Tue.Jul 23, 2024

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Australian Medtech EMVision Unveils Backpack-Sized Brain Scanner to Empower First Responders

DAIC

EMVision's First Responder device aims to fundamentally transform stroke and traumatic brain injury outcomes for all patients, regardless of their location, by delivering sophisticated neurodiagnostic technology directly to the point of care (Photo: Business Wire) mtaschetta-millane Tue, 07/23/2024 - 10:36 July 23, 2024 — EMVision , an Australian medical device company focused on the development and commercialization of innovative portable brain scanning technology, has today unveiled its First

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Empowering Patients with Educational Resources for Kidney Disease, with Mike Spigler

HCPLive

Spigler provides insight into the development of new patient-focused guidelines for managing hyperkalemia in CKD and the importance of providing patients with such resources.

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International Atherosclerosis Society Issues New White Paper Underscoring Inflammation's Role, Offering Key Recommendations

DAIC

The International Atherosclerosis Society (IAS) has released a clinical proceedings white paper outlining the role of inflammation in atherosclerosis and the importance of early intervention. The paper is part of IAS’ Clinical Proceedings, a white paper series, which offers informational resources intended to raise awareness and address unmet needs in atherosclerosis.

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A prehospital ECG in a patient with chest pain. The paramedics tell me it is normal.

Dr. Smith's ECG Blog

I was working at triage when the medics brought this patient who is 65 yo and has had chest pain for 12 hours. They recorded a prehospital ECG at 2112 and said that it was “normal”. It had already been crumpled up and put in the waste basket. So I uncrumpled it: What do you think? You need to click on it to enlarge it to view it well I was suspicious for inferior and posterior OMI (Large T-wave in aVF, slight STE in lead III with inverted T-wave in aVL, and a slightly downsloping ST with negativ

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Dapagliflozin and Right Ventricular Pulmonary Vasculature in HFpEF

JAMA Cardiology

This randomized clinical trial investigates the effect of dapagliflozin on right ventricular performance and vascular load during exertion in heart failure with preserved ejection fraction (HFpEF).

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Few Youth Receive Lipid Screening, Highlighting Missed Opportunity to Reduce CVD Risk

HCPLive

Despite recommendations, an analysis of more than 3.2 million youths suggests fewer than 15% of children/adolescents receive lipid screening.

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Brain-heart axis: Strokes change epigenetics of immune system

Science Daily - Heart Disease

A stroke not only causes acute damage to the brain, but can also have long-term health implications for other organs -- such as the heart. Researchers have worked on the hypothesis that the high rate of comorbidities that develop after a stroke could have a common immunological cause. And they actually managed to find it: The origin of the dysfunctions in other parts of the body lies in the immunological memory of the blood-forming cells in bone marrow.

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Children with Cerebral Palsy Have More Anxiety Than Those Without this Disorder

HCPLive

A study found children and young adults with cerebral palsy have more anxiety and less depression than those with a chronic condition or who are typically developed.

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How does the brain respond to sleep apnea?

Science Daily - Heart Disease

Nearly 40 million adults in the U.S. have sleep apnea, and more than 30 million of them use a continuous positive airway pressure (CPAP) machine while sleeping. However, the machines tend to be expensive, clunky and uncomfortable -- resulting in many users giving up on using them. High blood pressure is often linked with sleep apnea because the brain works harder to regulate blood flow and breathing during sleep.

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Gout Prevalence Estimated to Increase More Than 70% by 2050

HCPLive

The number of prevalent gout cases is projected to reach 95.8 million by 2050, with population growth cited as the largest contributor.

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Blood pressure high for years? Beware of stroke risk

Science Daily - Heart Disease

Years of high systolic blood pressure are linked to a greater risk for the two most common types of stroke. The results suggest that early diagnosis and sustained control of high blood pressure over the lifespan are critical to preventing stroke, especially in Black and Hispanic patients who are more likely to have uncontrolled hypertension.

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The top heart hospital in every state

Becker's Hospital Review - Cardiology

Discover the top heart hospitals in every state according to U.S.

