Dr. Paddy Barrett

APRIL 11, 2025

More than heart disease or cancer, dementia is the primary concern for many of the patients I see. Heart disease and cancer attack your body, but dementia attacks your mind and identity. It strips away the fabric of who a person is. That is why I believe people fear dementia so much. Thankfully, 45% of all dementia is preventable 1. Many factors make up that 45%, but one factor seems to impact the risk of dementia the most.

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Dementia Exercise Cancer Heart Disease 76

Frontiers in Cardiovascular Medicine

APRIL 11, 2025

Unlike mammals, zebrafish can regenerate their heart after cardiac insult. There are several ways to perform cardiac injury in zebrafish, but cryoinjury most closely resembles human myocardial infarction (MI). Studies demonstrated that macrophages are essential cells from the beginning to later stages of cardiac injury throughout the regenerative process in zebrafish.

Myocardial Infarction 52

Myocardial Infarction 52

Hypertension Journal

APRIL 11, 2025

Hypertension, Ahead of Print. BACKGROUND:Aberrant BMPR2 (bone morphogenetic protein receptor 2) signaling is associated with the pathogenesis of pulmonary hypertension. SMAD4 is an essential downstream effector of BMPR2 signaling, but whether and how it participates in pulmonary hypertension are unclear.METHODS:Globally and vascular cell-specifically inducible knockout mouse models were used to examine the role of SMAD4 deficiency in differential cell compartments in the development of pulmonary

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Pulmonary Hypertension Aneurysm Aortic 40

Med Page Today

APRIL 11, 2025

(MedPage Today) -- The link between narcolepsy and cardiovascular disease (CVD) was strengthened by new evidence that the relationship applied to subclinical disease and was apparent early in life, based on a retrospective cohort study. Across.

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Cardiovascular Disease 86

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

HCPLive

APRIL 11, 2025

This analysis demonstrates the effectiveness of methotrexate application via microinfusion in frontal fibrosing alopecia.

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Medical Xpress - Cardiology

APRIL 11, 2025

Researchers from Queen Mary University of London have developed an AI tool that creates synthetic yet medically accurate models of fibrotic heart tissue (heart scarring), aiding treatment planning for atrial fibrillation (AF) patients. The study, published in Frontiers in Cardiovascular Medicine, could lead to more personalized care for patients affected by this common heart rhythm disorder.

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Atrial Fibrillation Heart Rhythm Research 66

Science Daily - Heart Disease

APRIL 11, 2025

Researchers have developed an AI tool that creates synthetic yet medically accurate models of fibrotic heart tissue (heart scarring), aiding treatment planning for atrial fibrillation (AF) patients. The study could lead to more personalized care for patients affected by this common heart rhythm disorder.

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HCPLive

APRIL 11, 2025

VERVE-102 is targeting the treatment of individuals with hyperlipidemia and high lifetime cardiovascular risk to reduce LDL-C levels.

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Journal of Cardiothoracic Surgery

APRIL 11, 2025

The Society for Vascular Surgery (SVS) guidelines recommend thoracic endovascular aortic repair (TEVAR) for blunt traumatic aortic injuries (BTAI) in adults, especially BTAI grades II to IV. TEVAR is increasin.

Aortic 52

Aortic Pediatrics 52

HCPLive

APRIL 11, 2025

These subgroup analysis findings on icotrokinra indicate that the drug is safe and effective among adolescents and adults with moderate-to-severe psoriasis.

Plaque 66

Plaque 66

Journal of Cardiothoracic Surgery

APRIL 11, 2025

Retained blood syndrome contributes to higher morbidity and mortality post cardiac surgery. We investigate the benefits of continuous postoperative pericardial flushing (CPPF) over standard care chest drainage.

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Med Page Today

APRIL 11, 2025

(MedPage Today) -- BOSTON -- In people with hypertension, a history of kidney stones may inform the choice of diuretic for stone prevention, according to a secondary analysis of the Diuretic Comparison Project. Among 1,164 older veterans with.

Hypertension 52

Hypertension 52

HCPLive

APRIL 11, 2025

Experts discuss the current place of JAK inhibitors in atopic dermatitis management, highlighting their role as an effective oral treatment option within the broader spectrum of therapies, including topical treatments and biologics, depending on disease severity and patient needs.

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Journal of Cardiothoracic Surgery

APRIL 11, 2025

Congenital heart disease may present with pectus excavatum. Concomitant and staged repair are described, but the optimal approach is controversial. We report a 17-year-old male with left aortic arch, aberrant.

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Congenital Heart Disease Congenital Aortic Heart Disease 40

HCPLive

APRIL 11, 2025

Experts discuss situations where an oral JAK inhibitor might be prescribed initially over a biologic for moderate to severe atopic dermatitis (AD), noting advantages such as oral administration, quicker onset of action, and convenience, which may make it a preferred option for some patients.

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Journal of Cardiothoracic Surgery

APRIL 11, 2025

Psychological factors are closely correlated with coronary heart disease, and gender discrepancies occurs in mental health after percutaneous coronary intervention (PCI) for acute coronary syndrome patients (A.

Heart Disease 40

Heart Disease Research 40

HCPLive

APRIL 11, 2025

Lafayette describes ongoing unmet needs in IgAN care and how the growing understanding of disease pathogenesis has informed drug development.

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Journal of Cardiothoracic Surgery

APRIL 11, 2025

to document the Egyptian experience with Ozaki procedure in adults and children and compare the clinical outcomes of the procedure to that of aortic valve replacement (AVRc) in adult patients.

