Sun.Jul 14, 2024

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The potential anti-arrhythmic effect of SGLT2 inhibitors

Cardiovascular Diabetology

Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) were initially recommended as oral anti-diabetic drugs to treat type 2 diabetes (T2D), by inhibiting SGLT2 in proximal tubule and reduce renal reabsorpti.

Diabetes 111
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Artificial intelligence-enabled atrial fibrillation detection using smartwatches: current status and future perspectives

Frontiers in Cardiovascular Medicine

Atrial fibrillation (AF) significantly increases the risk of stroke and heart failure, but is frequently asymptomatic and intermittent; therefore, its timely diagnosis poses challenges. Early detection in selected patients may aid in stroke prevention and mitigate structural heart complications through prompt intervention. Smartwatches, coupled with powerful artificial intelligence (AI)-enabled algorithms, offer a promising tool for early detection due to their widespread use, easiness of use, a

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Adjusting to a diagnosis you do NOT want to adjust to

Heart Sisters

I began to notice that my cardiac diagnosis seemed to alter my own best-before date - as if I'd been one person for 50+ years, and then overnight I became a different one I didn't recognize.

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Which of these, if either, is OMI? Which of these underwent emergent angiography and PCI? Which should have?

Dr. Smith's ECG Blog

Sent by anonymous, written by Pendell Meyers Case 1: A man in his 50s presented with acute chest pain. Normal vital signs. Here is his ECG at triage: What do you think? Here's what Version 1 QOH thinks: It is diagnostic of acute LAD OMI, with the precordial swirl pattern. See this post if you dont know that pattern yet: Precordial Swirl -- 20 cases of Swirl or Look-Alikes Here was a repeat ECG done within 20 minutes (still with ongoing pain): It still looks like active OMI to me, but perhaps sli

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Mendelian Randomization Links T1D to Increased Risk of Arthritis, MS

HCPLive

Results from a Mendelian randomization analysis indicate type 1 diabetes significantly increases the likelihood of autoimmune conditions like rheumatoid arthritis and multiple sclerosis.

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Cardiac involvement in Chagas disease and African trypanosomiasis

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 15 July 2024; doi:10.1038/s41569-024-01057-3 Infection with Trypanosoma spp. can cause Chagas disease or human African trypanosomiasis. In this Review, Sabino and colleagues discuss the effects of these infections on the heart, with particular emphasis on the pathogenesis, diagnosis and treatment of Chagas cardiomyopathy.

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Impact of pericardial calcification on early postoperative outcomes after pericardiectomy: a retrospective observational study

Journal of Cardiothoracic Surgery

Owing to the lack of understanding of the clinical significance of pericardial calcification during pericardiectomy, whether pericardial calcification should be considered when determining the optimal timing f.

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Lifelong dietary interventions linked to improved retinal health and reduced cardiovascular risk

Cardiology Update

In a recent study recently published in the European Heart Journal , researchers have found that the characteristics of retinal microvasculature can predict cardiovascular morbidity and mortality. The study delves into the associations between lifelong cardiovascular risk factors and the effects of dietary interventions on retinal microvasculature in young adulthood.

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Jacques-Eric Gottenberg, MD, PhD: Promising Phase 2 Results for Nipocalimab in Sjögren's Treatment

HCPLive

Jacques-Eric Gottenberg, MD, PhD, discusses the encouraging results of a phase 2 study evaluating nipocalimab for the treatment of Sjögren's syndrome.

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Spatially discordant alternans due to periodic pacing site alternation

HeartRhythm

Bidirectional ventricular tachycardia (BVT) is a rare type of ventricular tachycardia that is characterized by a beat-to-beat alternation in the QRS axis. Previous studies have shown that it is caused by alternating focal activities from two locations.

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COVID-19 Vaccination Shows Favorable Risk-Benefit in Sickle Cell

HCPLive

A study from the ASH Research Network reports positive antibody response and tolerability after mRNA vaccination in people with sickle cell disease.

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Unmasking the Trifascicular Left Intraventricular Conduction System by Selective Pacing from the Left Inferior (Posterior) Fascicle.

HeartRhythm

Nowadays it is recognized that in most human hearts, the left bundle branch (LBB) is divided into three fascicles: these are to be found in superior, septal and inferior positions.1,2 This classification has replaced the previous subdivision of the LBB into two fascicles (the left anterior and posterior fascicles) established by Rosenbaum and his group more than five decades ago.

