Thu.Nov 14, 2024

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Cholesterol may not be the only lipid involved in trans fat-driven cardiovascular disease

Medical Xpress - Cardiology

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary and exercise regimens.

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Prehospital Cath Lab Activation. What happened when the medics and patient arrived at this Academic ED?

Dr. Smith's ECG Blog

This was texted to me by a paramedic while I was out running one day: "54 yo male chest pain started at 1pm. History of diabetes type II and stent placement in 2018. I’m seeing hyperacute T waves III, aVF, down sloping depression I and aVL. Thoughts?" What do you think? I responded: "Definite inferior OMI. And Right Ventricular. Activated the Cath Lab.

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Protein in soy may reduce the risk of heart failure by affecting gut bacteria

Medical Xpress - Cardiology

A research team from the Nagoya University Graduate School of Medicine has discovered a promising way to slow the progression of heart failure in mice. They fed mice a diet rich in the soybean protein, β-conglycinin (β-CG), which can support heart health by influencing gut bacteria. Their analysis revealed that the soybean protein rich diet increased the production of the short-chain fatty acids (SCFAs) in the intestine that play a role in protecting the heart.

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Hospitals with highest, lowest readmission rates for coronary bypass

Becker's Hospital Review - Cardiology

Tyler, Texas-based Christus Mother Frances Hospital had the lowest unplanned readmission rate for coronary artery bypass graft surgery in the U.S. between July 1, 2020, and July 30, 2023, according to CMS data released Oct. 30.

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Kara Margolis, MD: Long-Term Impact of Maternal Microbiota on Infant Gut-Brain Health

HCPLive

At NASPGHAN, HCPLive spoke with Margolis about her team’s study on the link between maternal SSRI exposure and an infant’s development of gut-brain interaction disorders.

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5 Most-Cited Takeaways From the 19th Annual Cardiometabolic Health Congress (CMHC) 

Cardiometabolic Health Congress

With the holiday season approaching and fall in full swing, it’s the perfect time to reaffirm our commitment to delivering excellent care, improving patient outcomes, and making the most of every available resource. What better way to join the fall festivities than by spotlighting key insights in cardiorenal metabolic medicine, primary prevention, and quality of life improvements shared at this year’s biggest U.S. cardiometabolic health CME/CE conference: the 19th Annual CMHC.

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Genetic study links heart shape to cardiovascular disease

Medical Xpress - Cardiology

A new, multinational study has revealed that the shape of the human heart, influenced by genetic factors, could serve as a valuable predictor for cardiovascular disease risk.

More Trending

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Study reveals COVID-19 vaccine safety in patients with atrial fibrillation/flutter

Medical Xpress - Cardiology

Development of the coronavirus disease 2019 (COVID-19) vaccine has been key to countering the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite the current endemic status of COVID-19, patients with comorbidities and older adults remain vulnerable to severe illness and death due to COVID-19 infection. Therefore, medical agencies and organizations worldwide recommend COVID-19 vaccination, especially for individuals with an underlying disease.

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Breaking every hour of sedentary time with 10 mins of light exercise significantly reduced blood pressure

Science Daily - Heart Disease

Time spent sedentary beyond six hours per day during growth from childhood through young adulthood may cause an excess increase of 4 mmHg in systolic blood pressure, a new study shows. Continuously engaging in light physical activity (LPA) significantly mitigated the rise in blood pressure.

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Heart rate variability not a reliable marker of aggression

Medical Xpress - Cardiology

New research from the University of St Andrews debunks the theory that Heart Rate Variability (HRV) is linked to aggressive behavior.

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New research shows relationship between heart shape and risk of cardiovascular disease

Science Daily - Heart Disease

A new study has revealed that the shape of the heart is influenced in part by genetics and may help predict the risk of cardiovascular diseases.

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Breaking every hour of sedentary time with ten minutes of light exercise can significantly reduces blood pressure

Medical Xpress - Cardiology

Time spent sedentary beyond six hours per day during growth from childhood through young adulthood may cause an excess increase of 4 mmHg in systolic blood pressure, a new study shows. Continuously engaging in light physical activity (LPA) significantly mitigated the rise in blood pressure.

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Hallucinogen-Related ER Visit Linked to Increased Schizophrenia Risk

HCPLive

A study found a 3.5-fold increased schizophrenia risk in those with hallucinogen-related emergency department visits.

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Echocardiographic Compared With CMR Evaluation of AR

American College of Cardiology

What is the accuracy of the American Society of Echocardiography (ASE) aortic regurgitation (AR) guidelines against cardiac magnetic resonance (CMR)?

