HeartRhythm

Epicardial adipose tissue (EAT) is closely associated with atrial fibrillation (AF), suggesting it may be one of the causes of AF progression. However, it is unclear whether atrial fibrillation affects EAT.

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Delgocitinib Superior to Oral Alitretinoin in Efficacy Findings for Chronic Hand Eczema

HCPLive

The DELTA trial results on delgocitinib cream as a topical option for CHE were presented at the EADV Congress 2024.

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The positive F wave in lead V1 of typical atrial flutter is caused by activation of the right atrial appendage: Insight from mapping during entrainment from the right atrial appendage

Journal of Cardiovascular Electrophysiology

The positive F wave in lead V1 changed during entrainment from the right atrial appendage (RAA) during typical atrial flutter (AFL). The 3-dimensional (3D) electroanatomical map during entrainment from the RAA revealed an area of antidromic capture around the RAA, which was the only difference from the 3D electroanatomical map of typical AFL, proving that the activation around the RAA is responsible for the generation of the positive F wave in lead V1 of typical AFL.

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Responding to FDA Approval of Lebrikizumab for Atopic Dermatitis, with Andrew Alexis, MD, MPH

HCPLive

This interview with Alexis features his reaction to the approval of lebrikizumab for eczema and its significance.

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SAHELI: Do Culturally Adapted Lifestyle Intervention Improve CVD Risk Factors?

American College of Cardiology

A culturally adapted group-based lifestyle intervention targeted towards South Asian participants did not lead to a substantial difference in improving risk factors at one year compared with written health education materials.

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Left Ventricular Hypertrophy Regression Following Transcatheter Aortic Replacement: A Comparison of Self-Expanding Versus Balloon-Expandable Prostheses

The American Journal of Cardiology

Publication date: Available online 25 September 2024 Source: The American Journal of Cardiology Author(s): Talhat Azemi, Fahad Ahmed, Immad Sadiq, William Lane Duvall, Sean McMahon, Jeff F. Mather, Sabet W. Hashim, Raymond G.

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Gefarnate Could Help Reduce Triglycerides in Statin-Treated Adults

HCPLive

A randomized trial suggests gefarnate significantly reduces triglycerides and LDL-C in older adults on statins with residual hypertriglyceridemia.

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Hot Cross Bun Sign After Cerebellar Stroke

Stroke Journal

Stroke, Ahead of Print.

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Pulsed Field Ablation: The Temptation for More While Keeping It Safe

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print.