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RF catheter ablation of AVNRT in a patient with interrupted inferior vena cava anomaly with hemiazygos continuity with persistent left superior vena cava

Journal of Cardiothoracic Surgery

Intrahepatic interruption of the inferior vena cava (IVC) with continued hemizygous is a very rare abnormality and sometimes it may be accompanied by other cardiovascular abnormalities. Continuation of the hem.

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EFFICACY AND SAFETY OF THE SUBCUTANEOUS IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR IN PATIENTS WITH AND WITHOUT OBESITY: A META-ANALYSIS

HeartRhythm

The subcutaneous implantable cardioverter-defibrillator (S-ICD) has emerged as an alternative to transvenous systems for preventing sudden cardiac death. However, concerns have been raised regarding its efficacy and safety in obese individuals.

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Reoperative approach after extra-anatomic ascending-to-descending aortic bypass graft

Journal of Cardiothoracic Surgery

Extra-anatomic ascending-to-descending aortic bypass grafts have historically been utilized as a safe and effective solution for repairs of complex coarctation of the aorta. However, reports on reoperation in.

Aortic 40
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Focal Aneurysm Formation in a Coronary Bypass Graft Following Permanent Pacemaker Implantation

HeartRhythm

Aneurysms, a vascular anomaly, can be classified based on their location and shape. Shear stresses, oscillatory shear index, gradient oscillatory number, and residence time serve as parameters to characterize the hemodynamics associated with the development and advancement of aneurysms. However, specific underlying causes and hemodynamic circumstances facilitating their formation and deteroration continue to be topics of active discussion.

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Long-Term Outcomes of Mechanical versus Bioprosthetic Aortic Valve Replacement in Patients Under 50 Years Old: Meta-Analysis of Reconstructed Time-to-Event Data

The American Journal of Cardiology

Publication date: Available online 14 July 2024 Source: The American Journal of Cardiology Author(s): Nav Warraich, Michel Pompeu Sá, Xander Jacqueymn, Danial Ahmad, Derek Serna-Gallegos, Ibrahim Sultan

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Causal inference in the field of arrhythmia: an introduction to Mendelian randomization

HeartRhythm

Mendelian randomization (MR) uses genetic variants associated with an exposure (e.g., high blood pressure) as instrumental variables to test causal effects on an outcome (e.g., atrial fibrillation (AF)). By leveraging the random assortment of genetic variants during gamete formation, MR reduces biases like confounding and reverse causation. We screened 391 papers, examining 278 that applied MR to investigate arrhythmia and, among others, cardiovascular traits, lifestyle, behavioral traits, body

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The Characteristics of Coronary Artery Lesions in COVID-19 Infected Patients with Coronary Artery Disease:An Optical Coherence Tomography Study

The American Journal of Cardiology

Publication date: Available online 14 July 2024 Source: The American Journal of Cardiology Author(s): Shan-Shan Ji, Li-Xuan Zhao, Weiqiang Chen, Yi-Fan Wang, Fang-Chun Liu, Hai-Peng Li, Guo-Wei He, Jian Zhang

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Chronic angiotensin converting enzyme inhibition attenuates frailty and protects against atrial fibrillation in aging mice

HeartRhythm

Aging is a major risk factor for atrial fibrillation (AF); however, not all individuals age at the same rate. Frailty, which is a measure of susceptibility to adverse health outcomes, can be quantified using a frailty index (FI).

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Working to Promote Health Equity: The Fourth Annual Disparities Issue

Circulation

Circulation, Volume 150, Issue 3 , Page 169-170, July 16, 2024.

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Feasibility, Safety and Short-Term Follow-Up Of Defibrillator Lead at Left Bundle Branch Area Pacing Location: A Pilot Study

HeartRhythm

Left bundle branch area pacing(LBBAP) has been increasingly adopted as an alternative modality for cardiac-resynchronization-therapy(CRT).

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Advancing Cardiovascular Health Equity With Artificial Intelligence: A Collective Ethical Responsibility

Circulation

Circulation, Volume 150, Issue 3 , Page 174-176, July 16, 2024.

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A Novel Diagnostic for Insulation Breach of Bipolar Pacemaker-Leads

HeartRhythm

The eye sees only what the mind is prepared to comprehend.

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“Asian” Heart Failure

Circulation

Circulation, Volume 150, Issue 3 , Page 177-179, July 16, 2024.

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Cardiac surgery during wartime in Israel

Journal of Cardiothoracic Surgery

The war that began on October 7th, 2023, has impacted all major tertiary medical centers in Israel. In the largest cardiac surgery department in Israel there has been a surprising increase in the number of ope.