Wed.Jan 24, 2024

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Targeted scientific research projects to demonstrate effectiveness of ‘food is medicine’ in health care

American Heart News - Heart News

DALLAS, Jan. 24, 2024 — In an effort to identify effective food is medicine approaches for incorporating healthy food into health care delivery, the American Heart Association, the world’s leading voluntary organization focused on heart and brain health.

Research 137
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Ibuprofen Fails Another Crack at Reducing Preemie Lung Issues and Deaths

Med Page Today

(MedPage Today) -- Ibuprofen again failed to improve short-term outcomes when used to close patent ductus arteriosus (PDA) in newborns, the placebo-controlled Baby-OSCAR trial showed. Administered parenterally a few days after infants were born.

Outcomes 139
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Harnessing skin cancer genes to heal hearts

Medical Xpress - Cardiology

Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.

Cancer 119
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Breast Cancer Drug Repurposed for Infant With Congenital Hyperinsulinism

Med Page Today

(MedPage Today) -- A 4-month-old with congenital hyperinsulinism responded well to off-label treatment with a breast cancer drug, researchers reported. A newborn presented with severe congenital hyperinsulinism due to homozygous deletion of the.

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Global Trends in Cardiovascular Diseases: Insights from the 2023 Almanac

Cardiology Update

In 2020, a collaboration involving the Journal of the American College of Cardiology (JACC), the National Heart, Lung, and Blood Institute (NHLBI), and the Institute for Health Metrics and Evaluation (IHME) was formed to focus on CVD trends. The 2023 Almanac results derived from the Global Burden of Disease (GBD) and spanning 1990 to 2022, were recently published in the Journal of American College of Cardiology.

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Most US Adults Fail to Recognize Heart Disease as Leading Killer of Americans, Study Finds

HCPLive

The American Heart Association's annual report on heart disease and stroke statistics for 2024 sheds new light on the impact and level of public education surrounding the impact of heart disease and stroke in the US and abroad.

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Spotlight on Advancements in Mitral Valve Repair, Research

DAIC

You may not know Carol Barr, but in the future, she could save your life. Barr’s death at 39 from sudden cardiac arrest was caused by mitral valve prolapse—a heart valve defect that can affect the heart’s ability to pump blood. It can, in some cases, lead to death. Now, thanks to the cardiovascular advances in research and Opportunities Legacy (CAROL) Act—legislation named in honor of Barr that allocates funding through the National Heart, Lung, and Blood Institute to study heart valve disease

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Simona Zannetti, MD, Returns to Lead Medtronic Aortic Business

DAIC

Simona Zannetti, MD milla1cf Wed, 01/24/2024 - 19:02 January 24, 2024 — Medtronic announced the recent appointment of Simona Zannetti, MD , as the General Manager of its Aortic business. Simona, who spent 21 years at Medtronic, returns after a successful stint as the SVP of clinical research at Penumbra , where she helped drive the strategic and commercial business goals of the company as a member of the senior leadership team.

Aortic 105
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Telemedicine Reduced After COVID-19 Peak, Mental Health Video Visits on Rise

HCPLive

In August 2023, 34.5% of mental health visits took place via video, and 10% of primary and subspecialty occurred via telemedicine (including video and/or telephone).

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Post-pandemic, US cardiovascular death rate continues upward trajectory

Medical Xpress - Cardiology

New research confirms what public health leaders have been fearing: The significant uptick in the cardiovascular disease (CVD) death rate that began in 2020 has continued. The continuing trend reverses improvements achieved in the decade before the COVID-19 pandemic to reduce mortalities from heart disease and stroke, the leading causes of death in the United States.

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Higher Rates of Respiratory Distress Seen Among Infants Affected by Maternal COVID-19 Infection

HCPLive

This research sheds light on increasing concerns related to maternal COVID-19 infection and its impact on neonates.

COVID-19 111
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New signaling pathway uncovered, shedding fresh light on atherosclerosis

Science Daily - Stroke

A team has demonstrated new mechanisms that are involved in the development of inflammatory cardiovascular diseases.

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CardioSignal Looks to Expand CVD Detection through Patients Phones

CardiacWire

Expanding access to heart disease detection is one of cardiology’s biggest challenges, and Finnish startup CardioSignal just raised $10M to address that challenge using one of the most accessible devices in the world – the smartphone. CardioSignal uses a proprietary algorithm that analyzes heart motion data produced by smartphones when placed on patients’ chests.

