Fri.Jun 28, 2024

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Expansion of AstraZeneca’s Flagship Health Equity Program Healthy Heart Africa

DAIC

milla1cf Fri, 06/28/2024 - 19:07 June 28, 2024 — AstraZeneca has set out a new ambition for Healthy Heart Africa , its flagship health equity initiative, to target a broader range of non-communicable diseases (NCDs), including chronic kidney disease (CKD) as well as hypertension and cardiovascular disease. The expanded program will also launch in Egypt, reaching even more patients across the continent.

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A More Selective Enoxaparin Thromboprophylaxis Protocol May Be Safer for New Moms

Med Page Today

(MedPage Today) -- A more selective risk-stratified approach to postpartum enoxaparin (Lovenox) thromboprophylaxis for venous thromboembolism (VTE) was linked to reduced rates of wound hematomas without increasing the rate of VTE, according to.

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Gender Gaps in Cardiovascular Disease Diagnosis and Treatment Persist

DAIC

Getty Images milla1cf Fri, 06/28/2024 - 08:10 June 27, 2024 — Cardiovascular disease is the leading cause of death for women, and gaps in care and access persist between women and men. Addressing those gaps could lead to an increase of at least 1.6 million years of quality life and boost the U.S. economy by $28 billion annually by 2040, according to a new report published today by the American Heart Association and the McKinsey Health Institute (MHI).

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New 52-Week Data Highlights Benefits of Tildrakizumab for Psoriasis

HCPLive

These real-world findings on tildrakizumab’s use among patients with moderate-to-severe plaque psoriasis highlight the drug’s efficacy regarding high burden symptoms.

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Study Defines the Process of and Defenses Against Cardiac Valve Calcification

DAIC

Partially calcified valve leaflet tissue, including unaltered collagen (blue), calcified collagen (yellow to red) and aggregated calcium phosphate nodules. Image provided by Mayandi Sivaguru and Bruce Fouke, Roy, J. Carver Biotechnology Center, University of Illinois milla1cf Fri, 06/28/2024 - 08:14 June 27, 2024 — The human body has sophisticated defenses against the deposition of calcium minerals that stiffen heart tissues, researchers at the University of Illinois Urbana-Champaign and collabo

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Mechanism of Action of Elamipretide for GA in Dry AMD

HCPLive

Arshad Khanani, MD describes the mechanism of action of elamipretide, an investigational product candidate for geographic atrophy in dry age-related macular degeneration.

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Researchers develop an alternative to pacemakers in the form of a hydrogel

Medical Xpress - Cardiology

A heart attack is a life-threatening condition, with patients remaining at risk of premature death long after the actual attack—50% to 60% of patients die subsequently as a result of sudden cardiac death, triggered by cardiac arrhythmia.

More Trending

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To Forgive, Divine

The New England Journal of Medicine

When a resident misses a contraindication and makes a potentially serious error, her attending consoles her with the story of an early mistake of his own. Such healing conversations are still too rare.

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Transesophageal echocardiography related complications

Frontiers in Cardiovascular Medicine

Transesophageal Echocardiography (TEE) is an important imaging method for the evaluation of cardiac structure and function, and it holds significant value in the clinical management of cardiovascular diseases. Unlike transthoracic echocardiography (TTE), which is non-invasive, TEE involves semi-invasive intracavity operations, leading to increasing attention to its safety and potential complications.

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Why Soul Span Matters More Than Lifespan

Dr. Paddy Barrett

In the cathedrals of our minds resides the quality of our lives. In this inner sanctum, we experience every moment and memory of our lives. Whatever the duration of our lives or the degree of physical or cognitive quality we possess, it is how we experience our lives that matter most. Fundamentally, the quality of our minds dictates the quality of our lives.

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Physiology Friday #224: Does Protein Timing Matters for Gains in Strength and Hypertrophy?

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. ICYMI: I appeared as a guest on Siim Land’s podcast to chat about all things VO2 max. You can watch the YouTube video here. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication.