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Diabetes Dialogue: Latest Updates on Semaglutide

HCPLive

In this episode, hosts discuss the latest developments in GLP-1 receptor agonists, with a particular focus on semaglutide.

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Fellowship Programs Demystified: Why and When You Should Consider a Fellowship

ADN Center of Excellence

For medical professionals, the path to excellence is one of continuous learning and skill enhancement. Fellowships represent a vital opportunity to bridge the gap between general practice and advanced specialization. Whether you are at the crossroads of choosing your career focus or seeking to refine your expertise, a fellowship could be the game-changing step you need.

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Protein in soy may reduce the risk of heart failure by affecting gut bacteria

Science Daily - Heart Disease

Researchers have found a potential method to slow heart failure progression. They fed mice a diet high in soybean protein, which influenced gut bacteria and supported heart health. Analysis showed that this diet increased the production of the short-chain fatty acids in the gut that help to protect the heart.

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Diabetes Dialogue: Tirzepatide’s Long-Term Obesity Data

HCPLive

In this episode, hosts explore the most recent updates surrounding GLP-1 receptor agonists, including GLP-1 shortages and long-term data on tirzepatide.

Obesity 59
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Machine learning for predicting in-hospital mortality in elderly patients with heart failure combined with hypertension: a multicenter retrospective study

Cardiovascular Diabetology

Heart failure combined with hypertension is a major contributor for elderly patients (≥ 65 years) to in-hospital mortality. However, there are very few models to predict in-hospital mortality in such elderly p.

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Trials and tribulations of cell therapy for heart failure: an update on ongoing trials

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 15 November 2024; doi:10.1038/s41569-024-01098-8 Cell therapy has emerged in the past 20 years as a promising avenue for cardiac repair and regeneration. In this Review, Zhang and colleagues provide an overview of the evolution of cell-based and cell product-based therapies for the treatment of heart failure, including challenges and lessons learned, and summarize ongoing clinical trials on the feasibility of novel or underexplored treatment protocols

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Updated evidence on cardiovascular and renal effects of GLP-1 receptor agonists and combination therapy with SGLT2 inhibitors and finerenone: a narrative review and perspectives

Cardiovascular Diabetology

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have a reliable hypoglycaemic and weight-loss effect that can intervene in obesity, which is the basis of type 2 diabetes pathology. GLP-1RA therapy has sho.

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Updated first aid guidelines enhance care for opioid overdose, bleeding, other emergencies

Medical Xpress - Cardiology

The American Heart Association and the American Red Cross have released the "2024 Guidelines for First Aid," which provide critical updates that equip first aid responders with the latest evidence-based practices to effectively respond to mild, moderate and life-threatening emergencies. The guidelines are published in Circulation.

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ATRIAL TACHYCARDIA WITH PARTLY ABERRANT CONDUCTION

ECG Guru

This ECG comes from Germany, where unfortunately recording is still often done at 50 mm/s. Nevertheless, I believe that you can easily recognize the important changes in this ECG, even if you are not familiar with this recording format. The first two beats are the limb leads, the other beats are the precordial leads.

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Functional block in the initiation and maintenance of common flutter: detailed electrophysiological study and electro-anatomical mapping

Frontiers in Cardiovascular Medicine

IntroductionThe precise pathophysiology of common atrial flutter remains imperfectly known. The mechanisms of arrhythmia initiation and the role of areas of slow conducting myocardium and functional block are still debated topics.MethodsWe conducted a detailed electrophysiological study of a patient to illustrate and refine these concepts. Prior to CTI ablation, electrophysiological study and electro-anatomical mapping were performed, focusing on initiation and maintenance mechanisms of the arrh

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NON CONDUCTED PAC

ECG Guru

Especially in the social media, one sees again and again similar EKGS like the one shown here with the question: What type of AV block is present here? 2nd degree AVB block type I (Wenckebach) or type II (Mobitz)? It is neither one nor the other! Here, a PAC can be seen under the blue arrow, which is not conduced because the AV node is still refractory (the refractory period of the AV node depends on the preceding heart rate).