AFIB 75
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2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

Circulation, Ahead of Print. BACKGROUND:The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, and obesity) and health factors (cholesterol, blood pressure, glucose control, and metabolic syndrome) that contribute to cardiovascular health.

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Gene behind heart defects in Down syndrome identified

Medical Xpress - Cardiology

Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21.

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Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual Patient Data Meta-Analysis of Four Randomized Clinical Trials of 58?464 Patients With Atrial Fibrillation

Circulation

Circulation, Ahead of Print. BACKGROUND:The efficacy and safety of non–vitamin-K antagonist oral anticoagulants (NOACs) across the spectrum of body mass index (BMI) and body weight (BW) remain uncertain.METHODS:We analyzed data from COMBINE AF (A Collaboration Between Multiple Institutions to Better Investigate Non-Vitamin K Antagonist Oral Anticoagulant Use in Atrial Fibrillation), which pooled patient-level data from the 4 pivotal randomized trials of NOAC versus warfarin in patients with atri

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Prospective Multicenter International Registry of Ultrasound-Facilitated Catheter-Directed Thrombolysis in Intermediate-High and High-Risk Pulmonary Embolism (KNOCOUT PE)

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Prior clinical trials have demonstrated the efficacy of ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute intermediate-risk pulmonary embolism (PE) using reduced thrombolytic doses and shorter infusion durations. However, utilization and safety of such strategies in broader PE populations remain unclear.

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Wearable Digital Health Technologies for Monitoring in Cardiovascular Medicine

The New England Journal of Medicine

This article reviews the use of digital wearable technologies for monitoring of three common cardiovascular conditions: hypertension, heart failure, and atrial fibrillation.

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Helping aspiring clinicians understand a virtual heart before they work with a real one

Medical Xpress - Cardiology

Jonathan Awori, MD, MS, MFA, isn't embarrassed to say it took him a long time to completely understand the intricate workings of the heart. He says he isn't alone; many aspiring doctors and nurses don't immediately grasp the heart's complexity from two-dimensional textbooks or even 3D-printed models.

Nursing 63
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Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen

The New England Journal of Medicine

Early treatment with ibuprofen for a large patent ductus arteriosus did not result in a lower risk of death or moderate or severe bronchopulmonary dysplasia than placebo at 36 weeks of postmenstrual age.

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Identification of pyroptosis-associated genes with diagnostic value in calcific aortic valve disease

Frontiers in Cardiovascular Medicine

Background Calcific aortic valve disease (CAVD) is one of the most prevalent valvular diseases and is the second most common cause for cardiac surgery. However, the mechanism of CAVD remains unclear. This study aimed to investigate the role of pyroptosis-related genes in CAVD by performing comprehensive bioinformatics analysis. Methods Three microarray datasets (GSE51472, GSE12644 and GSE83453) and one RNA sequencing dataset (GSE153555) were obtained from the Gene Expression Omnibus (GEO) databa

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Climate Change and Eczema: Spotlighting Hazards, Trends, Gaps in Awareness

HCPLive

This study contributes to existing climate change data by exploring climatic hazards and their relationship with atopic dermatitis, in addition to highlighting research gaps and future predictions.

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Is sarcopenia an associated factor of increased administration of specific medications in patients with heart failure? A systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

Background There is controversy in relation to commonly used drugs in heart failure (HF) and their impact on muscle function. The aim of this study was to evaluate the odds of receiving specific medications often used in clinical practice by patients with HF and sarcopenia vs. without sarcopenia. Methods A systematic literature search of cohort studies via databases (PubMed, Web of Science, Scopus, and Cochrane Library) was conducted from inception until March 2023.

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Heart disease still America's top killer, although the death rate has declined

Medical Xpress - Cardiology

Heart disease remains the top cause of death in the United States, but progress is being made and more lives are being saved, a new report finds.

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Harnessing skin cancer genes to heal hearts

Science Daily - Heart Disease

Biomedical engineers have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart. The genetic mutation in the protein BRAF, a part of the MAPK signaling pathway that can promote cell division, is one of the most common and most aggressive found in melanoma patients. In a new study, researchers show that introducing this mutation to rat heart tissue grown in a laboratory can induce growth.