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Prioritizing Health | Improving Care of Patients With Hypertensive Disorders of Pregnancy

American College of Cardiology

As the field of reproductive and maternal health has grown, awareness about the impact of hypertension during and after pregnancy on future cardiovascular health has also increased.

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Ozanimod Effective, Durable in Patients with Ulcerative Colitis Naive to Advanced Therapy

HCPLive

Findings from a post hoc analysis of True North and its open-label extension highlight ozanimod’s rapid onset of action and durability in advanced therapy-naive patients with UC.

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Roles of non-coding RNA in diabetic cardiomyopathy

Cardiovascular Diabetology

In recent years, the incidence of diabetes has been increasing rapidly, posing a serious threat to human health. Diabetic cardiomyopathy (DCM) is characterized by cardiomyocyte hypertrophy, myocardial fibrosis.

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Impact of Early Rhythm Control and Healthy Lifestyles in AF Patients

American College of Cardiology

What is the combined effect of early rhythm control (ERC) and healthy lifestyles (HLS) on the risk of ischemic stroke in patients with atrial fibrillation (AF)?

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Urate-Lowering Takes Longer to Improve Quality of Life in Tophaceous Gout

HCPLive

A study presented at EULAR 2024 suggests tophaceous gout patients may benefit from a longer pegloticase treatment course alongside urate-lowering therapy.

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Clinical Significance of SVT During Pregnancy in Healthy Women

American College of Cardiology

What is the prevalence, the management, and the association between supraventricular tachycardias (SVTs) and adverse obstetric outcomes?

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Nonlinear association between atherogenic index of plasma and type 2 diabetes mellitus in overweight and obesity patients: evidence from Chinese medical examination data

Cardiovascular Diabetology

The atherogenic index of plasma (AIP) is closely associated with the onset of diabetes, with obesity being a significant risk factor for type 2 diabetes mellitus (T2DM). However, the association between the AI.

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Colchicine for Prevention of Vascular Inflammation in Non-Cardioembolic Stroke

American College of Cardiology

The goal of the CONVINCE trial was to evaluate long-term colchicine compared with usual care among patients with nonsevere ischemic stroke or transient ischemic attack (TIA).

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Impaired GK-GKRP interaction rather than direct GK activation worsens lipid profiles and contributes to long-term complications: a Mendelian randomization study

Cardiovascular Diabetology

Glucokinase (GK) plays a key role in glucose metabolism. In the liver, GK is regulated by GK regulatory protein (GKRP) with nuclear sequestration at low plasma glucose level. Some GK activators (GKAs) disrupt.

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Change in HRS Board of Trustees

DAIC

Jodie L. Hurwitz, MD, FHRS, and Kenneth A. Ellenbogen, MD, FHRS. milla1cf Fri, 06/28/2024 - 19:05 June 28, 2024 — After a year of dedicated service and outstanding leadership, Jodie L. Hurwitz , MD, FHRS, has now ended her role as HRS President. HRS extends its deepest gratitude to Dr. Hurwitz for her invaluable contributions and commitment to the success of HRS throughout her tenure.

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8 in 8: Fast-Tracking the CABG Patient

Society of Thoracic Surgeons - Congenital

Video 8 in 8: Fast-Tracking the CABG Patient kchalko Fri, 06/28/2024 - 15:51 This 8 in 8 session focuses on fast-tracking in CABG patients. The presentation examines incorporating elements of ERAS and other fast track principles, data regarding the safety and efficacy of fast tracking, and a real-world patient case. Speaker Alison F. Ward, MD, Emory University, Atlanta, GA The Society’s 8 in 8 Series offers quick access to important topics in cardiothoracic surgery.

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Engineered exosomes: a potential therapeutic strategy for septic cardiomyopathy

Frontiers in Cardiovascular Medicine

Septic cardiomyopathy, a life-threatening complication of sepsis, can cause acute heart failure and carry a high mortality risk. Current treatments have limitations. Fortunately, engineered exosomes, created through bioengineering technology, may represent a potential new treatment method. These exosomes can both diagnose and treat septic cardiomyopathy, playing a crucial role in its development and progression.

