Mon.Sep 02, 2024

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Clinical trial finds finerenone reduces worsening heart failure and cardiovascular death

Science Daily - Heart Disease

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial.

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Afib Ablation Delivers in First Sham-Controlled Study

Med Page Today

(MedPage Today) -- LONDON -- Pulmonary vein isolation (PVI) produced real short-term improvements for people with atrial fibrillation (Afib or AF), according to the first sham-controlled trial on the subject. Continuous monitoring by implantable.

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Seizure in a 30 something

Dr. Smith's ECG Blog

Written by Magnus Nossen — with edits by Grauer. The patient in today’s case is a 30-something female. She has no known previous medical history. Her husband called EMS when the patient experienced new onset seizures accompanied by micturition. The ECG below was recorded by EMS. What is your assessment? ECG #1 Interpretation: ECG #1 shows sinus rhythm at a heart rate of 77 bpm.

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Rare genetic variants linked to bicuspid aortic valve disease in young adults identified

Medical Xpress - Cardiology

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

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Don't Miss a Beat: Finerenone's Role in Heart Failure from ESC Congress Data

HCPLive

In this episode, Muthiah Vadugnathan, MD, MPH, and Stephen Greene, MD, discusses finerenone and MRA data from ESC Congress 2024

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Beta-blockers do not affect patients' quality of life, study finds

Medical Xpress - Cardiology

Long-term use of beta-blockers in patients with myocardial infarction and preserved heart function does not significantly change quality of life or well-being compared to no beta-blockers. This is according to a study from Karolinska Institutet and Uppsala University, presented at the European Society of Cardiology's annual congress in London and simultaneously published in the European Heart Journal—Cardiovascular Pharmacotherapy.

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PALISADE: Plozasiran Offers Hope for Treating Familial Chylomicronemia Syndrome

HCPLive

ESC 2024: Phase 3 PALISADE trial shows plozasiran significantly lowers triglycerides and pancreatitis risk in FCS; NDA planned by year-end.

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Kausik Ray, MD, MPhil: INTERASPIRE and the Expanding Knowledge Base for Lipoprotein(a)

HCPLive

Kausik Ray, MD, MPhil, discusses the results of the INTERASPIRE study and how it improves our understanding of the effects of elevated Lp(a).

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National AFib Awareness Month: A Call to Action for Physicians Worldwide

ADN Center of Excellence

September is National Atrial Fibrillation (AFib) Awareness Month, a time dedicated to raising awareness about one of the most common yet often misunderstood heart conditions. Physicians have a crucial role in recognizing, diagnosing, and managing AFib to prevent its potentially life-threatening complications. Understanding Atrial Fibrillation Atrial Fibrillation is characterized by an irregular and often rapid heart rhythm that can lead to poor blood flow.

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Unmet Needs and Gaps in AD

HCPLive

Dermatologists outline unmet needs in the treatment landscape for atopic dermatitis and discuss how to potentially improve the standard of care for patients with atopic dermatitis.

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National AFib Awareness Month: A Call to Action for Physicians Worldwide

ADN Center of Excellence

September is National Atrial Fibrillation (AFib) Awareness Month, a time dedicated to raising awareness about one of the most common yet often misunderstood heart conditions. Physicians have a crucial role in recognizing, diagnosing, and managing AFib to prevent its potentially life-threatening complications. Understanding Atrial Fibrillation Atrial Fibrillation is characterized by an irregular and often rapid heart rhythm that can lead to poor blood flow.

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Relationships between ankle blood pressure indices and major adverse cardiovascular events in people with and without type 2 diabetes

Cardiovascular Diabetology

The relationship between ankle blood pressure (BP) and cardiovascular disease remains unclear. We examined the relationships between known and new ankle BP indices and major cardiovascular outcomes in people w.

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Descriptive analysis of therapeutic outcomes between thoracoscopic and transsternal thymectomy in myasthenia gravis patients from 2011 to 2021

Journal of Cardiothoracic Surgery

Myasthenia gravis is an autoimmune disease with high prevalence of thymus disorders, in which, thymectomy is considered one of the therapeutic approaches in improving the patients’ clinical outcomes. Today, th.

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Exploring the mortality and cardiovascular outcomes with SGLT-2 inhibitors in patients with T2DM at dialysis commencement: a health global federated network analysis

Cardiovascular Diabetology

Sodium-glucose cotransporter 2 inhibitors (SGLT-2is) have demonstrated associations with lowering cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM). However, the impact of SGLT-2is on in.

