Thu.Oct 31, 2024

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Cardiac Arrest Drug Administration Route a Toss Up

Med Page Today

(MedPage Today) -- Intraosseous vascular access for the administration of epinephrine during out-of-hospital cardiac arrest wasn't better than going for the veins first, two separate randomized trials showed. In the PARAMEDIC-3 trial conducted.

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Long COVID inflammation damages the heart, study finds

Science Daily - Heart Disease

New research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.

Research 128
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Exploring the Interplay Between Chronic Kidney Disease and Cardiovascular Disease

HCPLive

In this first of this 5-part series, Lerma and Lala-Trindade discuss the interplay between chronic kidney disease and cardiovascular disease.

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Long COVID inflammation damages the heart, blood analysis finds

Medical Xpress - Cardiology

University of Queensland-led research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.

Research 110
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Stress Triggers IBS Symptoms, Impacts Quality of Life More Than Diet, Study Finds

HCPLive

Mohammad Abuassi, MD, explains how classifying IBS based on triggers can aid the development of effective, personalized approaches to management.

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Can you treat Non-STEMI with thrombolytics if it is OMI (Occlusion MI)? Of course!

Dr. Smith's ECG Blog

This case was sent by an old residency friend, Kirk Lufkin. He works in a small hospital in Northern Michigan. Case A 61 year old female. hypertension no other past history presented with 30 minutes of fluctuating non-radiating heaviness in chest, with diaphoresis and nausea. VS normal. No cardiac past history. Here is her ECG: What do you think? There are inferior hyperacute T-waves (diagnostic of inferior OMI), with 1) reciprocal ST depression in aVL, 2) a reciprocally inverted hyperacute T-wa

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Exploring the Cardiovascular Benefits, Potential of Finerenone

HCPLive

In the final part of this 5-part series, Lala-Trindade discusses the findings of the FINEARTS-HF trial and how it might inform use of finerenone.

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Looking Deeper into Genetic Variants of FSGS, with Jennifer Lai Yee, MD, PhD, MPH

HCPLive

Yee discussed research she is conducting into gFSGS and nephrotic syndrome, presented at ASN Kidney Week.

Research 111
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Study shows no difference between two common methods for saving lives during cardiac arrest

Medical Xpress - Cardiology

There is no difference in the effectiveness of the two most commonly used methods for administering medication during out-of-hospital cardiac arrest.

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Study Links Sexual Trauma and Polygenic Scores to Severe Mental Illness

HCPLive

Sexual trauma and genetic risk independently and together raise mental illness risk, a new study found.

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Impact of aortic and pulmonary artery wall histology on radicular dilatation during the Ross procedure

Journal of Cardiothoracic Surgery

In our study, we aim to explore the structural differences between the aortic root and the pulmonary artery to better understand the process of pulmonary autograft dilatation during the Ross procedure.

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Stroke treatments explained

Medical Xpress - Cardiology

Each year, an estimated 15 million people around the globe experience stroke, according to the World Health Organization, with one-third resulting in death. That's why immediate stroke treatment is crucial.

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6-Year Pharmacovigilance Data Suggests Brodalumab Safe for Psoriasis Despite Boxed Warning

HCPLive

These data suggest brodalumab’s safety profile is consistent with findings from long-term clinical trials, with no new occurrences of suicide and a low rate of fungal infection.

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Examining apixaban vs aspirin in patients with cancer and cryptogenic stroke

Medical Xpress - Cardiology

Ochsner Health physicians Dr. Richard Zweifler and Dr. Joseph Tarsia are co-authors on a post hoc analysis carried out in the ARCADIA randomized clinical trial, comparing the effectiveness of apixaban versus aspirin in preventing adverse clinical outcomes in patients with a history of cancer and cryptogenic stroke. The research found no significant difference in the risk of major ischemic and hemorrhagic events between those taking apixaban and aspirin.

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Remo Panaccione, MD: Risankizumab Maintenance Therapy Efficacy, Dosing for Ulcerative Colitis

HCPLive

Panaccione provides insight into the efficacy of risankizumab maintenance therapy by induction outcomes and explains which dose may be more effective.

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Tougher limits on salt in packaged foods could save thousands of lives, study shows

Medical Xpress - Cardiology

Introducing tougher restrictions on sodium levels for packaged food could prevent thousands of deaths and save billions of dollars in health spending in Australia alone, a new study shows.

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'Wait-and-see' may produce worse outcomes for heart valve health: Study

Becker's Hospital Review - Cardiology

Traditionally, patients with a failing heart valve were advised to return in six to 12 months, as physicians generally took a "wait and see" approach, but a new study suggests patients may benefit more if their valves are replaced immediately through a minimally invasive procedure.

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Clinical Practice Algorithm For the Follow-Up of Unrepaired and Repaired Tetralogy of Fallot

American College of Cardiology

Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease (CHD). Early management of this condition is typically dictated by the degree of pulmonary stenosis (PS) and resulting oxygen saturations.

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Discussing 140-Week Data on Upadacitinib for Atopic Dermatitis, with Raj Chovatiya, MD, PhD

HCPLive

This interview from Fall Clinical featured a discussion of new findings on upadacitinib (Rinvoq) for patients with atopic dermatitis.

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Metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes: risk of heart failure

Cardiovascular Diabetology

The association between metabolic dysfunction-associated steatotic liver disease (MASLD) and cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM) is unclear. This study aimed to investigate.