Hospital 124
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ACC BOT Confirms 2025 Slate of New Officers and Trustees

American College of Cardiology

The ACC Board of Trustees (BOT) has approved the College's newest officers and trustees who will assume their roles in March 2025 following ACC.25 in Chicago, IL.

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Noninvasive Visualization of the Atrioventricular Conduction System

JAMA Cardiology

This cohort study investigates if contrast-enhanced cardiac computed tomography can localize the atrioventricular conduction system through the identification of the insular fat of the conductive myocardium.

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Mortality After Procedural or Spontaneous MI

American College of Cardiology

What is the impact of procedural myocardial infarction (pMI) and spontaneous myocardial infarction (spMI) across different levels of troponin elevation on mortality among patients undergoing percutaneous coronary intervention (PCI)?

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Financial incentives improve cardiac rehab participation: Study

Becker's Hospital Review - Cardiology

Financial incentives increase patient participation in cardiac rehabilitation programs, according to a clinical trial published July 22 in JAMA Internal Medicine.

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Preeclampsia Blood Marker? Pediatric Cardiac Doc Arrested; Afib-Detecting Ring

Med Page Today

(MedPage Today) -- Expectant mothers might one day be able to take a blood test to predict their risk of preeclampsia late into pregnancy. (Scientific Reports) A higher BMI starting at age 20 was tied to worse diastolic function, independent of.

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Taking Both CYP2D6 Opioids and Antidepressants Leads to Risk for Older Adults

HCPLive

A study shows it is safer for nursing home residents on CYP2D6 opioids to take CYP2D6-neutral antidepressants than CYP2D6-inhibiting antidepressants.

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Eat Food, Not Too Much, Mostly Plants: Nutrition and CVD

American College of Cardiology

In this interview, Robert Ostfeld MD, MSc, FACC and Alison L. Bailey, MD FACC explore the vital link between nutrition and cardiovascular health.

Article 65
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Arcutis Submits sNDA for Roflumilast Foam as Treatment for Scalp, Body Psoriasis

HCPLive

This supplemental new drug application for once-daily roflumilast foam follows positive results of the ARRECTOR phase 3 study.

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Role of long noncoding RNAs in diabetes-associated peripheral arterial disease

Cardiovascular Diabetology

Diabetes mellitus (DM) is a metabolic disease that heightens the risks of many vascular complications, including peripheral arterial disease (PAD). Various types of cells, including but not limited to endothel.

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Reactive oxygen species in hypertension

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 24 July 2024; doi:10.1038/s41569-024-01062-6 In this Review, Touyz and colleagues discuss the role of reactive oxygen species in the pathophysiology of hypertension, focusing on the mechanisms of reactive oxygen species generation and oxidative stress in hypertension, as well as the alterations in redox signalling.

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Case Report: Allograft aortic valve replacement in irreparable infant mitral valve

Frontiers in Cardiovascular Medicine

This case report describes a 3-month-old male infant diagnosed with severe mitral stenosis (MS) and mitral regurgitation (MR) by transthoracic echocardiography. The male infant initially underwent complex mitral valve repair surgery. However, postoperative deterioration occurred with hemodynamic instability and shock, necessitating multiple resuscitation efforts and ultimately requiring support from Extracorporeal Membrane Oxygenation (ECMO).

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Early Career Journey: Making the Most of the STS Annual Meeting

Society of Thoracic Surgeons - Early Career

Webinar Early Career Journey: Making the Most of the STS Annual Meeting gmckinney Tue, 07/23/2024 - 08:15 December 12, 2024 Learn how to take advantage of everything the STS Annual Meeting has to offer, from educational sessions and networking opportunities. Special focus will be given to trainees and first-time attendees. This program is part of the STS series of quarterly Early Career Journey webinars, sponsored by The Hub: Resources and Community for Your Early Career Journey.

