This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
Nature Reviews Cardiology, Published online: 19 February 2025; doi:10.1038/s41569-025-01130-5 In this Roadmap, Stellos and colleagues discuss the mechanisms of cardiovascular system ageing and how the ageing of blood, vessels and heart relates to the decline in organ function, and highlight potential therapeutic interventions, challenges in ageing research and future directions for preclinical and clinical studies.
In tricuspid valve regurgitation, a complex condition that Cedars-Sinai experts regularly treat, the valve between two heart chambers on the right side doesn't open or close properly. Image by Getty. tim.hodson Tue, 02/18/2025 - 10:08 Feb. 13, 2025 Research from Cedars-Sinai investigators and collaborators at other leading medical institutions is helping to provide more treatment options to people living with tricuspid valve disease.
BackgroundLimited evidence exists regarding the association between oxidative stress induced by dietary and lifestyle factors and cardiovascular diseases (CVDs).MethodsWe conducted a weighted analysis using data from 13,530 adults in the National Health and Nutrition Examination Survey (NHANES), covering the period from 2003 to 2018. The total oxidative balance score (OBS) was derived from 20 oxidative stress-related exposures, including dietary and lifestyle factors.
tim.hodson Tue, 02/18/2025 - 16:17 Feb. 11, 2025 UltraSight, a company committed to enhancing the efficiency and productivity of cardiac ultrasound,recentlyannounced support from Bristol Myers Squibb (BMS) for a study that aims to improve access to echocardiographic assessments for patients with obstructive hypertrophic cardiomyopathy (oHCM). Cardiac ultrasound is routinely used as an essential tool in the diagnosis and management of oHCM.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
IntroductionCellular senescence can cause heart failure. However, studies on diagnostic markers related to cellular senescence in acute myocardial infarction (AMI) have not been reported. Therefore, this study explores the mechanism of key genes related to cellular senescence in acute myocardial infarction (AMI) through a bioinformatics approach.MethodsAMI related datasets were obtained from gene expression omnibus (GEO) database, and 3,058 cellular senescence related genes (CSRGs) were extracte
DALLAS, Feb. 18, 2025 About 90% of U.S. adults meet the criteria for a newly recognized syndrome that comes from a combination of heart disease, kidney disease, type 2 diabetes and obesity.[1] This cluster of chronic health conditions is called.
Patent ductus arteriosus (PDA) is one of the most common forms of congenital heart disease (CHD). Infectious endocarditis (IE) is a rare but serious complication of PDA. PDA combined with pulmonary artery aneurysm (PAA) due to IE is rare in children. In this report, we report a rare pediatric PDA case, complicated with PAA due to IE. Transcatheter closure of PDA without the surgical intervention of PAA was performed, with a favorable prognosis.
Patent ductus arteriosus (PDA) is one of the most common forms of congenital heart disease (CHD). Infectious endocarditis (IE) is a rare but serious complication of PDA. PDA combined with pulmonary artery aneurysm (PAA) due to IE is rare in children. In this report, we report a rare pediatric PDA case, complicated with PAA due to IE. Transcatheter closure of PDA without the surgical intervention of PAA was performed, with a favorable prognosis.
Dual SGLT1/2 inhibition with sotagliflozin significantly reduced both heart attacks and stroke in a prespecified secondary analysis of the SCORED trial.
DALLAS, Feb. 18, 2025 Five regions in the U.S. have been selected to implement a new preventive health initiative to improve care for people with a cluster of chronic conditions known as cardiovascular-kidney-metabolic (CKM) syndrome. Through the.
This quality improvement study estimates the prevalence of vasomotor dysfunction in patients with angina and no obstructive coronary artery disease who were clinically referred for a coronary function test; and investigates the safety and feasibility of this test in the Netherlands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT).
A study found many patients with chronic spontaneous urticaria need add-on or higher-dose therapies, revealing gaps in treatment. Findings will be presented at AAAAI 2025.
For patients with atrial fibrillation, the risk of stroke or heart attack from stopping anticoagulants usually outweighs the risk of bleeding, according to new findings from the University of Bath.
You may have heard that people who feel faint should sit with their heads between their knees, but is that true? And how can you tell whether you or someone else who has fainted should go to the emergency department or perhaps even see a cardiologist? Elijah Behr, M.D., a cardiologist at Mayo Clinic Healthcare in London, explains five things it is important to know about fainting.
The EARLY TAVR trial results demonstrate that early transcatheter aortic valve implantation in patients with asymptomatic severe aortic stenosis is superior to clinical surveillance in significantly reducing the composite primary outcome of death, stroke, or unplanned hospitalization for cardiovascular causes.