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5 Simple Steps to Enhance Your Cardiac Health

MIBHS

Maintaining good cardiac health is essential for a long and fulfilling life. Your heart is the engine that keeps your body running smoothly, so it’s crucial to take care of it. Fortunately, improving your cardiac health doesn’t have to be complicated. By implementing a few simple lifestyle changes, you can significantly reduce your risk of heart disease and improve your overall well-being.

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Biograph Trinion PET/CT Scanner Cleared by FDA

Cassling

Advanced scanner with ultra-fast time of flight and unique air-cooled design Sustainable imaging platform with low total cost of ownership Addresses all clinical needs, including oncology, theranostics, cardiology, and neurology Siemens Healthineers announces the Food and Drug Administration clearance of the Biograph Trinion, a high-performance, energy-efficient positron emission tomography/computed tomography (PET/CT) scanner with a wide range of clinical capabilities and a low lifetime operati

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Canakinumab Prophylaxis Resolves Active Gout Flares Within 48 Hours

HCPLive

Administering canakinumab prophylaxis before a pegloticase infusion prevents new gout glares induced by pegloticase + methotrexate treatment.

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Does Coffee Raise Blood Pressure or Risk for Hypertension?

NEJM Journal Watch - Cardiology

A cohort study shows no obvious effect on BP after 10 years of consumption.

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What Does Elamipretide Represent for GA in Dry AMD?

HCPLive

Arshad Khanani, MD points to the viability of the mechanism of action of elamipretide for geographic atrophy in dry AMD, and what it could represent for patient outcomes.

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Effects of Different Doses of Sildenafil for Pulmonary Arterial Hypertension

American College of Cardiology

For the treatment of pulmonary arterial hypertension (PAH), is sildenafil 80 mg TID noninferior to sildenafil 5 mg TID for all-cause mortality?

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Study Highlights Barriers in Access to Biologics Among Psoriasis Patients

HCPLive

In this analysis, disparities associated with race, old age, socioeconomic differences, and rural residence were highlighted as examples.

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ACC CardiaCast: 2024 Update to the AHA/ACC HCM Guideline: Expert Interpretation for Application to Practice

American College of Cardiology

In this episode of CardiaCast, world-renowned hypertrophic cardiomyopathy (HCM) expert Dr. Matthew Martinez will review changes occurring in the field of HCM and explore best practice recommendations from the newly issued guideline.

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Concluding Thoughts on Elamipretide for GA in Dry AMD

HCPLive

Arshad Khanani, MD shares his excitement about the potential of elamipretide joining the treatment armamentarium in GA and his final thoughts on the topic.

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FDA Update: Cordella Pulmonary Artery Sensor System Receives Premarket Approval

American College of Cardiology

The U.S. Food and Drug Administration (FDA) on June 24 gave premarket approval for Endotronix, Inc.’s Cordella™ Pulmonary Artery Sensor System for the treatment of patients with NYHA class III heart failure (HF).

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Mirum Pharmaceuticals Submits NDA for Chenodiol Tablets in Cerebrotendinous Xanthomatosis

HCPLive

Mirum Pharmaceuticals submitted an NDA for chenodiol tablets to treat CTX based on positive phase 3 RESTORE trial results.

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Healthy Lifestyle and Likelihood of Becoming a Centenarian

American College of Cardiology

What is the association between modifiable lifestyle factors and the likelihood of becoming a centenarian in individuals aged ≥80 years?

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Advancing Elamipretide into Phase 3 ReNEW and ReGAIN Trials

HCPLive

Arshad Khanani, MD provides insight into the pivotal Phase 3 clinical trials investigating elamipretide for geographic atrophy in dry AMD.

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Quality Improvement For Institutions | Enhancing Practice and Patient Outcomes With NCDR’s Real-World Data

American College of Cardiology

ACC's NCDR suite of registries is a robust source of data for researchers, and a critical component in continuing to help hospitals, practices and clinicians advance the quality of cardiovascular care and improve patient outcomes for all.