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Midterm outcome after surgical correction of an anomaly of the left coronary artery from the pulmonary artery

Journal of Cardiothoracic Surgery

Objective This study aims to present the midterm outcomes of surgical correction of the anomalous left coronary artery from the pulmonary artery (ALCAPA). Methods This is a retrospective study of patients undergoing anomalous origin of the LCA from the pulmonary artery repair between 2010 and 2019. Results Forty-nine patients (20 boys and 29 girls) underwent ALCAPA repair.

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Fenofibrate to prevent amputation and reduce vascular complications in patients with diabetes: FENO-PREVENT

Cardiovascular Diabetology

The potential preventive effect of fenofibrate on lower extremity amputation (LEA) and peripheral arterial disease (PAD) in patients with type 2 diabetes (T2D) is not fully elucidated.

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Wolf in sheep’s clothing: a case of primary lung adenosquamous carcinoma mimicking traumatic pulmonary pseudocyst

Journal of Cardiothoracic Surgery

Traumatic pulmonary pseudocyst is a rare “cystlike” lung lesion that typically develops following blunt chest trauma. It differs from lung cancer associated with cystic airspaces in terms of pathogenic mechani.

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Drug-Coated Balloon Flops for De Novo Coronary Lesions

Med Page Today

(MedPage Today) -- LONDON -- Drug-coated balloon (DCB) angioplasty as the initial strategy for de novo coronary artery stenoses didn't measure up to stenting from the start, the REC-CAGEFREE I randomized trial showed. DCB with rescue use of.

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EMPACT-MI Kidney: SGLT2 Initiation Can Preserve Kidney Function in Post-MI Population

HCPLive

EMPACT-MI study shows empagliflozin is safe post-acute MI and reduces heart failure events, with kidney protection across kidney function levels.

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Optical Coherence Tomography-Guided Coronary Intervention in Patients With Complex Lesions

American College of Cardiology

The goal of the OCCUPI trial was to compare optical coherence tomography (OCT)-guided versus angiography-guided percutaneous coronary intervention (PCI) of complex coronary lesions.

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Changing Standard of Care in Atopic Dermatitis

HCPLive

The panel provides comprehensive insights on treating atopic dermatitis and how recent advances have elevated standard-of-care treatment practices in dermatology practices.

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Percutaneous Coronary Intervention With a Bioadaptor Compared to a Contemporary Drug-Eluting Stent

American College of Cardiology

The goal of the INFINITY-SWEDEHEART trial was to compare the efficacy of the DynamX bioadaptor, a novel coronary implantable device, to a contemporary drug-eluting stent (DES) in the treatment of coronary artery disease requiring percutaneous coronary intervention (PCI).

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Experts develop global consensus document on atrial cardiomyopathy

Medical Xpress - Cardiology

An international cardiology working group has published a consensus report on atrial cardiomyopathy in Europace. Twenty-one scientists from the rhythmological societies of Europe (European Heart Rhythm Association), North America (Heart Rhythm Society), South America (Latin American Heart Rhythm Society) and the Asia-Pacific region (Asia Pacific Heart Rhythm Society APHRS) were involved.

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Drug-Coated Balloon Angioplasty With Rescue Stenting Versus Intended Stenting for the Treatment of Patients With de Novo Coronary Artery Lesions

American College of Cardiology

The goal of the REC-CAGEFREE I trial was to assess the safety and efficacy of a paclitaxel-coated balloon (DCB) compared to drug-eluting stent (DES) implantation among patients with coronary in-stent restenosis.

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Clinical trial confirms that fasting is not needed before catheterization lab procedures

Medical Xpress - Cardiology

There was no difference in complications in patients who fasted or did not fast before cardiac catheterization procedures requiring conscious sedation, according to late-breaking research presented in a Hot Line session Sept. 1 at ESC Congress 2024.

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OCCUPI: OCT-Guided PCI vs. Angiography-Guided PCI in Patients Requiring DES For Complex Lesions

American College of Cardiology

Optical coherence tomography (OCT) guidance during PCI resulted in a lower incidence of major adverse cardiac events at one year in patients requiring drug-eluting stent (DES) implantation for complex lesions, compared with angiography guidance, based on findings from the OCCUPI trial.