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T-VASI, F-VASI are Reliable Tools to Measure Nonsegmental Vitiligo Progress

HCPLive

T-VASI and F-VASI are validated, responsive tools for assessing vitiligo severity and re-pigmentation, with meaningful change thresholds established.

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Personalized risk prediction of mortality and rehospitalization for heart failure in patients undergoing mitral valve repair surgery

Frontiers in Cardiovascular Medicine

BackgroundAccurately assessing the postoperative mortality and rehospitalization for heart failure risks in patients undergoing mitral valve repair surgery is of significant importance for individualized medical strategies.ObjectiveWe sought to develop and validate a risk assessment system for the prediction of mortality and rehospitalization for heart failure.MethodsPersonalized risk prediction system of mortality and rehospitalization for heart failure was developed.

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Hyperuricaemia elevates risk of short-term readmission and mortality in patients with heart failure

Open Heart

Background Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Serum uric acid (SUA), a product of purine metabolism, has been implicated in HF progression. However, the association between hyperuricaemia and the short-term readmission and mortality in patients with HF remains controversial. Methods In this retrospective cohort study, we analysed data from a HF database specific to the Chinese population.

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Tricuspid Valve Replacement Finds Surer Footing With TRISCEND II's 1-Year Report

Med Page Today

(MedPage Today) -- The Evoque transcatheter tricuspid valve replacement (TTVR) system continued to show significant benefits 1 year after implant, according to an update from the TRISCEND II trial. Among study participants with symptomatic, severe.

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Understanding an Enlarged Heart (Cardiomegaly): Causes, Symptoms, and Treatment

MIBHS

The heart is one of the most critical organs in the human body, responsible for pumping blood throughout the system to supply oxygen and nutrients. While a healthy heart maintains its size relative to the individual, conditions can cause it to enlarge—a condition known as cardiomegaly or an enlarged heart. An enlarged heart is not a disease but rather a symptom of an underlying issue.

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Cardioneuroablation eliminating cardiac asystole associated with area postrema syndrome: a case report and literature review

Frontiers in Cardiovascular Medicine

BackgroundThere have been few instances of symptomatic bradycardia-arrhythmia in the context of area postrema syndrome (APS), and some of them have been implanted permanent pacemakers. Cardioneuroablation (CNA) has emerged as a viable therapy for the treatment of syncope induced by neutrally mediated bradycardia or atrioventricular block.MethodsWe report a young patient with recurrent cardiac asystole and syncope following persistent hiccups caused by neuromyelitis optica spectrum disorder (NMOS

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Addressing Cardiovascular Risk in CKD Patients

HCPLive

In part 3 of this 5-part series, Lerma discusses recent updates in the management of chronic kidney disease in people with type 2 diabetes.

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IGF-1 levels in the general population, heart failure patients, and individuals with acromegaly: differences and projections from meta-analyses—a dual perspective

Frontiers in Cardiovascular Medicine

BackgroundThe complex relationship between insulin-like growth factor 1 (IGF-1) levels and heart failure (HF) is not fully understood, particularly across different populations and conditions. This meta-analysis aims to elucidate the dual perspectives of IGF-1 levels in the general population, HF patients, and individuals with treatment-naïve acromegaly, highlighting IGF-1 as a biomarker and potential therapeutic target in HF management.MethodsStudies were searched across multiple electronic dat

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CMS proposes implantable pulmonary artery pressure sensor coverage: 5 notes

Becker's Hospital Review - Cardiology

"CMS has proposed coverage of implantable pulmonary artery pressure sensors for heart failure management. Learn about the criteria and public comment period.

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Contemporary Outcomes of Endovascular Revascularization of Acute Limb Ischemia

American College of Cardiology

What are the contemporary outcomes and predictors of adverse events following endovascular treatment of acute limb ischemia (ALI) in a broad, nationwide, multicenter peripheral vascular registry?

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Applying Recent Guidelines, 4-Pillared Approach to CKD Care

HCPLive

In part 4 of this 5-part series, discussants explore the influence of recent guidelines on changing standards of CKD care.

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Impact of Catheter Ablation of Electrical Storm on Survival

American College of Cardiology

What is the impact of catheter ablation on the short- and mid-term survival of patients admitted for electrical storm?

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In vivo and vitro experiments show that long noncoding RNA treatment alleviates pathological cardiac hypertrophy

Medical Xpress - Cardiology

In a recent study, the regulatory role of the long noncoding RNA (lncRNA) Gm20257 in pathological cardiac hypertrophy has been elucidated, offering new insights into potential therapeutic targets. Pathological cardiac hypertrophy, a condition characterized by an abnormal increase in heart muscle size, can lead to heart failure if left unchecked.

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Titanium heart makes Time's 'Best Inventions' list

Becker's Hospital Review - Cardiology

The BiVACOR Total Artificial Heart is included on the 'The Best Inventions of 2024' list published Oct. 30 in Time.

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Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial

American College of Cardiology

The goal of the CLASP IID trial was to assess the safety and efficacy of the PASCAL system compared with the MitraClip among patients with degenerative mitral regurgitation (MR) who were at prohibitive surgical risk.

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Understanding the Effects of nsMRA vs MRA

HCPLive

In part 2 of this 5-part series, Lerma and Lala-Trindade discuss the key differences in MoA for nsMRA and MRAs.

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Feasibility and Safety of Pulsed Field Ablation at the Ventricular Outflow Tract Using Focal Point Catheter

HeartRhythm

Ventricular arrhythmias commonly originate from the ventricular outflow tract (VOT). It remains unexplored whether pulsed-field ablation (PFA) can create durable lesions safely at the VOT.