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(MedPage Today) -- NEW ORLEANS -- Patients with type 2 diabetes (T2D) hospitalized for ketoacidosis had a higher mortality rate versus patients with type 1 diabetes (T1D), according to a study of national data. In the retrospective study, the.
A 53-year-old woman with the dilated phase of hypertrophic cardiomyopathy underwent orthotopic heart transplantation. The donor heart was evaluated as normal preoperatively without mitral regurgitation or the.
Cardiovascular diseases (CVD) are the leading cause of death worldwide, despite advances in understanding cardiovascular health. Significant barriers still exist in effectively preventing and managing these diseases. Vascular smooth muscle cells (VSMCs) are crucial for maintaining vascular integrity and can switch between contractile and synthetic functions in response to stimuli such as hypoxia and inflammation.
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Cardiac amyloidosis is a group of diseases characterized by the deposition of amyloid fibers in cardiac tissue. Two forms are mainly reported: light chain (AL) and transthyretin (ATTR) amyloidosis. Among the complications of transthyretin amyloidosis there are thrombotic events and, to a lesser extent, hemorrhagic events. The latter are likely caused by perivascular amyloid deposition resulting in capillary fragility, in addition to INR lability during anticoagulant therapy.
Ataxia Neuropathy Spectrum (ANS) represents a complex array of neurological disorders primarily associated with POLG gene mutations. This case report examines a 25-year-old male patient presenting with a compound homozygous POLG1 mutation c.2243G>C, encoding p.Trp748Ser. Despite lacking typical clinical features of Mitochondrial Autosomal Recessive Ataxia Syndrome (MIRAS) or Sensory Ataxia Neuropathy Dysarthria and Ophthalmoplegia (SANDO), the patient exhibited progressive neurological sympto
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Left atrial appendage closure (LAAC) is an alternative to reduce thrombotic risk in patients with non-valvular atrial fibrillation. Conventionally this procedure requires the use of a contrast agent. A significant proportion of patients who underwent this procedure have chronic kidney disease, presenting a high risk of contrast-induced nephropathy.
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Publication date: Available online 11 May 2024 Source: The American Journal of Cardiology Author(s): Osamah Badwan, Felix Berglund, Akiva Rosenzveig, Ian Persits, Ahmad Gharaibeh, Ashwin Kumar, Ankit Agrawal, Lidiya Sul, Nicholas Chan, Tom Kai Ming Wang, Mazen Hanna, Allan L.
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