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Device-detected atrial fibrillation: Anticoagulation may have greater benefit in patients with vascular disease

Medical Xpress - Cardiology

A combined subgroup analysis of the similar trials NOAH—AFNET 6 and ARTESiA has revealed that patients with device-detected atrial fibrillation and concomitant vascular disease are at higher risk of stroke and cardiovascular events and may derive a greater benefit from oral anticoagulation than those without vascular disease.

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Successful mediastinal teratoma resection in a child by assisted VATS: a case report

Journal of Cardiothoracic Surgery

Video-assisted thoracic surgery (VATS) is widely used for thoracic lesions in pediatric patients. VATS is also applied to pediatric mediastinal tumors if there is no adhesion or invasion between the tumor and.

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Trial finds drug-coated balloon angioplasty less effective than second generation drug-eluting stents

Medical Xpress - Cardiology

Novel drug-coated balloons (DCB) did not outshine standard treatment with second generation drug-eluting stents (DES) as they were expected to, in a surprise finding of the first randomized trial to compare clinical outcomes in previously untreated patients with non-complex disease undergoing percutaneous coronary intervention (PCI). The study was presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug.–2 Sept.).

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Development and validation of a predictive model for atrial fibrillation recurrence post-catheter ablation in non-valvular atrial fibrillation patients based on hemodynamic parameters

HeartRhythm

The influence of hemodynamic parameters on the recurrence of atrial fibrillation (AF) following catheter ablation is not well known, and it remains unclear whether a nomogram combining risk factors and hemodynamic parameters improves prediction accuracy.

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Simplified atrial fibrillation ablation technique benefits heart failure patients

Medical Xpress - Cardiology

Cryoballoon (CB) ablation is as effective at reducing recurrences of atrial fibrillation (AF) and atrial tachycardia (AT) at 1-year, when compared to the current most widely used technique, radiofrequency (RF) ablation, in heart failure patients with a reduced ejection fraction (HFrEF), according to late breaking research presented in a Hot Line Session on Sept. 2 at this year's ESC Congress 2024.

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REC-CAGEFREE I: DCB Angioplasty With Rescue Stenting vs. Intended DES in Patients With de novo Noncomplex Coronary Artery Lesions

American College of Cardiology

A strategy of drug-coated balloon (DCB) angioplasty with rescue stenting did not achieve noninferiority compared with intended drug-eluting stent (DES) deployment for patients with de novo, noncomplex coronary artery lesions, according to finding from the REC-CAGEFREE I trial presented at ESC Congress 2024 in London and simultaneously published in The Lancet.

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First randomized trial shows education for health care professionals can improve guideline implementation

Medical Xpress - Cardiology

Adherence to atrial fibrillation (AF) guideline recommendations was found to be poor in clinical practice across Europe, but a structured educational program for health care professionals improved implementation of heart rhythm control recommendations in patients, according to late-breaking research presented in a Hot Line session Sept. 1 at the ESC Congress 2024 and concurrently published in Europace.

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Re-engineering the Clinical Approach to Suspected Cardiac Chest Pain Assessment in the Emergency Department by Expediting Evidence to Practice Using Artificial Intelligence

American College of Cardiology

The goal of the RAPIDxAI trial was to determine the efficacy and safety of an artificial intelligence (AI)-based clinical decision support tool compared with usual care in the diagnosis and management of emergency department (ED) patients with elevated high-sensitivity cardiac troponin (hs-cTn).

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New evidence for benefits of transcatheter edge-to-edge repair in secondary tricuspid regurgitation

Medical Xpress - Cardiology

Tricuspid transcatheter edge-to-edge repair (T-TEER) significantly reduced the severity of secondary tricuspid regurgitation and improved quality of life after one year, according to research presented in a Hot Line session August 31 at ESC Congress 2024.

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PROTEUS and RAPIDxAI Studies Explore Use of AI in the ED

American College of Cardiology

Two late-breaking studies presented at ESC Congress 2024 in London looked at the use of artificial intelligence (AI) to aid in the identification of patients undergoing a stress echocardiogram who could benefit from further treatment, and to help with identifying and managing myocardial infarction (MI) in patients presenting to the emergency department (ED).

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Trial investigates use of invasive strategy to treat older patients after non-ST-elevation myocardial infarction

Medical Xpress - Cardiology

An invasive strategy vs. optimal medical therapy alone after a non-ST-elevation myocardial infarction (NSTEMI) in older adults did not affect the combined risk of cardiovascular death or MI, although non-fatal MIs and subsequent revascularization procedures were reduced, according to late-breaking research presented in a Hot Line session Sept. 1 at ESC Congress 2024.