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The effectiveness of liver transplantation in reducing lipid levels in Saudi children with homozygous familial hypercholesterolemia

Frontiers in Cardiovascular Medicine

IntroductionThe lipid profiles of patients aged <15 years who have been diagnosed with homozygous familial hypercholesterolemia (HoFH) at King Faisal Specialist Hospital & Research Center (Riyadh) were examined.MethodsThe total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels of 17 patients were measured on initial presentation and compared with the levels measured after pharmacological treatment and then again after liver transplantation.ResultsAt the end of the pharmacolo

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Association of prior tuberculosis with cardiovascular status in perinatally HIV-1-infected adolescents

Open Heart

Background Whether, and how, co-occurring HIV-1 infection (HIV) and tuberculosis (TB) impact cardiovascular status, especially in adolescents with perinatally acquired HIV (APHIV), have not been examined. We hypothesised that APHIV with previous TB disease have worse cardiac efficiency than APHIV without TB, which is mediated by increased inflammation and disordered cardiometabolism.

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CO-CREATION-HF protocol: clinical trial to evaluate the impact of a comprehensive and hybrid cardiac rehabilitation model on patients with heart failure

Frontiers in Cardiovascular Medicine

IntroductionComprehensive, hybrid cardiac rehabilitation (CR) models have been scantly investigated in heart failure (HF) populations, particularly in low-resource settings. CO-CREATION-HF aims to evaluate the effectiveness of such a model compared to supervised exercise alone.Methods and analysisA 2 parallel-arm, multi-center randomized clinical superiority trial will be conducted with blinded outcome assessment. 152 HF patients (NYHA class II or III) will be recruited consecutively, and random

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First Fungal Spore Calendar Developed for Patients with Asthma, Allergies

HCPLive

A new analysis highlights the seasonal patterns of airborne fungal spores that can be found in the central region of England, with a calendar developed to this same end.

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Case Report: A rare diffuse mitral valvular myxoma

Frontiers in Cardiovascular Medicine

Cardiac myxoma is a common benign tumor, however, myxoma extensively distributed on the mitral valve is rare and seldom reported. A patient who presented with exertional dyspnea and chest tightness was examined by transthoracic and transesophageal echocardiography successively. Multiple neoplasms on the mitral valve with moderate mitral regurgitation were found and were further proved to be a diffuse myxoma on the mitral valve by histology.

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Maternal TDF Therapy, Infant Vaccination Prevents Mother-to-Child HBV Transmission

HCPLive

In areas where HBV immune globulin is not available, maternal TDF therapy at week 16 and infant HBV vaccination can prevent mother-to-child transmission.

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Association between periodontal disease and atherosclerosis: a bibliometric analysis

Frontiers in Cardiovascular Medicine

BackgroundIn recent years, the relationship between periodontal disease (PD) and atherosclerosis (AS) has garnered significant scholarly attention. Chronic inflammation induced by PD may promote the onset and progression of AS through multiple mechanisms. Given the increasing global incidence of both PD and AS, which adversely affects patients’ quality of life and longevity, further investigation into the interplay between PD and AS is of substantial clinical importance.

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The APAC Recap: Lifestyle Medicine at CAPP Live 2024 with Laura Ross, PA-C

HCPLive

Laura Ross, PA-C, shares insights from the inaugural CAPP meeting on how lifestyle medicine and targeted therapies are transforming cardiovascular care.

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Primary transcatheter dilation of the pulmonary valve in cyanotic patients with tetralogy of Fallot and dominant pulmonary valve stenosis

Frontiers in Cardiovascular Medicine

ObjectivesThis study reviews the outcome of pulmonary valve dilation (PVB) in patients with tetralogy of Fallot (TOF) and predominantly pulmonary valve stenosis as first palliation and the impact of balloon-related cusp tears (BRCTs) on the surgical strategy.BackgroundThe early management of cyanotic patients TOF is still controversial.MethodsThis was a retrospective study of 19 patients with TOF who underwent PVB over 4 years.

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Donations continue for $265M heart institute

Becker's Hospital Review - Cardiology

"NCH Healthcare System receives $5 million donation for $265 million heart institute set to open in 2027. Help reach $72 million fundraising goal.

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Metabolomic profiling of infants undergoing cardiopulmonary bypass and association with clinical outcomes: a systematic review

Frontiers in Cardiovascular Medicine

IntroductionThe incidence of adverse short-term outcomes for infants who undergo complex congenital heart disease (CHD) surgery with cardiopulmonary bypass (CPB) is still high. Early identification and treatment of high-risk patients remain challenging, especially because clinical risk factors often fail to explain the different outcomes of this vulnerable population.

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These are the three big factors driving strokes, experts warn

Medical Xpress - Cardiology

A trio of risk factors not only increase your risk of stroke, but they also raise the odds that such a stroke will be debilitating, a new study warns.

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