Cancer 63
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Online Survey Reveals Perspectives, Desires for Understanding in Patients with Fibromyalgia

HCPLive

Thematic analysis revealed common themes, including uncertainty about the cause of fibromyalgia, feelings of invisibility, confusion about symptoms and flares, and a strong desire for more accessible treatment information.

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2 heart specialties see 6% drop in board pass rates — COVID may be to blame

Becker's Hospital Review - Cardiology

More cardiologists are failing to pass their boards, and COVID-19 disruptions could be the main reason why, Medscape reported Jan. 23.

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Meta-Analysis Suggests Benefit of Electroacupuncture in Acute Gouty Arthritis

HCPLive

A review of 15 RCTS suggests that both electroacupuncture and conventional drugs demonstrate similar effectiveness in addressing pain for patients with acute gouty arthritis.

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Unveiling the Future of Diagnosis: AI's Promise and Peril in Healthcare

Physiologically Speaking

This week’s post is an in-depth discussion about the hopeful and cautious sides of artificial intelligence in healthcare. It’s written by my good friend Zach Salyers with whom I attended undergraduate and graduate school. Zach is currently a Lab Project Coordinator at Medpace and is interested in the emerging space of artificial intelligence in healthcare, so I thought he’d be the perfect person to write about the state-of-the-art in this area.

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Rheumatoid Arthritis Quiz: TNF Inhibitors

HCPLive

How well do patients with rheumatoid arthritis adhere to treatment with a TNF inhibitor and how likely and long lasting is remission? Test your knowledge with this quiz.

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Post pandemic, U.S. cardiovascular death rate continues upward trajectory

Science Daily - Heart Disease

New research confirms what public health leaders have been fearing: the significant uptick in the cardiovascular disease (CVD) death rate that began in 2020 has continued. The continuing trend reverses improvements achieved in the decade before the COVID-19 pandemic to reduce mortalities from heart disease and stroke, the leading causes of death in the United States.

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Study on the efficacy and safety of neoadjuvant immunotherapy combined with chemotherapy regimen for III–IVA esophageal squamous cell carcinoma post-surgery

Journal of Cardiothoracic Surgery

The treatment of esophageal squamous cell carcinoma is still controversial, and neoadjuvant chemotherapy combined with immunotherapy is a hot topic of current research. We investigated the recent efficacy and.

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Gene behind heart defects in Down syndrome identified

Science Daily - Heart Disease

Researchers have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21. Reducing the overactivity of this gene partially reversed these defects in mice, setting the scene for potential future therapies for heart conditions in people with Down syndrome.

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2024 STS Mastering Valve Surgery Workshop

Society of Thoracic Surgeons - Allied Health

Event 2024 STS Mastering Valve Surgery Workshop gtrainyte Wed, 01/24/2024 - 09:21 Event dates Sep 20–21, 2024 Location Chicago, IL Add your name to the interest list if you would like to be informed when registration opens.

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2024 STS Boot Camp

Society of Thoracic Surgeons - Early Career

Event 2024 STS Boot Camp gtrainyte Wed, 01/24/2024 - 10:30 Event dates Aug 22–25, 2024 Location Chicago, IL The STS Boot Camp is designed to provide an experiential foundation and hands-on practice in basic cardiothoracic operating skills. Resident participants will receive expert instruction and utilize simulators that enhance the learning experience by replicating real-world cases and emergency scenarios.

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2024 STS Perioperative & Critical Care Conference

Society of Thoracic Surgeons - Allied Health

Event 2024 STS Perioperative & Critical Care Conference gtrainyte Wed, 01/24/2024 - 09:29 Event dates Oct 25–26, 2024 Location Philadelphia, PA Add your name to the interest list if you would like to be informed when registration opens.

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Latest Medical News: Partial Heart Transplant of an Infant

Wellnest

Introduction: Wellnest brings you , the latest medical news where an infant successfully received a partial heart transplant! In a remarkable leap forward for pediatric cardiac care, a groundbreaking partial heart transplant procedure has emerged as a beacon of hope for infants facing severe congenital heart conditions. This innovative technique not only provides functional heart valves for neonates but also offers the promise of lifelong solutions, transforming the landscape of pediatric heart