Thu.Sep 28, 2023

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Healing Hearts and Inspiring Change: Celebrating World Heart Day

ADN Center of Excellence

Every year, on September 29th, the world unites to celebrate World Heart Day. This day serves as a reminder of the vital role our hearts play in keeping us alive and healthy. For cardiologists, it's a moment to reflect on their dedication to heart health and share valuable insights with the world. World Heart Day World Heart Day was established by the World Heart Federation to raise awareness about cardiovascular diseases (CVD) and promote heart-healthy lifestyles.

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Exposure to air pollution linked to increased risk of stroke within 5 days

Science Daily - Stroke

Short-term exposure to air pollution may be linked to an increased risk of stroke. Short-term exposure was defined as occurring within five days of the stroke.

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Overexpression of human soluble epoxide hydrolase exacerbates coronary reactive hyperemia reduction in Angiotensin-II treated mouse hearts

Journal of Cardiovascular Pharmacology

Coronary reactive hyperemia (CRH) is impaired in cardiovascular diseases, and angiotensin-II (Ang-II) exacerbates it. However, it is unknown how Ang-II affects CRH in Tie2-sEH Tr (human-sEH-overexpressed) versus wild-type (WT) mice. sEH-overexpression resulted in CRH-reduction in Tie2-sEH Tr versus WT. We hypothesized that Ang-II exacerbates CRH-reduction in Tie2-sEH Tr versus WT.

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Treatment of Traumatic Direct Carotid Cavernous Fistula With a PK Papyrus Covered Stent: A Report of 2 Cases

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023. BackgroundTraumatic direct carotid cavernous fistulas results in a direct communication between the internal carotid artery and the cavernous sinus. Covered stents are not frequently used in neuro‐endovascular procedures due to concerns primarily about occlusion of perforating vessels.

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Salt Sensitivity of Blood Pressure in Black People: The Need to Sort Out Ancestry Versus Epigenetic Versus Social Determinants of Its Causation: Salt Series

Hypertension Journal

Hypertension, Ahead of Print. Race is a social construct, but self-identified Black people are known to have higher prevalence and worse outcomes of hypertension than White people. This may be partly due to the disproportionate incidence of salt sensitivity of blood pressure in Black people, a cardiovascular risk factor that is independent of blood pressure and has no proven therapy.

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Effect of Endovascular Treatment in HERMES Patients With Isolated Occlusion of the Intracranial Internal Carotid Artery

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023. BackgroundThe optimal management of patients with symptomatic isolated internal carotid artery (ICA) occlusion is unknown. We aimed to assess whether endovascular treatment (EVT) compared with standard medical care was associated with improved functional outcomes in patients with acute symptomatic isolated intracranial ICA occlusion without involvement of the middle or anterior cerebral artery, that is, ICA‐I oc

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Nanoparticle-Based Therapies in Hypertension

Hypertension Journal

Hypertension, Volume 80, Issue 12 , Page 2506-2514, December 1, 2023. Nearly 1.4 billion people worldwide suffer from arterial hypertension, a significant risk factor for cardiovascular disease which is now the leading cause of death. Despite numerous drugs designed to treat hypertension, only ≈14% of hypertensive individuals have their blood pressure under control.

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Reduced Brain Cortex Angiogenesis in the Offspring of the Preeclampsia-Like Syndrome

Hypertension Journal

Hypertension, Volume 80, Issue 12 , Page 2559-2571, December 1, 2023. BACKGROUND:Children from pregnancies affected by preeclampsia have an increased risk of cognitive and behavioral alterations via unknown pathophysiology. We tested the hypothesis that preeclampsia generated reduced brain cortex angiogenesis in the offspring.METHODS:The preeclampsia-like syndrome (PELS) mouse model was generated by administering the nitric oxide inhibitor NG-nitroarginine methyl ester hydrochloride.

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Unmasking Transthyretin Cardiac Amyloidosis Following Transcatheter Aortic Valve Implantation

Circulation: Heart Failure

Circulation: Heart Failure, Ahead of Print.

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Genetic Contribution to End-Stage Cardiomyopathy Requiring Heart Transplantation

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 452-461, October 1, 2023. Background:Many cardiovascular disorders propel the development of advanced heart failure that necessitates cardiac transplantation. When treatable causes are excluded, studies to define causes are often abandoned, resulting in a diagnosis of end-stage idiopathic cardiomyopathy.