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A network meta-analysis: evaluating the efficacy and safety of concurrent proton pump inhibitors and clopidogrel therapy in post-PCI patients

Frontiers in Cardiovascular Medicine

IntroductionThe objective of this research was to evaluate the risk of major adverse cardiovascular events (MACEs) associated with the use of various proton pump inhibitors (PPIs) in combination with clopidogrel in patients who underwent percutaneous coronary intervention (PCI).MethodsTo accomplish this, we analyzed data from randomized controlled trials and retrospective cohort studies sourced from key electronic databases.

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Arshad Khanani, MD: Four-Year Outcomes of Faricimab for DME in RHONE-X

HCPLive

Presented at ASRS 2024, late-breaking RHONE-X data shows more than 90% of patients experienced the absence of DME after four years of faricimab.

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'Holiday heart syndrome': Researchers explore binge drinking and arrhythmia link at times of celebration

Medical Xpress - Cardiology

Binge drinking (five drinks within two hours for men and four drinks within two hours for women) is common around the world. Recent research has also found the incidence of atrial fibrillation (AFib), the most common type of irregular heart rhythm or arrhythmia, continues to rise, according to the study.

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Anxiety Plays a Significant Role in Physical Activity Avoidance Among Patients with PsA

HCPLive

Independent predictors of physical activity avoidance were anxiety symptoms—as determined by HADS—and the SF-36 Physical Component Score.

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Fenestrated-Branched Endovascular Thoracoabdominal AA Repair

American College of Cardiology

What are the aortic-related mortality (ARM) and the risk of aortic aneurysm (AA) rupture after fenestrated-branched endovascular aortic repair (FB-EVAR) for the treatment of thoracoabdominal aortic aneurysm (TAAA)?

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FDA Accepts sBLA for Susvimo in Treatment of DME, Diabetic Retinopathy

HCPLive

The FDA accepted Genentech’s supplemental BLA for Susvimo, based on the one-year results from the Phase III Pagoda and Pavilion studies.

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Lp(a) and Calcific Aortic Valve Stenosis Progression

American College of Cardiology

What is the association between plasma lipoprotein(a) [Lp(a)] concentrations and hemodynamic progression in patients with aortic stenosis?

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Statins May Prevent Fibrosis Risk Progression in MASLD, Study Finds

HCPLive

Primary care patients with MASLD who received a prescription for moderate- and high-intensity statins had a lower risk of progressing to a high-risk FIB-4 score.

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The Politics of HFpEF—What’s Good for the Left Is Good for the Right

JAMA Cardiology

Among patients with heart failure with preserved ejection fraction (HFpEF), right ventricular (RV) dysfunction is strongly associated with an increased risk of morbidity and mortality. The RV is especially sensitive to afterload, and abnormalities in the pulmonary circulation leading to increased RV afterload may play a critical role in driving the exercise intolerance and high risk of hospitalization characteristic of HFpEF.

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Ruxolitinib Cream Led to Meaningful Repigmentation Across Different Body Regions

HCPLive

Following this pooled analysis, there may be a need for additional research conducted to identify other targets for achievement of optimal repigmentation.

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The combination of valsartan and spironolactone mitigated mitral regurgitation induced cardiac dysfunction in a novel rat model

Journal of Cardiovascular Pharmacology

Despite its high prevalence, effective treatment for degenerative mitral regurgitation (MR) remains elusive. Although the mineralocorticoid-receptor antagonist spironolactone, in conjunction with renin-angiotensin system (RAS) inhibitors, has been shown to reduce mortality in patients with heart failure with reduced ejection fraction (HFrEF), its efficacy in managing degenerative MR is uncertain.

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Investigating hormonal influence of ethanol-evoked cardiac oxidative stress and dysfunction in women

Medical Xpress - Cardiology

The hormone estrogen helps keep blood vessels open and flexible and is generally thought to help protect women from heart disease. These higher estrogen levels may lead to fewer heart attacks and strokes in premenopausal women than in men of the same age.

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Effect of extracellular matrix stiffness on efficacy of Dapagliflozin for diabetic cardiomyopathy

Cardiovascular Diabetology

Extracellular matrix (ECM) stiffness is closely related to the progress of diabetic cardiomyopathy (DCM) and the response of treatment of DCM to anti-diabetic drugs. Dapagliflozin (Dapa) has been proven to hav.