About 90% of U.S. adults meet the criteria for a newly recognized syndrome that comes from a combination of heart disease, kidney disease, type 2 diabetes and obesity. This cluster of chronic health conditions is called cardiovascular-kidney-metabolic (CKM) syndrome. It can be prevented by paying attention to four health factors, according to scientific experts at the American Heart Association, a global force changing the future of health for all.
Frailty is a common geriatric syndrome associated with many adverse health outcomes. Identifying the risk factors of frailty is crucial and the insulin resistance (IR) is considered as a potential target. The.
An AI-powered patient screening tool helped heart failure researchers at Mass General Brigham cut down on the time required to screen patients for clinical trial eligibility, according to a study published Feb. 17 in JAMA.
The FDA decision to approve the supplemental biologics license application for dupilumab (Dupixent) follows recent pivotal clinical trial data assessing 106 patients.
Chronic thromboembolic pulmonary hypertension (CTEPH) is a severely progressive disease that leads to right heart failure and death. Previous studies have shown that diabetes and insulin resistance (IR) are cl.
Using a data-driven approach, six clusters with different risk profiles and burden of complications were recently identified in middle-aged people before the diagnosis of type 2 diabetes (T2D). We aimed to inv.
The hypoxia/reoxygenation (H/R)-induced pyroptosis of cardiomyocytes plays a crucial role in the pathogenesis of myocardial infarction (MI). miR-155-5p represents a promising target for MI therapy. However, it.
tim.hodson Tue, 02/18/2025 - 16:41 Feb. 17, 2025 The International Consortium for Health Outcomes Measurement (ICHOM) has developed a globally inclusive standard dataset of 16 patient-centered outcome measures for people with heart valve disease, regardless of treatment (surgical or transcatheter procedure), according to a new report published in the American Heart Associations journal Circulation: Cardiovascular Quality & Outcomes.
BackgroundCoagulopathy and inflammatory response are the intractable complication during Sun's procedure for type A aortic dissection (AAD). This study aims to investigate the efficacy of autologous platelet rich plasma (aPRP) on the patients undergoing Sun's procedure under moderate hypothermia.MethodsA total of 372 AAD patients who underwent Sun's procedure under moderate hypothermia were divided into aPRP group (aPRP was separated before heparinization and transfused after protamine neutraliz
ObjectiveA significant proportion (85%) of low-risk non-ST-elevation acute coronary syndrome (NSTE-ACS) patients do not receive objective confirmation of ischemia by stress echocardiography (SE), yet remain a healthcare burden due to lower long-term survival and overuse of medical services. We aimed to identify non-ischemic phenotypes in low-risk NSTE-ACS patients by analyzing a wide range of parameters available during exercise SE.MethodsInpatients [n=103, median age 56 (4665)years, 65 (63%) me
(MedPage Today) -- Johnson & Johnson said the U.S. rollout of the Varipulse pulsed field ablation platform is back on after an investigation found the devices operate as intended. Can artificial intelligence (AI) identify underlying atrial.
Thoracic aortic aneurysm and dissection (TAAD) significantly impact cardiovascular morbidity and mortality. A large subset of TAAD cases, particularly those with an earlier onset, is linked to heritable genetic defects. Despite progress in characterizing genes associated with both syndromic and non-syndromic heritable TAAD, the causative gene remains unknown in most cases.
An international task force has developed standards for tracking outcome measures of patients with heart valve disease, a condition which is expected to double in prevalence by 2040. The standards were published Feb. 17 in Circulation: Cardiovascular Quality & Outcomes.
A patient with decompensated liver cirrhosis treated with Namodenoson under a compassionate use program experienced improvements in disease at 20 months.
Philadelphia-based Jefferson Health has appointed Joseph Bavaria, MD, as executive director of the Bruce & Robbi Toll Heart and Vascular Institute and chair of the department of cardiac surgery at Thomas Jefferson University's Sidney Kimmel Medical College, also in Philadelphia.
A 4-month-old male infant (weight 6kg, height 67cm) with heart failure was diagnosed with an isolated 8.9mm right coronary artery fistula draining into the left ventricle (LV), identified via transthoracic echocardiography and computed tomography angiography. The large, tortuous, and aneurysmal fistula was treated using a minimally invasive percoronary approach, avoiding the high risks of surgery and the challenges of percutaneous closure.
A team at New York City-based NYU Langone successfully implanted the world's smallest pacemaker into a newborn baby suffering from a congenital complete heart block.
Panelists discuss the safety of biologics in atopic dermatitis (AD), reviewing current understanding of their safety profiles, including long-term data, adverse events, and the overall risk-benefit analysis for patients using these agents.
52
52
Input your email to sign up, or if you already have an account, log in here!
Enter your email address to reset your password. A temporary password will be e‑mailed to you.
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
69 
Let's personalize your content