Aortic valve 40

Aortic valve Aortic Pediatrics Document 40

HCPLive

APRIL 11, 2025

Ruff discusses his expectations for cardiology for the rest of 2025, including new research into GLP-1 receptor agonists.

Research 45

Research 45

American College of Cardiology

APRIL 11, 2025

Courtside with the Chair is a new series within CardiaCast presented by the Sports and Exercise Cardiology Member Section covering topics within the field of sports and exercise cardiology.

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Exercise Article 40

HCPLive

APRIL 11, 2025

Erickson discussed how federal travel restrictions put critical patient care and workforce stability at risk.

Patient Care 45

Patient Care 45

Clinical Trial Results

APRIL 11, 2025

Dr. Bhatt and I discuss ticagrelor reversal using bentracimab from the REVERSE-IT trial, as well as comparable efficacy and safety of rivaroxaban vs. warfarin for post-MI LV thrombus from the RIVAWAR trial.

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HCPLive

APRIL 11, 2025

Gelles discussed potential concerns with AIs use in reducing administrative burden but stressed its promise.

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The American Journal of Cardiology

APRIL 11, 2025

Publication date: Available online 11 April 2025 Source: The American Journal of Cardiology Author(s): Michael Megaly, Samer Zakhour, Mohamed Maki, Linda Albusoul, Asaad Nakhle, Judit Karacsonyi, Kambis Mashayekhi, Stephane Rinfret, Emmanouil S.

Cardiomyopathy 40

Cardiomyopathy 40

HCPLive

APRIL 11, 2025

Acute respiratory infection caused by RSV results in a nearly 3-fold increase in mortality, particularly in those with underlying respiratory conditions.

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NEJM Journal Watch - Cardiology

APRIL 11, 2025

Participants who completed the program maintained blood pressure control 42 months after enrollment.

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Blood Pressure Hypertension 40

HCPLive

APRIL 11, 2025

Payal Kohli, MD, explores how evolving tools and strategies in lipid management are reshaping preventive cardiology.

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Journal of the American Heart Association

APRIL 11, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundThe exercise assessment of the right ventricularpulmonary arterial (PA) coupling adds diagnostic and prognostic value in patients with heart failure. In patients with ischemic mitral regurgitation undergoing surgery, data on the exercise assessment of the right ventricularPA coupling are not available.

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Exercise Bicuspid/Mitral Outcomes Pulmonary 40

Medical Xpress - Cardiology

APRIL 11, 2025

A new study published in Nature Cardiovascular Research found that while carotid artery narrowing can lead to stroke in both men and women, the symptoms and plaque characteristics often differ between the sexes. Even though the main types of cells in the plaques are similar, important differences exist in the smaller structures within those cells.

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Plaque Stroke Strokes Research 119

Dr. Smith's ECG Blog

APRIL 11, 2025

While at ACC, I received this text message from a former resident: Good morning Steve! Hope youre doing well. Just curious what you think of this? He writes: "To me, the downsloping ST in V2/V3 is always OMI until proven otherwise. Also looks hyperacute inferior." "I activated cath lab, cardiologist is not impressed. Trop pending." Smith : "It is diagnostic of OMI!

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STEMI Angina Chest Pain Bradycardia 119

Physiologically Speaking

APRIL 11, 2025

Greetings! Welcome to the Physiology Friday newsletter. I want to take a brief moment to plug a product and company I’ve been obsessed with—and give you a chance to try them out! A few weeks ago, I downloaded an app on my iPhone that uses the FaceID camera (the same tech Apple uses to unlock your iPhone or iPad) to scan my feet and make custom running insoles.

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Exercise Physiology Research Download 64

NEJM Journal Watch - Cardiology

APRIL 11, 2025

A new guideline recommends short duration of DAPT if bleeding risk is high and advises bivalirudin instead of heparin for PCI.

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HCPLive

APRIL 11, 2025

Dual-energy computed tomography results in faster dissolution of both the core and crown of tophi.

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Ultrasound Research 59

Dr. S. Venkatesan MD

APRIL 11, 2025

1. Is systemic HT an advantage, so that high pressure head aids in pushing the blood across the lesion ? I don’t know whether I can say Yes*, physiologically, the high proximal pressure and low distal pressure help maintain the flow. The distal drop happens due to the tightness of the lesion itself, but that is counterproductive, unless tone of the distal microvascular bed is intact and dilates fully.

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Cardiogenic Shock Arterioles Ischemia Physiology 52

CardiacWire

APRIL 11, 2025

Data analysis from the NODE-301 Phase 3 trial suggests that patients self-adminstering Milestone Pharmaceuticals etripamil (CARDAMYST) might be able to avoid ER visits for paroxysmal supraventricular tachycardia (PSVT). PSVT includes a range of heart-rhythm disorders and occurs in 1 out of 300 patients, leading to unpredictable elevated heart rates that require medical intervention.

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Tachycardia Heart Rhythm Research 52

HCPLive

APRIL 11, 2025

A panelist discusses how their traditional treatment approach for severe alopecia areata typically involved a stepped care pathway beginning with topical and intralesional steroids before progressing to systemic immunosuppressants or immunotherapy, which often yielded inconsistent, temporary, or incomplete hair regrowth results, leaving significant unmet needs for treatments that could provide sustained efficacy, acceptable safety profiles, and therapies specifically developed for this condition

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